Central insulin-like growth factor-1 (IGF-1) restores whole-body insulin action in a model of age-related insulin resistance and IGF-1 decline

Aging Cell

Volumn 15, Issue 1, 2016, Pages 181-186

  Huffman, Derek M ^a   Farias Quipildor, Gabriela ^a   Mao, Kai ^a   Zhang, Xueying ^a,b   Wan, Junxiang ^c   Apontes, Pasha ^a   Cohen, Pinchas ^c   Barzilai, Nir ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b INSTITUTE OF ZOOLOGY   (China)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Aging; Animal models; Central nervous system; Endocrinology; Glucose metabolism; Insulin resistance; Insulin like growth factor

Indexed keywords

GLUCOSE; INSULIN; INSULIN RECEPTOR; PROTEIN KINASE B; SOMATOMEDIN C; GLUCOSE BLOOD LEVEL; INSULIN-LIKE GROWTH FACTOR-1, RAT;

AGED; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENERGY EXPENDITURE; FAT MASS; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GLYCOGEN SYNTHESIS; GLYCOLYSIS; HYPERINSULINEMIC-EUGLYCEMIC CLAMP TECHNIQUE; INSULIN RESISTANCE; INSULIN SENSITIVITY; LONGEVITY; LUNG GAS EXCHANGE; MALE; MEDIOBASAL HYPOTHALAMUS; NONHUMAN; PRIORITY JOURNAL; RAT; ANALYSIS; ANIMAL; DEFICIENCY; GLUCOSE CLAMP TECHNIQUE; LIVER; METABOLISM; PHYSIOLOGY; PROCEDURES; SPRAGUE DAWLEY RAT;

AGING; ANIMALS; BLOOD GLUCOSE; GLUCOSE; GLUCOSE CLAMP TECHNIQUE; INSULIN; INSULIN RESISTANCE; INSULIN-LIKE GROWTH FACTOR I; LIVER; MALE; RATS, SPRAGUE-DAWLEY;

EID: 84955190089     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12415     Document Type: Article

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