Comparative evaluation of in vitro and in vivo high glucose-induced alterations in voltage-gated tetrodotoxin-resistant sodium channel: Effects attenuated by sodium channel blockers

Neuroscience

Volumn 305, Issue , 2015, Pages 183-196

  Kharatmal, S B ^a   Singh, J N ^a   Sharma, S S ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Diabetic neuropathy; Dorsal root ganglion; High glucose; Tetrodotoxin resistant sodium channels; Whole cell patch clamp

Indexed keywords

GLUCOSE; LIDOCAINE; SODIUM CHANNEL NAV1.8; TETRACAINE; TETRODOTOXIN; VOLTAGE GATED SODIUM CHANNEL; ANTINEOPLASTIC ANTIBIOTIC; SODIUM CHANNEL BLOCKING AGENT; STREPTOZOCIN; SWEETENING AGENT;

ADULT; ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOPHYSICS; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CURRENT DENSITY; DRUG MECHANISM; GLUCOSE BLOOD LEVEL; HYPERALGESIA; HYPERGLYCEMIA; HYPERPOLARIZATION; IC50; IN VITRO STUDY; IN VIVO STUDY; MALE; MOTOR NERVE CONDUCTION; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SODIUM CURRENT; SPINAL GANGLION; STEADY STATE; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; STREPTOZOTOCIN-INDUCED DIABETIC NEUROPATHY; SYSTEMIC THERAPY; WHOLE CELL PATCH CLAMP; ANIMAL; CELL CULTURE; CHEMICALLY INDUCED; CYTOLOGY; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODEL; DRUG EFFECTS; DRUG INTERACTION; MEMBRANE POTENTIAL; METABOLISM; PATCH CLAMP TECHNIQUE; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; DRUG INTERACTIONS; GANGLIA, SPINAL; GLUCOSE; LIDOCAINE; MALE; MEMBRANE POTENTIALS; NEURONS; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHANNEL BLOCKERS; STREPTOZOCIN; SWEETENING AGENTS; TETRODOTOXIN; VOLTAGE-GATED SODIUM CHANNELS;

EID: 84954443586     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2015.07.085     Document Type: Article

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