Glucocorticoid-induced tethered transrepression requires SUMOylation of GR and formation of a SUMO-SMRT/NCoR1-HDAC3 repressing complex

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 5, 2016, Pages E635-E643

  Hua, Guoqiang ^a   Ganti, Krishna Priya ^a   Chambon, Pierre ^a,b,c  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c l'alimentation et l'Environnement   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HISTONE DEACETYLASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; RECEPTOR INTERACTING PROTEIN 140; SILENCING MEDIATOR OF RETINOID AND THYROID HORMONE RECEPTOR; SUMO PROTEIN; DEXAMETHASONE; HISTONE DEACETYLASE; LIGAND; NCOR1 PROTEIN, MOUSE; NCOR2 PROTEIN, MOUSE; REPRESSOR PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DERMATITIS; KERATINOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUMOYLATION; TRANSACTIVATION; ANIMAL; METABOLISM; MUTANT MOUSE STRAIN;

ANIMALS; DEXAMETHASONE; HISTONE DEACETYLASES; LIGANDS; MICE; MICE, MUTANT STRAINS; NUCLEAR RECEPTOR CO-REPRESSOR 1; NUCLEAR RECEPTOR CO-REPRESSOR 2; RECEPTORS, GLUCOCORTICOID; REPRESSOR PROTEINS; SMALL UBIQUITIN-RELATED MODIFIER PROTEINS; SUMOYLATION;

EID: 84956663291     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1522826113     Document Type: Article

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