-
1
-
-
84859171807
-
MYC on the path to cancer
-
Dang CV. MYC on the path to cancer. Cell 2012; 149: 22-35.
-
(2012)
Cell
, vol.149
, pp. 22-35
-
-
Dang, C.V.1
-
2
-
-
13944252067
-
The life cycle of C-myc: From synthesis to degradation
-
Sears RC. The life cycle of C-myc: from synthesis to degradation. Cell Cycle 2004; 3: 1133-1137.
-
(2004)
Cell Cycle
, vol.3
, pp. 1133-1137
-
-
Sears, R.C.1
-
4
-
-
84867021989
-
Transcriptional amplification in tumor cells with elevated c-Myc
-
Lin CY, Loven J, Rahl PB, Paranal RM, Burge CB, Bradner JE et al. Transcriptional amplification in tumor cells with elevated c-Myc. Cell 2012; 151: 56-67.
-
(2012)
Cell
, vol.151
, pp. 56-67
-
-
Lin, C.Y.1
Loven, J.2
Rahl, P.B.3
Paranal, R.M.4
Burge, C.B.5
Bradner, J.E.6
-
5
-
-
0024160809
-
Activation of c-myc by woodchuck hepatitis virus insertion in hepatocellular carcinoma
-
Hsu T, Moroy T, Etiemble J, Louise A, Trepo C, Tiollais P et al. Activation of c-myc by woodchuck hepatitis virus insertion in hepatocellular carcinoma. Cell 1988; 55: 627-635.
-
(1988)
Cell
, vol.55
, pp. 627-635
-
-
Hsu, T.1
Moroy, T.2
Etiemble, J.3
Louise, A.4
Trepo, C.5
Tiollais, P.6
-
6
-
-
79951861412
-
Post-translational control of Myc function during differentiation
-
Conacci-Sorrell M, Eisenman RN. Post-translational control of Myc function during differentiation. Cell Cycle 2011; 10: 604-610.
-
(2011)
Cell Cycle
, vol.10
, pp. 604-610
-
-
Conacci-Sorrell, M.1
Eisenman, R.N.2
-
7
-
-
0027417593
-
Transactivation of gene expression by Myc is inhibited by mutation at the phosphorylation sites Thr-58 and Ser-62
-
Gupta S, Seth A, Davis RJ. Transactivation of gene expression by Myc is inhibited by mutation at the phosphorylation sites Thr-58 and Ser-62. Proc Natl Acad Sci USA 1993; 90: 3216-3220.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 3216-3220
-
-
Gupta, S.1
Seth, A.2
Davis, R.J.3
-
8
-
-
0034306997
-
Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability
-
Sears R, Nuckolls F, Haura E, Taya Y, Tamai K, Nevins JR. Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. Genes Dev 2000; 14: 2501-2514.
-
(2000)
Genes Dev
, vol.14
, pp. 2501-2514
-
-
Sears, R.1
Nuckolls, F.2
Haura, E.3
Taya, Y.4
Tamai, K.5
Nevins, J.R.6
-
9
-
-
2942650133
-
The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation
-
Welcker M, Orian A, Jin J, Grim JE, Harper JW, Eisenman RN et al. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation. Proc Natl Acad Sci USA 2004; 101: 9085-9090.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 9085-9090
-
-
Welcker, M.1
Orian, A.2
Jin, J.3
Grim, J.E.4
Harper, J.W.5
Eisenman, R.N.6
-
10
-
-
33645232372
-
Protein phosphatase 2A regulatory subunit B56alpha associates with c-myc and negatively regulates c-myc accumulation
-
Arnold HK, Sears RC. Protein phosphatase 2A regulatory subunit B56alpha associates with c-myc and negatively regulates c-myc accumulation. Mol Cell Biol 2006; 26: 2832-2844.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2832-2844
-
-
Arnold, H.K.1
Sears, R.C.2
-
11
-
-
84880651314
-
Pin1 regulates the dynamics of c-Myc DNA binding to facilitate target gene regulation and oncogenesis
-
Farrell AS, Pelz C, Wang X, Daniel CJ, Wang Z, Su Y et al. Pin1 regulates the dynamics of c-Myc DNA binding to facilitate target gene regulation and oncogenesis. Mol Cell Biol 2013; 33: 2930-2949.
-
(2013)
Mol Cell Biol
, vol.33
, pp. 2930-2949
-
-
Farrell, A.S.1
Pelz, C.2
Wang, X.3
Daniel, C.J.4
Wang, Z.5
Su, Y.6
-
12
-
-
2942693567
-
Myc degradation: Dancing with ubiquitin ligases
-
Amati B. Myc degradation: dancing with ubiquitin ligases. Proc Natl Acad Sci USA 2004; 101: 8843-8844.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 8843-8844
-
-
Amati, B.1
-
13
-
-
2942614705
-
Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7
-
Yada M, Hatakeyama S, Kamura T, Nishiyama M, Tsunematsu R, Imaki H et al. Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7. EMBO J 2004; 23: 2116-2125.
-
(2004)
EMBO J
, vol.23
, pp. 2116-2125
-
-
Yada, M.1
Hatakeyama, S.2
Kamura, T.3
Nishiyama, M.4
Tsunematsu, R.5
Imaki, H.6
-
14
-
-
84863115732
-
Mechanistic insight into Myc stabilization in breast cancer involving aberrant Axin1 expression
-
Zhang X, Farrell AS, Daniel CJ, Arnold H, Scanlan C, Laraway BJ et al. Mechanistic insight into Myc stabilization in breast cancer involving aberrant Axin1 expression. Proc Natl Acad Sci USA 2012; 109: 2790-2795.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 2790-2795
-
-
Zhang, X.1
Farrell, A.S.2
Daniel, C.J.3
Arnold, H.4
Scanlan, C.5
Laraway, B.J.6
-
15
-
-
2342526543
-
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells
-
Yeh E, Cunningham M, Arnold H, Chasse D, Monteith T, Ivaldi G et al. A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells. Nat Cell Biol 2004; 6: 308-318.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 308-318
-
-
Yeh, E.1
Cunningham, M.2
Arnold, H.3
Chasse, D.4
Monteith, T.5
Ivaldi, G.6
-
16
-
-
84868671065
-
Regulation of c-Myc protein abundance by a protein phosphatase 2A-glycogen synthase kinase 3beta-negative feedback pathway
-
Liu L, Eisenman RN. Regulation of c-Myc protein abundance by a protein phosphatase 2A-glycogen synthase kinase 3beta-negative feedback pathway. Genes Cancer 2012; 3: 23-36.
-
(2012)
Genes Cancer
, vol.3
, pp. 23-36
-
-
Liu, L.1
Eisenman, R.N.2
-
17
-
-
78249287240
-
B55beta-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer
-
Tan J, Lee PL, Li Z, Jiang X, Lim YC, Hooi SC et al. B55beta-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer. Cancer Cell 2010; 18: 459-471.
-
(2010)
Cancer Cell
, vol.18
, pp. 459-471
-
-
Tan, J.1
Lee, P.L.2
Li, Z.3
Jiang, X.4
Lim, Y.C.5
Hooi, S.C.6
-
18
-
-
62049085035
-
The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc
-
Arnold HK, Zhang X, Daniel CJ, Tibbitts D, Escamilla-Powers J, Farrell A et al. The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc. EMBO J 2009; 28: 500-512.
-
(2009)
EMBO J
, vol.28
, pp. 500-512
-
-
Arnold, H.K.1
Zhang, X.2
Daniel, C.J.3
Tibbitts, D.4
Escamilla-Powers, J.5
Farrell, A.6
-
19
-
-
84903449080
-
Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer
-
Janghorban M, Farrell AS, Allen-Petersen BL, Pelz C, Daniel CJ, Oddo J et al. Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer. Proc Natl Acad Sci USA 2014; 111: 9157-9162.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 9157-9162
-
-
Janghorban, M.1
Farrell, A.S.2
Allen-Petersen, B.L.3
Pelz, C.4
Daniel, C.J.5
Oddo, J.6
-
20
-
-
0032703317
-
Cloning and characterization of B delta, a novel regulatory subunit of protein phosphatase 2A
-
Strack S, Chang D, Zaucha JA, Colbran RJ, Wadzinski BE. Cloning and characterization of B delta, a novel regulatory subunit of protein phosphatase 2A. FEBS Lett 1999; 460: 462-466.
-
(1999)
FEBS Lett
, vol.460
, pp. 462-466
-
-
Strack, S.1
Chang, D.2
Zaucha, J.A.3
Colbran, R.J.4
Wadzinski, B.E.5
-
21
-
-
0030296869
-
Molecular mechanisms of the protein serine/threonine phosphatases
-
Barford D. Molecular mechanisms of the protein serine/threonine phosphatases. Trends Biochem Sci 1996; 21: 407-412.
-
(1996)
Trends Biochem Sci
, vol.21
, pp. 407-412
-
-
Barford, D.1
-
22
-
-
70350340056
-
Serine/threonine phosphatases: Mechanism through structure
-
Shi Y. Serine/threonine phosphatases: mechanism through structure. Cell 2009; 139: 468-484.
-
(2009)
Cell
, vol.139
, pp. 468-484
-
-
Shi, Y.1
-
23
-
-
33751538328
-
Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1
-
Zhang Y, Kim Y, Genoud N, Gao J, Kelly JW, Pfaff SL et al. Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1. Mol Cell 2006; 24: 759-770.
-
(2006)
Mol Cell
, vol.24
, pp. 759-770
-
-
Zhang, Y.1
Kim, Y.2
Genoud, N.3
Gao, J.4
Kelly, J.W.5
Pfaff, S.L.6
-
24
-
-
0038168110
-
A novel RNA polymerase II C-terminal domain phosphatase that preferentially dephosphorylates serine 5
-
Yeo M, Lin PS, Dahmus ME, Gill GN. A novel RNA polymerase II C-terminal domain phosphatase that preferentially dephosphorylates serine 5. J Biol Chem 2003; 278: 26078-26085.
-
(2003)
J Biol Chem
, vol.278
, pp. 26078-26085
-
-
Yeo, M.1
Lin, P.S.2
Dahmus, M.E.3
Gill, G.N.4
-
25
-
-
58649104000
-
Small C-terminal domain phosphatase enhances snail activity through dephosphorylation
-
Wu Y, Evers BM, Zhou BP. Small C-terminal domain phosphatase enhances snail activity through dephosphorylation. J Biol Chem 2009; 284: 640-648.
-
(2009)
J Biol Chem
, vol.284
, pp. 640-648
-
-
Wu, Y.1
Evers, B.M.2
Zhou, B.P.3
-
26
-
-
33846028557
-
Small C-terminal domain phosphatases dephosphorylate the regulatory linker regions of Smad2 and Smad3 to enhance transforming growth factor-beta signaling
-
Wrighton KH, Willis D, Long J, Liu F, Lin X, Feng XH. Small C-terminal domain phosphatases dephosphorylate the regulatory linker regions of Smad2 and Smad3 to enhance transforming growth factor-beta signaling. J Biol Chem 2006; 281: 38365-38375.
-
(2006)
J Biol Chem
, vol.281
, pp. 38365-38375
-
-
Wrighton, K.H.1
Willis, D.2
Long, J.3
Liu, F.4
Lin, X.5
Feng, X.H.6
-
27
-
-
33646950265
-
PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling
-
Lin X, Duan X, Liang YY, Su Y, Wrighton KH, Long J et al. PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling. Cell 2006; 125: 915-928.
-
(2006)
Cell
, vol.125
, pp. 915-928
-
-
Lin, X.1
Duan, X.2
Liang, Y.Y.3
Su, Y.4
Wrighton, K.H.5
Long, J.6
-
28
-
-
0037648338
-
Skp2 regulates Myc protein stability and activity
-
Kim SY, Herbst A, Tworkowski KA, Salghetti SE, Tansey WP. Skp2 regulates Myc protein stability and activity. Mol Cell 2003; 11: 1177-1188.
-
(2003)
Mol Cell
, vol.11
, pp. 1177-1188
-
-
Kim, S.Y.1
Herbst, A.2
Tworkowski, K.A.3
Salghetti, S.E.4
Tansey, W.P.5
-
29
-
-
77951978532
-
Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis
-
Chan CH, Lee SW, Li CF, Wang J, Yang WL, Wu CY et al. Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis. Nat Cell Biol 2010; 12: 457-467.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 457-467
-
-
Chan, C.H.1
Lee, S.W.2
Li, C.F.3
Wang, J.4
Yang, W.L.5
Wu, C.Y.6
-
30
-
-
20444479428
-
C-Myc-regulated microRNAs modulate E2F1 expression
-
O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT. c-Myc-regulated microRNAs modulate E2F1 expression. Nature 2005; 435: 839-843.
-
(2005)
Nature
, vol.435
, pp. 839-843
-
-
O'Donnell, K.A.1
Wentzel, E.A.2
Zeller, K.I.3
Dang, C.V.4
Mendell, J.T.5
-
31
-
-
0036159130
-
Direct interaction of c-Myc with Smad2 and Smad3 to inhibit TGF-beta-mediated induction of the CDK inhibitor p15 (Ink4B)
-
Feng XH, Liang YY, Liang M, Zhai W, Lin X. Direct interaction of c-Myc with Smad2 and Smad3 to inhibit TGF-beta-mediated induction of the CDK inhibitor p15 (Ink4B). Mol Cell 2002; 9: 133-143.
-
(2002)
Mol Cell
, vol.9
, pp. 133-143
-
-
Feng, X.H.1
Liang, Y.Y.2
Liang, M.3
Zhai, W.4
Lin, X.5
-
32
-
-
0027204282
-
Gene-regulatory properties of Myc helix-loop-helix/leucine zipper mutants: Max-dependent DNA binding and transcriptional activation in yeast correlates with transforming capacity
-
Crouch DH, Fisher F, Clark W, Jayaraman PS, Goding CR, Gillespie DA. Gene-regulatory properties of Myc helix-loop-helix/leucine zipper mutants: Max-dependent DNA binding and transcriptional activation in yeast correlates with transforming capacity. Oncogene 1993; 8: 1849-1855.
-
(1993)
Oncogene
, vol.8
, pp. 1849-1855
-
-
Crouch, D.H.1
Fisher, F.2
Clark, W.3
Jayaraman, P.S.4
Goding, C.R.5
Gillespie, D.A.6
-
33
-
-
23144452431
-
GPS: A comprehensive www server for phosphorylation sites prediction
-
Xue Y, Zhou F, Zhu M, Ahmed K, Chen G, Yao X. GPS: a comprehensive www server for phosphorylation sites prediction. Nucleic Acids Res 2005; 33: W184-W187.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. W184-W187
-
-
Xue, Y.1
Zhou, F.2
Zhu, M.3
Ahmed, K.4
Chen, G.5
Yao, X.6
-
34
-
-
33947103658
-
A curated compendium of phosphorylation motifs
-
Amanchy R, Periaswamy B, Mathivanan S, Reddy R, Tattikota SG, Pandey A. A curated compendium of phosphorylation motifs. Nat Biotechnol 2007; 25: 285-286.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 285-286
-
-
Amanchy, R.1
Periaswamy, B.2
Mathivanan, S.3
Reddy, R.4
Tattikota, S.G.5
Pandey, A.6
-
35
-
-
56749184298
-
Reflecting on 25 years with MYC
-
Meyer N, Penn LZ. Reflecting on 25 years with MYC. Nat Rev Cancer 2008; 8: 976-990.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 976-990
-
-
Meyer, N.1
Penn, L.Z.2
-
36
-
-
84859167179
-
Deregulated MYC expression induces dependence upon AMPK-related kinase 5
-
Liu L, Ulbrich J, Muller J, Wustefeld T, Aeberhard L, Kress TR et al. Deregulated MYC expression induces dependence upon AMPK-related kinase 5. Nature 2012; 483: 608-612.
-
(2012)
Nature
, vol.483
, pp. 608-612
-
-
Liu, L.1
Ulbrich, J.2
Muller, J.3
Wustefeld, T.4
Aeberhard, L.5
Kress, T.R.6
-
37
-
-
79551552058
-
Phosphorylation regulates c-Myc's oncogenic activity in the mammary gland
-
Wang X, Cunningham M, Zhang X, Tokarz S, Laraway B, Troxell M et al. Phosphorylation regulates c-Myc's oncogenic activity in the mammary gland. Cancer Res 2011; 71: 925-936.
-
(2011)
Cancer Res
, vol.71
, pp. 925-936
-
-
Wang, X.1
Cunningham, M.2
Zhang, X.3
Tokarz, S.4
Laraway, B.5
Troxell, M.6
-
38
-
-
84867010006
-
C-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells
-
Nie Z, Hu G, Wei G, Cui K, Yamane A, Resch W et al. c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells. Cell 2012; 151: 68-79.
-
(2012)
Cell
, vol.151
, pp. 68-79
-
-
Nie, Z.1
Hu, G.2
Wei, G.3
Cui, K.4
Yamane, A.5
Resch, W.6
-
39
-
-
12844250536
-
Small CTD. Phosphatases function in silencing neuronal gene expression
-
Yeo M, Lee SK, Lee B, Ruiz EC, Pfaff SL, Gill GN, Small CTD. phosphatases function in silencing neuronal gene expression. Science 2005; 307: 596-600.
-
(2005)
Science
, vol.307
, pp. 596-600
-
-
Yeo, M.1
Lee, S.K.2
Lee, B.3
Ruiz, E.C.4
Pfaff, S.L.5
Gill, G.N.6
-
40
-
-
14844325341
-
Subtype-specific regulation of equilibrative nucleoside transporters by protein kinase CK2
-
Stolk M, Cooper E, Vilk G, Litchfield DW, Hammond JR. Subtype-specific regulation of equilibrative nucleoside transporters by protein kinase CK2. Biochem J 2005; 386: 281-289.
-
(2005)
Biochem J
, vol.386
, pp. 281-289
-
-
Stolk, M.1
Cooper, E.2
Vilk, G.3
Litchfield, D.W.4
Hammond, J.R.5
-
41
-
-
0034604726
-
Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells
-
Song DH, Sussman DJ, Seldin DC. Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells. J Biol Chem 2000; 275: 23790-23797.
-
(2000)
J Biol Chem
, vol.275
, pp. 23790-23797
-
-
Song, D.H.1
Sussman, D.J.2
Seldin, D.C.3
-
42
-
-
77953310667
-
The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs
-
Liu N, Li H, Li S, Shen M, Xiao N, Chen Y et al. The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs. J Biol Chem 2010; 285: 18858-18867.
-
(2010)
J Biol Chem
, vol.285
, pp. 18858-18867
-
-
Liu, N.1
Li, H.2
Li, S.3
Shen, M.4
Xiao, N.5
Chen, Y.6
-
43
-
-
84957547236
-
A positive feedback loop between EBP2 and c-Myc regulates rDNA transcription, cell proliferation, and tumorigenesis
-
Liao P, Wang W, Shen M, Pan W, Zhang K, Wang R et al. A positive feedback loop between EBP2 and c-Myc regulates rDNA transcription, cell proliferation, and tumorigenesis. Cell Death Dis 2014; 5: e1032.
-
(2014)
Cell Death Dis
, vol.5
-
-
Liao, P.1
Wang, W.2
Shen, M.3
Pan, W.4
Zhang, K.5
Wang, R.6
-
44
-
-
77951587359
-
Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase
-
Zhang M, Liu J, Kim Y, Dixon JE, Pfaff SL, Gill GN et al. Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1. Protein Sci 2010; 19: 974-986.
-
(2010)
Scp1. Protein Sci
, vol.19
, pp. 974-986
-
-
Zhang, M.1
Liu, J.2
Kim, Y.3
Dixon, J.E.4
Pfaff, S.L.5
Gill, G.N.6
-
45
-
-
0037181170
-
Pin1 modulates the dephosphorylation of the RNA polymerase II C-terminal domain by yeast Fcp1
-
Kops O, Zhou XZ, Lu KP. Pin1 modulates the dephosphorylation of the RNA polymerase II C-terminal domain by yeast Fcp1. FEBS Lett 2002; 513: 305-311.
-
(2002)
FEBS Lett
, vol.513
, pp. 305-311
-
-
Kops, O.1
Zhou, X.Z.2
Lu, K.P.3
|