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Volumn 39, Issue 17, 2011, Pages 7610-7619

Efficient gene targeting mediated by a lentiviral vector-associated meganuclease

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; LENTIVIRUS VECTOR; MEGANUCLEASE I SCEL; MEGANUCLEASE I SCEL VPR PROTEIN FUSION PROTEIN; NUCLEASE; PUROMYCIN; UNCLASSIFIED DRUG;

EID: 80053195536     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkr524     Document Type: Article
Times cited : (35)

References (47)
  • 1
    • 33645734405 scopus 로고    scopus 로고
    • Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1
    • Ott, M.G., Schmidt, M., Schwarzwaelder, K., Stein, S., Siler, U., Koehl, U., Glimm, H., Kuhlcke, K., Schilz, A., Kunkel, H. et al. (2006) Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1. Nat. Med., 12, 401-409.
    • (2006) Nat. Med. , vol.12 , pp. 401-409
    • Ott, M.G.1    Schmidt, M.2    Schwarzwaelder, K.3    Stein, S.4    Siler, U.5    Koehl, U.6    Glimm, H.7    Kuhlcke, K.8    Schilz, A.9    Kunkel, H.10
  • 5
    • 76249131912 scopus 로고    scopus 로고
    • Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease
    • Stein, S., Ott, M.G., Schultze-Strasser, S., Jauch, A., Burwinkel, B., Kinner, A., Schmidt, M., Kramer, A., Schwable, J., Glimm, H. et al. (2010) Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease. Nat. Med., 16, 198-204.
    • (2010) Nat. Med. , vol.16 , pp. 198-204
    • Stein, S.1    Ott, M.G.2    Schultze-Strasser, S.3    Jauch, A.4    Burwinkel, B.5    Kinner, A.6    Schmidt, M.7    Kramer, A.8    Schwable, J.9    Glimm, H.10
  • 9
    • 56749185598 scopus 로고    scopus 로고
    • A large U3 deletion causes increased in vivo expression from a nonintegrating lentiviral vector
    • Bayer, M., Kantor, B., Cockrell, A., Ma, H., Zeithaml, B., Li, X., McCown, T. and Kafri, T. (2008) A large U3 deletion causes increased in vivo expression from a nonintegrating lentiviral vector. Mol. Ther., 16, 1968-1976.
    • (2008) Mol. Ther. , vol.16 , pp. 1968-1976
    • Bayer, M.1    Kantor, B.2    Cockrell, A.3    Ma, H.4    Zeithaml, B.5    Li, X.6    McCown, T.7    Kafri, T.8
  • 10
    • 32444434997 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 incorporated with fusion proteins consisting of integrase and the designed polydactyl zinc finger protein E2C can bias integration of viral DNA into a predetermined chromosomal region in human cells
    • DOI 10.1128/JVI.80.4.1939-1948.2006
    • Tan, W., Dong, Z., Wilkinson, T.A., Barbas, C.F. III and Chow, S.A. (2006) Human immunodeficiency virus type 1 incorporated with fusion proteins consisting of integrase and the designed polydactyl zinc finger protein E2C can bias integration of viral DNA into a predetermined chromosomal region in human cells. J. Virol., 80, 1939-1948. (Pubitemid 43228733)
    • (2006) Journal of Virology , vol.80 , Issue.4 , pp. 1939-1948
    • Tan, W.1    Dong, Z.2    Wilkinson, T.A.3    Barbas III, C.F.4    Chow, S.A.5
  • 12
    • 33745617039 scopus 로고    scopus 로고
    • Identification and characterization of the chromatin-binding domains of the HIV-1 integrase interactor LEDGF/p75
    • DOI 10.1016/j.jmb.2006.04.073, PII S0022283606005675
    • Llano, M., Vanegas, M., Hutchins, N., Thompson, D., Delgado, S. and Poeschla, E.M. (2006) Identification and characterization of the chromatin-binding domains of the HIV-1 integrase interactor LEDGF/p75. J. Mol. Biol., 360, 760-773. (Pubitemid 43993915)
    • (2006) Journal of Molecular Biology , vol.360 , Issue.4 , pp. 760-773
    • Llano, M.1    Vanegas, M.2    Hutchins, N.3    Thompson, D.4    Delgado, S.5    Poeschla, E.M.6
  • 13
    • 77949707011 scopus 로고    scopus 로고
    • Modification of integration site preferences of an HIV-1-based vector by expression of a novel synthetic protein
    • Silvers, R.M., Smith, J.A., Schowalter, M., Litwin, S., Liang, Z., Geary, K. and Daniel, R. (2010) Modification of integration site preferences of an HIV-1-based vector by expression of a novel synthetic protein. Hum. Gene Ther., 21, 337-349.
    • (2010) Hum. Gene Ther. , vol.21 , pp. 337-349
    • Silvers, R.M.1    Smith, J.A.2    Schowalter, M.3    Litwin, S.4    Liang, Z.5    Geary, K.6    Daniel, R.7
  • 15
    • 0038523969 scopus 로고    scopus 로고
    • Chimeric nucleases stimulate gene targeting in human cells
    • DOI 10.1126/science.1078395
    • Porteus, M.H. and Baltimore, D. (2003) Chimeric nucleases stimulate gene targeting in human cells. Science, 300, 763. (Pubitemid 36532103)
    • (2003) Science , vol.300 , Issue.5620 , pp. 763
    • Porteus, M.H.1    Baltimore, D.2
  • 16
    • 70349404436 scopus 로고    scopus 로고
    • Targeted approaches for gene therapy and the emergence of engineered meganucleases
    • Galetto, R., Duchateau, P. and Paques, F. (2009) Targeted approaches for gene therapy and the emergence of engineered meganucleases. Expert Opin. Biol. Ther., 9, 1289-1303.
    • (2009) Expert Opin. Biol. Ther. , vol.9 , pp. 1289-1303
    • Galetto, R.1    Duchateau, P.2    Paques, F.3
  • 18
    • 36349019180 scopus 로고    scopus 로고
    • Targeted genome modifications using integrase-deficient lentiviral vectors
    • DOI 10.1038/sj.mt.6300345, PII 6300345
    • Cornu, T.I. and Cathomen, T. (2007) Targeted genome modifications using integrase-deficient lentiviral vectors. Mol. Ther., 15, 2107-2113. (Pubitemid 350148926)
    • (2007) Molecular Therapy , vol.15 , Issue.12 , pp. 2107-2113
    • Cornu, T.I.1    Cathomen, T.2
  • 21
    • 0037627488 scopus 로고    scopus 로고
    • Efficient gene targeting mediated by adeno-associated virus and DNA double-strand breaks
    • DOI 10.1128/MCB.23.10.3558-3565.2003
    • Porteus, M.H., Cathomen, T., Weitzman, M.D. and Baltimore, D. (2003) Efficient gene targeting mediated by adeno-associated virus and DNA double-strand breaks. Mol. Cell. Biol., 23, 3558-3565. (Pubitemid 36539188)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.10 , pp. 3558-3565
    • Porteus, M.H.1    Cathomen, T.2    Weitzman, M.D.3    Baltimore, D.4
  • 22
    • 77956617112 scopus 로고    scopus 로고
    • Self-complementary AAV mediates gene targeting and enhances endonuclease delivery for double-strand break repair
    • Hirsch, M.L., Green, L., Porteus, M.H. and Samulski, R.J. (2010) Self-complementary AAV mediates gene targeting and enhances endonuclease delivery for double-strand break repair. Gene Ther., 17, 1175-1180.
    • (2010) Gene Ther , vol.17 , pp. 1175-1180
    • Hirsch, M.L.1    Green, L.2    Porteus, M.H.3    Samulski, R.J.4
  • 23
    • 77951971881 scopus 로고    scopus 로고
    • Fate of recombinant adeno-associated viral vector genomes during DNA double-strand break-induced gene targeting in human cells
    • Gellhaus, K., Cornu, T.I., Heilbronn, R. and Cathomen, T. (2010) Fate of recombinant adeno-associated viral vector genomes during DNA double-strand break-induced gene targeting in human cells. Hum. Gene Ther., 21, 543-553.
    • (2010) Hum. Gene Ther , vol.21 , pp. 543-553
    • Gellhaus, K.1    Cornu, T.I.2    Heilbronn, R.3    Cathomen, T.4
  • 24
    • 77952008829 scopus 로고    scopus 로고
    • Frequent endonuclease cleavage at off-target locations in vivo
    • Petek, L.M., Russell, D.W. and Miller, D.G. (2010) Frequent endonuclease cleavage at off-target locations in vivo. Mol. Ther., 18, 983-986.
    • (2010) Mol. Ther. , vol.18 , pp. 983-986
    • Petek, L.M.1    Russell, D.W.2    Miller, D.G.3
  • 25
    • 61449266636 scopus 로고    scopus 로고
    • Attenuation of zinc finger nuclease toxicity by small-molecule regulation of protein levels
    • Pruett-Miller, S.M., Reading, D.W., Porter, S.N. and Porteus, M.H. (2009) Attenuation of zinc finger nuclease toxicity by small-molecule regulation of protein levels. PLoS Genet., 5, e1000376.
    • (2009) PLoS Genet , vol.5
    • Pruett-Miller, S.M.1    Reading, D.W.2    Porter, S.N.3    Porteus, M.H.4
  • 26
    • 84934436416 scopus 로고    scopus 로고
    • Robust cell line development using meganucleases
    • Cabaniols, J.P. and Paques, F. (2008) Robust cell line development using meganucleases. Methods Mol. Biol., 435, 31-45.
    • (2008) Methods Mol. Biol. , vol.435 , pp. 31-45
    • Cabaniols, J.P.1    Paques, F.2
  • 28
    • 0028919608 scopus 로고
    • Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae
    • Choulika, A., Perrin, A., Dujon, B. and Nicolas, J.F. (1995) Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae. Mol. Cell. Biol., 15, 1968-1973.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1968-1973
    • Choulika, A.1    Perrin, A.2    Dujon, B.3    Nicolas, J.F.4
  • 30
    • 0024549453 scopus 로고
    • Gene targeting with retroviral vectors: Recombination by gene conversion into regions of nonhomology
    • Ellis, J. and Bernstein, A. (1989) Gene targeting with retroviral vectors: recombination by gene conversion into regions of nonhomology. Mol. Cell. Biol., 9, 1621-1627. (Pubitemid 19095202)
    • (1989) Molecular and Cellular Biology , vol.9 , Issue.4 , pp. 1621-1627
    • Ellis, J.1    Bernstein, A.2
  • 31
    • 0032863222 scopus 로고    scopus 로고
    • HIV-1 Vpr-chloramphenicol acetyltransferase fusion proteins: Sequence requirement for virion incorporation and analysis of antiviral effect
    • DOI 10.1038/sj.gt.3300988
    • Yao, X.J., Kobinger, G., Dandache, S., Rougeau, N. and Cohen, E. (1999) HIV-1 Vpr-chloramphenicol acetyltransferase fusion proteins: sequence requirement for virion incorporation and analysis of antiviral effect. Gene Ther., 6, 1590-1599. (Pubitemid 29465518)
    • (1999) Gene Therapy , vol.6 , Issue.9 , pp. 1590-1599
    • Yao, X.-J.1    Kobinger, G.P.2    Dandache, S.3    Rougeau, N.4    Cohen, E.A.5
  • 34
    • 0242600793 scopus 로고    scopus 로고
    • Strand invasion and DNA synthesis from the two 3′ ends of a double-strand break in mammalian cells
    • McCulloch, R.D., Read, L.R. and Baker, M.D. (2003) Strand invasion and DNA synthesis from the two 3' ends of a double-strand break in mammalian cells. Genetics, 163, 1439-1447. (Pubitemid 36523394)
    • (2003) Genetics , vol.163 , Issue.4 , pp. 1439-1447
    • McCulloch, R.D.1    Read, L.R.2    Baker, M.D.3
  • 35
    • 62149146843 scopus 로고    scopus 로고
    • A caveat in mouse genetic engineering: Ectopic gene targeting in ES cells by bidirectional extension of the homology arms of a gene replacement vector carrying human PARP-1
    • Mangerich, A., Scherthan, H., Diefenbach, J., Kloz, U., van der Hoeven, F., Beneke, S. and Burkle, A. (2009) A caveat in mouse genetic engineering: ectopic gene targeting in ES cells by bidirectional extension of the homology arms of a gene replacement vector carrying human PARP-1. Transgenic Res., 18, 261-279.
    • (2009) Transgenic Res , vol.18 , pp. 261-279
    • Mangerich, A.1    Scherthan, H.2    Diefenbach, J.3    Kloz, U.4    Van Der Hoeven, F.5    Beneke, S.6    Burkle, A.7
  • 36
    • 0034653938 scopus 로고    scopus 로고
    • Epitope-tagging approach to determine the stoichiometry of the structural and nonstructural proteins in the virus particles: Amount of Vpr in relation to Gag in HIV-1
    • DOI 10.1006/viro.2000.0191
    • Singh, S.P., Lai, D., Cartas, M., Serio, D., Murali, R., Kalyanaraman, V.S. and Srinivasan, A. (2000) Epitope-tagging approach to determine the stoichiometry of the structural and nonstructural proteins in the virus particles: amount of Vpr in relation to Gag in HIV-1. Virology, 268, 364-371. (Pubitemid 30159985)
    • (2000) Virology , vol.268 , Issue.2 , pp. 364-371
    • Singh, S.P.1    Lai, D.2    Cartas, M.3    Serio, D.4    Murali, R.5    Kalyanaraman, V.S.6    Srinivasan, A.7
  • 37
    • 33846585525 scopus 로고    scopus 로고
    • Generation and characterization of a stable cell population releasing fluorescent HIV-1-based virus like particles in an inducible way
    • Muratori, C., D'Aloja, P., Superti, F., Tinari, A., Sol-Foulon, N., Sparacio, S., Bosch, V., Schwartz, O. and Federico, M. (2006) Generation and characterization of a stable cell population releasing fluorescent HIV-1-based virus like particles in an inducible way. BMC Biotechnol., 6, 52.
    • (2006) BMC Biotechnol , vol.6 , pp. 52
    • Muratori, C.1    D'Aloja, P.2    Superti, F.3    Tinari, A.4    Sol-Foulon, N.5    Sparacio, S.6    Bosch, V.7    Schwartz, O.8    Federico, M.9
  • 38
    • 77951971713 scopus 로고    scopus 로고
    • Production of HIV-1 integrase fusion protein-carrying lentiviral vectors for gene therapy and protein transduction
    • Schenkwein, D., Turkki, V., Karkkainen, H.R., Airenne, K. and Yla-Herttuala, S. (2010) Production of HIV-1 integrase fusion protein-carrying lentiviral vectors for gene therapy and protein transduction. Hum. Gene Ther., 21, 589-602.
    • (2010) Hum. Gene Ther. , vol.21 , pp. 589-602
    • Schenkwein, D.1    Turkki, V.2    Karkkainen, H.R.3    Airenne, K.4    Yla-Herttuala, S.5
  • 41
    • 77957608958 scopus 로고    scopus 로고
    • Site-specific gene insertion mediated by a Cre-loxP-carrying lentiviral vector
    • Michel, G., Yu, Y., Chang, T. and Yee, J.K. (2010) Site-specific gene insertion mediated by a Cre-loxP-carrying lentiviral vector. Mol. Ther., 18, 1814-1821.
    • (2010) Mol. Ther. , vol.18 , pp. 1814-1821
    • Michel, G.1    Yu, Y.2    Chang, T.3    Yee, J.K.4
  • 43
    • 75549087930 scopus 로고    scopus 로고
    • BioNumbers-the database of key numbers in molecular and cell biology
    • Milo, R., Jorgensen, P., Moran, U., Weber, G. and Springer, M. (2010) BioNumbers-the database of key numbers in molecular and cell biology. Nucleic Acids Res., 38, D750-D753.
    • (2010) Nucleic Acids Res , vol.38
    • Milo, R.1    Jorgensen, P.2    Moran, U.3    Weber, G.4    Springer, M.5
  • 44
    • 43049162225 scopus 로고    scopus 로고
    • SnapShot: HIV-1 proteins
    • 742.e1
    • Swanson, C.M. and Malim, M.H. (2008) SnapShot: HIV-1 proteins. Cell, 133, 742, 742.e1.
    • (2008) Cell , vol.133 , pp. 742
    • Swanson, C.M.1    Malim, M.H.2
  • 45
    • 0035876374 scopus 로고    scopus 로고
    • Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection
    • DOI 10.1093/emboj/20.12.3272
    • Li, L., Olvera, J.M., Yoder, K.E., Mitchell, R.S., Butler, S.L., Lieber, M., Martin, S.L. and Bushman, F.D. (2001) Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection. EMBO J., 20, 3272-3281. (Pubitemid 32612014)
    • (2001) EMBO Journal , vol.20 , Issue.12 , pp. 3272-3281
    • Li, L.1    Olvera, J.M.2    Yoder, K.E.3    Mitchell, R.S.4    Butler, S.L.5    Lieber, M.6    Martin, S.L.7    Bushman, F.D.8
  • 46
    • 7044232011 scopus 로고    scopus 로고
    • Homologous recombination generates t-loop-sized deletions at human telomeres
    • DOI 10.1016/j.cell.2004.10.011, PII S0092867404009924
    • Wang, R.C., Smogorzewska, A. and de Lange, T. (2004) Homologous recombination generates T-loop-sized deletions at human telomeres. Cell, 119, 355-368. (Pubitemid 39423838)
    • (2004) Cell , vol.119 , Issue.3 , pp. 355-368
    • Wang, R.C.1    Smogorzewska, A.2    De Lange, T.3


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