Expanded Hematopoietic Progenitor Cells Reselected for High Aldehyde Dehydrogenase Activity Demonstrate Islet Regenerative Functions

Stem Cells

Volumn 34, Issue 4, 2016, Pages 873-887

  Seneviratne, Ayesh K ^a,b   Bell, Gillian I ^a,b   Sherman, Stephen E ^a,b   Cooper, Tyler T ^a,b   Putman, David M ^a,b   Hess, David A ^a,b  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b WESTERN UNIVERSITY   (Canada)

Author keywords

Aldehyde dehydrogenase; Diabetes; Hematopoietic progenitor cells; Islet regeneration; Transplantation; Umbilical cord blood

Indexed keywords

ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE 1 A1; ANGIOPOIETIN 2; CD133 ANTIGEN; CD31 ANTIGEN; CD33 ANTIGEN; CD34 ANTIGEN; CD38 ANTIGEN; CHF PROTEIN; CHORDIN LIKE PROTEIN 1; CRHBP PROTEIN; CYTOKINE RECEPTOR; CYTOKINE RECEPTOR LIKE FACTOR 2; FIBRILLIN 1; FREM1 PROTEIN; GLUCOSE; HPDGS PROTEIN; INSULIN; INTERCELLULAR ADHESION MOLECULE 3; INTERLEUKIN 1 RECEPTOR TYPE I; ITAG9 PROTEIN; L SELECTIN; LACTADHERIN; MESSENGER RNA; PEROXIDASIN; PROMININ 1; PROTEIN; SEMAPHORIN; SEMAPHORIN 4A; TIE RECEPTOR; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPILLARY DENSITY; CELL ADHESION; CELL COUNT; CELL DIFFERENTIATION; CELL FUNCTION; CELL LOSS; CELL MATURATION; CELL POPULATION; CELL PROLIFERATION; CELL REGENERATION; CELL SELECTION; CELL SIZE; CELL STIMULATION; CELL SURFACE; COLONY FORMING UNIT; CONTROLLED STUDY; DISEASE SEVERITY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PURIFICATION; ERYTHROBLAST; EX VIVO STUDY; GENETIC TRANSCRIPTION; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; GLYCEMIC CONTROL; GRANULOCYTE; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERGLYCEMIA; IN VITRO STUDY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PANCREAS FUNCTION; PANCREAS ISLET BETA CELL; PANCREAS ISLET REGENERATION; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RNA TRANSCRIPTION; SIGNAL TRANSDUCTION; STEM CELL EXPANSION; TISSUE REGENERATION; UMBILICAL CORD BLOOD; UPREGULATION; ANIMAL; BIOLOGICAL THERAPY; BIOSYNTHESIS; CELL SEPARATION; CORD BLOOD STEM CELL TRANSPLANTATION; CYTOLOGY; DIABETES MELLITUS, EXPERIMENTAL; FETUS BLOOD; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PANCREAS ISLET; PATHOLOGY; REGENERATION;

ALDEHYDE DEHYDROGENASE; ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SEPARATION; CELL- AND TISSUE-BASED THERAPY; CORD BLOOD STEM CELL TRANSPLANTATION; DIABETES MELLITUS, EXPERIMENTAL; FETAL BLOOD; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HUMANS; ISLETS OF LANGERHANS; MICE; REGENERATION;

EID: 84955575785     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2268     Document Type: Article

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