The Ala86Gln mutant β-lactoglobulin has increased ligand binding and decreased immunoreactivity properties

International Journal of Biological Macromolecules

Volumn 81, Issue , 2015, Pages 340-348

  Kazem Farzandi, Najmeh ^a   Taheri Kafrani, Asghar ^a,b   Haertle, Thomas ^b  

^a UNIVERSITY OF ISFAHAN   (Iran)

^b INRA   (France)

Author keywords

Ala; Alanine; Allergy; CD; circular dichroism; Circular dichroism; CMA; Competitive ELISA; cow's milk allergy; electro spray ionization mass spectrometry; ELISA; enzyme linked immunosorbent assay; ESI MS; Gln; Glutamine; high performance liquid chromatography; HPLC; Ligand binding; Mutation; SDS PAGE; sodium dodecyl sulfate polyacrylamide gel electrophoresis; wild type; WT; Lactoglobulin; lactoglobulin; LG

Indexed keywords

ALANINE; ALANINE 86; BETA LACTOGLOBULIN; EPITOPE; GLUTAMINE; IMMUNOGLOBULIN E; LIGAND; LIPOCALIN; MUTANT PROTEIN; PALMITIC ACID; RECOMBINANT PROTEIN; RESVERATROL; RETINOL; SEROTONIN; UNCLASSIFIED DRUG; CODON; LACTOGLOBULIN; PROTEIN BINDING;

ALLERGENICITY; ARTICLE; BINDING AFFINITY; CIRCULAR DICHROISM; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE SPECTROSCOPY; GENE MUTATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYDROPHOBICITY; IMMUNOREACTIVITY; KOMAGATAELLA PASTORIS; LIGAND BINDING; MASS SPECTROMETRY; MILK; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN FOLDING; PROTEIN STRUCTURE; RECOGNITION; WILD TYPE; ADVERSE EFFECTS; AMINO ACID SUBSTITUTION; ANIMAL; BLOOD; BOVINE; CHEMISTRY; CODON; ELECTROSPRAY MASS SPECTROMETRY; GENETICS; IMMUNOLOGY; ISOLATION AND PURIFICATION; METABOLISM; MILK ALLERGY; MUTATION;

AMINO ACID SUBSTITUTION; ANIMALS; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; CODON; IMMUNOGLOBULIN E; LACTOGLOBULINS; LIGANDS; MILK; MILK HYPERSENSITIVITY; MUTATION; PROTEIN BINDING; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84955287328     PISSN: 01418130     EISSN: 18790003     Source Type: Journal    
DOI: 10.1016/j.ijbiomac.2015.08.013     Document Type: Article

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