Global genetic analysis in mice unveils central role for cilia in congenital heart disease

Nature

Volumn 521, Issue 7553, 2015, Pages 520-524

  Li, You ^a   Klena, Nikolai T ^a   Gabriel, George C ^a   Liu, Xiaoqin ^a   Kim, Andrew J ^a   Lemke, Kristi ^a   Chen, Yu ^a   Chatterjee, Bishwanath ^a   Devine, William ^a   Damerla, Rama Rao ^a   Chang, Chienfu ^a   Yagi, Hisato ^a   San Agustin, Jovenal T ^b   Thahir, Mohamed ^a,c   Anderton, Shane ^a   Lawhead, Caroline ^a   Vescovi, Anita ^a   Pratt, Herbert ^d   Morgan, Judy ^d   Haynes, Leslie ^d   Smith, Cynthia L ^d   Eppig, Janan T ^d   Reinholdt, Laura ^d   Francis, Richard ^a   Leatherbury, Linda ^e   Ganapathiraju, Madhavi K ^a,c   Tobita, Kimimasa ^a   Pazour, Gregory J ^b   Lo, Cecilia W ^a   more..

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d JACKSON LABORATORY   (United States)

^e CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MULTIPROTEIN COMPLEX; PROTEIN;

CARDIOVASCULAR DISEASE; CELL ORGANELLE; CHROMOSOME; GENETIC ANALYSIS; GENOMICS; MUTATION; NUMERICAL MODEL; PATHOGENICITY; RODENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MIGRATION; CONGENITAL HEART DISEASE; CONTROLLED STUDY; ECHOCARDIOGRAPHY; EUKARYOTIC FLAGELLUM; EXOME; FETUS; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC CODE; GENETIC SCREENING; GENETICS; INTRACELLULAR SIGNALING; MOUSE; MUTAGENESIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RECESSIVE GENE; ANIMAL; C57BL MOUSE; CONGENITAL HEART MALFORMATION; ECHOGRAPHY; ELECTROCARDIOGRAPHY; HUMAN; MALE; MUTATION; NUCLEOTIDE SEQUENCE; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

MUS;

ANIMALS; CILIA; DNA MUTATIONAL ANALYSIS; ELECTROCARDIOGRAPHY; EXOME; GENES, RECESSIVE; GENETIC TESTING; HEART DEFECTS, CONGENITAL; HUMANS; MALE; MICE; MICE, INBRED C57BL; MUTATION; SIGNAL TRANSDUCTION;

EID: 84930660381     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature14269     Document Type: Article

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