Intranasal administration of insulin-like growth factor-1 protects against lipopolysaccharide-induced injury in the developing rat brain

Neuroscience

Volumn 194, Issue , 2011, Pages 195-207

  Cai, Z ^a   Fan, L W ^a   Lin, S ^a   Pang, Y ^a   Rhodes, P G ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptotic cell death; Inflammatory cytokine; Insulin like growth factor 1; Intranasal administration; LPS; Oligodendrocyte

Indexed keywords

INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; RECOMBINANT SOMATOMEDIN C; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN INJURY; BRAIN PROTECTION; BRAIN VENTRICLE DILATATION; CELL ACTIVATION; CINGULATE GYRUS; CONTROLLED STUDY; CORPUS CALLOSUM; DRUG BRAIN LEVEL; DRUG EFFECT; DRUG MECHANISM; FEMALE; INFLAMMATION; LATERAL BRAIN VENTRICLE; MICROGLIA; MYELINATION; NERVE CELL NECROSIS; NEURAL STEM CELL; NEUTROPHIL CHEMOTAXIS; NEWBORN; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; WHITE MATTER;

ADMINISTRATION, INTRANASAL; ANIMALS; ANIMALS, NEWBORN; BRAIN; BRAIN CHEMISTRY; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; INFLAMMATION MEDIATORS; INSULIN-LIKE GROWTH FACTOR I; LIPOPOLYSACCHARIDES; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; WALLERIAN DEGENERATION;

EID: 80053104925     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.08.003     Document Type: Article

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