Inhibition of voltage-gated Na + currents in sensory neurones by the sea anemone toxin APETx2

British Journal of Pharmacology

Volumn 165, Issue 7, 2012, Pages 2167-2177

  Blanchard, Maxime G ^a   Rash, Lachlan D ^b   Kellenberger, Stephan ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

acid induced pain; APETx2; ASIC; DRG; inflammatory pain; Na v 1.8; peptide toxin; sea anemone toxins

Indexed keywords

ACID SENSING ION CHANNEL; ACID SENSING ION CHANNEL 3; ANALGESIC AGENT; APETX2 TOXIN; SEA ANEMONE TOXIN; SODIUM CHANNEL NAV1.8; TETRODOTOXIN; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVATION; ENZYME INHIBITION; IC 50; IN VIVO STUDY; MALE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SENSORY NERVE CELL; SPINAL GANGLION; WHOLE CELL; XENOPUS;

ANIMALS; CNIDARIAN VENOMS; FEMALE; GANGLIA, SPINAL; ION CHANNEL GATING; MALE; NERVE TISSUE PROTEINS; OOCYTES; PATCH-CLAMP TECHNIQUES; RATS; RATS, WISTAR; RECOMBINANT PROTEINS; SEA ANEMONES; SENSORY RECEPTOR CELLS; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; XENOPUS LAEVIS;

EID: 84858201111     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01674.x     Document Type: Article

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