Aminoacyl β-naphthylamides as substrates and modulators of AcrB multidrug efflux pump

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 5, 2016, Pages 1405-1410

  Kinana, Alfred D ^a   Vargiu, Attilio V ^b   May, Thithiwat ^a,c   Nikaido, Hiroshi ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CAGLIARI   (Italy)

^c NITTO DENKO CORPORATION   (Japan)

Author keywords

Efflux inhibitors; Molecular dynamics simulations; Phe Arg naphthylamide; RND transporters

Indexed keywords

2 NAPHTHYLAMINE; AMINO ACID; ARGININE; NITROCEFIN; 2-NAPHTHYLAMIDE; ACRB PROTEIN, E COLI; ESCHERICHIA COLI PROTEIN; MULTIDRUG RESISTANCE PROTEIN; NAPHTHALENE DERIVATIVE;

ARTICLE; BINDING AFFINITY; BINDING SITE; ESCHERICHIA COLI; FLUORESCENCE; HYDROLYSIS; MOLECULAR DYNAMICS; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; ENZYME SPECIFICITY; KINETICS; METABOLISM;

ESCHERICHIA COLI PROTEINS; KINETICS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NAPHTHALENES; SUBSTRATE SPECIFICITY;

EID: 84956630889     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1525143113     Document Type: Article

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