Characterization of microbial siderophores by mass spectrometry

Mass Spectrometry Reviews

Volumn 35, Issue 1, 2016, Pages 35-47

  Pluháček, Tomáš ^a,b   Lemr, Karel ^a,b   Ghosh, Dipankar ^c   Milde, David ^a   Novák, Jiří ^b   Havlíček, Vladimír ^a,b  

^a PALACKÝ UNIVERSITY   (Czech Republic)

^b INSTITUTE OF MICROBIOLOGY   (Czech Republic)

^c JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

biomarkers; dereplication; iron; mass spectrometry; siderophores

Indexed keywords

INDUCTIVELY COUPLED PLASMA; INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY; IRON; IRON COMPOUNDS; MASS SPECTROMETERS; MASS SPECTROMETRY; METABOLITES; SPECTROMETRY;

DEREPLICATION; ENRICHMENT APPROACHES; HIGH-RESOLUTION SEPARATIONS; IRON-CONTAINING COMPOUNDS; MICROBIAL SIDEROPHORES; SECONDARY METABOLITES; SIDEROPHORES; TANDEM MASS SPECTROMETRY;

BIOMARKERS;

CHELATING AGENT; SIDEROPHORE;

ANTIBIOTIC RESISTANCE; ATOMIC ABSORPTION SPECTROMETRY; BIOREMEDIATION; CHEMISTRY; MASS SPECTROMETRY; METABOLISM; MICROBIAL SENSITIVITY TEST; PROCEDURES; SECONDARY METABOLISM;

BIODEGRADATION, ENVIRONMENTAL; CHELATING AGENTS; DRUG RESISTANCE, MICROBIAL; MASS SPECTROMETRY; MICROBIAL SENSITIVITY TESTS; SECONDARY METABOLISM; SIDEROPHORES; SPECTROPHOTOMETRY, ATOMIC;

EID: 84955196877     PISSN: 02777037     EISSN: 10982787     Source Type: Journal    
DOI: 10.1002/mas.21461     Document Type: Article

References (105)

1. Ahire JJ, Patil KP, Chaudhari BL, Chincholkar SB,. 2011a. A potential probiotic culture ST2 produces siderophore 2,3-dihydroxybenzoylserine under intestinal conditions. Food Chem 127: 387-393.
2. Ahire JJ, Patil KP, Chaudhari BL, Chincholkar SB,. 2011b. Bacillus spp. of human origin: A potential siderophoregenic probiotic bacteria. Appl Biochem Biotech 164: 386-400.
3. Asmathunisha N, Kathiresan K,. 2013. A review on biosynthesis of nanoparticles by marine organisms. Colloids Surf B Biointerfaces 103: 283-287.
4. Bachman MA, Oyler JE, Burns SH, Caza M, Lepine F, Dozois CM, Weiser JN,. 2011. Klebsiella pneumoniae yersiniabactin promotes respiratory tract infection through evasion of lipocalin 2. Infect Immun 79: 3309-3316.
5. Bassetti M, Merelli M, Temperoni C, Astilean A,. 2013. New antibiotics for bad bugs: Where are we? Ann Clin Microbiol Antimicrob 12: 15.
6. Bertrand S, Larcher G, Landreau A, Richomme P, Duval O, Bouchara JP,. 2009. Hydroxamate siderophores of Scedosporium apiospermum. Biometals 22: 1019-1029.
7. Bhainsa KC, D'Souza SF,. 2006. Extracellular biosynthesis of silver nanoparticles using the fungus Aspergillus fumigatus. Colloids Surf B Biointerfaces 47: 160-164.
8. Bhatt G, Denny TP,. 2004. Ralstonia solanacearum iron scavenging by the siderophore staphyloferrin B is controlled by PhcA, the global virulence regulator. J Bacteriol 186: 7896-7904.
9. Birus M, Gabricevic M, Kronja O, Klaic B,. 1995. C-13 and H-1 NMR line broadening in desferrioxamine-b spectra-kinetics and mechanism of siderophore chemistry. lnorg Chem 34: 3110-3113.
10. Boiteau RM, Fitzsimmons JN, Repeta DJ, Boyle EA,. 2013. Detection of iron ligands in seawater and marine cyanobacteria cultures by high-performance liquid chromatography-inductively coupled plasma-mass spectrometry. Anal Chem 85: 4357-4362.
11. Bottcher T, Clardy J,. 2014. A Chimeric siderophore halts swarming vibrio. Angew Chem Int Edit 53: 3510-3513.
12. Brard L, Granai CO, Swamy N,. 2006. Iron chelators deferoxamine and diethylenetriamine pentaacetic acid induce apoptosis in ovarian carcinoma. Gynecol Oncol 100: 116-127.
13. Budzikiewicz H, Schafer M, Meyer JM,. 2007. Siderotyping of fluorescent pseudomonads-Problems in the determination of molecular masses by mass spectrometry. Mini Rev Org Chem 4: 246-253.
14. Bugdahn N, Peuckert F, Albrecht AG, Miethke M, Marahiel MA, Oberthur M,. 2010. Direct identification of a siderophore import protein using synthetic petrobactin ligands. Angew Chem Int Edit 49: 10210-10213.
15. Bunet R, Riclea R, Laureti L, Hotel L, Paris C, Girardet J-M, Spiteller D, Dickschat JS, Leblond P, Aigle B,. 2014. A single Sfp-Type phosphopantetheinyl transferase plays a major role in the biosynthesis of PKS and NRPS derived metabolites in streptomyces ambofaciens AT CC23877. Plos One 9.
16. Caza M, Lepine F, Milot S, Dozois CM,. 2008. Specific roles of the iroBCDEN genes in virulence of an avian pathogenic Escherichia coli O78 strain and in production of salmochelins. Infect Immun 76: 3539-3549.
17. Costa Mattos AL, Leopoldo Constantino VR, Alves de Couto RA, Luna Pinto DM, Kaneko TM, Esposito BP,. 2013. Desferrioxamine-cadmium as a 'Trojan horse' for the delivery of Cd to bacteria and fungi. J Trace Elem Med Biol 27: 103-108.
18. Dell'mour M, Koellensperger G, Quirino JP, Haddad PR, Stanetty C, Oburger E, Puschenreiter M, Hann S,. 2010. Complexation of metals by phytosiderophores revealed by CE-ESI-MS and CE-ICP-MS. Electrophoresis 31: 1201-1207.
19. Dell'mour M, Schenkeveld W, Oburger E, Fischer L, Kraemer S, Puschenreiter M, Lammerhofer M, Koellensperger G, Hann S,. 2012. Analysis of iron-phytosiderophore complexes in soil related samples: LC-ESI-MS/MS versus CE-MS. Electrophoresis 33: 726-733.
20. Demirev PA, Hagan NS, Antoine MD, Lin JS, Feldman AB,. 2013. Establishing drug resistance in microorganisms by mass spectrometry. J Am Soc Mass Spectrom 24: 1194-1201.
21. Dhungana S, Michalczyk R, Boukhalfa H, Lack JG, Koppisch AT, Fairlee JM, Johnson MT, Ruggiero CE, John SG, Cox MM, Browder CC, Forsythe JH, Vanderberg LA, Neu MP, Hersman LE,. 2007. Purification and characterization of rhodobactin: a mixed ligand siderophore from Rhodococcus rhodochrous strain OFS. Biometals 20: 853-867.
22. Dimkpa CO, Svatos A, Dabrowska P, Schmidt A, Boland W, Kothe E,. 2008. Involvement of siderophores in the reduction of metal-induced inhibition of auxin synthesis in Streptomyces spp. Chemosphere 74: 19-25.
23. Dimkpa CO, Merten D, Svatos A, Buchel G, Kothe E,. 2009a. Metal-induced oxidative stress impacting plant growth in contaminated soil is alleviated by microbial siderophores. Soil Biol Biochem 41: 154-162.
24. Dimkpa CO, Merten D, Svatos A, Buchel G, Kothe E,. 2009b. Siderophores mediate reduced and increased uptake of cadmium by Streptomyces tendae F4 and sunflower (Helianthus annuus), respectively. J Appl Microbiol 107: 1687-1696.
25. Ding P, Helquist P, Miller MJ,. 2008. Design and synthesis of a siderophore conjugate as a potent PSMA inhibitor and potential diagnostic agent for prostate cancer. Biorg Med Chem 16: 1648-1657.
26. Djavaheri M, Mercado-Blanco J, Versluis C, Meyer JM, Loon LC, Bakker PAHM,. 2012. Iron-regulated metabolites produced by Pseudomonas fluorescens WCS374r are not required for eliciting induced systemic resistance against Pseudomonas syringae pv. tomato in Arabidopsis. MicrobiologyOpen 1: 313-325.
27. Duckworth OW, Holmstrom SJM, Pena J, Sposito G,. 2009. Biogeochemistry of iron oxidation in a circumneutral freshwater habitat. Chem Geol 260: 149-158.
28. Ejje N, Soe CZ, Gu J, Codd R,. 2013. The variable hydroxamic acid siderophore metabolome of the marine actinomycete Salinispora tropica CNB-440. Metallomics 5: 1519-1528.
29. Essen SA, Johnsson A, Bylund D, Pedersen K, Lundstrom US,. 2007. Siderophore production by Pseudomonas stutzeri under aerobic and anaerobic conditions. Appl Environ Microb 73: 5857-5864.
30. Expert D, Boughammoura A, Franza T,. 2008. Siderophore-controlled iron assimilation in the enterobacterium erwinia chrysanthemi evidence for the involvement of bacterioferritin and the suf iron-sulfur cluster assembly machinery. J Biol Chem 283: 36564-36572.
31. Fernandes P, de Carvalho CCCR,. 2014. Siderophores as "Trojan Horses": Tackling multidrug resistance? Antimicrob Resist Chemother 5: 290.
32. Flanagan ME, Brickner SJ, Lall M, Casavant J, Deschenes L, Finegan SM, George DM, Granskog K, Hardink JR, Huband MD, Thuy H, Lamb L, Marra A, Mitton-Fry M, Mueller JP, Mullins LM, Noe MC, O'Donnell JP, Pattavina D, Penzien JB, Schuff BP, Sun J, Whipple DA, Young J, Gootz TD,. 2011. Preparation, gram-negative antibacterial activity, and hydrolytic stability of novel siderophore-conjugated monocarbam diols. Acs Med Chem Lett 2: 385-390.
33. Franke J, Ishida K, Hertweck C,. 2014. Evolution of siderophore pathways in human pathogenic bacteria. J Am Chem Soc 136: 5599-5602.
34. Fujita MJ, Nakano K, Sakai R,. 2013. Bisucaberin B, a linear hydroxamate class siderophore from the marine bacterium Tenacibaculum mesophilum. Molecules 18: 3917-3926.
35. Giessen TW, Franke KB, Knappe TA, Kraas FI, Bosello M, Xie X, Linne U, Marahiel MA,. 2012. Isolation, structure elucidation, and biosynthesis of an unusual hydroxamic acid ester-containing siderophore from Actinosynnema mirum. J Nat Prod 75: 905-914.
36. Gledhill M, McCormack P, Ussher S, Achterberg EP, Mantoura RFC, Worsfold PJ,. 2004. Production of siderophore type chelates by mixed bacterioplankton populations in nutrient enriched seawater incubations. Mar Chem 88: 75-83.
37. Haas H,. 2012. Iron-a key nexus in the virulence of Aspergillus fumigatus. Frontiers Microbiol 3: 1-9.
38. Haas H, Eisendle M, Turgeon BG,. 2008. Siderophores in fungal physiology and virulence. Annu Rev Phytopathol 46: 149-187.
39. Haselwandter K, Haninger G, Ganzera M, Haas H, Nicholson G, Winkelmann G,. 2013. Linear fusigen as the major hydroxamate siderophore of the ectomycorrhizal Basidiomycota Laccaria laccata and Laccaria bicolor. Biometals 26: 969-979.
40. Hayen H, Volmer DA,. 2005. Rapid identification of siderophores by combined thin-layer chromatography/matrix-assisted laser desorption/ionization mass spectrometry. Rapid Commun Mass Spectrom 19: 711-720.
41. Hider RC, Kong XL,. 2010. Chemistry and biology of siderophores. Nat Prod Rep 27: 637-657.
42. Hsu C-C, ElNaggar MS, Peng Y, Fang J, Sanchez LM, Mascuch SJ, Moller KA, Alazzeh EK, Pikula J, Quinn RA, Zeng Y, Wolfe BE, Dutton RJ, Gerwick L, Zhang L, Liu X, Mansson M, Dorrestein PC,. 2013. Real-time metabolomics on living microorganisms using ambient electrospray ionization flow-probe. Anal Chem 85: 7014-7018.
43. Hu Q,. 2011. Simultaneous separation and quantification of iron and transition species using LC-ICP-MS. Am J Anal Chem 2: 675-682.
44. Inglis DO, Binkley J, Skrzypek MS, Arnaud MB, Cerqueira GC, Shah P, Wymore F, Wortman JR, Sherlock G,. 2013. Comprehensive annotation of secondary metabolite biosynthetic genes and gene clusters of Aspergillus nidulans, A. fumigatus, A. niger and A. oryzae. Bmc Microbiol 13: 23.
45. Ji C, Miller MJ,. 2012. Chemical syntheses and in vitro antibacterial activity of two desferrioxamine B-ciprofloxacin conjugates with potential esterase and phosphatase triggered drug release linkers. Bioorg Med Chem 20: 3828-3836.
46. Kalb D, Lackner G, Hoffmeister D,. 2013. Fungal peptide synthetases: an update on functions and specificity signatures. Fungal Biol Rev 27: 43-50.
47. Karppi J, Akerman S, Akerman K, Kontturi K, Nyyssonen K, Penttila I,. 2009. Suitability of smopex (R)-102 cation-exchange fiber for analytical purposes and drug monitoring. Pharmazie 64: 14-18.
48. Keeler BD, Brookes MJ,. 2013. Iron chelation: A potential therapeutic strategy in oesophageal cancer. British Journal of Pharmacology 168: 1313-1315.
49. Kellerschierlein W, Hagmann L, Zahner H, Huhn W,. 1988. Metabolic products from microorganisms 250. Maduraferrin, a novel siderophore from actinomadura-madurae. Helv Chim Acta 71: 1528-1540.
50. Klitgaard A, Iversen A, Andersen MR, Larsen TO, Frisvad JC, Nielsen KF,. 2014. Aggressive dereplication using UHPLC-DAD-QTOF: Screening extracts for up to 3000 fungal secondary metabolites. Anal Bioanal Chem 406: 1933-1943.
51. Kodani S, Bicz J, Song L, Deeth RJ, Ohnishi-Kameyama M, Yoshida M, Ochi K, Challis GL,. 2013. Structure and biosynthesis of scabichelin, a novel tris-hydroxamate siderophore produced by the plant pathogen Streptomyces scabies 87.22. Org Biomol Chem 11: 4686-4694.
52. Kolinko I, Lohsse A, Borg S, Raschdorf O, Jogler C, Tu Q, Posfai M, Tompa E, Plitzko JM, Brachmann A, Wanner G, Mueller R, Zhang Y, Schueller D,. 2014. Biosynthesis of magnetic nanostructures in a foreign organism by transfer of bacterial magnetosome gene clusters. Nature Nanotechnol 9: 193-197.
53. Koulman A, Lee TV, Fraser K, Johnson L, Arcus V, Lott JS, Rasmussen S, Lane G,. 2012. Identification of extracellular siderophores and a related peptide from the endophytic fungus Epichloe festucae in culture and endophyte-infected Lolium perenne. Phytochemistry 75: 128-139.
54. Lee TV, Johnson LJ, Johnson RD, Koulman A, Lane GA, Lott JS, Arcus VL,. 2010. Structure of a eukaryotic nonribosomal peptide synthetase adenylation domain that activates a large hydroxamate amino acid in siderophore biosynthesis. J Biol Chem 285: 2415-2427.
55. Lehner SM, Atanasova L, Neumann NKN, Krska R, Lemmens M, Druzhinina IS, Schuhmacher R,. 2013. Isotope-assisted screening for iron-containing metabolites reveals a high degree of diversity among known and unknown siderophores produced by Trichoderma spp. Appl Environ Microbiol 79: 18-31.
56. Ma L, Payne SM., 2012. AhpC is required for optimal production of enterobactin by Escherichia coli. J Bacteriol 194: 6748-6757.
57. Mansson M, Phipps RK, Gram L, Munro MHG, Larsen TO, Nielsen KF,. 2010. Explorative solid-phase extraction (E-SPE) for accelerated microbial natural product discovery, dereplication, and purification. J Nat Prod 73: 1126-1132.
58. Mathavan I, Zirah S, Mehmood S, Choudhury HG, Goulard C, Li Y, Robinson CV, Rebuffat S, Beis K,. 2014. Structural basis for hijacking siderophore receptors by antimicrobial lasso peptides. Nat Chem Biol 10: 340-U123.
59. Mawji E, Gledhill M, Milton JA, Tarran GA, Ussher S, Thompson A, Wolff GA, Worsfold PJ, Achterberg EP., 2008. Hydroxamate siderophores: occurrence and importance in the Atlantic Ocean. Environ Sci Technol 42: 8675-8680.
60. Mawji E, Gledhill M, Milton JA, Zubkov MV, Thompson A, Wolff GA, Achterberg EP,. 2011. Production of siderophore type chelates in Atlantic Ocean waters enriched with different carbon and nitrogen sources. Mar Chem 124: 90-99.
61. McCormack P, Worsfold PJ, Gledhill M,. 2003. Separation and detection of siderophores produced by marine bacterioplankton using high-performance liquid chromatography with electrospray ionization mass spectrometry. Anal Chem 75: 2647-2652.
62. McMillan DGG, Velasquez I, Nunn BL, Goodlett DR, Hunter KA, Lamont I, Sander SG, Cook GM., 2010. Acquisition of iron by alkaliphilic bacillus species. Appl Environ Microb 76: 6955-6961.
63. Meyer J-M, Gruffaz C, Raharinosy V, Bezverbnaya I, Schaefer M, Budzikiewicz H,. 2008. Siderotyping of fluorescent Pseudomonas: molecular mass determination by mass spectrometry as a powerful pyoverdine siderotyping method. Biometals 21: 259-271.
64. Milagres AM, Machuca A, Napoleão D,. 1999. Detection of siderophore production from several fungi and bacteria by a modification of chrome azurol S (CAS) agar plate assay. J Microbiol Methods 37: 1-6.
65. Miller MJ, Zhu H, Xu Y, Wu C, Walz AJ, Vergne A, Roosenberg JM, Moraski G, Minnick AA, McKee-Dolence J, Hu J, Fennell K, Kurt Dolence E, Dong L, Franzblau S, Malouin F, Mollmann U,. 2009. Utilization of microbial iron assimilation processes for the development of new antibiotics and inspiration for the design of new anticancer agents. Biometals 22: 61-75.
66. Milner SJ, Seve A, Snelling AM, Thomas GH, Kerr KG, Routledge A, Duhme-Klair A-K,. 2013. Staphyloferrin A as siderophore-component in fluoroquinolone-based Trojan horse antibiotics. Org Biomol Chem 11: 3461-3468.
67. Moberg M, Nilsson EM, Holmstrom SJM, Lundstrom US, Pettersson J, Markides KE,. 2004. Fingerprinting metal-containing biomolecules after reductive displacement of iron by gallium and subsequent column-switched LC-ICPMS analysis applied on siderophores. Anal Chem 76: 2618-2622.
68. Moree WJ, Phelan VV, Wu CH, Bandeira N, Cornett DS, Duggan BM, Dorrestein PC,. 2012. Interkingdom metabolic transformations captured by microbial imaging mass spectrometry. Proc Natl Acad Sci USA 109: 13811-13816.
69. Moree WJ, Yang JY, Zhao X, Liu W-T, Aparicio M, Atencio L, Ballesteros J, Sanchez J, Gavilan RG, Gutierrez M, Dorrestein PC,. 2013. Imaging mass spectrometry of a coral microbe interaction with fungi. J Chem Ecol 39: 1045-1054.
70. Morgenthau A, Beddek A, Schryvers AB,. 2014. The negatively charged regions of lactoferrin binding protein B, an adaptation against anti-microbial peptides. Plos One 9.
71. Mossialos D, Meyer JM, Budzikiewicz H, Wolff U, Koedam N, Baysse C, Anjaiah VL, Cornelis P,. 2000. Quinolobactin, a new siderophore of Pseudomonas fluorescens ATCC 17400, the production of which is repressed by the cognate pyoverdine. Appl Environ Microb 66: 487-492.
72. Munawar A, Marshall JW, Cox RJ, Bailey AM, Lazarus CM,. 2013. Isolation and characterisation of a ferrirhodin synthetase gene from the sugarcane pathogen Fusarium sacchari. Chembiochem 14: 388-394.
73. Murugappan RM, Aravinth A, Rajaroobia R, Karthikeyan M, Alamelu MR., 2012. Optimization of MM9 medium constituents for enhancement of siderophoregenesis in marine Pseudomonas putida using response surface methodology. Indian J Microbiol 52: 433-441.
74. Naka H, Actis LA, Crosa JH,. 2013. The anguibactin biosynthesis and transport genes are encoded in the chromosome of Vibrio harveyi: a possible evolutionary origin for the pJM1 plasmid-encoded system of Vibrio anguillarum? MicrobiologyOpen 2: 182-194.
75. Naka H, Lopez CS, Crosa JH,. 2008. Reactivation of the vanchrobactin siderophore system of Vibrio anguillarum by removal of a chromosomal insertion sequence originated in plasmid pJM1 encoding the anguibactin siderophore system. Environ Microbiol 10: 265-277.
76. Nielsen KF, Mansson M, Rank C, Frisvad JC, Larsen TO,. 2011. Dereplication of microbial natural products by LC-DAD-TOFMS. J Nat Prod 74: 2338-2348.
77. Pandey RK, Jarvis GG, Low PS,. 2014. Chemical synthesis of staphyloferrin A and its application for Staphylococcus aureus detection. Org Biomol Chem 12: 1707-1710.
78. Parker DL, Lee S-W, Geszvain K, Davis RE, Gruffaz C, Meyer J-M, Torpey JW, Tebo BM,. 2014. Pyoverdine synthesis by the Mn(II)-oxidizing bacterium Pseudomonas putida GB-1. Frontiers Microbiol 5: 1-10.
79. Patel AK, Ahire JJ, Pawar SP, Chaudhari BL, Shouche YS, Chincholkar SB,. 2010. Evaluation of probiotic characteristics of siderophoregenic Bacillus spp. isolated from dairy waste. Appl Biochem Biotech 160: 140-155.
80. Petrik M, Haas H, Dobrozemsky G, Lass-Florl C, Helbok A, Blatzer M, Dietrich H, Decristoforo C,. 2010. Ga-68-siderophores for PET imaging of invasive pulmonary aspergillosis: Proof of principle. J Nucl Med 51: 639-645.
81. Petrik M, Haas H, Laverman P, Schrettl M, Franssen GM, Blatzer M, Decristoforo C,. 2014. Ga-68-triacetylfusarinine C and Ga-68-ferrioxamine E for aspergillus infection imaging: Uptake specificity in various microorganisms. Mol Imaging Biol 16: 102-108.
82. Podkowa KJ, Briere LAK, Heinrichs DE, Shilton BH,. 2014. Crystal and solution structure analysis of FhuD2 from Staphylococcus aureus in multiple unliganded conformations and bound to ferrioxamine-B. Biochemistry 53: 2017-2031.
83. Schalk IJ, Guillon L,. 2013. Pyoverdine biosynthesis and secretion in Pseudomonas aeruginosa: implications for metal homeostasis. Environ Microbiol 15: 1661-1673.
84. Siponen MI, Legrand P, Widdrat M, Jones SR, Zhang W-J, Chang MCY, Faivre D, Arnoux P, Pignol D,. 2013. Structural insight into magnetochrome-mediated magnetite biomineralization. Nature 502: 681-584.
85. Sleno L,. 2012. The use of mass defect in modern mass spectrometry. J Mass Spectrom 47: 226-236.
86. Soe CZ, Codd R,. 2014. Unsaturated macrocyclic dihydroxamic acid siderophores produced by Shewanella putrefaciens using precursor-directed biosynthesis. ACS Chem Biol 9: 945-956.
87. Strohalm M, Kavan D, Novak P, Volny M, Havlicek V,. 2010. mMass 3: A cross-platform software environment for precise analysis of mass spectrometric data. Anal Chem 82: 4648-4651.
88. Sullivan JT, Jeffery EF, Shannon JD, Ramakrishnan G,. 2006. Characterization of the siderophore of Francisella tularensis and role of fsl4 in siderophore production. J Bacteriol 188: 3785-3795.
89. Tomaras AP, Crandon JL, McPherson CJ, Banevicius MA, Finegan SM, Irvine RL, Brown MF, O'Donnell JP, Nicolau DP,. 2013. Adaptation-based resistance to siderophore-conjugated antibacterial agents by Pseudomonas aeruginosa. Antimicrob Agents Chemother 57: 4197-4207.
90. Tortora ML, Diaz-Ricci JC, Pedraza RO,. 2011. Azospirillum brasilense siderophores with antifungal activity against Colletotrichum acutatum. Arch Microbiol 193: 275-286.
91. Tripathi A, Schofield MM, Chlipala GE, Schultz PJ, Yim I, Newmister SA, Nusca TD, Scaglione JB, Hanna PC, Tamayo-Castillo G, Sherman DH,. 2014. Baulamycins A and B, broad-spectrum antibiotics identified as inhibitors of siderophore biosynthesis in Staphylococcus aureus and Bacillus anthracis. J Am Chem Soc 136: 1579-1586.
92. Velasquez I, Nunn BL, Ibisanmi E, Goodlett DR, Hunter KA, Sander SG,. 2011. Detection of hydroxamate siderophores in coastal and Sub-Antarctic waters off the South Eastern Coast of New Zealand. Mar Chem 126: 97-107.
93. Wang WL, Chi Z, Liu GL, Buzdar MA, Chi ZM, Gu QQ,. 2009. Chemical and biological characterization of siderophore produced by the marine-derived Aureobasidium pullulans HN6.2 and its antibacterial activity. Biometals 22: 965-972.
94. Wasylenki LE, Anbar AD, Liermann LJ, Mathur R, Gordon GW, Brantley SL,. 2007. Isotope fractionation during microbial metal uptake measured by MC-ICP-MS. J Anal At Spectrom 22: 905-910.
95. Weber G, von Wiren N, Hayen H,. 2006. Analysis of iron (II)/iron(III) phytosiderophore complexes by nano-electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. Rapid Commun Mass Spectrom 20: 973-980.
96. Weber T, Bongaerts J, Evers S, Maurer K,. 2010. New microorganisms, having at least one mutation in ferric uptake regulator (fur) gene for inhibiting the expression of the fur gene when compared to a second microorganism that does not have the mutation, useful for producing CNY siderophores. Patent No. DE102009000989-A1.
97. Wencewicz TA, Miller MJ,. 2013. Biscatecholate-monohydroxamate mixed ligand siderophore-carbacephalosporin conjugates are selective sideromycin antibiotics that target Acinetobacter baumannii. J Med Chem 56: 4044-4052.
98. Wencewicz TA, Moellmann U, Long TE, Miller MJ,. 2009. Is drug release necessary for antimicrobial activity of siderophore-drug conjugates? Syntheses and biological studies of the naturally occurring salmycin "Trojan Horse" antibiotics and synthetic desferridanoxamine-antibiotic conjugates. Biometals 22: 633-648.
99. Willemse-Erix DFM, Jachtenberg JW, Schut TB, van Leeuwen W, van Belkum A, Puppels G, Maquelin K,. 2010. Towards Raman-based epidemiological typing of Pseudomonas aeruginosa. J Biophotonics 3: 506-511.
100. Wright W, Little J, Liu F, Chakraborty R,. 2013. Isolation and structural identification of the trihydroxamate siderophore vicibactin and its degradative products from Rhizobium leguminosarum ATCC 14479 bv. trifolii. Biometals 26: 271-283.
101. Yang Y-L, Xu Y, Kersten RD, Liu W-T, Meehan MJ, Moore BS, Bandeira N, Dorrestein PC,. 2011. Connecting chemotypes and phenotypes of cultured marine microbial assemblages by imaging mass spectrometry. Angew Chem Int Edit 50: 5839-5842.
102. Ye L, Ballet S, Hildebrand F, Laus G, Guillemyn K, Raes J, Matthijs S, Martins J, Cornelis P,. 2013. A combinatorial approach to the structure elucidation of a pyoverdine siderophore produced by a Pseudomonas putida isolate and the use of pyoverdine as a taxonomic marker for typing P-putida subspecies. Biometals 26: 561-575.
103. Yin WB, Baccile JA, Bok JW, Chen YM, Keller NP, Schroeder FC,. 2013. A nonribosomal peptide synthetase-derived Iron(III) complex from the pathogenic fungus Aspergillus fumigatus. J Am Chem Soc 135: 2064-2067.
104. Zajdowicz S, Haller JC, Krafft AE, Hunsucker SW, Mant CT, Duncan MW, Hodges RS, Jones DNM, Holmes RK,. 2012. Purification and structural characterization of siderophore (Corynebactin) from Corynebacterium diphtheriae. Plos One 7.
105. Zawadzka AM, Nichiporuk R, Abergel RJ, Raymond KN,. 2008. INOR 228-Use of mass spectrometry for characterization of siderophore-binding receptor proteins for iron acquisition in gram-positive bacteria. Abstr Pap Am Chem S 235.