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Volumn 2016, Issue , 2016, Pages

IPSCs: A Minireview from bench to bed, including organoids and the crispr system

Author keywords

[No Author keywords available]

Indexed keywords

KRUPPEL LIKE FACTOR 4; MESSENGER RNA; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; PLASMID VECTOR; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2;

EID: 84955445987     PISSN: None     EISSN: 16879678     Source Type: Journal    
DOI: 10.1155/2016/5934782     Document Type: Review
Times cited : (18)

References (68)
  • 1
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • J.A. Thomson, J. Itskovitz-Eldor, S. S. Shapiroet al., "Embryonic stem cell lines derived from human blastocysts, " Science, vol. 282, no. 5391, pp. 1145-1147, 1998.
    • (1998) Science , vol.282 , Issue.5391 , pp. 1145-1147
    • Thomson, J.A.1    Itskovitz-Eldor, J.2    Shapiro, S.S.3
  • 2
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • L. A. Boyer, T. I. Lee, M. F. Cole et al., "Core transcriptional regulatory circuitry in human embryonic stem cells, " Cell, vol. 122, no. 6, pp. 947-956, 2005.
    • (2005) Cell , vol.122 , Issue.6 , pp. 947-956
    • Boyer, L.A.1    Lee, T.I.2    Cole, M.F.3
  • 3
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • K. Takahashi and S. Yamanaka, "Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors, " Cell, vol. 126, no. 4, pp. 663-676, 2006.
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 4
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • K. Takahashi, K. Tanabe, M. Ohnuki et al., "Induction of pluripotent stem cells from adult human fibroblasts by defined factors, " Cell, vol. 131, no. 5, pp. 861-872, 2007.
    • (2007) Cell , vol.131 , Issue.5 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3
  • 5
    • 64249157351 scopus 로고    scopus 로고
    • Epigenetic reprogramming and induced pluripotency
    • K. Hochedlinger and K. Plath, "Epigenetic reprogramming and induced pluripotency, " Development, vol. 136, no. 4, pp. 509-523, 2009.
    • (2009) Development , vol.136 , Issue.4 , pp. 509-523
    • Hochedlinger, K.1    Plath, K.2
  • 6
    • 10744226888 scopus 로고    scopus 로고
    • Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs
    • S. Cawley, S. Bekiranov, H. H. Ng et al., "Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs, " Cell, vol. 116, no. 4, pp. 499-509, 2004.
    • (2004) Cell , vol.116 , Issue.4 , pp. 499-509
    • Cawley, S.1    Bekiranov, S.2    Ng, H.H.3
  • 7
    • 0032493894 scopus 로고    scopus 로고
    • The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins
    • S. B. McMahon, H. A. Van Buskirk, K. A. Dugan, T. D. Copeland, and M. D. Cole, "The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins, " Cell, vol. 94, no. 3, pp. 363-374, 1998.
    • (1998) Cell , vol.94 , Issue.3 , pp. 363-374
    • McMahon, S.B.1    Van Buskirk, H.A.2    Dugan, K.A.3    Copeland, T.D.4    Cole, M.D.5
  • 8
    • 77954895521 scopus 로고    scopus 로고
    • Generation of human-induced pluripotent stem cells from gut mesentery-derived cells by ectopic expression of OCT4/SOX2/NANOG
    • Y. Li, H. Zhao, F. Lan et al., "Generation of human-induced pluripotent stem cells from gut mesentery-derived cells by ectopic expression of OCT4/SOX2/NANOG, " Cellular Reprogramming, vol. 12, no. 3, pp. 237-247, 2010.
    • (2011) Cellular Reprogramming , vol.12 , Issue.3 , pp. 237-247
    • Li, Y.1    Zhao, H.2    Lan, F.3
  • 9
    • 55749104227 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2
    • D. Huangfu, K. Osafune, R. Maehr et al., "Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2, " Nature Biotechnology, vol. 26, no. 11, pp. 1269-1275, 2008.
    • (2008) Nature Biotechnology , vol.26 , Issue.11 , pp. 1269-1275
    • Huangfu, D.1    Osafune, K.2    Maehr, R.3
  • 10
    • 77649275936 scopus 로고    scopus 로고
    • A nonviral minicircle vector for deriving human ips cells
    • F. Jia, K. D. Wilson, N. Sun et al., "A nonviral minicircle vector for deriving human iPS cells, " Nature Methods, vol. 7, no. 3, pp. 197-199, 2010.
    • (2011) Nature Methods , vol.7 , Issue.3 , pp. 197-199
    • Jia, F.1    Wilson, K.D.2    Sun, N.3
  • 11
    • 77949793550 scopus 로고    scopus 로고
    • Reprogramming of human fibroblasts to pluripotent stem cells using mRNA of four transcription factors
    • E. Yakubov, G. Rechavi, S. Rozenblatt, and D. Givol, "Reprogramming of human fibroblasts to pluripotent stem cells using mRNA of four transcription factors, " Biochemical and Biophysical Research Communications, vol. 394, no. 1, pp. 189-193, 2010.
    • (2011) Biochemical and Biophysical Research Communications , vol.394 , Issue.1 , pp. 189-193
    • Yakubov, E.1    Rechavi, G.2    Rozenblatt, S.3    Givol, D.4
  • 12
    • 78650915547 scopus 로고    scopus 로고
    • Generation of iPSCs from mouse fibroblasts with a single gene, oct4, and small molecules
    • Y. Li, Q. Zhang, X. Yin et al., "Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules, " Cell Research, vol. 21, no. 1, pp. 196-204, 2011.
    • (2011) Cell Research , vol.21 , Issue.1 , pp. 196-204
    • Li, Y.1    Zhang, Q.2    Yin, X.3
  • 13
    • 79955572417 scopus 로고    scopus 로고
    • Harnessing the potential of induced pluripotent stem cells for regenerative medicine
    • S. M. Wu and K. Hochedlinger, "Harnessing the potential of induced pluripotent stem cells for regenerative medicine, " Nature Cell Biology, vol. 13, no. 5, pp. 497-505, 2011.
    • (2011) Nature Cell Biology , vol.13 , Issue.5 , pp. 497-505
    • Wu, S.M.1    Hochedlinger, K.2
  • 14
    • 84881256653 scopus 로고    scopus 로고
    • Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds
    • P. Hou, Y. Li, X. Zhang et al., "Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds, " Science, vol. 341, no. 6146, pp. 651-654, 2013.
    • (2013) Science , vol.341 , Issue.6146 , pp. 651-654
    • Hou, P.1    Li, Y.2    Zhang, X.3
  • 15
    • 84932613538 scopus 로고    scopus 로고
    • MEK and TGF-beta inhibition promotes reprogramming without the use of transcription factor
    • Article ID e0127739
    • J. Vrbsky, T. Tereh, S. Kyrylenko, P. Dvorak, L. Krejci, and M. Lako, "MEK and TGF-beta inhibition promotes reprogramming without the use of transcription factor, " PLoS ONE, vol. 10, no. 6, Article ID e0127739, 2015.
    • (2015) PLoS ONE , vol.10 , Issue.6
    • Vrbsky, J.1    Tereh, T.2    Kyrylenko, S.3    Dvorak, P.4    Krejci, L.5    Lako, M.6
  • 16
    • 84885619736 scopus 로고    scopus 로고
    • Deterministic direct reprogramming of somatic cells to pluripotency
    • Y. Rais, A. Zviran, S. Geula et al., "Deterministic direct reprogramming of somatic cells to pluripotency, " Nature, vol. 502, no. 7469, pp. 65-70, 2013.
    • (2013) Nature , vol.502 , Issue.7469 , pp. 65-70
    • Rais, Y.1    Zviran, A.2    Geula, S.3
  • 17
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cell lines derived from human somatic cells
    • J. Yu, M. A. Vodyanik, K. Smuga-Otto et al., "Induced pluripotent stem cell lines derived from human somatic cells, " Science, vol. 318, no. 5858, pp. 1917-1920, 2007.
    • (2007) Science , vol.318 , Issue.5858 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga-Otto, K.3
  • 18
    • 0034136393 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers
    • J. Itskovitz-Eldor, M. Schuldiner, D. Karsenti et al., "Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers, " Molecular Medicine, vol. 6, no. 2, pp. 88-95, 2000.
    • (2000) Molecular Medicine , vol.6 , Issue.2 , pp. 88-95
    • Itskovitz-Eldor, J.1    Schuldiner, M.2    Karsenti, D.3
  • 19
    • 70350605500 scopus 로고    scopus 로고
    • A simple approach for mouse embryonic stem cells isolation and differentiation inducing embryoid body formation
    • C. B. Fagundez, M. A. Loresi, M. E. Ojea Quintana et al., "A simple approach for mouse embryonic stem cells isolation and differentiation inducing embryoid body formation, " Cell Biology International, vol. 33, no. 11, pp. 1196-1200, 2009.
    • (2009) Cell Biology International , vol.33 , Issue.11 , pp. 1196-1200
    • Fagundez, C.B.1    Loresi, M.A.2    Ojea Quintana, M.E.3
  • 20
    • 34249880066 scopus 로고    scopus 로고
    • Generation of germline-competent induced pluripotent stem cells
    • K. Okita, T. Ichisaka, and S. Yamanaka, "Generation of germline-competent induced pluripotent stem cells, " Nature, vol. 448, no. 7151, pp. 313-317, 2007.
    • (2007) Nature , vol.448 , Issue.7151 , pp. 313-317
    • Okita, K.1    Ichisaka, T.2    Yamanaka, S.3
  • 21
    • 67649222358 scopus 로고    scopus 로고
    • Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures
    • M. H. Chin, M. J. Mason, W. Xie et al., "Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures, " Cell Stem Cell, vol. 5, no. 1, pp. 111-123, 2009.
    • (2009) Cell Stem Cell , vol.5 , Issue.1 , pp. 111-123
    • Chin, M.H.1    Mason, M.J.2    Xie, W.3
  • 22
    • 79952264847 scopus 로고    scopus 로고
    • Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
    • R. Lister, M. Pelizzola, Y. S. Kida et al., "Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells, " Nature, vol. 471, no. 7336, pp. 68-73, 2011.
    • (2011) Nature , vol.471 , Issue.7336 , pp. 68-73
    • Lister, R.1    Pelizzola, M.2    Kida, Y.S.3
  • 23
    • 79551677421 scopus 로고    scopus 로고
    • Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines
    • C. Bock, E. Kiskinis, G. Verstappen et al., "Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines, " Cell, vol. 144, no. 3, pp. 439-452, 2011.
    • (2011) Cell , vol.144 , Issue.3 , pp. 439-452
    • Bock, C.1    Kiskinis, E.2    Verstappen, G.3
  • 24
    • 77955449906 scopus 로고    scopus 로고
    • Epigenetic memory in induced pluripotent stem cells
    • K. Kim, A. Doi, B. Wen et al., "Epigenetic memory in induced pluripotent stem cells, " Nature, vol. 467, no. 7313, pp. 285-290, 2010.
    • (2011) Nature , vol.467 , Issue.7313 , pp. 285-290
    • Kim, K.1    Doi, A.2    Wen, B.3
  • 25
    • 84918561297 scopus 로고    scopus 로고
    • Modelling human development and disease in pluripotent stem-cellderived gastric organoids
    • K.W. McCracken, E. M. Cata, C. M. Crawford et al., "Modelling human development and disease in pluripotent stem-cellderived gastric organoids, " Nature, vol. 516, no. 7531, pp. 400-404, 2014.
    • (2014) Nature , vol.516 , Issue.7531 , pp. 400-404
    • McCracken, K.W.1    Cata, E.M.2    Crawford, C.M.3
  • 26
    • 79551686425 scopus 로고    scopus 로고
    • Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro
    • J. R. Spence, C. N. Mayhew, S. A. Rankin et al., "Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro, " Nature, vol. 470, no. 7332, pp. 105-109, 2011.
    • (2011) Nature , vol.470 , Issue.7332 , pp. 105-109
    • Spence, J.R.1    Mayhew, C.N.2    Rankin, S.A.3
  • 27
    • 84930999403 scopus 로고    scopus 로고
    • Interaction of Salmonella enterica serovar typhimurium with intestinal organoids derived fromhuman induced pluripotent stemcells
    • J. L. Forbester, D. Goulding, L. Vallier et al., "Interaction of Salmonella enterica serovar typhimurium with intestinal organoids derived fromhuman induced pluripotent stemcells, " Infection and Immunity, vol. 83, no. 7, pp. 2926-2934, 2015.
    • (2015) Infection and Immunity , vol.83 , Issue.7 , pp. 2926-2934
    • Forbester, J.L.1    Goulding, D.2    Vallier, L.3
  • 28
    • 84925459906 scopus 로고    scopus 로고
    • In vitro generation of human pluripotent stem cell derived lung organoids
    • article 4
    • B. R. Dye, D. R. Hill, M. A. Ferguson et al., "In vitro generation of human pluripotent stem cell derived lung organoids, " Elife, vol. 24, article 4, 2015.
    • (2015) Elife , vol.24
    • Dye, B.R.1    Hill, D.R.2    Ferguson, M.A.3
  • 29
    • 84881184980 scopus 로고    scopus 로고
    • Vascularized and functional human liver from an iPSC-derived organ bud transplant
    • T. Takebe, K. Sekine, M. Enomura et al., "Vascularized and functional human liver from an iPSC-derived organ bud transplant, " Nature, vol. 499, no. 7459, pp. 481-484, 2013.
    • (2013) Nature , vol.499 , Issue.7459 , pp. 481-484
    • Takebe, T.1    Sekine, K.2    Enomura, M.3
  • 30
    • 84884414984 scopus 로고    scopus 로고
    • Cerebral organoidsmodel human brain development and microcephaly
    • M. A. Lancaster, M. Renner, C.-A. Martin et al., "Cerebral organoidsmodel human brain development and microcephaly, " Nature, vol. 501, no. 7467, pp. 373-379, 2013.
    • (2013) Nature , vol.501 , Issue.7467 , pp. 373-379
    • Lancaster, M.A.1    Renner, M.2    Martin, C.-A.3
  • 31
    • 84926039213 scopus 로고    scopus 로고
    • Generation of cerebral organoids fromhuman pluripotent stemcells
    • M. A. Lancaster and J. A. Knoblich, "Generation of cerebral organoids fromhuman pluripotent stemcells, " Nature Protocols, vol. 9, no. 10, pp. 2329-2340, 2014.
    • (2014) Nature Protocols , vol.9 , Issue.10 , pp. 2329-2340
    • Lancaster, M.A.1    Knoblich, J.A.2
  • 32
    • 84883083341 scopus 로고    scopus 로고
    • Repopulation of decellularized mouse heart with human induced pluripotent stemcell-derived cardiovascular progenitor cells nature
    • article 2307
    • T.-Y. Lu, B. Lin, J. Kim et al., "Repopulation of decellularized mouse heart with human induced pluripotent stemcell-derived cardiovascular progenitor cells, "Nature Communications, vol. 4, article 2307, 2013.
    • (2013) Communications , vol.4
    • Lu, T.-Y.1    Lin, B.2    Kim, J.3
  • 33
    • 84863570045 scopus 로고    scopus 로고
    • Bloodderived human iPS cells generate optic vesicle-like structures with the capacity to formretinal laminae and develop synapses
    • M. J. Phillips, K. A. Wallace, S. J. Dickerson et al., "Bloodderived human iPS cells generate optic vesicle-like structures with the capacity to formretinal laminae and develop synapses, " Investigative Ophthalmology &Visual Science, vol. 53, no. 4, pp. 2007-2019, 2012.
    • (2012) Investigative Ophthalmology &Visual Science , vol.53 , Issue.4 , pp. 2007-2019
    • Phillips, M.J.1    Wallace, K.A.2    Dickerson, S.J.3
  • 34
    • 84901439386 scopus 로고    scopus 로고
    • Modeling human retinal development with patient-specific induced pluripotent stem cells reveals multiple roles for visual system homeobox 2
    • M. J. Phillips, E. T. Perez, J. M. Martin et al., "Modeling human retinal development with patient-specific induced pluripotent stem cells reveals multiple roles for visual system homeobox 2, " Stem Cells, vol. 32, no. 6, pp. 1480-1492, 2014.
    • (2014) Stem Cells , vol.32 , Issue.6 , pp. 1480-1492
    • Phillips, M.J.1    Perez, E.T.2    Martin, J.M.3
  • 35
    • 77955814966 scopus 로고    scopus 로고
    • Reversal of hyperglycemia in diabetic mouse models using induced-pluripotent stem (iPS)-derived pancreatic like cells
    • Z. Alipio, W. Liao, E. J. Roemer et al., "Reversal of hyperglycemia in diabetic mouse models using induced-pluripotent stem (iPS)-derived pancreatic -like cells, " Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 30, pp. 13426-13431, 2010.
    • (2011) Proceedings of the National Academy of Sciences of the United States of America , vol.107 , Issue.30 , pp. 13426-13431
    • Alipio, Z.1    Liao, W.2    Roemer, E.J.3
  • 37
    • 77955454021 scopus 로고    scopus 로고
    • Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury
    • O. Tsuji, K. Miura, Y. Okada et al., "Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury, " Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 28, pp. 12704-12709, 2010.
    • (2011) Proceedings of the National Academy of Sciences of the United States of America , vol.107 , Issue.28 , pp. 12704-12709
    • Tsuji, O.1    Miura, K.2    Okada, Y.3
  • 38
    • 77957670482 scopus 로고    scopus 로고
    • Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats
    • G. Hargus, O. Cooper, M. Deleidi et al., "Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats, " Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 36, pp. 15921-15926, 2010.
    • (2011) Proceedings of the National Academy of Sciences of the United States of America , vol.107 , Issue.36 , pp. 15921-15926
    • Hargus, G.1    Cooper, O.2    Deleidi, M.3
  • 39
    • 37549030199 scopus 로고    scopus 로고
    • Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin
    • J. Hanna, M. Wernig, S. Markoulaki et al., "Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin, " Science, vol. 318, no. 5858, pp. 1920-1923, 2007.
    • (2007) Science , vol.318 , Issue.5858 , pp. 1920-1923
    • Hanna, J.1    Wernig, M.2    Markoulaki, S.3
  • 40
    • 84910673362 scopus 로고    scopus 로고
    • Generation of functional human pancreatic cells in vitro
    • F. W. Pagliuca, J. R. Millman, M. Gurtler et al., "Generation of functional human pancreatic cells in vitro, " Cell, vol. 159, no. 2, pp. 428-439, 2014.
    • (2014) Cell , vol.159 , Issue.2 , pp. 428-439
    • Pagliuca, F.W.1    Millman, J.R.2    Gurtler, M.3
  • 41
    • 57649128308 scopus 로고    scopus 로고
    • Generation of insulin-secreting islet-like clusters from human skinfibroblasts the
    • K. Tateishi, J. He, O. Taranova, G. Liang, A. C. D'Alessio, and Y. Zhang, "Generation of insulin-secreting islet-like clusters from human skinfibroblasts, "The Journal of Biological Chemistry, vol. 283, no. 46, pp. 31601-31607, 2008.
    • (2008) Journal of Biological Chemistry , vol.283 , Issue.46 , pp. 31601-31607
    • Tateishi, K.1    He, J.2    Taranova, O.3    Liang, G.4    D'Alessio, A.C.5    Zhang, Y.6
  • 43
    • 77950965653 scopus 로고    scopus 로고
    • Butyrate greatly enhances derivation of human induced pluripotent stemcells by promoting epigenetic remodeling and the expression of pluripotencyassociated genes
    • P. Mali, B.-K. Chou, J. Yen et al., "Butyrate greatly enhances derivation of human induced pluripotent stemcells by promoting epigenetic remodeling and the expression of pluripotencyassociated genes, " STEMCELLS, vol. 28, no. 4, pp.713-720, 2010.
    • (2011) STEMCELLS , vol.28 , Issue.4 , pp. 713-720
    • Mali, P.1    Chou, B.-K.2    Yen, J.3
  • 44
    • 77955118962 scopus 로고    scopus 로고
    • Generation of human induced pluripotent stem cells by simple transient transfection of plasmid DNA encoding reprogramming factors
    • article 81
    • K. Si-Tayeb, F. K. Noto, A. Sepac et al., "Generation of human induced pluripotent stem cells by simple transient transfection of plasmid DNA encoding reprogramming factors, " BMC Developmental Biology, vol. 10, article 81, 2010.
    • (2011) BMC Developmental Biology , vol.10
    • Si-Tayeb, K.1    Noto, F.K.2    Sepac, A.3
  • 45
    • 70350223975 scopus 로고    scopus 로고
    • Derivation of functional retinal pigmented epithelium frominduced pluripotent stem cells
    • D. E. Buchholz, S. T. Hikita, T. J. Rowland et al., "Derivation of functional retinal pigmented epithelium frominduced pluripotent stem cells, " Stem Cells, vol. 27, no. 10, pp. 2427-2434, 2009.
    • (2009) Stem Cells , vol.27 , Issue.10 , pp. 2427-2434
    • Buchholz, D.E.1    Hikita, S.T.2    Rowl, T.J.3
  • 46
    • 67649880603 scopus 로고    scopus 로고
    • Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases
    • L. Ye, J. C. Chang, C. Lin, X. Sun, J. Yu, and Y. W. Kan, "Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases, " Proceedings of the National Academy of Sciences of the United States of America, vol. 106, no. 24, pp. 9826-9830, 2009.
    • (2009) Proceedings of the National Academy of Sciences of the United States of America , vol.106 , Issue.24 , pp. 9826-9830
    • Ye, L.1    Chang, J.C.2    Lin, C.3    Sun, X.4    Yu, J.5    Kan, Y.W.6
  • 47
    • 78651254192 scopus 로고    scopus 로고
    • Activation of pluripotency genes in human fibroblast cells by a novel mRNA based approach
    • Article IDe14397
    • J.R. Plews, J. Li, M. Jones et al., "Activation of pluripotency genes in human fibroblast cells by a novel mRNA based approach, " PLoS ONE, vol. 5, no. 12, Article IDe14397, 2010.
    • (2011) PLoS ONE , vol.5 , Issue.12
    • Plews, J.R.1    Li, J.2    Jones, M.3
  • 48
    • 65649115029 scopus 로고    scopus 로고
    • Directed differentiation of human-induced pluripotent stem cells generates active motor neurons
    • S. Karumbayaram, B. G. Novitch, M. Patterson et al., "Directed differentiation of human-induced pluripotent stem cells generates active motor neurons, " StemCells, vol. 27, no. 4, pp. 806-811, 2009.
    • (2009) StemCells , vol.27 , Issue.4 , pp. 806-811
    • Karumbayaram, S.1    Novitch, B.G.2    Patterson, M.3
  • 49
    • 38949157774 scopus 로고    scopus 로고
    • Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells
    • F. Osakada, H. Ikeda, M. Mandai et al., "Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells, " Nature Biotechnology, vol. 26, no. 2, pp. 215-224, 2008.
    • (2008) Nature Biotechnology , vol.26 , Issue.2 , pp. 215-224
    • Osakada, F.1    Ikeda, H.2    Mandai, M.3
  • 50
    • 84893748014 scopus 로고    scopus 로고
    • Characterization of human induced pluripotent stem cell-derived retinal pigment epithelium cell sheets aiming for clinical application
    • H. Kamao, M. Mandai, S. Okamoto et al., "Characterization of human induced pluripotent stem cell-derived retinal pigment epithelium cell sheets aiming for clinical application, " Stem Cell Reports, vol. 2, no. 2, pp. 205-218, 2014.
    • (2014) Stem Cell Reports , vol.2 , Issue.2 , pp. 205-218
    • Kamao, H.1    Mandai, M.2    Okamoto, S.3
  • 51
    • 84855387733 scopus 로고    scopus 로고
    • Induction of retinal pigment epithelial cells from monkey iPS cells
    • S. Okamoto and M. Takahashi, "Induction of retinal pigment epithelial cells from monkey iPS cells, " Investigative Ophthalmology and Visual Science, vol. 52, no. 12, pp. 8785-8790, 2011.
    • (2011) Investigative Ophthalmology and Visual Science , vol.52 , Issue.12 , pp. 8785-8790
    • Okamoto, S.1    Takahashi, M.2
  • 52
    • 84897979709 scopus 로고    scopus 로고
    • Tumorigenicity studies of induced pluripotent stem cell (iPSC)-derived retinal pigment epithelium (RPE) for the treatment of age-related macular degeneration
    • Article ID e85336
    • H. Kanemura, M. J. Go, M. Shikamura et al., "Tumorigenicity studies of induced pluripotent stem cell (iPSC)-derived retinal pigment epithelium (RPE) for the treatment of age-related macular degeneration, " PLoS ONE, vol. 9, no. 1, Article ID e85336, 2014.
    • (2014) PLoS ONE , vol.9 , Issue.1
    • Kanemura, H.1    Go, M.J.2    Shikamura, M.3
  • 53
    • 84954513076 scopus 로고    scopus 로고
    • Unexpectedmutations put stemcell trial on hold
    • A. Coghlan, "Unexpectedmutations put stemcell trial on hold, " New Scientist, vol. 227, no. 3033, p. 9, 2015.
    • (2015) New Scientist , vol.227 , Issue.3033 , pp. 9
    • Coghlan, A.1
  • 54
    • 77950669886 scopus 로고    scopus 로고
    • Induced pluripotent stem cells as a model for accelerated patient-And disease-specific drug discovery
    • I. Gunaseeli, M. X. Doss, C. Antzelevitch, J. Hescheler, and A. Sachinidis, "Induced pluripotent stem cells as a model for accelerated patient-And disease-specific drug discovery, " Current Medicinal Chemistry, vol. 17, no. 8, pp. 759-766, 2010.
    • (2011) Current Medicinal Chemistry , vol.17 , Issue.8 , pp. 759-766
    • Gunaseeli, I.1    Doss, M.X.2    Antzelevitch, C.3    Hescheler, J.4    Sachinidis, A.5
  • 55
    • 84880026566 scopus 로고    scopus 로고
    • Genome editing of human pluripotent stemcells to generate human cellular disease models
    • K. Musunuru, "Genome editing of human pluripotent stemcells to generate human cellular disease models, " DiseaseModels and Mechanisms, vol. 6, no. 4, pp. 896-904, 2013.
    • (2013) DiseaseModels and Mechanisms , vol.6 , Issue.4 , pp. 896-904
    • Musunuru, K.1
  • 56
    • 84941172775 scopus 로고    scopus 로고
    • Generation of isogenic human iPS cell line precisely corrected by genome editing using the CRISPR/Cas9 system
    • B. Grobarczyk, B. Franco, K. Hanon, and B. Malgrange, "Generation of isogenic human iPS cell line precisely corrected by genome editing using the CRISPR/Cas9 system, " Stem Cell Reviews and Reports, vol. 11, no. 5, pp. 774-787, 2015.
    • (2015) Stem Cell Reviews and Reports , vol.11 , Issue.5 , pp. 774-787
    • Grobarczyk, B.1    Franco, B.2    Hanon, K.3    Malgrange, B.4
  • 57
    • 34047118522 scopus 로고    scopus 로고
    • CRISPR provides acquired resistance against viruses in prokaryotes
    • R. Barrangou, C. Fremaux, H. Deveau et al., "CRISPR provides acquired resistance against viruses in prokaryotes, " Science, vol. 315, no. 5819, pp. 1709-1712, 2007.
    • (2007) Science , vol.315 , Issue.5819 , pp. 1709-1712
    • Barrangou, R.1    Fremaux, C.2    Deveau, H.3
  • 58
    • 84865070369 scopus 로고    scopus 로고
    • A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
    • M. Jinek, K. Chylinski, I. Fonfara, M. Hauer, J. A. Doudna, and E. Charpentier, "A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity, " Science, vol. 337, no. 6096, pp. 816-821, 2012.
    • (2012) Science , vol.337 , Issue.6096 , pp. 816-821
    • Jinek, M.1    Chylinski, K.2    Fonfara, I.3    Hauer, M.4    Doudna, J.A.5    Charpentier, E.6
  • 59
    • 84873734105 scopus 로고    scopus 로고
    • RNA-guided human genome engineering via Cas9
    • P. Mali, L. Yang, K. M. Esvelt et al., "RNA-guided human genome engineering via Cas9, " Science, vol. 339, no. 6121, pp. 823-826, 2013.
    • (2013) Science , vol.339 , Issue.6121 , pp. 823-826
    • Mali, P.1    Yang, L.2    Esvelt, K.M.3
  • 61
    • 84870583474 scopus 로고    scopus 로고
    • Epigenetic editing: Targeted rewriting of epigenetic marks to modulate expression of selected target genes
    • M. L. De Groote, P. J. Verschure, and M. G. Rots, "Epigenetic editing: targeted rewriting of epigenetic marks to modulate expression of selected target genes, " Nucleic Acids Research, vol. 40, no. 21, pp. 10596-10613, 2012.
    • (2012) Nucleic Acids Research , vol.40 , Issue.21 , pp. 10596-10613
    • De Groote, M.L.1    Verschure, P.J.2    Rots, M.G.3
  • 62
    • 84873729095 scopus 로고    scopus 로고
    • Multiplex genome engineering using CRISPR/Cas systems
    • L. Cong, F. A. Ran, D. Cox et al., "Multiplex genome engineering using CRISPR/Cas systems, " Science, vol. 339, no. 6121, pp. 819-823, 2013.
    • (2013) Science , vol.339 , Issue.6121 , pp. 819-823
    • Cong, L.1    Ran, F.A.2    Cox, D.3
  • 63
    • 10744233606 scopus 로고    scopus 로고
    • Chance or necessity insertional mutagenesis in gene therapy and its consequences
    • C. Baum, C. von Kalle, F. J. T. Staal et al., "Chance or necessity? Insertional mutagenesis in gene therapy and its consequences, " MolecularTherapy, vol. 9, no. 1, pp. 5-13, 2004.
    • (2004) MolecularTherapy , vol.9 , Issue.1 , pp. 5-13
    • Baum, C.1    Von Kalle, C.2    Staal, F.J.T.3
  • 64
    • 84885112722 scopus 로고    scopus 로고
    • Generation of an icf syndrome model by efficient genome editing of human induced pluripotent stem cells using the crispr system
    • T. Horii, D. Tamura, S. Morita, M. Kimura, and I. Hatada, "Generation of an ICF syndrome model by efficient genome editing of human induced pluripotent stem cells using the CRISPR system, " International Journal of Molecular Sciences, vol. 14, no. 10, pp. 19774-19781, 2013.
    • (2013) International Journal of Molecular Sciences , vol.14 , Issue.10 , pp. 19774-19781
    • Horii, T.1    Tamura, D.2    Morita, S.3    Kimura, M.4    Hatada, I.5
  • 65
    • 84938151244 scopus 로고    scopus 로고
    • Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing
    • S. H. Chiou, I. P. Winters, J. Wang et al., "Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing, " Genes &Development, vol. 29, no. 14, pp. 1576-1585, 2015.
    • (2015) Genes &Development , vol.29 , Issue.14 , pp. 1576-1585
    • Chiou, S.H.1    Winters, I.P.2    Wang, J.3
  • 66
    • 84907219050 scopus 로고    scopus 로고
    • Seamless gene correction of -thalassemia mutations in patient-specific iPSCs using CRISPR/Cas9 and piggyBac
    • F. Xie, L. Ye, J. C. Chang et al., "Seamless gene correction of -thalassemia mutations in patient-specific iPSCs using CRISPR/Cas9 and piggyBac, " Genome Research, vol. 24, no. 9, pp. 1526-1533, 2014.
    • (2014) Genome Research , vol.24 , Issue.9 , pp. 1526-1533
    • Xie, F.1    Ye, L.2    Chang, J.C.3
  • 67
    • 84934285785 scopus 로고    scopus 로고
    • Improved hematopoietic differentiation efficiency of gene-corrected beta-thalassemia induced pluripotent stem cells by CRISPR/Cas9 system
    • B. Song, Y. Fan, W. He et al., "Improved hematopoietic differentiation efficiency of gene-corrected beta-thalassemia induced pluripotent stem cells by CRISPR/Cas9 system, " Stem Cells and Development, vol. 24, no. 9, pp. 1053-1065, 2015.
    • (2015) Stem Cells and Development , vol.24 , Issue.9 , pp. 1053-1065
    • Song, B.1    Fan, Y.2    He, W.3
  • 68
    • 84938751866 scopus 로고    scopus 로고
    • Functional correction of large factor VIII gene chromosomal inversions in hemophilia a patient-derived iPSCs using CRISPR-Cas9
    • C. Y. Park, D. H. Kim, J. S. Son et al., "Functional correction of large factor VIII gene chromosomal inversions in hemophilia a patient-derived iPSCs using CRISPR-Cas9, " Cell Stem Cell, vol. 17, no. 2, pp. 213-220, 2015.
    • (2015) Cell Stem Cell , vol.17 , Issue.2 , pp. 213-220
    • Park, C.Y.1    Kim, D.H.2    Son, J.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.