GR SUMOylation and formation of an SUMO-SMRT/ NCoR1-HDAC3 repressing complex is mandatory for GC-induced IR nGRE-mediated transrepression

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 5, 2016, Pages E626-E634

  Hua, Guoqiang ^a   Paulen, Laetitia ^a   Chambon, Pierre ^a,b,c  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c l'alimentation et l'Environnement   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID RECEPTOR; GLYCOGEN SYNTHASE KINASE 3BETA; HISTONE DEACETYLASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RECEPTOR INTERACTING PROTEIN 140; SILENCING MEDIATOR OF RETINOID AND THYROID HORMONE RECEPTOR; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; SUPPRESSOR OF CYTOKINE SIGNALING 3; THYMIC STROMAL LYMPHOPOIETIN; TRANSCRIPTION FACTOR AP 1; UPSTREAM STIMULATORY FACTOR 1; GLUCOCORTICOID; HISTONE DEACETYLASE; NCOR1 PROTEIN, MOUSE; NCOR2 PROTEIN, MOUSE; PROTEIN BINDING; REPRESSOR PROTEIN; STAT3 PROTEIN, MOUSE; SUMO PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CRYSTAL STRUCTURE; DNA BINDING; EXON; GENE REPRESSION; GENETIC CONSERVATION; HYDROGEN BOND; IN VITRO STUDY; INVERTED REPEAT; INVERTED REPEATED NEGATIVE RESPONSE ELEMENT; KERATINOCYTE; LIGAND BINDING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN SYNTHESIS INHIBITION; REGULATORY MECHANISM; SUMOYLATION; TRANSACTIVATION; TRANSCRIPTION REGULATION; ANIMAL; GENETICS; METABOLISM;

ANIMALS; GLUCOCORTICOIDS; HISTONE DEACETYLASES; MICE; NUCLEAR RECEPTOR CO-REPRESSOR 1; NUCLEAR RECEPTOR CO-REPRESSOR 2; PROTEIN BINDING; RECEPTORS, GLUCOCORTICOID; REPRESSOR PROTEINS; SMALL UBIQUITIN-RELATED MODIFIER PROTEINS; STAT3 TRANSCRIPTION FACTOR; SUMOYLATION;

EID: 84956654316     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1522821113     Document Type: Article

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