Islet versus pancreas transplantation in type 1 diabetes: Competitive or complementary?

Current Diabetes Reports

Volumn 10, Issue 6, 2010, Pages 506-511

  Ludwig, Barbara ^a,b   Ludwig, Stefan ^a   Steffen, Anja ^a,b   Saeger, Hans Detlev ^a,b   Bornstein, Stefan R ^a,b  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Diabetes; Indication; Islet; Pancreas; Transplantation

Indexed keywords

CLINICAL DECISION MAKING; CLINICAL TRIAL; DIABETIC RETINOPATHY; GLUCOSE HOMEOSTASIS; GLYCEMIC CONTROL; GRAFT SURVIVAL; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; INTERMETHOD COMPARISON; KIDNEY FAILURE; KIDNEY PANCREAS TRANSPLANTATION; OUTCOME ASSESSMENT; PANCREAS ISLET TRANSPLANTATION; PATIENT SAFETY; REVIEW; SURGICAL APPROACH; SURVIVAL RATE; TREATMENT INDICATION; TREATMENT PLANNING;

DIABETES MELLITUS, TYPE 1; HUMANS; ISLETS OF LANGERHANS TRANSPLANTATION; PANCREAS TRANSPLANTATION;

EID: 77958502506     PISSN: 15344827     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11892-010-0146-y     Document Type: Review

References (33)

1. MW Steffes S Sibley M Jackson W Thomas 2003 Beta-cell function and the development of diabetes-related complications in the diabetes control and complications trial Diabetes Care 26 832 836 10.2337/diacare.26.3.832 12610045 (Pubitemid 36929351)
2. WD Kelly RC Lillehei FK Merkel, et al. 1967 Allotransplantation of the pancreas and duodenum along with the kidney in diabetic nephropathy Surgery 61 827 837 1:STN:280:DyaF2s7msFSisQ%3D%3D 5338113
3. AC Gruessner DE Sutherland 2005 Pancreas transplant outcomes for United States (US) and non-US cases as reported to the United Network for Organ Sharing (UNOS) and the International Pancreas Transplant Registry (IPTR) as of June 2004 Clin Transplant 19 433 455 10.1111/j.1399-0012.2005.00378.x 16008587 (Pubitemid 40990653)
4. JM Venstrom MA McBride KI Rother, et al. 2003 Survival after pancreas transplantation in patients with diabetes and preserved kidney function JAMA 290 2817 2823 1:CAS:528:DC%2BD3sXps1Cru7w%3D 10.1001/jama.290.21.2817 14657065 (Pubitemid 37509489)
5. WF Ballinger PE Lacy 1972 Transplantation of intact pancreatic islets in rats Surgery 72 175 186 1:STN:280:DyaE383ls1Ohsw%3D%3D 4262169
6. AM Shapiro JR Lakey EA Ryan, et al. 2000 Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen N Engl J Med 343 230 238 1:CAS:528: DC%2BD3cXlvVSmt7k%3D 10.1056/NEJM200007273430401 10911004 (Pubitemid 30490390)
7. AO Ojo HU Meier-Kriesche JA Hanson, et al. 2001 The impact of simultaneous pancreas-kidney transplantation on long-term patient survival Transplantation 71 82 90 1:STN:280:DC%2BD3M7jsVKhsQ%3D%3D 10.1097/00007890- 200101150-00014 11211201
8. P Robertson C Davis J Larsen, et al. 2004 Pancreas transplantation in type 1 diabetes Diabetes Care 27 Suppl 1 S105 14693941
9. • Sollinger HW, Odorico JS, Becker YT, et al.: One thousand simultaneous pancreas-kidney transplants at a single center with 22-year follow-up. Ann Surg 2009, Aug 27 [Epub ahead of print]. This paper shows the largest cohort of SPK transplants at a single center ever with the longest follow-up period of more than 20 years. This is an impressive report by Dr. Sollinger, one of the true pioneers in pancreas transplantation, sharing his tremendous experience in the pancreas transplant field.
10. P Fioretto MW Steffes DE Sutherland, et al. 1998 Reversal of lesions of diabetic nephropathy after pancreas transplantation N Engl J Med 339 69 75 1:STN:280:DyaK1czgslKhsA%3D%3D 10.1056/NEJM199807093390202 9654536 (Pubitemid 28304880)
11. A Coppelli R Giannarelli F Vistoli, et al. 2005 The beneficial effects of pancreas transplant alone on diabetic nephropathy Diabetes Care 28 1366 1370 10.2337/diacare.28.6.1366 15920053 (Pubitemid 40756698)
12. R Giannarelli A Coppelli M Sartini, et al. 2005 Effects of pancreas-kidney transplantation on diabetic retinopathy Transpl Int 18 619 622 10.1111/j.1432-2277.2005.00108.x 15819813 (Pubitemid 41726867)
13. R Koznarova F Saudek T Sosna, et al. 2000 Beneficial effect of pancreas and kidney transplantation on advanced diabetic retinopathy Cell Transplant 9 903 908 1:STN:280:DC%2BD3M7nsl2qtw%3D%3D 11202576
14. AO Gaber D Oxley J Karas, et al. 1991 Changes in gastric emptying in recipients of successful combined pancreas-kidney transplants Dig Dis 9 437 443 1:STN:280:DyaK383gvFWgsg%3D%3D 10.1159/000171334 1804583
15. DK Hathaway T Abell S Cardoso, et al. 1994 Improvement in autonomic and gastric function following pancreas-kidney versus kidney-alone transplantation and the correlation with quality of life Transplantation 57 816 822 1:STN:280:DyaK2c3gsFSqsg%3D%3D 10.1097/00007890-199403270-00008 8154027 (Pubitemid 24114670)
16. BA Perkins V Bril 2002 Diagnosis and management of diabetic neuropathy Curr Diab Rep 2 495 500 10.1007/s11892-002-0119-x 12643156
17. C Morath M Zeier B Dohler, et al. 2008 Metabolic control improves long-term renal allograft and patient survival in type 1 diabetes J Am Soc Nephrol 19 1557 1563 10.1681/ASN.2007070804 18495965
18. A Coppelli R Giannarelli R Mariotti, et al. 2003 Pancreas transplant alone determines early improvement of cardiovascular risk factors and cardiac function in type 1 diabetic patients Transplantation 76 974 976 10.1097/01.TP.0000084202.18999.1D 14508364 (Pubitemid 37186030)
19. P Fiorina E La Rocca E Astorri, et al. 2000 Reversal of left ventricular diastolic dysfunction after kidney-pancreas transplantation in type 1 diabetic uremic patients Diabetes Care 23 1804 1810 1:STN:280:DC%2BD3M7hsVajug%3D%3D 10.2337/diacare.23.12.1804 11128357
20. P Fiorina E La Rocca M Venturini, et al. 2001 Effects of kidney-pancreas transplantation on atherosclerotic risk factors and endothelial function in patients with uremia and type 1 diabetes Diabetes 50 496 501 1:CAS:528:DC%2BD3MXhslGhur8%3D 10.2337/diabetes.50.3.496 11246868
21. JW Jukema YF Smets JW van der Pijl, et al. 2002 Impact of simultaneous pancreas and kidney transplantation on progression of coronary atherosclerosis in patients with end-stage renal failure due to type 1 diabetes Diabetes Care 25 906 911 10.2337/diacare.25.5.906 11978689 (Pubitemid 41094291)
22. JL Larsen CW Colling T Ratanasuwan, et al. 2004 Pancreas transplantation improves vascular disease in patients with type 1 diabetes Diabetes Care 27 1706 1711 10.2337/diacare.27.7.1706 15220250 (Pubitemid 38857448)
23. JL Larsen T Ratanasuwan T Burkman, et al. 2002 Carotid intima media thickness decreases after pancreas transplantation Transplantation 73 936 940 10.1097/00007890-200203270-00019 11923696
24. FL Luan CD Miles DM Cibrik AO Ojo 2007 Impact of simultaneous pancreas and kidney transplantation on cardiovascular risk factors in patients with type 1 diabetes mellitus Transplantation 84 541 544 10.1097/01.tp.0000270617.43811.af 17713440 (Pubitemid 47312167)
25. EA Ryan BW Paty PA Senior, et al. 2005 Five-year follow-up after clinical islet transplantation Diabetes 54 2060 2069 1:CAS:528:DC%2BD2MXmtVelsbs%3D 10.2337/diabetes.54.7.2060 15983207 (Pubitemid 40911269)
26. CB Leitao T Tharavanij P Cure, et al. 2008 Restoration of hypoglycemia awareness after islet transplantation Diabetes Care 31 2113 2115 10.2337/dc08-0741 18697903
27. MR Rickels MH Schutta JF Markmann, et al. 2005 {beta}-Cell function following human islet transplantation for type 1 diabetes Diabetes 54 100 106 1:CAS:528:DC%2BD2MXhtVWju78%3D 10.2337/diabetes.54.1.100 15616016 (Pubitemid 40105100)
28. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group [no authors listed]. N Engl J Med 1993, 329:977-986.
29. HC Gerstein ME Miller RP Byington, et al. 2008 Effects of intensive glucose lowering in type 2 diabetes N Engl J Med 358 2545 2559 1:CAS:528:DC%2BD1cXnt1Wjs7s%3D 10.1056/NEJMoa0802743 18539917 This is a highly controversial large multicenter study (ACCORD) that investigated the effect of intensive insulin therapy on cardiovascular events in type 2 diabetes patients. The initial conclusion of increased risk by rigorous glucose lowering provoked the whole diabetes world. (Pubitemid 351831356)
30. P Fiorina C Gremizzi P Maffi, et al. 2005 Islet transplantation is associated with an improvement of cardiovascular function in type 1 diabetic kidney transplant patients Diabetes Care 28 1358 1365 10.2337/diacare.28.6.1358 15920052 (Pubitemid 40756697)
31. P Fiorina F Folli G Zerbini, et al. 2003 Islet transplantation is associated with improvement of renal function among uremic patients with type I diabetes mellitus and kidney transplants J Am Soc Nephrol 14 2150 2158 10.1097/01.ASN.0000077339.20759.A3 12874470 (Pubitemid 36909924)
32. TC Lee NR Barshes CA O'Mahony, et al. 2005 The effect of pancreatic islet transplantation on progression of diabetic retinopathy and neuropathy Transplant Proc 37 2263 2265 1:STN:280:DC%2BD2MzhslWmsA%3D%3D 10.1016/j.transproceed.2005.03.011 15964394 (Pubitemid 40956427)
33. AM de Mattos AJ Olyaei WM Bennett 2000 Nephrotoxicity of immunosuppressive drugs: long-term consequences and challenges for the future Am J Kidney Dis 35 333 346 10.1016/S0272-6386(00)70253-8 10676738