Structure of a eukaryotic nonribosomal peptide synthetase adenylation domain that activates a large hydroxamate amino acid in siderophore biosynthesis

Journal of Biological Chemistry

Volumn 285, Issue 4, 2010, Pages 2415-2427

  Lee, T Verne ^a   Johnson, Linda J ^b   Johnson, Richard D ^b   Koulman, Albert ^b,d   Lane, Geoffrey A ^b   Lott, J Shaun ^a   Arcus, Vickery L ^a,c  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b AGRESEARCH GRASSLANDS   (New Zealand)

^c UNIVERSITY OF WAIKATO   (New Zealand)

^d MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATION; AMINO ACID RESIDUES; BINDING POCKETS; ENDOPHYTIC FUNGI; HYDROXAMATE; MASS SPECTROSCOPY; MULTIDOMAIN PROTEINS; NEW STRUCTURES; NONRIBOSOMAL PEPTIDE SYNTHETASES; PREDICTION METHODS; PROTEIN STRUCTURES; SECONDARY METABOLITES; SIDEROPHORES; SIGNATURE SEQUENCES; SUBSTRATE BINDING;

BIOCHEMISTRY; BIOSYNTHESIS; FUNGI; MASS SPECTROMETRY; METABOLITES; ORGANIC ACIDS; PEPTIDES;

AMINO ACIDS;

AMINO ACID DERIVATIVE; HYDROXAMIC ACID; N DELTA ANHYDROMEVALONYL N DELTA HYDROXY ORNITHINE; PEPTIDE SYNTHASE; SIDEROPHORE; UNCLASSIFIED DRUG; DRUG DERIVATIVE; FUNGAL PROTEIN; NON RIBOSOMAL PEPTIDE SYNTHASE; NON-RIBOSOMAL PEPTIDE SYNTHASE; ORNITHINE;

ADENYLATION; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; CRYSTALLIZATION; EUKARYOTE; MASS SPECTROMETRY; NEOTYPHODIUM; NEOTYPHODIUM LOLII; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROKARYOTE; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; AMINO ACID SEQUENCE; CHEMISTRY; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYMOLOGY; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; POLYADENYLATION; PROTEIN TERTIARY STRUCTURE;

EUKARYOTA; FUNGI; NEOTYPHODIUM LOLII; PROKARYOTA;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; FUNGAL PROTEINS; HYDROXAMIC ACIDS; MOLECULAR SEQUENCE DATA; NEOTYPHODIUM; ORNITHINE; PEPTIDE SYNTHASES; POLYADENYLATION; PROTEIN STRUCTURE, TERTIARY; SIDEROPHORES; SUBSTRATE SPECIFICITY;

EID: 77449129446     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.071324     Document Type: Article

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