메뉴 건너뛰기




Volumn 67, Issue , 2016, Pages 201-213

Early combination antiretroviral therapy limits HIV-1 persistence in children

Author keywords

HIV 1 remission; Latent reservoirs; Pediatric HIV 1

Indexed keywords

ANTIRETROVIRUS AGENT; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

EID: 84954507589     PISSN: 00664219     EISSN: 1545326X     Source Type: Book Series    
DOI: 10.1146/annurev-med-091114-111159     Document Type: Article
Times cited : (28)

References (83)
  • 1
    • 84957438806 scopus 로고    scopus 로고
    • UNAIDS. The Gap Report
    • UNAIDS. (2014). Children and pregnant women living with HIV. The Gap Report. http://www.unaids. org/en/resources/documents/2014/childrenandpregnantwomenlivingwithhiv
    • (2014) Children and Pregnant Women Living with HIV
  • 2
    • 0034161410 scopus 로고    scopus 로고
    • Prevention of mother-To-child HIV transmission in resource-poor countries: Translating research into policy and practice
    • De Cock KM, Fowler MG, Mercier E, et al. (2000). Prevention of mother-To-child HIV transmission in resource-poor countries: translating research into policy and practice. JAMA 283: 1175-82
    • (2000) JAMA , vol.283 , pp. 1175-1182
    • De Cock, K.M.1    Fowler, M.G.2    Mercier, E.3
  • 3
    • 84954566662 scopus 로고    scopus 로고
    • Guidelines for the use of antiretroviral agents in pediatric HIV infection
    • AIDSinfo
    • AIDSinfo (2015). Guidelines for the use of antiretroviral agents in pediatric HIV infection.Panel on Antiretroviral Therapy and Medical Management of HIV-Infected Children. http://aidsinfo.nih.gov/contentfiles/lvguidelines/pediatricguidelines.pdf
    • (2015) Panel on Antiretroviral Therapy and Medical Management of HIV-Infected Children
  • 4
    • 0026802456 scopus 로고
    • Proposed definitions for in utero versus intrapartum transmission of HIV-1
    • Bryson YJ, Luzuriaga K, Sullivan JL, et al. (1992). Proposed definitions for in utero versus intrapartum transmission of HIV-1. N. Engl. J. Med. 327: 1246-47
    • (1992) N. Engl. J. Med , vol.327 , pp. 1246-1247
    • Bryson, Y.J.1    Luzuriaga, K.2    Sullivan, J.L.3
  • 5
    • 33750165799 scopus 로고    scopus 로고
    • Mother-To-child transmission of HIV-1: Timing and implications for prevention
    • Kourtis AP, Lee FK, Abrams EJ, et al. (2006). Mother-To-child transmission of HIV-1: timing and implications for prevention. Lancet Infect. Dis. 6: 726-32
    • (2006) Lancet Infect. Dis , vol.6 , pp. 726-732
    • Kourtis, A.P.1    Lee, F.K.2    Abrams, E.J.3
  • 6
    • 0029558404 scopus 로고
    • Estimated timing ofmother-To-child human immunodeficiency virus type 1 (HIV-1) transmission by use of a Markov model
    • The HIV Infection in Newborns French Collaborative Study Group
    • Rouzioux C, Costagliola D, Burgard M, et al. (1995). Estimated timing ofmother-To-child human immunodeficiency virus type 1 (HIV-1) transmission by use of a Markov model. The HIV Infection in Newborns French Collaborative Study Group. Am. J. Epidemiol. 142: 1330-37
    • (1995) Am. J. Epidemiol , vol.142 , pp. 1330-1337
    • Rouzioux, C.1    Costagliola, D.2    Burgard, M.3
  • 7
    • 0027996831 scopus 로고
    • Natural history of vertically acquired human immunodeficiency virus-1 infection
    • The European Collaborative Study
    • The European Collaborative Study. (1994). Natural history of vertically acquired human immunodeficiency virus-1 infection. Pediatrics 94: 815-19
    • (1994) Pediatrics , vol.94 , pp. 815-819
  • 8
    • 15844414680 scopus 로고    scopus 로고
    • Natural history of human immunodeficiency virus disease in perinatally infected children: An analysis from the Pediatric Spectrum of Disease Project
    • Barnhart HX, Caldwell MB, Thomas P, et al. (1996). Natural history of human immunodeficiency virus disease in perinatally infected children: an analysis from the Pediatric Spectrum of Disease Project. Pediatrics 97: 710-16
    • (1996) Pediatrics , vol.97 , pp. 710-716
    • Barnhart, H.X.1    Caldwell, M.B.2    Thomas, P.3
  • 9
    • 84857618321 scopus 로고    scopus 로고
    • Children who acquire HIV infection perinatally are at higher risk of early death than those acquiring infection through breastmilk: A meta-Analysis
    • Becquet R, Marston M, Dabis F, et al. (2012). Children who acquire HIV infection perinatally are at higher risk of early death than those acquiring infection through breastmilk: a meta-Analysis. PLoS ONE 7: e28510
    • (2012) PLoS ONE , vol.7 , pp. e28510
    • Becquet, R.1    Marston, M.2    Dabis, F.3
  • 10
    • 4744348948 scopus 로고    scopus 로고
    • Mortality of infected and uninfected infants born to HIV-infected mothers in Africa: A pooled analysis
    • Newell ML, Coovadia H, Cortina-Borja M, et al. (2004). Mortality of infected and uninfected infants born to HIV-infected mothers in Africa: a pooled analysis. Lancet 364: 1236-43
    • (2004) Lancet , vol.364 , pp. 1236-1243
    • Newell, M.L.1    Coovadia, H.2    Cortina-Borja, M.3
  • 11
    • 0032889324 scopus 로고    scopus 로고
    • Dynamics of human immunodeficiency virus type 1 replication in vertically infected infants
    • Luzuriaga K, Wu H, McManus M, et al. (1999). Dynamics of human immunodeficiency virus type 1 replication in vertically infected infants. J. Virol. 73: 362-67
    • (1999) J. Virol , vol.73 , pp. 362-367
    • Luzuriaga, K.1    Wu, H.2    McManus, M.3
  • 13
    • 34250866984 scopus 로고    scopus 로고
    • Virologic response to potent antiretroviral therapy and modeling of HIV dynamics in early pediatric infection
    • Palumbo P, Wu H, Chadwick E, et al. (2007). Virologic response to potent antiretroviral therapy and modeling of HIV dynamics in early pediatric infection. J. Infect. Dis. 196: 23-29
    • (2007) J. Infect. Dis , vol.196 , pp. 23-29
    • Palumbo, P.1    Wu, H.2    Chadwick, E.3
  • 14
    • 0038617816 scopus 로고    scopus 로고
    • Comparison of human immunodeficiency virus type 1 viral loads in Kenyan women, men, and infants during primary and early infection
    • Richardson BA, Mbori-Ngacha D, Lavreys L, et al. (2003). Comparison of human immunodeficiency virus type 1 viral loads in Kenyan women, men, and infants during primary and early infection. J. Virol. 77: 7120-23
    • (2003) J. Virol , vol.77 , pp. 7120-7123
    • Richardson, B.A.1    Mbori-Ngacha, D.2    Lavreys, L.3
  • 15
    • 2442670578 scopus 로고    scopus 로고
    • Viral load and disease progression in infants infected with human immunodeficiency virus type 1 Women and Infants Transmission Study Group
    • Shearer WT, Quinn TC, LaRussa P, et al. (1997). Viral load and disease progression in infants infected with human immunodeficiency virus type 1.Women and Infants Transmission Study Group. N. Engl. J. Med. 336: 1337-42
    • (1997) N. Engl. J. Med , vol.336 , pp. 1337-1342
    • Shearer, W.T.1    Quinn, T.C.2    LaRussa, P.3
  • 16
    • 0030457164 scopus 로고    scopus 로고
    • Age-And time-related changes in extracellular viral load in children vertically infected by human immunodeficiency virus
    • McIntosh K, Shevitz A, Zaknun D, et al. (1996). Age-And time-related changes in extracellular viral load in children vertically infected by human immunodeficiency virus. Pediatr. Infect. Dis. J. 15: 1087-91
    • (1996) Pediatr. Infect. Dis. J , vol.15 , pp. 1087-1091
    • McIntosh, K.1    Shevitz, A.2    Zaknun, D.3
  • 18
    • 84879880354 scopus 로고    scopus 로고
    • Restrictions to HIV-1 replication in resting CD4+ T lymphocytes
    • Pan X, Baldauf HM, Keppler OT, et al. (2013). Restrictions to HIV-1 replication in resting CD4+ T lymphocytes. Cell Res. 23: 876-85
    • (2013) Cell Res , vol.23 , pp. 876-885
    • Pan, X.1    Baldauf, H.M.2    Keppler, O.T.3
  • 19
    • 84925842804 scopus 로고    scopus 로고
    • Towards an HIV-1 cure: Measuring the latent reservoir
    • Bruner KM, Hosmane NN, Siliciano RF. (2015). Towards an HIV-1 cure: measuring the latent reservoir. Trends Microbiol. 23: 192-203
    • (2015) Trends Microbiol , vol.23 , pp. 192-203
    • Bruner, K.M.1    Hosmane, N.N.2    Siliciano, R.F.3
  • 20
    • 0030913366 scopus 로고    scopus 로고
    • Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection
    • Chun TW, Carruth L, Finzi D, et al. (1997). Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection. Nature 387: 183-88
    • (1997) Nature , vol.387 , pp. 183-188
    • Chun, T.W.1    Carruth, L.2    Finzi, D.3
  • 21
    • 0034076571 scopus 로고    scopus 로고
    • A stable latent reservoir for HIV-1 in resting CD4+ T lymphocytes in infected children
    • Persaud D, Pierson T, Ruff C, et al. (2000). A stable latent reservoir for HIV-1 in resting CD4+ T lymphocytes in infected children. J. Clin. Invest. 105: 995-1003
    • (2000) J. Clin. Invest , vol.105 , pp. 995-1003
    • Persaud, D.1    Pierson, T.2    Ruff, C.3
  • 22
    • 0030990223 scopus 로고    scopus 로고
    • Combination treatment with zidovudine, didanosine, and nevirapine in infants with human immunodeficiency virus type 1 infection
    • Luzuriaga K, Bryson Y, Krogstad P, et al. (1997). Combination treatment with zidovudine, didanosine, and nevirapine in infants with human immunodeficiency virus type 1 infection. N. Engl. J. Med. 336: 1343-49
    • (1997) N. Engl. J. Med , vol.336 , pp. 1343-1349
    • Luzuriaga, K.1    Bryson, Y.2    Krogstad, P.3
  • 23
    • 84864290338 scopus 로고    scopus 로고
    • Dynamics of the resting CD4+ T-cell latent HIV reservoir in infants initiating HAART less than 6 months of age
    • Persaud D, Palumbo PE, Ziemniak C, et al. (2012). Dynamics of the resting CD4+ T-cell latent HIV reservoir in infants initiating HAART less than 6 months of age. AIDS 26: 1483-90
    • (2012) AIDS , vol.26 , pp. 1483-1490
    • Persaud, D.1    Palumbo, P.E.2    Ziemniak, C.3
  • 24
    • 2942625676 scopus 로고    scopus 로고
    • A trial of three antiretroviral regimens in HIV-1-infected children
    • Luzuriaga K, McManus M, Mofenson L, et al. (2004). A trial of three antiretroviral regimens in HIV-1-infected children. N. Engl. J. Med. 350: 2471-80
    • (2004) N. Engl. J. Med , vol.350 , pp. 2471-2480
    • Luzuriaga, K.1    McManus, M.2    Mofenson, L.3
  • 25
    • 42149158210 scopus 로고    scopus 로고
    • Early therapy in HIV-1-infected children: Effect on HIV-1 dynamics and HIV-1-specific immune response
    • Zanchetta M, Anselmi A, Vendrame D, et al. (2008). Early therapy in HIV-1-infected children: effect on HIV-1 dynamics and HIV-1-specific immune response. Antivir. Ther. 13: 47-55
    • (2008) Antivir. Ther , vol.13 , pp. 47-55
    • Zanchetta, M.1    Anselmi, A.2    Vendrame, D.3
  • 26
    • 0028815220 scopus 로고
    • HIV-1-specific cytotoxic T lymphocyte responses in the first year of life
    • Luzuriaga K, Holmes D, Hereema A, et al. (1995). HIV-1-specific cytotoxic T lymphocyte responses in the first year of life. J. Immunol. 154: 433-43
    • (1995) J. Immunol , vol.154 , pp. 433-443
    • Luzuriaga, K.1    Holmes, D.2    Hereema, A.3
  • 27
    • 0031000023 scopus 로고    scopus 로고
    • Early HIV-1 envelope-specific cytotoxic T lymphocyte responses in vertically infected infants
    • Pikora CA, Sullivan JL, Panicali D, et al. (1997). Early HIV-1 envelope-specific cytotoxic T lymphocyte responses in vertically infected infants. J. Exp. Med. 185: 1153-61
    • (1997) J. Exp. Med , vol.185 , pp. 1153-1161
    • Pikora, C.A.1    Sullivan, J.L.2    Panicali, D.3
  • 28
    • 71849093196 scopus 로고    scopus 로고
    • Deficiency of HIV-Gag-specific T cells in early childhood correlates with poor viral containment
    • Huang S, Dunkley-Thompson J, Tang Y, et al. (2008). Deficiency of HIV-Gag-specific T cells in early childhood correlates with poor viral containment. J. Immunol. 181: 8103-11
    • (2008) J. Immunol , vol.181 , pp. 8103-8111
    • Huang, S.1    Dunkley-Thompson, J.2    Tang, Y.3
  • 29
    • 0027465119 scopus 로고
    • Early viremia and immune responses in vertical human immunodeficiency virus type 1 infection
    • Luzuriaga K, McQuilken P, Alimenti A, et al. (1993). Early viremia and immune responses in vertical human immunodeficiency virus type 1 infection. J. Infect. Dis. 167: 1008-13
    • (1993) J. Infect. Dis , vol.167 , pp. 1008-1013
    • Luzuriaga, K.1    McQuilken, P.2    Alimenti, A.3
  • 30
    • 36348978140 scopus 로고    scopus 로고
    • Human immunodeficiency virus-specific CD8+T-cell activity is detectable from birth in the majority of in utero-infected infants
    • Thobakgale CF, Ramduth D, Reddy S, et al. (2007). Human immunodeficiency virus-specific CD8+T-cell activity is detectable from birth in the majority of in utero-infected infants. J. Virol. 81: 12775-84
    • (2007) J. Virol , vol.81 , pp. 12775-12784
    • Thobakgale, C.F.1    Ramduth, D.2    Reddy, S.3
  • 31
    • 84925503671 scopus 로고    scopus 로고
    • Reduced frequencies of polyfunctional CMVspecific T cell responses in infants with congenital CMV infection
    • Gibson L, Barysauskas CM, McManus M, et al. (2015). Reduced frequencies of polyfunctional CMVspecific T cell responses in infants with congenital CMV infection. J. Clin. Immunol. 35: 289-301
    • (2015) J. Clin. Immunol , vol.35 , pp. 289-301
    • Gibson, L.1    Barysauskas, C.M.2    McManus, M.3
  • 32
    • 39549112479 scopus 로고    scopus 로고
    • Detection of HIV type 1 gag-specific CD4+T cell responses in acutely infected infants
    • Ramduth D, Thobakgale CF, Mkhwanazi NP, et al. (2008). Detection of HIV type 1 gag-specific CD4+T cell responses in acutely infected infants. AIDS Res. Hum. Retrovir. 24: 265-70
    • (2008) AIDS Res. Hum. Retrovir , vol.24 , pp. 265-270
    • Ramduth, D.1    Thobakgale, C.F.2    Mkhwanazi, N.P.3
  • 33
    • 0038188721 scopus 로고    scopus 로고
    • HIV-1 replication increases HIV-specific CD4+ T cell frequencies but limits proliferative capacity in chronically infected children
    • Scott ZA, Beaumier CM, Sharkey M, et al. (2003). HIV-1 replication increases HIV-specific CD4+ T cell frequencies but limits proliferative capacity in chronically infected children. J. Immunol. 170: 5786-92
    • (2003) J. Immunol , vol.170 , pp. 5786-5792
    • Scott, Z.A.1    Beaumier, C.M.2    Sharkey, M.3
  • 34
    • 35748961135 scopus 로고    scopus 로고
    • Suppression of SIV-specific CD4 +T cells by infant but not adultmacaque regulatoryTcells: Implications for SIV disease progression
    • Hartigan-O'Connor DJ, Abel K, McCune JM. (2007). Suppression of SIV-specific CD4 +T cells by infant but not adultmacaque regulatoryTcells: implications for SIV disease progression. J. Exp.Med. 204: 2679-92
    • (2007) J. Exp.Med , vol.204 , pp. 2679-2692
    • Hartigan-O'Connor, D.J.1    Abel, K.2    McCune, J.M.3
  • 35
    • 84902131373 scopus 로고    scopus 로고
    • Early development of broadly neutralizing antibodies in HIV-1-infected infants
    • Goo L, Chohan V, Nduati R, et al. (2014). Early development of broadly neutralizing antibodies in HIV-1-infected infants. Nat. Med. 20: 655-58
    • (2014) Nat. Med , vol.20 , pp. 655-658
    • Goo, L.1    Chohan, V.2    Nduati, R.3
  • 36
    • 0030872215 scopus 로고    scopus 로고
    • Delayed generation of antibodies mediating human immunodeficiency virus type 1-specific antibody-dependent cellular cytotoxicity in vertically infected infants
    • Women and Infants Transmission Study Group
    • Pugatch D, Sullivan JL, Pikora CA, et al. (1997). Delayed generation of antibodies mediating human immunodeficiency virus type 1-specific antibody-dependent cellular cytotoxicity in vertically infected infants. Women and Infants Transmission Study Group. J. Infect. Dis. 176: 643-48
    • (1997) J. Infect. Dis , vol.176 , pp. 643-648
    • Pugatch, D.1    Sullivan, J.L.2    Pikora, C.A.3
  • 37
    • 79952451548 scopus 로고    scopus 로고
    • Long-Term outcomes for HIV-infected infants less than 6 months of age at initiation of lopinavir/ritonavir combination antiretroviral therapy
    • Chadwick EG, Yogev R, Alvero CG, et al. (2011). Long-Term outcomes for HIV-infected infants less than 6 months of age at initiation of lopinavir/ritonavir combination antiretroviral therapy. AIDS 25: 643-49
    • (2011) AIDS , vol.25 , pp. 643-649
    • Chadwick, E.G.1    Yogev, R.2    Alvero, C.G.3
  • 38
    • 17544371675 scopus 로고    scopus 로고
    • Early therapy of vertical human immunodeficiency virus type 1 (HIV-1) infection: Control of viral replication and absence of persistent HIV-1-specific immune responses
    • Luzuriaga K, McManus M, Catalina M, et al. (2000). Early therapy of vertical human immunodeficiency virus type 1 (HIV-1) infection: Control of viral replication and absence of persistent HIV-1-specific immune responses. J. Virol. 74: 6984-91
    • (2000) J. Virol , vol.74 , pp. 6984-6991
    • Luzuriaga, K.1    McManus, M.2    Catalina, M.3
  • 39
    • 28744454817 scopus 로고    scopus 로고
    • Seroreversion in children infected with HIV type 1 who are treated in the first months of life is not a rare event
    • Hainaut M, Peltier CA, Goetghebuer T, et al. (2005). Seroreversion in children infected with HIV type 1 who are treated in the first months of life is not a rare event. Clin. Infect. Dis. 41: 1820-21
    • (2005) Clin. Infect. Dis , vol.41 , pp. 1820-1821
    • Hainaut, M.1    Peltier, C.A.2    Goetghebuer, T.3
  • 40
    • 56749097184 scopus 로고    scopus 로고
    • Early antiretroviral therapy and mortality among HIVinfected infants
    • Violari A, Cotton MF, Gibb DM, et al. (2008). Early antiretroviral therapy and mortality among HIVinfected infants. N. Engl. J. Med. 359: 2233-44
    • (2008) N. Engl. J. Med , vol.359 , pp. 2233-2244
    • Violari, A.1    Cotton, M.F.2    Gibb, D.M.3
  • 41
    • 84882279538 scopus 로고    scopus 로고
    • Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection
    • World Health Organization
    • World Health Organization. (2013). Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection. Recommendations for a public health approach. http://www.who.int/hiv/pub/guidelines/arv2013/download/en/
    • (2013) Recommendations for A Public Health Approach
  • 42
    • 84882279538 scopus 로고    scopus 로고
    • March 2014 supplement to the 2013 consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection
    • World Health Organization
    • World Health Organization. (2014). March 2014 supplement to the 2013 consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection. Recommendations for a public health approach. http://www.who.int/hiv/pub/guidelines/arv2013/arvs2013upplement-march2014/en/
    • (2014) Recommendations for A Public Health Approach
  • 43
    • 84954476817 scopus 로고    scopus 로고
    • Guidelines for the use of antiretroviral agents in pediatric HIV infection
    • AIDSinfo
    • AIDSinfo. (2015). Guidelines for the use of antiretroviral agents in pediatric HIV infection. Clinical Guidelines Portal. https://aidsinfo.nih.gov/guidelines/html/2/pediatric-Arv-guidelines/0
    • (2015) Clinical Guidelines Portal
  • 44
    • 84913538191 scopus 로고    scopus 로고
    • HIV-1 DNA decay dynamics in blood during more than a decade of suppressive antiretroviral therapy
    • Besson GJ, Lalama CM, Bosch RJ, et al. (2014). HIV-1 DNA decay dynamics in blood during more than a decade of suppressive antiretroviral therapy. Clin. Infect. Dis. 59: 1312-21
    • (2014) Clin. Infect. Dis , vol.59 , pp. 1312-1321
    • Besson, G.J.1    Lalama, C.M.2    Bosch, R.J.3
  • 45
  • 46
    • 84911005050 scopus 로고    scopus 로고
    • Long-Term antiretroviral treatment initiated at primary HIV-1 infection affects the size, composition, and decay kinetics of the reservoir of HIV-1-infected CD4 T cells
    • Buzon MJ, Martin-Gayo E, Pereyra F, et al. (2014). Long-Term antiretroviral treatment initiated at primary HIV-1 infection affects the size, composition, and decay kinetics of the reservoir of HIV-1-infected CD4 T cells. J. Virol. 88: 10056-65
    • (2014) J. Virol , vol.88 , pp. 10056-10065
    • Buzon, M.J.1    Martin-Gayo, E.2    Pereyra, F.3
  • 47
    • 39349108884 scopus 로고    scopus 로고
    • Dynamics of total, linear nonintegrated, and integrated HIV-1 DNA in vivo and in vitro
    • Koelsch KK, Liu L, Haubrich R, et al. (2008). Dynamics of total, linear nonintegrated, and integrated HIV-1 DNA in vivo and in vitro. J. Infect. Dis. 197: 411-19
    • (2008) J. Infect. Dis , vol.197 , pp. 411-419
    • Koelsch, K.K.1    Liu, L.2    Haubrich, R.3
  • 48
    • 20244376915 scopus 로고    scopus 로고
    • Effect of treatment, during primary infection, on establishment and clearance of cellular reservoirs of HIV-1
    • Strain MC, Little SJ, Daar ES, et al. (2005). Effect of treatment, during primary infection, on establishment and clearance of cellular reservoirs of HIV-1. J. Infect. Dis. 191: 1410-18
    • (2005) J. Infect. Dis , vol.191 , pp. 1410-1418
    • Strain, M.C.1    Little, S.J.2    Daar, E.S.3
  • 49
    • 84954031399 scopus 로고    scopus 로고
    • Cell-Associated HIV-1 DNA and RNA decay dynamics during early combination antiretroviral therapy in HIV-1-infected infants
    • In press
    • Uprety P, Chadwick EG, Rainwater-Lovett K, et al. (2015). Cell-Associated HIV-1 DNA and RNA decay dynamics during early combination antiretroviral therapy in HIV-1-infected infants. Clin. Infect. Dis. In press. doi: 10.1093/cid/civ688
    • (2015) Clin. Infect. Dis
    • Uprety, P.1    Chadwick, E.G.2    Rainwater-Lovett, K.3
  • 50
    • 78549235738 scopus 로고    scopus 로고
    • Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: Implications for eradication
    • Chun TW, Justement JS, Murray D, et al. (2010). Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: implications for eradication. AIDS 24: 2803-8
    • (2010) AIDS , vol.24 , pp. 2803-2808
    • Chun, T.W.1    Justement, J.S.2    Murray, D.3
  • 51
    • 84876411341 scopus 로고    scopus 로고
    • Long-Term antiretroviral therapy initiated during primary HIV-1 infection is key to achieving both low HIV reservoirs and normal T cell counts
    • Hocqueloux L, Avettand-Fenoel V, Jacquot S, et al. (2013). Long-Term antiretroviral therapy initiated during primary HIV-1 infection is key to achieving both low HIV reservoirs and normal T cell counts. J. Antimicrob. Chemother. 68: 1169-78
    • (2013) J. Antimicrob. Chemother , vol.68 , pp. 1169-1178
    • Hocqueloux, L.1    Avettand-Fenoel, V.2    Jacquot, S.3
  • 52
    • 84875985311 scopus 로고    scopus 로고
    • Post-Treatment HIV-1 controllers with a long-Term virological remission after the interruption of early initiated antiretroviral therapy anrs visconti study
    • Saez-Cirion A, Bacchus C, Hocqueloux L, et al. (2013). Post-Treatment HIV-1 controllers with a long-Term virological remission after the interruption of early initiated antiretroviral therapy. ANRS VISCONTI Study. PLoS Pathog. 9: e1003211
    • (2013) PLoS Pathog , vol.9 , pp. e1003211
    • Saez-Cirion, A.1    Bacchus, C.2    Hocqueloux, L.3
  • 53
    • 34247210615 scopus 로고    scopus 로고
    • Slow human immunodeficiency virus type 1 evolution in viral reservoirs in infants treated with effective antiretroviral therapy
    • Persaud D, Ray SC, Kajdas J, et al. (2007). Slow human immunodeficiency virus type 1 evolution in viral reservoirs in infants treated with effective antiretroviral therapy. AIDS Res. Hum. Retrovir. 23: 381-90
    • (2007) AIDS Res. Hum. Retrovir , vol.23 , pp. 381-390
    • Persaud, D.1    Ray, S.C.2    Kajdas, J.3
  • 54
    • 84946096080 scopus 로고    scopus 로고
    • Precise quantitation of the latent HIV-1 reservoir: Implications for eradication strategies
    • Crooks AM, Bateson R, Cope AB, et al. (2015). Precise quantitation of the latent HIV-1 reservoir: implications for eradication strategies. J. Infect. Dis. 212: 1361-65
    • (2015) J. Infect. Dis , vol.212 , pp. 1361-1365
    • Crooks, A.M.1    Bateson, R.2    Cope, A.B.3
  • 55
    • 0038579210 scopus 로고    scopus 로고
    • Long-Term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells
    • Siliciano JD, Kajdas J, Finzi D, et al. (2003). Long-Term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells. Nat. Med. 9: 727-28
    • (2003) Nat. Med , vol.9 , pp. 727-728
    • Siliciano, J.D.1    Kajdas, J.2    Finzi, D.3
  • 56
    • 33744828942 scopus 로고    scopus 로고
    • Long-Term decay of the HIV-1 reservoir in HIV-1-infected children treated with highly active antiretroviral therapy
    • Zanchetta M, Walker S, Burighel N, et al. (2006). Long-Term decay of the HIV-1 reservoir in HIV-1-infected children treated with highly active antiretroviral therapy. J. Infect. Dis. 193: 1718-27
    • (2006) J. Infect. Dis , vol.193 , pp. 1718-1727
    • Zanchetta, M.1    Walker, S.2    Burighel, N.3
  • 57
    • 84911005930 scopus 로고    scopus 로고
    • HIV type 1 (HIV-1) proviral reservoirs decay continuously under sustained virologic control in HIV-1-infected children who received early treatment
    • Luzuriaga K, Tabak B, Garber M, et al. (2014). HIV type 1 (HIV-1) proviral reservoirs decay continuously under sustained virologic control in HIV-1-infected children who received early treatment. J. Infect. Dis. 210: 1529-38
    • (2014) J. Infect. Dis , vol.210 , pp. 1529-1538
    • Luzuriaga, K.1    Tabak, B.2    Garber, M.3
  • 58
    • 68349139711 scopus 로고    scopus 로고
    • HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
    • Chomont N, El-Far M, Ancuta P, et al. (2009). HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation. Nat. Med. 15: 893-900
    • (2009) Nat. Med , vol.15 , pp. 893-900
    • Chomont, N.1    El-Far, M.2    Ancuta, P.3
  • 59
    • 84897553850 scopus 로고    scopus 로고
    • Reduced markers of HIV persistence and restricted HIV-specific immune responses after early antiretroviral therapy in children
    • Ananworanich J, Puthanakit T, Suntarattiwong P, et al. (2014). Reduced markers of HIV persistence and restricted HIV-specific immune responses after early antiretroviral therapy in children. AIDS 28: 1015-20
    • (2014) AIDS , vol.28 , pp. 1015-1020
    • Ananworanich, J.1    Puthanakit, T.2    Suntarattiwong, P.3
  • 60
    • 84936804351 scopus 로고    scopus 로고
    • Early antiretroviral therapy in South African children reduces HIV-1-infected cells and cell-Associated HIV-1 RNA in blood mononuclear cells
    • van Zyl GU, Bedison MA, van Rensburg AJ, et al. (2015). Early antiretroviral therapy in South African children reduces HIV-1-infected cells and cell-Associated HIV-1 RNA in blood mononuclear cells. J. Infect. Dis. 212: 39-43
    • (2015) J. Infect. Dis , vol.212 , pp. 39-43
    • Van Zyl, G.U.1    Bedison, M.A.2    Van Rensburg, A.J.3
  • 61
    • 84930742652 scopus 로고    scopus 로고
    • Influence of age at virologic control on peripheral blood human immunodeficiency virus reservoir size and serostatus in perinatally infected adolescents
    • Persaud D, Patel K, Karalius B, et al. (2014). Influence of age at virologic control on peripheral blood human immunodeficiency virus reservoir size and serostatus in perinatally infected adolescents. JAMA Pediatr. 168: 1138-46
    • (2014) JAMA Pediatr , vol.168 , pp. 1138-1146
    • Persaud, D.1    Patel, K.2    Karalius, B.3
  • 62
    • 84893761231 scopus 로고    scopus 로고
    • HIV-1 persistence in CD4+ T cells with stem cell-like properties
    • Buzon MJ, Sun H, Li C, et al. (2014). HIV-1 persistence in CD4+ T cells with stem cell-like properties. Nat. Med. 20: 139-42
    • (2014) Nat. Med , vol.20 , pp. 139-142
    • Buzon, M.J.1    Sun, H.2    Li, C.3
  • 63
    • 84865717158 scopus 로고    scopus 로고
    • HIV-1 control after transient antiretroviral treatment initiated in primary infection: Role of patient characteristics and effect of therapy
    • Goujard C, Girault I, Rouzioux C, et al. (2012). HIV-1 control after transient antiretroviral treatment initiated in primary infection: role of patient characteristics and effect of therapy. Antivir. Ther. 17: 1001-9
    • (2012) Antivir. Ther , vol.17 , pp. 1001-1009
    • Goujard, C.1    Girault, I.2    Rouzioux, C.3
  • 64
    • 84904545962 scopus 로고    scopus 로고
    • An HIV cure: Feasibility, discovery, and implementation
    • Fauci AS, Marston HD, Folkers GK. (2014). An HIV cure: feasibility, discovery, and implementation. JAMA 312: 335-36
    • (2014) JAMA , vol.312 , pp. 335-336
    • Fauci, A.S.1    Marston, H.D.2    Folkers, G.K.3
  • 65
    • 84918543803 scopus 로고    scopus 로고
    • Very early combination antiretroviral therapy in infants: Prospects for cure
    • Rainwater-Lovett K, Luzuriaga K, Persaud D. (2015). Very early combination antiretroviral therapy in infants: prospects for cure. Curr. Opin. HIV AIDS 10: 4-11
    • (2015) Curr. Opin. HIV AIDS , vol.10 , pp. 4-11
    • Rainwater-Lovett, K.1    Luzuriaga, K.2    Persaud, D.3
  • 66
    • 84907240033 scopus 로고    scopus 로고
    • Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1 PNAS 111: 13475-80; Erratum
    • 2014
    • Hill AL, Rosenbloom DI, Fu F, et al (2014). Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1. PNAS 111: 13475-80; Erratum. (2014). PNAS 111: 5598
    • (2014) PNAS , vol.111 , pp. 5598
    • Hill, A.L.1    Rosenbloom, D.I.2    Fu, F.3
  • 67
    • 84887028999 scopus 로고    scopus 로고
    • Absence of detectableHIV-1 viremia after treatment cessation in an infant
    • Persaud D, Gay H, Ziemniak C, et al. (2013). Absence of detectableHIV-1 viremia after treatment cessation in an infant. N. Engl. J. Med. 369: 1828-35
    • (2013) N. Engl. J. Med , vol.369 , pp. 1828-1835
    • Persaud, D.1    Gay, H.2    Ziemniak, C.3
  • 68
    • 84923064466 scopus 로고    scopus 로고
    • Viremic relapse after HIV-1 remission in a perinatally infected child
    • Luzuriaga K, Gay H, Ziemniak C, et al. (2015). Viremic relapse after HIV-1 remission in a perinatally infected child. N. Engl. J. Med. 372: 786-88
    • (2015) N. Engl. J. Med , vol.372 , pp. 786-788
    • Luzuriaga, K.1    Gay, H.2    Ziemniak, C.3
  • 69
    • 84913586652 scopus 로고    scopus 로고
    • Early initiation of combination antiretroviral therapy in HIV-1-infected newborns can achieve sustained virologic suppression with low frequency of CD4+ T cells carrying HIV in peripheral blood
    • Bitnun A, Samson L, Chun TW, et al. (2014). Early initiation of combination antiretroviral therapy in HIV-1-infected newborns can achieve sustained virologic suppression with low frequency of CD4+ T cells carrying HIV in peripheral blood. Clin. Infect. Dis. 59: 1012-19
    • (2014) Clin. Infect. Dis , vol.59 , pp. 1012-1019
    • Bitnun, A.1    Samson, L.2    Chun, T.W.3
  • 70
    • 84924159785 scopus 로고    scopus 로고
    • Rapid viral rebound after 4 years of suppressive therapy in a seronegative HIV-1 infected infant treated from birth
    • Butler KM, Gavin P, Coughlan S, et al. (2015). Rapid viral rebound after 4 years of suppressive therapy in a seronegative HIV-1 infected infant treated from birth. Pediatr. Infect. Dis. J. 34: e48-51
    • (2015) Pediatr. Infect. Dis. J , vol.34 , pp. e48-51
    • Butler, K.M.1    Gavin, P.2    Coughlan, S.3
  • 71
    • 84915800900 scopus 로고    scopus 로고
    • No cure of HIV infection in a child despite early treatment and apparent viral clearance
    • Giacomet V, Trabattoni D, Zanchetta N, et al. (2014). No cure of HIV infection in a child despite early treatment and apparent viral clearance. Lancet 384: 1320
    • (2014) Lancet , vol.384 , pp. 1320
    • Giacomet, V.1    Trabattoni, D.2    Zanchetta, N.3
  • 74
    • 84886769508 scopus 로고    scopus 로고
    • Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure
    • Ho YC, Shan L, Hosmane NN, et al. (2013). Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure. Cell 155: 540-51
    • (2013) Cell , vol.155 , pp. 540-551
    • Ho, Y.C.1    Shan, L.2    Hosmane, N.N.3
  • 75
    • 84905565097 scopus 로고    scopus 로고
    • Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys
    • Whitney JB, Hill AL, Sanisetty S, et al. (2014). Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys. Nature 512: 74-77
    • (2014) Nature , vol.512 , pp. 74-77
    • Whitney, J.B.1    Hill, A.L.2    Sanisetty, S.3
  • 76
    • 84939865004 scopus 로고    scopus 로고
    • Early antiretroviral therapy in children perinatally infected with HIV: A unique opportunity to implement immunotherapeutic approaches to prolong viral remission
    • Klein N, Palma P, Luzuriaga K, et al. (2015). Early antiretroviral therapy in children perinatally infected with HIV: a unique opportunity to implement immunotherapeutic approaches to prolong viral remission. Lancet Infect. Dis. 15: 1108-14
    • (2015) Lancet Infect. Dis , vol.15 , pp. 1108-1114
    • Klein, N.1    Palma, P.2    Luzuriaga, K.3
  • 77
    • 84904128252 scopus 로고    scopus 로고
    • Immunologic strategies for HIV-1 remission and eradication
    • Barouch DH, Deeks SG. (2014). Immunologic strategies for HIV-1 remission and eradication. Science 345: 169-74
    • (2014) Science , vol.345 , pp. 169-174
    • Barouch, D.H.1    Deeks, S.G.2
  • 78
    • 84922481194 scopus 로고    scopus 로고
    • Eradicating HIV-1 infection: Seeking to clear a persistent pathogen
    • Archin NM, Sung JM, Garrido C, et al. (2014). Eradicating HIV-1 infection: seeking to clear a persistent pathogen. Nat. Rev. Microbiol. 12: 750-64
    • (2014) Nat. Rev. Microbiol , vol.12 , pp. 750-764
    • Archin, N.M.1    Sung, J.M.2    Garrido, C.3
  • 79
    • 84895487305 scopus 로고    scopus 로고
    • Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV
    • Tebas P, Stein D, Tang WW, et al. (2014). Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV. N. Engl. J. Med. 370: 901-10
    • (2014) N. Engl. J. Med , vol.370 , pp. 901-910
    • Tebas, P.1    Stein, D.2    Tang, W.W.3
  • 80
    • 84929855423 scopus 로고    scopus 로고
    • The therapeutic application of CRISPR/Cas9 technologies for HIV
    • Saayman S, Ali SA, Morris KV, et al. (2015). The therapeutic application of CRISPR/Cas9 technologies for HIV. Expert Opin. Biol. Ther. 15: 819-30
    • (2015) Expert Opin. Biol. Ther , vol.15 , pp. 819-830
    • Saayman, S.1    Ali, S.A.2    Morris, K.V.3
  • 81
    • 60549090253 scopus 로고    scopus 로고
    • Long-Term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation
    • Hutter G, Nowak D, Mossner M, et al. (2009). Long-Term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation. N. Engl. J. Med. 360: 692-98
    • (2009) N. Engl. J. Med , vol.360 , pp. 692-698
    • Hutter, G.1    Nowak, D.2    Mossner, M.3
  • 82
    • 84878503062 scopus 로고    scopus 로고
    • Challenges in detecting HIV persistence during potentially curative interventions: A study of the Berlin patient
    • Yukl SA, Boritz E, Busch M, et al. (2013). Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient. PLoS Pathog. 9: e1003347
    • (2013) PLoS Pathog , vol.9 , pp. e1003347
    • Yukl, S.A.1    Boritz, E.2    Busch, M.3
  • 83
    • 84906970468 scopus 로고    scopus 로고
    • Antiretroviral-free HIV-1 remission and viral rebound after allogeneic stem cell transplantation: Report of 2 cases
    • Henrich TJ, Hanhauser E, Marty FM, et al. (2014). Antiretroviral-free HIV-1 remission and viral rebound after allogeneic stem cell transplantation: report of 2 cases. Ann. Intern. Med. 161: 319-27
    • (2014) Ann. Intern. Med , vol.161 , pp. 319-327
    • Henrich, T.J.1    Hanhauser, E.2    Marty, F.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.