Modular degradable dendrimers enable small RNAs to extend survival in an aggressive liver cancer model

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 3, 2016, Pages 520-525

  Zhou, Kejin ^a,b   Nguyen, Liem H ^b,c   Miller, Jason B ^a,b   Yan, Yunfeng ^a,b   Kos, Petra ^a,b   Xiong, Hu ^a,b   Li, Lin ^b,c   Hao, Jing ^a,b   Minnig, Jonathan T ^a,b   Zhu, Hao ^b,c   Siegwart, Daniel J ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Cancer; Dendrimers; MiRNA

Indexed keywords

DENDRIMER; SMALL INTERFERING RNA; DRUG CARRIER; ESTER; MICRORNA; MIRNLET7 MICRORNA, MOUSE; MYC PROTEIN; NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CANCER SURVIVAL; CONTROLLED STUDY; EC50; LIVER CANCER; LIVER TOXICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; THERAPEUTIC INDEX; ANIMAL; BIOLOGICAL MODEL; CELL PROLIFERATION; CHEMISTRY; DRUG DELIVERY SYSTEM; EXTRACELLULAR SPACE; FLUORESCENCE; HELA CELL LINE; HUMAN; INTRACELLULAR SPACE; LIVER TUMOR; METABOLISM; MOLECULAR WEIGHT; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; DENDRIMERS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; ESTERS; EXTRACELLULAR SPACE; FLUORESCENCE; HELA CELLS; HUMANS; INTRACELLULAR SPACE; LIVER NEOPLASMS; MICE; MICRORNAS; MODELS, BIOLOGICAL; MOLECULAR WEIGHT; NANOPARTICLES; PROTO-ONCOGENE PROTEINS C-MYC; RNA, SMALL INTERFERING;

EID: 84955317368     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1520756113     Document Type: Article

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