Complement C5a-C5aR interaction enhances MAPK signaling pathway activities to mediate renal injury in trichloroethylene sensitized BALB/c mice

Journal of Applied Toxicology

Volumn 36, Issue 2, 2016, Pages 271-284

  Zhang, Jia Xiang ^a   Zha, Wan sheng ^b   Ye, Liang ping ^a   Wang, Feng ^a   Wang, Hui ^a   Shen, Tong ^a   Wu, Chang hao ^c   Zhu, Qi xing ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b Anhui Provincial Committee Hospital   (China)

^c UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

C5a; C5aR; MAPK; Renal injury; Trichloroethylene

Indexed keywords

COMPLEMENT COMPONENT C5A; COMPLEMENT COMPONENT C5A RECEPTOR; COMPLEMENT INHIBITOR; FLUORESCENT DYE; GAMMA INTERFERON; INTERLEUKIN 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TRICHLOROETHYLENE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; W 54011;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; CELL INFILTRATION; COMPLEMENT ACTIVATION; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; FLUORESCENCE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; KIDNEY DYSFUNCTION; KIDNEY FUNCTION; KIDNEY FUNCTION TEST; KIDNEY INJURY; KIDNEY PARENCHYMA; KIDNEY TUBULE DAMAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SKIN SENSITIZATION; TISSUE INJURY; ANIMAL; ANIMAL MODEL; CHEMICALLY INDUCED; DRUG EFFECTS; KIDNEY; KIDNEY DISEASE; METABOLISM; PATHOPHYSIOLOGY;

ANIMALS; COMPLEMENT C5A; KIDNEY; KIDNEY DISEASES; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, ANIMAL; SIGNAL TRANSDUCTION; TRICHLOROETHYLENE;

EID: 84954384006     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.3179     Document Type: Article

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