Cocultivation of umbilical cord blood cells with endothelial cells leads to extensive amplification of competent CD34+CD38- cells

Experimental Hematology

Volumn 28, Issue 7, 2000, Pages 841-852

  Rosler, Elen ^a   Brandt, John ^a   Chute, John ^b   Hoffman, Ronald ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

^b NAVAL MEDICAL RESEARCH INSTITUTE   (United States)

Author keywords

Cord blood; Cytokines; Endothelial cells; Stem cell expansion

Indexed keywords

CD34 ANTIGEN; CD38 ANTIGEN; CYTOKINE; FLT3 LIGAND; FLUORESCENT DYE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; RECOMBINANT INTERLEUKIN 3; RECOMBINANT INTERLEUKIN 6; RECOMBINANT MEGAKARYOCYTE GROWTH AND DEVELOPMENT FACTOR; RECOMBINANT NERVE GROWTH FACTOR; RECOMBINANT STEM CELL FACTOR; STEM CELL FACTOR;

ANIMAL CELL; ARTICLE; BLOOD CELL; CELL PROLIFERATION; COCULTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; MONOLAYER CULTURE; NONHUMAN; PRIORITY JOURNAL; STEM CELL; STROMA CELL; TRANSPLANTATION; UMBILICAL CORD BLOOD;

SUIDAE;

EID: 0034089743     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-472X(00)00177-6     Document Type: Article

References (64)

1. Wagner J.E., Kernan N.A., Steinbuch M., Broxmeyer H.E., Gluckman E. Allogeneic sibling umbilical cord transplantation in forty-four children with malignant and non-malignant disease. Lancet. 346:1995;214.
2. Kurtzberg J., Laughlin M., Graham M.L.et al. Placental blood as a source of hematopoietic stem cells for transplantation into unrelated recipients. N Engl J Med. 335:1996;157.
3. Wagner J.E., Rosenthal J., Sweetman R.et al. Successful transplantation of HLA-matched and HLA-mismatched umbilical cord blood from unrelated donors. analysis of engraftment and acute graft-versus-host disease Blood. 88:1996;795.
4. Gluckman E., Rocha V., Chammard A.et al. Outcome of cord blood transplantation from related and unrelated donors. Eurocord Transplant Group and the European Blood and Marrow Transplantation group. N Engl J Med. 337:1997;373.
5. Rubinstein P., Carrier C., Scaradavou A.et al. Outcomes among 562 recipients of placental blood transplants from unrelated donor. N Engl J Med. 339:1998;1565.
6. Locatelli F., Rocha V., Chastang C.et al. Factors associated with outcome after cord blood transplantation in children with acute leukemia. Blood. 93:1999;3662.
7. Cairo M.S., Wagner J.E. Placental and/or umbilical cord blood. an alternate source of hematopoietic stem cells for transplantation Blood. 90:1997;465.
8. Broxmeyer H.E., Hangoc G., Cooper S.et al. Growth characteristics and expansion of human umbilical cord blood and estimation of its potential for transplantation in adults. Proc Natl Acad Sci USA. 89:1992;4109.
9. Uchida N., Aguilla H., Fleming W.H., Jerabek L., Weissman I.L. Rapid and sustained hematopoietic recovery of lethally irradiated mice transplanted with purified hematopoietic stem cells. Blood. 83:1994;3758.
10. Zijlmans J.M., Visser J.W., Kleiverda K., Kluin P.M., Willemze R., Fibbe W.E. Modification of rhodamine staining allows identification of hematopoietic stem cells with preferential short-term or long-term bone marrow-repopulating ability. Proc Natl Acad USA. 92:1995;6901.
11. Zijlmans J.M., Visser J.W., Laterveer L.et al. The early phase of engraftment after murine blood cell transplantation is mediated by hematopoietic stem cells. Proc Natl Acad Sci USA. 95:1998;725.
12. Tricot G., Gazitt Y., Leemhuis T.et al. Collection, tumor contamination, engraftment kinetics of highly purified hematopoietic progenitor cells to support high dose therapy in multiple myeloma. Blood. 91:1998;4489.
13. Hows J.M., Bradley B.A., Marsh J.C.W.et al. Growth of umbilical cord blood in long-term haemopoietic cultures. Lancet. 340:1992;73.
14. + cord blood cells in serum-free long-term cultures supplemented with hematopoietic cytokines. Blood. 82:1993;2664.
15. + cells from human bone marrow, peripheral blood and cord blood. Blood Cells. 20:1994;411.
16. Vormoor J., Lapidot T., Pflumio F.et al. Immature human cord blood progenitors engraft and proliferate to high levels in severe combined immunodeficient mice. Blood. 83:1994;2489.
17. Traycoff C.M., Kosak S.T., Grigsby S., Srour E.F. Evaluation of ex vivo expansion potential of cord blood and bone marrow hematopoietic progenitor cells using cell tracking and limiting dilution analysis. Blood. 85:1995;2059.
18. Piacibello W., Sanavio F., Garetto L.et al. Extensive amplification and self-renewal of human primitive hematopoietic stem cells from cord blood. Blood. 89:1997;2644.
19. Lowry P.A., Shultz L.D., Greiner D.L.et al. Improved engraftment of human cord blood stem cells in NOD/LtSz-scid/scid mice after irradiation or multiple-day injections into unirradiated recipients. Blood and Marrow Transplant. 2:1996;15.
20. DiGiusto D.L., Lee R., Moon J.et al. Hematopoietic potential of cryopreserved and ex vivo manipulated umbilical cord blood progenitor cells evaluated in vitro and in vivo. Blood. 87:1996;1261.
21. + progenitors to sustain long-term hematopoiesis in immune-deficient mice after ex vivo retroviral-mediated transduction. Blood. 89:1997;446.
22. Gan O.I., Murdoch B., Larochelle A., Dick J.E. Differential maintenance of primitive human SCID-repopulating cells, clonogenic progenitors, and long-term culture-initiating cells after incubation on human bone marrow stromal cells. Blood. 90:1997;641.
23. Conneally E., Cashman J., Petzer A., Eaves C. Expansion in vitro of transplantable human cord blood stem cells demonstrated using a quantitative assay of their lympho-myeloid repopulating activity in nonobese diabetic-scid/scid mice. Proc Natl Acad Sci USA. 94:1997;9836.
24. +-enriched cells from umbilical cord blood in NOD/LtSz-scid/scid mice. Blood. 90:1997;85.
25. Larochelle A., Vormoor J., Hanenberg H.et al. Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow. Implications for gene therapy Nat Med. 2:1996;1329.
26. Bhatia M., Wang J.C.Y., Kapp U., Bonnet D., Dick J.E. Purification of primitive human hematopoietic cells capable of repopulating immunedeficient mice. Proc Natl Acad Sci USA. 94:1997;5320.
27. Cashman J., Bockhold K., Hogge D.E., Eaves A.C., Eaves C.J. Sustained proliferation, multi-lineage differentiation and maintenance of primitive human hemopoietic cells in NOD/SCID mice transplanted with human cord blood. Br J Haematol. 97:1997;1026.
28. Spence S.E., Keller J.R., Ruscetti F.W.et al. Engraftment of ex vivo expanded and cycling human cord blood hematopoietic progenitor cells in SCID mice. Exp Hematol. 26:1997;507.
29. Xu M.J., Tsuji K., Ueda T.et al. Stimulation of mouse and human primitive hematopoiesis by murine embryonic aorta-gonad-mesonephros-derived stromal cell lines. Blood. 92:1998;2032.
30. + cell decline and ex vivo expansion capacity Br J Haematol. 104:1999;178.
31. --/low cells capable of repopulating severe combined immunodeficiency mice. Blood. 94:1999;923.
32. Köhler T., Plettig R., Wetzstein W.et al. Defining optimum conditions for the ex vivo expansion of human umbilical cord blood cells, influences of progenitor enrichment, interference with feeder layers, early-acting cytokines and agitation of culture vessels. Stem cells. 17:1999;19.
33. Knäan-Shanzer S., Verlinden S.F.F., van Beusechem V.W., Van Bekkum D.W., Valerio D. Intrinsic potential of phenotypically defined human hemopoietic stem cells to self-renew in short-term in vitro cultures. Exp Hematol. 27:1999;1440.
34. + cord blood cells. Blood. 93:1999;1097.
35. Kawada H., Ando K., Tsuju T.et al. Rapid ex vivo expansion of human umbilical cord hematopoietic progenitors using a novel culture system. Exp Hematol. 27:1999;904.
36. + cord blood cells after ex vivo expansion. Evidence for the amplification and self-renewal of repopulating stem cells Blood. 93:1999;3736.
37. + cells. Blood. 94:1999;3269.
38. + cells expands progenitor cell numbers, preserves engraftment capacity in nonobese diabetic/severe combined immunodeficient mice, and enhances retrovitral transduction efficiency. Hum Gene Ther. 10:1999;2927.
39. Crisa L., Cirulli V., Smith K.A., Ellisman M.H., Torbet B.E., Salomon D.R. Human cord blood progenitors sustain thymic T-cell development and a novel form of angiogenesis. Blood. 94:1999;3928.
40. van Hennik P.B., de Koning A.E., Ploemacher R.E. Seeding efficiency of primitive human hematopoietic cells in nonobese diabetic/severe combined immune deficiency mice. Implications for stem cell frequency assessment Blood. 94:1999;3055.
41. Holyoake T.L., Nicolini F.E., Eaves C.J. Functional differences between transplantable human hematopoietic stem cells from fetal liver, cord blood, and adult marrow. Exp Hematol. 27:1999;1418.
42. Bhatia M., Bonnet D., Kapp U., Wang J.C.Y., Murdoch B., Dick J.E. Quantitative analysis reveals expansion of human hematopoietic repopulating cells after short-term ex vivo culture. J Exp Med. 186:1997;619.
43. Davis T.A., Robinson D.H., Lee K.P., Kessler S.W. Porcine brain microvascular endothelial cells support the in vitro expansion of human primitive hematopoietic bone marrow progenitor cells with a high replating potential. Requirement for cell-to-cell interactions and colony-stimulating factors Blood. 85:1995;1751.
44. Brandt J.E., Galy A.H.M., Luens K.M.et al. Bone marrow repopulation by human marrow stem cells following long-term expansion culture on a porcine endothelial cell line. Exp Hematol. 26:1998;950.
45. + cells with porcine microvascular endothelial cells results in a graft capable of rescuing lethally irradiated baboons. Blood. 94:1999;106.
46. Yonemura Y., Ku H., Hirayama F., Souza L.M., Ogawa M. Interleukin-3 or interleukin-1 abrogates the reconstitution ability of hematopoietic stem cells. Proc Natl Acad Sci USA. 93:1996;4040.
47. Habibian H.K., Peters S.O., Hsieh C.C.et al. The fluctuating phenotype of lymphohematopoietic stem cell with cell cycle transit. J Exp Med. 133:1998;393.
48. Fraser C.C., Kaneshima H., Hansteen G., Kilpatrick M., Hoffman R., Chen B.P. Human allogeneic stem cell maintenance and differentiation in a long-term multilineage SCID-hu graft. Blood. 86:1995;1680.
49. Kyoizumi S., Baum C.M., Kaneshima H., McCune J.M., Yee E.J., Namikawa R. Implantation and maintenance of functional human bone marrow in SCID-hu mice. Blood. 79:1992;1704.
50. Van der Loo J.C.M., Ploemacher R.E. Marrow- and spleen-seeding efficiencies of all murine hematopoietic stem cell subsets are decreased by preincubation with hematopoietic growth factors. Blood. 85:1995;2598.
51. Peters S.O., Kittler E.L.W., Ramshaw H.S., Quesenberry P.J. Murine marrow cells expanded in culture with IL-3, IL-6, IL-11, and SCF acquire an engraftment defect in normal hosts. Exp Hematol. 23:1995;461.
52. Peters S.O., Kittler E.L.W., Ramshaw H.S., Quesenberry P.J. Ex vivo expansion of murine marrow cells with interleukin-3 (IL-3), IL-6, IL-11, and stem cell factor leads to impaired engraftment in irradiated hosts. Blood. 87:1996;30.
53. Harrison D.E., Astle C.M. Loss of stem cell repopulating ability upon transplantation. J Exp Med. 156:1982;1767.
54. Harrison D.E., Stone M., Astle C.M. Effects of transplantation on the primitive immunohematopoietic stem cell. J Exp Med. 172:1990;421.
55. Shpall E.J., Quinones R., Jones R.et al. Transplantation of adult and pediatric cancer patients with cord blood progenitors expanded ex vivo. Blood. 94(Suppl 1):1999;712a.
56. Stiff P., Pecora P., Parthasarthy M.et al. Umbilical cord blood transplants using a combination of unexpanded and expanded cells. Preliminary clinical observations Blood. 92(Suppl 1):1998;646a.
57. - human hematopoietic progenitors from fetal liver, cord blood, and adult bone marrow respond differently to hematopoietic cytokines depending on the ontogenic source. Exp Hematol. 26:1998;1034.
58. Zandstra P.W., Conneally E., Piret J.M., Eaves C.J. Ontogeny-associated changes in the cytokine responses of primitive human haemopoietic cells. Br J Haematol. 101:1998;770.
59. Spangrude G.J., Brooks D.M., Tumas D.B. Long-term repopulation of irradiated mice with limiting numbers of purified hematopoietic stem cells. In vivo expansion of stem cell phenotype but not function Blood. 85:1995;1006.
60. Lansdorp P.M., Dragowska W., Mayani H. Ontogeny-related changes in the proliferative potential of human hematopoietic cells. J Exp Med. 178:1993;787.
61. +++ human umbilical cord blood hematopoietic progenitors with high proliferative and replating potential. Blood. 81:1993;41.
62. Pettengell R., Luft T., Henschler R.et al. Direct comparison by limiting dilution analysis of long term culture-initiating cells in human bone marrow, umbilical cord blood and blood stem cells. Blood. 84:1994;3653.
63. Shizuru J.A., Jerabek L., Edwards C.T., Weissman I.L. Transplantation of purified hematopoietic stem cells. Requirements for overcoming the barriers of allogeneic engraftment Biol Blood Marrow Transplant. 2:1996;3.
64. - hematopoietic cells. Exp Hematol. 27(Suppl 1):1999;41.