Small CTD phosphatases function in silencing neuronal gene expression

Science

Volumn 307, Issue 5709, 2005, Pages 596-600

  Yeo, Michele ^a,c   Lee, Soo Kyung ^b,d   Lee, Bora ^b,d   Ruiz, Esmeralda C ^b   Pfaff, Samuel L ^b   Gill, Gordon N ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYMES; NEUROLOGY; PLANTS (BOTANY); RNA; TISSUE;

CARBOXYL-TERMINAL DOMAIN (CTD); GENE EXPRESSION; NEURON-RESTRICTIVE SILENCER FACTOR (NRSF); REPRESSOR ELEMENT 1 (RE-1)-SILENCING TRANSCRIPTION FACTOR (REST); RNA POLYMERASE II (RNAPII);

GENETIC ENGINEERING;

NEURON SPECIFIC SILENCER FACTOR; PHOSPHATASE; REPRESSOR ELEMENT 1 SILENCING TRANSCRIPTION FACTOR; RNA POLYMERASE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ENZYME; GENE EXPRESSION;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; DROSOPHILA; GENE EXPRESSION; GENE REPRESSION; GENE SILENCING; GENETIC CONSERVATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; REPRESSOR GENE; STEM CELL; TRANSCRIPTION REGULATION;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; DNA-BINDING PROTEINS; DOWN-REGULATION; DROSOPHILA; DROSOPHILA PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE SILENCING; HUMANS; IN SITU HYBRIDIZATION; MICE; NERVE TISSUE PROTEINS; NEURONS; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; REGULATORY SEQUENCES, NUCLEIC ACID; REPRESSOR PROTEINS; RNA INTERFERENCE; TCF TRANSCRIPTION FACTORS; TRANSCRIPTION FACTORS; TRETINOIN;

EID: 12844250536     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1100801     Document Type: Article

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26. The authors are grateful to V. Lunyak and I. Kalcheva for helpful advice. S.-K.L. was supported by a fellowship from the Human Frontiers Science Program, and S.L.P was supported by the Helen McLoraine Developmental Chair in Neurobiology and the C. Harold and Leila Y. Mathers Foundation. These studies were supported by NIH grant DK13149 (G.N.G.) and NS37116 (S.L.P.).