Exon capture and bulk segregant analysis: Rapid discovery of causative mutations using high-throughput sequencing

BMC Genomics

Volumn 13, Issue 1, 2012, Pages

  del Viso, Florencia ^a   Bhattacharya, Dipankan ^a   Kong, Yong ^a   Gilchrist, Michael J ^b   Khokha, Mustafa K ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

Bulk segregant analysis; ccdc40; Cilia; Exon capture sequencing; Forward genetics; Genome assembly; Kidney development; pax8; SNP discovery; Xenopus tropicalis

Indexed keywords

ARTICLE; BULK SEGREGANT ANALYSIS; EMBRYO; EXON CAPTURE SEQUENCING; GENE IDENTIFICATION; GENE MAPPING; GENE MUTATION; GENE OVEREXPRESSION; GENETIC PROCEDURES; GENETIC SCREENING; GENOME ANALYSIS; HIGH THROUGHPUT SEQUENCING; LINKAGE ANALYSIS; MOLECULAR CLONING; MUTATIONAL ANALYSIS; NONHUMAN; SEGREGATION ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; XENOPUS TROPICALIS;

ANIMALS; BASE SEQUENCE; CHROMOSOME MAPPING; CLONE CELLS; EXOME; EXONS; GENETIC LINKAGE; GENOTYPE; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; MEIOSIS; MOLECULAR SEQUENCE DATA; MUTATION; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA; XENOPUS; XENOPUS PROTEINS;

MAMMALIA; VERTEBRATA; XENOPUS TROPICALIS;

EID: 84871218754     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-13-649     Document Type: Article

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