Molecular mechanism for local anesthetic action of eugenol in the rat trigeminal system

Pain

Volumn 144, Issue 1-2, 2009, Pages 84-94

  Park, Chul Kyu ^a   Kim, Kihwan ^a   Jung, Sung Jun ^b   Kim, Min Ji ^c   Ahn, Dong Kuk ^c   Hong, Seong Doo ^d   Kim, Joong Soo ^a   Oh, Seog Bae ^a  

^a Department of Physiology   (South Korea)

^b Kangwon National University   (South Korea)

^c Kyungpook National University   (South Korea)

^d Seoul National University   (South Korea)

Author keywords

Action potentials; Eugenol; Transient receptor potential vanilloid 1; Trigeminal ganglion neurons; Voltage gated sodium channels

Indexed keywords

CAPSAICIN; EUGENOL; ISOLECTIN B4; MESSENGER RNA; SODIUM CHANNEL KV1.8; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL SIZE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; ELECTROMYOGRAM; ELECTROPHYSIOLOGY; ELECTROSTIMULATION; FACE PAIN; HYPERALGESIA; INFERIOR ALVEOLAR NERVE; LOCAL ANESTHESIA; MALE; NOCICEPTION; NONHUMAN; NUCLEOTIDE SEQUENCE; OROFACIAL PAIN; PAIN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TOOTH PULP; TRIGEMINUS GANGLION;

ANALYSIS OF VARIANCE; ANESTHETICS, LOCAL; ANIMALS; ANIMALS, NEWBORN; CAPSAICIN; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROMYOGRAPHY; EUGENOL; GENE EXPRESSION REGULATION; HYPERALGESIA; JAW; LECTINS; MALE; MASTICATORY MUSCLES; MEMBRANE POTENTIALS; NERVE TISSUE PROTEINS; NEURAL INHIBITION; NEURONS; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; REFLEX; SODIUM CHANNELS; TETRODOTOXIN; TOOTH; TRIGEMINAL GANGLION; TRIGEMINAL NERVE; TRPV CATION CHANNELS;

EID: 67349127282     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2009.03.016     Document Type: Article

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