Glycomics and glycoproteomics focused on aging and age-related diseases - Glycans as a potential biomarker for physiological alterations

Biochimica et Biophysica Acta - General Subjects

Volumn 1860, Issue 8, 2016, Pages 1608-1614

  Miura, Yuri ^a   Endo, Tamao ^a  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

Aging; Biomarker; Glycomics; Glycoproteomics; Glycosylation; Longevity

Indexed keywords

BIOLOGICAL MARKER; GLYCAN; GLYCOPROTEIN; IMMUNOGLOBULIN;

AGING; ALZHEIMER DISEASE; CARBOHYDRATE ANALYSIS; COGNITIVE DEFECT; DIABETES MELLITUS; DOWN SYNDROME; EHLERS DANLOS SYNDROME; FRAIL ELDERLY; GENETIC ASSOCIATION; GLYCOBIOLOGY; GLYCOPROTEOMICS; GLYCOSYLATION; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; LONGEVITY; MILD COGNITIVE IMPAIRMENT; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NORMOTENSIVE HYDROCEPHALUS; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEOMICS; REVIEW; AGED; ANIMAL; COGNITION DISORDERS; GENETICS; METABOLISM; PROCEDURES; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ANIMALS; BIOMARKERS; COGNITION DISORDERS; DIABETES MELLITUS; FRAIL ELDERLY; GLYCOMICS; GLYCOSYLATION; HUMANS; LONGEVITY; PROTEOMICS;

EID: 84955604732     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2016.01.013     Document Type: Review

References (79)

1. D. Rizzuto, and L. Fratiglioni Lifestyle factors related to mortality and survival: a mini-review Gerontology 60 2014 327 335
2. G.W. Hart, and R.J. Copeland Glycomics hits the big time Cell 143 2010 672 676
3. K. Ohtsubo, and J.D. Marth Glycosylation in cellular mechanisms of health and disease Cell 126 2006 855 867
4. K.S. Lau, and J.W. Dennis N-glycans in cancer progression Glycobiology 18 2008 750 760
5. S. Bohm, D. Kao, and F. Nimmerjahn Sweet and sour: the role of glycosylation for the anti-inflammatory activity of immunoglobulin G Curr. Top. Microbiol. Immunol. 382 2014 393 417
6. F. Dall'Olio, V. Vanhooren, C.C. Chen, P.E. Slagboom, M. Wuhrer, and C. Franceschi N-glycomic biomarkers of biological aging and longevity: a link with inflammaging Ageing Res. Rev. 12 2013 685 698
7. Y. Sato, and T. Endo Alteration of brain glycoproteins during aging Geriatr. Gerontol. Int. 10 Suppl. 1 2010 S32 S40
8. O. Gornik, J. Wagner, M. Pucic, A. Knezevic, I. Redzic, and G. Lauc Stability of N-glycan profiles in human plasma Glycobiology 19 2009 1547 1553
9. H. Korekane, K. Shida, K. Murata, M. Ohue, Y. Sasaki, S. Imaoka, and Y. Miyamoto Evaluation of laser microdissection as a tool in cancer glycomic studies Biochem. Biophys. Res. Commun. 352 2007 579 586
10. L.R. Ruhaak, H.W. Uh, M. Beekman, C.H. Hokke, R.G. Westendorp, J. Houwing-Duistermaat, M. Wuhrer, A.M. Deelder, and P.E. Slagboom Plasma protein N-glycan profiles are associated with calendar age, familial longevity and health J. Proteome Res. 10 2011 1667 1674
11. A. Knezevic, O. Gornik, O. Polasek, M. Pucic, I. Redzic, M. Novokmet, P.M. Rudd, A.F. Wright, H. Campbell, I. Rudan, and G. Lauc Effects of aging, body mass index, plasma lipid profiles, and smoking on human plasma N-glycans Glycobiology 20 2010 959 969
12. W. Laroy, R. Contreras, and N. Callewaert Glycome mapping on DNA sequencing equipment Nat. Protoc. 1 2006 397 405
13. L.R. Ruhaak, C. Huhn, W.J. Waterreus, A.R. de Boer, C. Neususs, C.H. Hokke, A.M. Deelder, and M. Wuhrer Hydrophilic interaction chromatography-based high-throughput sample preparation method for N-glycan analysis from total human plasma glycoproteins Anal. Chem. 80 2008 6119 6126
14. A. Knezevic, O. Polasek, O. Gornik, I. Rudan, H. Campbell, C. Hayward, A. Wright, I. Kolcic, N. O'Donoghue, J. Bones, P.M. Rudd, and G. Lauc Variability, heritability and environmental determinants of human plasma N-glycome J. Proteome Res. 8 2009 694 701
15. M. Wuhrer, A.R. de Boer, and A.M. Deelder Structural glycomics using hydrophilic interaction chromatography (HILIC) with mass spectrometry Mass Spectrom. Rev. 28 2009 192 206
16. M. Pucic, S. Pinto, M. Novokmet, A. Knezevic, O. Gornik, O. Polasek, K. Vlahovicek, W. Wang, P.M. Rudd, A.F. Wright, H. Campbell, I. Rudan, and G. Lauc Common aberrations from the normal human plasma N-glycan profile Glycobiology 20 2010 970 975
17. M. Pucic, A. Knezevic, J. Vidic, B. Adamczyk, M. Novokmet, O. Polasek, O. Gornik, S. Supraha-Goreta, M.R. Wormald, I. Redzic, H. Campbell, A. Wright, N.D. Hastie, J.F. Wilson, I. Rudan, M. Wuhrer, P.M. Rudd, D. Josic, and G. Lauc High throughput isolation and glycosylation analysis of IgG-variability and heritability of the IgG glycome in three isolated human populations Mol. Cell. Proteomics 10 2011 M111 010090
18. N. Callewaert, S. Geysens, F. Molemans, and R. Contreras Ultrasensitive profiling and sequencing of N-linked oligosaccharides using standard DNA-sequencing equipment Glycobiology 11 2001 275 281
19. V. Vanhooren, L. Desmyter, X.E. Liu, M. Cardelli, C. Franceschi, A. Federico, C. Libert, W. Laroy, S. Dewaele, R. Contreras, and C. Chen N-glycomic changes in serum proteins during human aging Rejuvenation Res. 10 2007 521a 531a
20. V. Vanhooren, S. Dewaele, C. Libert, S. Engelborghs, P.P. De Deyn, O. Toussaint, F. Debacq-Chainiaux, M. Poulain, Y. Glupczynski, C. Franceschi, K. Jaspers, I. van der Pluijm, J. Hoeijmakers, and C.C. Chen Serum N-glycan profile shift during human ageing Exp. Gerontol. 45 2010 738 743
21. N. Ding, H. Nie, X. Sun, W. Sun, Y. Qu, X. Liu, Y. Yao, X. Liang, C.C. Chen, and Y. Li Human serum N-glycan profiles are age and sex dependent Age Ageing 40 2011 568 575
22. V. Vanhooren, S. Dewaele, O.M. Kuro, N. Taniguchi, L. Dolle, L.A. van Grunsven, E. Makrantonaki, C.C. Zouboulis, C.C. Chen, and C. Libert Alteration in N-glycomics during mouse aging: a role for FUT8 Aging Cell 10 2011 1056 1066
23. R. Testa, V. Vanhooren, A.R. Bonfigli, M. Boemi, F. Olivieri, A. Ceriello, S. Genovese, L. Spazzafumo, V. Borelli, M.G. Bacalini, S. Salvioli, P. Garagnani, S. Dewaele, C. Libert, and C. Franceschi N-glycomic changes in serum proteins in type 2 diabetes mellitus correlate with complications and with metabolic syndrome parameters PLoS One 10 2015 e0119983
24. L.R. Ruhaak, H.W. Uh, M. Beekman, C.A. Koeleman, C.H. Hokke, R.G. Westendorp, M. Wuhrer, J.J. Houwing-Duistermaat, P.E. Slagboom, and A.M. Deelder Decreased levels of bisecting GlcNAc glycoforms of IgG are associated with human longevity PLoS One 5 2010 e12566
25. Y. Miura, N. Hashii, H. Tsumoto, D. Takakura, Y. Ohta, Y. Abe, Y. Arai, N. Kawasaki, N. Hirose, and T. Endo and SONIC (Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians), Change in N-glycosylation of plasma proteins in Japanese semisupercentenarians PLoS One 10 2015 e0142645
26. I.J. Goldstein, C.E. Hollerman, and E.E. Smith Protein-carbohydrate interaction. II. Inhibition studies on the interaction of concanavalin a with polysaccharides Biochemistry 4 1965 876 883
27. J.B. Owen, F. Di Domenico, R. Sultana, M. Perluigi, C. Cini, W.M. Pierce, and D.A. Butterfield Proteomics-determined differences in the concanavalin-A-fractionated proteome of hippocampus and inferior parietal lobule in subjects with Alzheimer's disease and mild cognitive impairment: implications for progression of AD J. Proteome Res. 8 2009 471 482
28. F. Di Domenico, J.B. Owen, R. Sultana, R.A. Sowell, M. Perluigi, C. Cini, J. Cai, W.M. Pierce, and D.A. Butterfield The wheat germ agglutinin-fractionated proteome of subjects with Alzheimer's disease and mild cognitive impairment hippocampus and inferior parietal lobule: implications for disease pathogenesis and progression J. Neurosci. Res. 88 2010 3566 3577
29. D.A. Butterfield, and J.B. Owen Lectin-affinity chromatography brain glycoproteomics and Alzheimer disease: insights into protein alterations consistent with the pathology and progression of this dementing disorder Proteomics Clin. Appl. 5 2011 50 56
30. K.S. Shamsi, A. Pierce, A.S. Ashton, D.G. Halade, A. Richardson, and S.E. Espinoza Proteomic screening of glycoproteins in human plasma for frailty biomarkers J. Gerontol. A Biol. Sci. Med. Sci. 67 2012 853 864
31. K. Kanninen, G. Goldsteins, S. Auriola, I. Alafuzoff, and J. Koistinaho Glycosylation changes in Alzheimer's disease as revealed by a proteomic approach Neurosci. Lett. 367 2004 235 240
32. C. Sihlbom, P. Davidsson, M. Sjogren, L.O. Wahlund, and C.L. Nilsson Structural and quantitative comparison of cerebrospinal fluid glycoproteins in Alzheimer's disease patients and healthy individuals Neurochem. Res. 33 2008 1332 1340
33. A. Kuno, N. Uchiyama, S. Koseki-Kuno, Y. Ebe, S. Takashima, M. Yamada, and J. Hirabayashi Evanescent-field fluorescence-assisted lectin microarray: a new strategy for glycan profiling Nat. Methods 2 2005 851 856
34. S. Angeloni, J.L. Ridet, N. Kusy, H. Gao, F. Crevoisier, S. Guinchard, S. Kochhar, H. Sigrist, and N. Sprenger Glycoprofiling with micro-arrays of glycoconjugates and lectins Glycobiology 15 2005 31 41
35. K.T. Pilobello, L. Krishnamoorthy, D. Slawek, and L.K. Mahal Development of a lectin microarray for the rapid analysis of protein glycopatterns Chembiochem 6 2005 985 989
36. R. Saldova, M.R. Wormald, R.A. Dwek, and P.M. Rudd Glycosylation changes on serum glycoproteins in ovarian cancer may contribute to disease pathogenesis Dis. Markers 25 2008 219 232
37. S. Chugh, V.S. Gnanapragassam, M. Jain, S. Rachagani, M.P. Ponnusamy, and S.K. Batra Pathobiological implications of mucin glycans in cancer: sweet poison and novel targets Biochim. Biophys. Acta 1856 2015 211 225
38. R.R. Drake, E.E. Jones, T.W. Powers, and J.O. Nyalwidhe Altered glycosylation in prostate cancer Adv. Cancer Res. 126 2015 345 382
39. N. Taniguchi, and Y. Kizuka Glycans and cancer: role of N-glycans in cancer biomarker, progression and metastasis, and therapeutics Adv. Cancer Res. 126 2015 11 51
40. G. Lauc, M. Pezer, I. Rudan, and H. Campbell Mechanisms of disease: the human N-glycome Bochim. Biophys. Acta 1860 2016 1574 1582
41. K. Akasaka-Manya, H. Manya, Y. Sakurai, B.S. Wojczyk, S.L. Spitalnik, and T. Endo Increased bisecting and core-fucosylated N-glycans on mutant human amyloid precursor proteins Glycoconj. J. 25 2008 775 786
42. I. Perdivara, R. Petrovich, B. Allinquant, L.J. Deterding, K.B. Tomer, and M. Przybylski Elucidation of O-glycosylation structures of the beta-amyloid precursor protein by liquid chromatography-mass spectrometry using electron transfer dissociation and collision induced dissociation J. Proteome Res. 8 2009 631 642
43. Y. Kizuka, S. Kitazume, R. Fujinawa, T. Saito, N. Iwata, T.C. Saido, M. Nakano, Y. Yamaguchi, Y. Hashimoto, M. Staufenbiel, H. Hatsuta, S. Murayama, H. Manya, T. Endo, and N. Taniguchi An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease EMBO Mol. Med. 7 2015 175 189
44. W.T. Kimberly, M.J. LaVoie, B.L. Ostaszewski, W. Ye, M.S. Wolfe, and D.J. Selkoe Complex N-linked glycosylated nicastrin associates with active gamma-secretase and undergoes tight cellular regulation J. Biol. Chem. 277 2002 35113 35117
45. T. Tomita, R. Katayama, R. Takikawa, and T. Iwatsubo Complex N-glycosylated form of nicastrin is stabilized and selectively bound to presenilin fragments FEBS Lett. 520 2002 117 121
46. Y. Sato, Y. Naito, I. Grundke-Iqbal, K. Iqbal, and T. Endo Analysis of N-glycans of pathological tau: possible occurrence of aberrant processing of tau in Alzheimer's disease FEBS Lett. 496 2001 152 160
47. S. Schedin-Weiss, B. Winblad, and L.O. Tjernberg The role of protein glycosylation in Alzheimer disease FEBS J. 281 2014 46 62
48. S.J. van Rensburg, P. Berman, F. Potocnik, P. MacGregor, D. Hon, and N. de Villiers 5- and 6-glycosylation of transferrin in patients with Alzheimer's disease Metab. Brain Dis. 19 2004 89 96
49. E. Marklova, Z. Albahri, and M. Valis Microheterogeneity of some serum glycoproteins in neurodegenerative diseases J. Neurol. Sci. 314 2012 20 25
50. M.A. Korolainen, S. Auriola, T.A. Nyman, I. Alafuzoff, and T. Pirttila Proteomic analysis of glial fibrillary acidic protein in Alzheimer's disease and aging brain Neurobiol. Dis. 20 2005 858 870
51. T.G. Beach, R. Walker, and E.G. McGeer Patterns of gliosis in Alzheimer's disease and aging cerebrum Glia 2 1989 420 436
52. S. Futakawa, K. Nara, M. Miyajima, A. Kuno, H. Ito, H. Kaji, K. Shirotani, T. Honda, Y. Tohyama, K. Hoshi, Y. Hanzawa, S. Kitazume, R. Imamaki, K. Furukawa, K. Tasaki, H. Arai, T. Yuasa, M. Abe, H. Arai, H. Narimatsu, and Y. Hashimoto A unique N-glycan on human transferrin in CSF: a possible biomarker for iNPH Neurobiol. Aging 33 2012 1807 1815
53. N. Itoh, S. Sakaue, H. Nakagawa, M. Kurogochi, H. Ohira, K. Deguchi, S. Nishimura, and M. Nishimura Analysis of N-glycan in serum glycoproteins from db/db mice and humans with type 2 diabetes Am. J. Physiol. Endocrinol. Metab. 293 2007 E1069 E1077
54. D.E. McMillan Elevation of glycoprotein fucose in diabetes mellitus Diabetes 21 1972 863 871
55. L.P. Lee, A. Prasad, K.J. Bolton, J.B. McKendry, and I. Hynie Serum UDP-galactose: glycoprotein galactosyltransferase in diabetics with microangiopathy Clin. Biochem. 10 1977 111 117
56. J. Walston, M.A. McBurnie, A. Newman, R.P. Tracy, W.J. Kop, C.H. Hirsch, J. Gottdiener, L.P. Fried, and S. Cardiovascular Health Frailty and activation of the inflammation and coagulation systems with and without clinical comorbidities: results from the Cardiovascular Health Study Arch. Intern. Med. 162 2002 2333 2341
57. J. Walston, E.C. Hadley, L. Ferrucci, J.M. Guralnik, A.B. Newman, S.A. Studenski, W.B. Ershler, T. Harris, and L.P. Fried Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults J. Am. Geriatr. Soc. 54 2006 991 1001
58. K. Darvin, A. Randolph, S. Ovalles, D. Halade, L. Breeding, A. Richardson, and S.E. Espinoza Plasma protein biomarkers of the geriatric syndrome of frailty J. Gerontol. A Biol. Sci. Med. Sci. 69 2014 182 186
59. E. Quentin, A. Gladen, L. Roden, and H. Kresse A genetic defect in the biosynthesis of dermatan sulfate proteoglycan: galactosyltransferase I deficiency in fibroblasts from a patient with a progeroid syndrome Proc. Natl. Acad. Sci. U. S. A. 87 1990 1342 1346
60. T. Okajima, S. Fukumoto, K. Furukawa, and T. Urano Molecular basis for the progeroid variant of Ehlers-Danlos syndrome. Identification and characterization of two mutations in galactosyltransferase I gene J. Biol. Chem. 274 1999 28841 28844
61. V. Borelli, V. Vanhooren, E. Lonardi, K.R. Reiding, M. Capri, C. Libert, P. Garagnani, S. Salvioli, C. Franceschi, and M. Wuhrer Plasma N-glycome signature of down syndrome J. Proteome Res. 14 2015 4232 4245
62. R. Parekh, I. Roitt, D. Isenberg, R. Dwek, and T. Rademacher Age-related galactosylation of the N-linked oligosaccharides of human serum IgG J. Exp. Med. 167 1988 1731 1736
63. N. Tsuchiya, T. Endo, K. Matsuta, S. Yoshinoya, F. Takeuchi, Y. Nagano, M. Shiota, K. Furukawa, N. Kochibe, K. Ito, and et al. Detection of glycosylation abnormality in rheumatoid IgG using N-acetylglucosamine-specific Psathyrella velutina lectin J. Immunol. 151 1993 1137 1146
64. K. Shikata, T. Yasuda, F. Takeuchi, T. Konishi, M. Nakata, and T. Mizuochi Structural changes in the oligosaccharide moiety of human IgG with aging Glycoconj. J. 15 1998 683 689
65. E. Yamada, Y. Tsukamoto, R. Sasaki, K. Yagyu, and N. Takahashi Structural changes of immunoglobulin G oligosaccharides with age in healthy human serum Glycoconj. J. 14 1997 401 405
66. M.P. Bakovic, M.H. Selman, M. Hoffmann, I. Rudan, H. Campbell, A.M. Deelder, G. Lauc, and M. Wuhrer High-throughput IgG Fc N-glycosylation profiling by mass spectrometry of glycopeptides J. Proteome Res. 12 2013 821 831
67. L.R. Ruhaak, C.A. Koeleman, H.W. Uh, J.C. Stam, D. van Heemst, A.B. Maier, J.J. Houwing-Duistermaat, P.J. Hensbergen, P.E. Slagboom, A.M. Deelder, and M. Wuhrer Targeted biomarker discovery by high throughput glycosylation profiling of human plasma alpha1-antitrypsin and immunoglobulin A PLoS One 8 2013 e73082
68. V. Vanhooren, W. Laroy, C. Libert, and C. Chen N-glycan profiling in the study of human aging Biogerontology 9 2008 351 356
69. V. Vanhooren, X.E. Liu, C. Franceschi, C.F. Gao, C. Libert, R. Contreras, and C. Chen N-glycan profiles as tools in diagnosis of hepatocellular carcinoma and prediction of healthy human ageing Mech. Ageing Dev. 130 2009 92 97
70. J.P. Lu, A. Knezevic, Y.X. Wang, I. Rudan, H. Campbell, Z.K. Zou, J. Lan, Q.X. Lai, J.J. Wu, Y. He, M.S. Song, L. Zhang, G. Lauc, and W. Wang Screening novel biomarkers for metabolic syndrome by profiling human plasma N-glycans in Chinese Han and Croatian populations J. Proteome Res. 10 2011 4959 4969
71. G. Lauc, A. Essafi, J.E. Huffman, C. Hayward, A. Knezevic, J.J. Kattla, O. Polasek, O. Gornik, V. Vitart, J.L. Abrahams, M. Pucic, M. Novokmet, I. Redzic, S. Campbell, S.H. Wild, F. Borovecki, W. Wang, I. Kolcic, L. Zgaga, U. Gyllensten, J.F. Wilson, A.F. Wright, N.D. Hastie, H. Campbell, P.M. Rudd, and I. Rudan Genomics meets glycomics-the first GWAS study of human N-glycome identifies HNF1alpha as a master regulator of plasma protein fucosylation PLoS Genet. 6 2010 e1001256
72. J.E. Huffman, A. Knezevic, V. Vitart, J. Kattla, B. Adamczyk, M. Novokmet, W. Igl, M. Pucic, L. Zgaga, A. Johannson, I. Redzic, O. Gornik, T. Zemunik, O. Polasek, I. Kolcic, M. Pehlic, C.A. Koeleman, S. Campbell, S.H. Wild, N.D. Hastie, H. Campbell, U. Gyllensten, M. Wuhrer, J.F. Wilson, C. Hayward, I. Rudan, P.M. Rudd, A.F. Wright, and G. Lauc Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults Hum. Mol. Genet. 20 2011 5000 5011
73. K. Shimizu, N. Hirose, Y. Ebihara, Y. Arai, M. Hamamatsu, S. Nakazawa, Y. Masui, H. Inagaki, Y. Gondo, J. Fujimori, Y. Kanno, K. Konishi, and K. Kitagawa Blood type B might imply longevity Exp. Gerontol. 39 2004 1563 1565
74. C. Lopez-Otin, M.A. Blasco, L. Partridge, M. Serrano, and G. Kroemer The hallmarks of aging Cell 153 2013 1194 1217
75. P. Sebastiani, N. Solovieff, A.T. Dewan, K.M. Walsh, A. Puca, S.W. Hartley, E. Melista, S. Andersen, D.A. Dworkis, J.B. Wilk, R.H. Myers, M.H. Steinberg, M. Montano, C.T. Baldwin, J. Hoh, and T.T. Perls Genetic signatures of exceptional longevity in humans PLoS One 7 2012 e29848
76. H.J. Gierman, K. Fortney, J.C. Roach, N.S. Coles, H. Li, G. Glusman, G.J. Markov, J.D. Smith, L. Hood, L.S. Coles, and S.K. Kim Whole-genome sequencing of the world's oldest people PLoS One 9 2014 e112430
77. G.W. Hart, M.P. Housley, and C. Slawson Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteins Nature 446 2007 1017 1022
78. P. Cheung, J. Pawling, E.A. Partridge, B. Sukhu, M. Grynpas, and J.W. Dennis Metabolic homeostasis and tissue renewal are dependent on beta1,6GlcNAc-branched N-glycans Glycobiology 17 2007 828 837
79. K. Ohtsubo, S. Takamatsu, M.T. Minowa, A. Yoshida, M. Takeuchi, and J.D. Marth Dietary and genetic control of glucose transporter 2 glycosylation promotes insulin secretion in suppressing diabetes Cell 123 2005 1307 1321