ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction underlie apoptosis induced by resveratrol and arsenic trioxide in A549 cells

Chemico-Biological Interactions

Volumn 245, Issue , 2016, Pages 100-109

  Gu, Shiyan ^a   Chen, Chengzhi ^a,b   Jiang, Xuejun ^a,b   Zhang, Zunzhen ^a  

^a SICHUAN UNIVERSITY   (China)

^b CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Arsenic trioxide; ER stress; Mitochondrial dysfunction; Resveratrol

Indexed keywords

ACETYLCYSTEINE; ARSENIC TRIOXIDE; CASPASE 12; CASPASE 3; CYTOCHROME C; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; RESVERATROL; TRANSCRIPTION FACTOR NRF2; ANTINEOPLASTIC AGENT; ORGANOARSENIC DERIVATIVE; OXIDE; STILBENE DERIVATIVE;

ADENOCARCINOMA CELL LINE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL SURVIVAL; CELL VIABILITY; COLONY FORMATION; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOSE RESPONSE; DRUG ANTAGONISM; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENTIATION; DRUG SENSITIZATION; ENDOPLASMIC RETICULUM STRESS; G1 PHASE CELL CYCLE CHECKPOINT; G2 PHASE CELL CYCLE CHECKPOINT; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; IC50; LUNG ADENOCARCINOMA; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN EXPRESSION; PROTEIN SECRETION; S PHASE CELL CYCLE CHECKPOINT; ADENOCARCINOMA; DRUG EFFECTS; LUNG; LUNG NEOPLASMS; METABOLISM; MITOCHONDRION; PATHOLOGY; TUMOR CELL LINE;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; APOPTOSIS; ARSENICALS; CELL LINE, TUMOR; DRUG SYNERGISM; ENDOPLASMIC RETICULUM STRESS; HUMANS; LUNG; LUNG NEOPLASMS; MITOCHONDRIA; OXIDES; REACTIVE OXYGEN SPECIES; STILBENES;

EID: 84954348709     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2016.01.005     Document Type: Article

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