The internal gene duplication and interrupted coding sequences in the MmpL genes of Mycobacterium tuberculosis: Towards understanding the multidrug transport in an evolutionary perspective

International Journal of Medical Microbiology

Volumn 305, Issue 3, 2015, Pages 413-423

  Sandhu, Padmani ^a   Akhter, Yusuf ^a  

^a CENTRAL UNIVERSITY OF HIMACHAL PRADESH   (India)

Author keywords

Efflux pumps; MmpL genes; Multidrug resistance; Mycobacterium tuberculosis; Reductive evolution; RND transporters

Indexed keywords

BACTERIAL PROTEIN; MYCOBACTERIAL MEMBRANE PROTEIN LARGE; UNCLASSIFIED DRUG; CARRIER PROTEIN; TUBERCULOSTATIC AGENT;

ARTICLE; COMPUTER MODEL; GENE DUPLICATION; GENE SEQUENCE; MEMBRANE COMPONENT; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; ACTIVE TRANSPORT; AMINO ACID SEQUENCE; ANTIBIOTIC RESISTANCE; BIOLOGICAL MODEL; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; CLUSTER ANALYSIS; DNA SEQUENCE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MICROBIOLOGY; MOLECULAR EVOLUTION; MOLECULAR GENETICS; PHYLOGENY; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY; TUBERCULOSIS;

AMINO ACID SEQUENCE; ANTITUBERCULAR AGENTS; BIOLOGICAL TRANSPORT, ACTIVE; CELL MEMBRANE; CLUSTER ANALYSIS; DRUG RESISTANCE, BACTERIAL; EVOLUTION, MOLECULAR; GENE DUPLICATION; HUMANS; MEMBRANE TRANSPORT PROTEINS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; MYCOBACTERIUM TUBERCULOSIS; PHYLOGENY; PROTEIN CONFORMATION; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; TUBERCULOSIS;

EID: 84955696002     PISSN: 14384221     EISSN: 16180607     Source Type: Journal    
DOI: 10.1016/j.ijmm.2015.03.005     Document Type: Article

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