Immunovirological analyses of chronically simian immunodeficiency virus SIVmnd-1- and SIVmnd-2-infected mandrills (mandrillus sphinx)

Journal of Virology

Volumn 85, Issue 24, 2011, Pages 13077-13087

  Apetrei, Cristian ^a   Sumpter, Beth ^b,c   Souquiere, Sandrine ^d   Chahroudi, Ann ^c   Makuwa, Maria ^d   Reed, Patricia ^d   Ribeiro, Ruy M ^e   Pandrea, Ivona ^a   Roques, Pierre ^d,f   Silvestri, Guido ^b,c  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c EMORY UNIVERSITY   (United States)

^d CENTRE INTERNATIONAL DE RECHERCHES MÉDICALES DE FRANCEVILLE   (Gabon)

^e LOS ALAMOS NATIONAL LABORATORY   (United States)

^f CEA   (France)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CD4 LYMPHOCYTE COUNT; CD8+ T LYMPHOCYTE; CHRONIC DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; DISEASE DURATION; EVIDENCE BASED MEDICINE; IMMUNOASSAY; IMMUNOPATHOGENESIS; IMMUNOREACTIVITY; LYMPH NODE CELL; LYMPHOCYTE DEPLETION; LYMPHOCYTE PROLIFERATION; MANDRILLUS; NATURAL HOST; NONHUMAN; PERIPHERAL LYMPHOCYTE; PHENOTYPIC VARIATION; PRIORITY JOURNAL; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; T LYMPHOCYTE ACTIVATION; VIRUS LOAD; VIRUS REPLICATION;

ANIMALS; APOPTOSIS; BLOOD; CD4 LYMPHOCYTE COUNT; CELL PROLIFERATION; CROSS-SECTIONAL STUDIES; LYMPH NODES; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MANDRILLUS; PRIMATE DISEASES; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; VIRAL LOAD;

ANIMALIA; CERCOPITHECUS AETHIOPS; MANDRILLUS SPHINX; PRIMATES; SIMIAN IMMUNODEFICIENCY VIRUS; SIMIAN IMMUNODEFICIENCY VIRUS - MND;

EID: 84855846939     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.05693-11     Document Type: Article

References (71)

1. Apetrei, C., et al. 2010. Pattern of SIVagm infection in patas monkeys suggests that host adaptation to simian immunodeficiency virus infection may result in resistance to infection and virus extinction. J. Infect. Dis. 202(Suppl. 3):S371-S376.
2. Apetrei, C., et al. 2004. Direct inoculation of simian immunodeficiency virus from sooty mangabeys in black mangabeys (Lophocebus aterrimus): first evidence of AIDS in a heterologous African species and different pathologic outcomes of experimental infection. J. Virol. 78:11506-11518.
3. Bailes, E., et al. 2003. Hybrid origin of SIV in chimpanzees. Science 300:1713.
4. Beaumier, C. M., et al. 2009. CD4 downregulation by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection. Nat. Med. 15:879-885.
5. Beer, B. E., et al. 1999. Simian immunodeficiency virus (SIV) from sun-tailed monkeys (Cercopithecus solatus): evidence for host-dependent evolution of SIV within the C. lhoesti superspecies. J. Virol. 73:7734-7744.
6. Beer, B. E., et al. 2001. Characterization of novel simian immunodeficiency viruses from red-capped mangabeys from Nigeria (SIVrcmNG409 and-NG411). J. Virol. 75:12014-12027.
7. Bosinger, S. E., et al. 2009. Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys. J. Clin. Invest. 119:3556-3572.
8. Brenchley, J. M., G. Silvestri, and D. C. Douek. 2010. Nonprogressive and progressive primate immunodeficiency lentivirus infections. Immunity 32:737-742.
9. Clewley, J. P., J. C. Lewis, D. W. Brown, and E. L. Gadsby. 1998. A novel simian immunodeficiency virus (SIVdrl) pol sequence from the drill monkey, Mandrillus leucophaeus. J. Virol. 72:10305-10309.
10. Dunham, R., et al. 2006. The AIDS-resistance of naturally SIV-infected sooty mangabeys is independent of cellular immunity to the virus. Blood 108:209-217.
11. Estaquier, J., et al. 1994. Programmed cell death and AIDS: significance of T-cell apoptosis in pathogenic and nonpathogenic primate lentiviral infections. Proc. Natl. Acad. Sci. U. S. A. 91:9431-9435.
12. Favre, D., et al. 2009. Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection. PLoS Pathog. 5:e1000295.
13. Gaufin, T., et al. 2009. Effect of B cell depletion on viral replication and clinical outcome of SIV infection in a natural host. J. Virol. 83:10347-10357.
14. Gaufin, T., et al. 2010. Experimental depletion of CD8_ cells in acutely SIVagm-infected African green monkeys results in increased viral replication. Retrovirology 7:42.
15. Georges-Courbot, M. C., et al. 1998. Natural infection of a household pet red-capped mangabey (Cercocebus torquatus torquatus) with a new simian immunodeficiency virus. J. Virol. 72:600-608.
16. Goldstein, S., et al. 2006. Comparison of simian immunodeficiency virus SIVagmVer replication and CD4_ T cell dynamics in vervet and sabaeus African green monkeys. J. Virol. 80:4868-4877.
17. Goldstein, S., et al. 2005. Plateau levels of viremia correlate with the degree of CD4_ T cell loss in simian immunodeficiency virus SIVagm-infected pigtailed macaques: variable pathogenicity of natural SIVagm isolates. J. Virol. 79:5153-5162.
18. Gordon, S., et al. 2008. Short-lived infected cells support the bulk of virus replication in naturally SIV-infected sooty mangabeys: implications for AIDS pathogenesis. J. Virol. 82:3725-3735.
19. + T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys. J. Immunol. 179:3026-3034.
20. Hazenberg, M. D., et al. 2000. T cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation: a longitudinal analysis in patients before and during highly active antiretroviral therapy (HAART). Blood 95:249-255.
21. Hirsch, V. M., et al. 1999. Characterization of a novel simian immunodeficiency virus (SIV) from L'Hoest monkeys (Cercopithecus l'hoesti): implications for the origins of SIVmnd and other primate lentiviruses. J. Virol. 73:1036-1045.
22. Hirsch, V. M., et al. 1995. Induction of AIDS by simian immunodeficiency virus from an African green monkey: species-specific variation in pathogenicity correlates with the extent of in vivo replication. J. Virol. 69:955-967.
23. Hu, J., et al. 2003. Characterization and comparison of recombinant simian immunodeficiency virus from drill (Mandrillus leucophaeus) and mandrill (Mandrillus sphinx) isolates. J. Virol. 77:4867-4880.
24. Hurtrel, B., et al. 2005. Apoptosis in SIV infection. Cell Death Differ. 12(Suppl. 1):979-990.
25. Kaur, A., et al. 2001. Emergence of cytotoxic T lymphocyte escape mutations in nonpathogenic simian immunodeficiency virus infection. Eur. J. Immunol. 31:3207-3217.
26. Kaur, A., et al. 2000. Identification of multiple simian immunodeficiency virus (SIV)-specific CTL epitopes in sooty mangabeys with natural and experimentally acquired SIV infection. J. Immunol. 164:934-943.
27. Keele, B. F., et al. 2006. Chimpanzee reservoirs of pandemic and nonpandemic HIV-1. Science 313:523-526.
28. Kornfeld, C., et al. 2005. Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS. J. Clin. Invest. 115:1082-1091.
29. McClure, H. M., et al. 1989. Spectrum of disease in macaque monkeys chronically infected with SIV/SMM. Vet. Immunol. Immunopathol. 21:13-24.
30. + cell numbers during the early phase of experimental infection with simian immunodeficiency virus SIVmnd-1 in Mandrillus sphinx. J. Virol. 76:10256-10263.
31. Onanga, R., et al. 2006. Primary simian immunodeficiency virus SIVmnd-2 infection in mandrills (Mandrillus sphinx). J. Virol. 80:3303-3309.
32. + T cells in HIV-infected individuals. J. Immunol. 174:2900-2909.
33. + T cells are associated with limited CCR5 expression. Nat. Med. 17:830-836.
34. Paiardini, M., et al. 2009. T cell phenotypic and functional changes associated with social subordination and gene polymorphisms in the serotonin reuptake transporter in female rhesus monkeys. Brain Behav. Immun. 23:286-293.
35. Pandrea, I., and C. Apetrei. 2010. Where the wild things are: pathogenesis of SIV infection in African nonhuman primate hosts. Curr. HIV/AIDS Rep. 7:28-36.
36. Pandrea, I., et al. 2006. Simian immunodeficiency virus (SIV) SIVagm.sab infection of Caribbean African green monkeys: new model of the study of SIV pathogenesis in natural hosts J. Virol. 80:4858-4867.
37. + T cells is a typical feature of natural SIV hosts. Blood 109:1069-1076.
38. + T cell depletion. J. Immunol. 181:6687-6691.
39. + T cells is not predictive of SIV virulence. J. Immunol. 179:3035-3046.
40. Pandrea, I., et al. 2005. Impact of viral factors on very early in vivo replication profiles in SIVagm-infected African green monkeys. J. Virol. 79:6249-6259.
41. Pandrea, I., et al. 2003. High levels of SIVmnd-1 replication in chronically infected Mandrillus sphinx. Virology 317:119-127.
42. Pandrea, I., et al. 2001. Chronic SIV infection ultimately causes immunodeficiency in African non-human primates. AIDS 15:2461-2462.
43. + T cells may prevent breastfeeding transmission of SIV in natural non-human primate hosts J. Virol. 82:5501-5509.
44. Pandrea, I., et al. 2008. Simian immunodeficiency virus SIVagm dynamics in African green monkeys. J. Virol. 82:3713-3724.
45. Pandrea, I., G. Silvestri, and C. Apetrei. 2009. AIDS in African nonhuman primate hosts of SIVs: a new paradigm of SIV infection. Curr. HIV Res. 6:57-72.
46. Pandrea, I., et al. 2006. Simian immunodeficiency viruses replication dynamics in African non-human primate hosts: common patterns and speciesspecific differences. J. Med. Primatol. 35:194-201.
47. Pandrea, I., D. L. Sodora, G. Silvestri, and C. Apetrei. 2008. Into the wild: simian immunodeficiency virus (SIV) infection in natural hosts. Trends Immunol. 29:419-428.
48. Pitcher, C. J., et al. 2002. Development and homeostasis of T cell memory in rhesus macaque. J. Immunol. 168:29-43.
49. Plantier, J. C., et al. 2009. A new human immunodeficiency virus derived from gorillas. Nat. Med. 15:871-872.
50. + T lymphocytes in HIV-1 infection as measured by Ki-67 antigen. J. Exp. Med. 187:1295-1303.
51. Santiago, M. L., et al. 2005. Simian immunodeficiency virus infection in free-ranging sooty mangabeys (Cercocebus atys atys) from the Tai Forest, Cote d'Ivoire: implications for the origin of epidemic human immunodeficiency virus type 2. J. Virol. 79:12515-12527.
52. Schmitz, J. E., et al. 2009. Inhibition of adaptive immune responses leads to a fatal clinical outcome in SIV-infected pigtailed macaques but not vervet African green monkeys. PLoS Pathog. 5:e1000691.
53. Silvestri, G. 2005. Naturally SIV-infected sooty mangabeys: are we closer to understanding why they do not develop AIDS? J. Med. Primatol. 34:243-252.
54. Silvestri, G., et al. 2005. Divergent host responses during primary simian immunodeficiency virus SIVsm infection of natural sooty mangabey and nonnatural rhesus macaque hosts. J. Virol. 79:4043-4054.
55. Silvestri, G., M. Paiardini, I. Pandrea, M. M. Lederman, and D. L. Sodora. 2007. Understanding the benign nature of SIV infection in natural hosts. J. Clin. Invest. 117:3148-3154.
56. Silvestri, G., et al. 2003. Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic highlevel viremia. Immunity 18:441-452.
57. Sodora, D. L., et al. 2009. Towards an AIDS vaccine: lessons from natural SIV infections of African nonhuman primate hosts. Nat. Med. 15:861-865.
58. Sodora, D. L., and G. Silvestri. 2008. Immune activation and AIDS pathogenesis. AIDS 22:439-446.
59. Souquiere, S., et al. 2001. Wild Mandrillus sphinx are carriers of two types of lentivirus. J. Virol. 75:7086-7096.
60. Souquière, S., et al. 2009. SIVmnd-1 and SIVmnd-2 have different pathogenic potentials in Rhesus macaques upon experimental cross-species transmission. J. Gen. Virol. 90:488-499.
61. + T cell homeostasis during natural, nonpathogenic simian immunodeficiency virus infection of sooty mangabeys: implications for AIDS pathogenesis. J. Immunol. 178:1680-1691.
62. Takehisa, J., et al. 2001. Natural infection of wild-born mandrills (Mandrillus sphinx) with two different types of simian immunodeficiency virus. AIDS Res. Hum. Retroviruses 17:1143-1154.
63. Tsujimoto, H., et al. 1988. Isolation and characterization of simian immunodeficiency virus from mandrills in Africa and its relationship to other human and simian immunodeficiency viruses. J. Virol. 62:4044-4050.
64. Tsujimoto, H., et al. 1989. Sequence of a novel simian immunodeficiency virus from a wild-caught African mandrill. Nature 341:539-541.
65. VandeWoude, S., and C. Apetrei. 2006. Going wild: lessons from T-lymphotropic naturally occurring lentiviruses. Clin. Microbiol. Rev. 19:728-762.
66. Van Heuverswyn, F., et al. 2006. Human immunodeficiency viruses: SIV infection in wild gorillas. Nature 444:164.
67. Vinton, C., et al. 2011. CD4-like immunological function by CD4 T cells in multiple natural hosts of simian immunodeficiency virus. J. Virol. 85:8702-8708.
68. Wang, Z., B. Metcalf, R. M. Ribeiro, H. McClure, and A. Kaur. 2006. Th-1-type cytotoxic CD8_ T lymphocyte responses to simian immunodeficiency virus (SIV) are a consistent feature of natural SIV infection in sooty mangabeys. J. Virol. 80:2771-2783.
69. Worobey, M., et al. 2010. Island biogeography reveals the deep history of SIV. Science 330:1487.
70. + T cell responses in chronically SIVagm-infected vervet African green monkeys. J. Virol. 82:11577-11588.
71. Zahn, R. C., et al. 2010. Suppression of adaptive immune responses during primary SIV infection of sabaeus African green monkeys delays partial containment of viremia but does not induce disease. Blood 115:3070-3078.