TNF-α Inhibits FoxO1 by Upregulating MIR-705 to Aggravate Oxidative Damage in Bone Marrow-Derived Mesenchymal Stem Cells during Osteoporosis

Stem Cells

Volumn 34, Issue 4, 2016, Pages 1054-1067

  Liao, Li ^a   Su, Xiaoxia ^a,b   Yang, Xiaohong ^a,c   Hu, Chenghu ^a   Li, Bei ^a   Lv, Yajie ^d   Shuai, Yi ^a   Jing, Huan ^a   Deng, Zhihong ^e   Jin, Yan ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b XI'AN JIAOTONG UNIVERSITY   (China)

^c ZUNYI MEDICAL UNIVERSITY   (China)

^d FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^e FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Differentiation; Mesenchymal stem cells; miRNA; Osteoporosis; Stem cell microenvironment

Indexed keywords

CATALASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGANESE SUPEROXIDE DISMUTASE; MICRORNA; MICRORNA 705; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR FKHR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTIOXIDANT; ESTROGEN; MIRN705 MICRORNA, MOUSE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BONE MARROW DERIVED MESENCHYMAL STEM CELL; BONE TISSUE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME REPRESSION; ESTROGEN DEFICIENCY; FEMALE; GENE EXPRESSION; GENE FUNCTION; MOUSE; NONHUMAN; OVARIECTOMY; OXIDATIVE STRESS; POSTMENOPAUSE OSTEOPOROSIS; PROTEIN EXPRESSION; REPRESSOR GENE; RNA TRANSCRIPTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; BIOSYNTHESIS; BONE MARROW CELL; DEFICIENCY; GENETICS; HUMAN; MESENCHYMAL STROMA CELL; METABOLISM; OSTEOPOROSIS; PATHOLOGY;

ANIMALS; ANTIOXIDANTS; BONE MARROW CELLS; CATALASE; CELL DIFFERENTIATION; ESTROGENS; FORKHEAD BOX PROTEIN O1; HUMANS; MESENCHYMAL STROMAL CELLS; MICE; MICRORNAS; OSTEOGENESIS; OSTEOPOROSIS; OVARIECTOMY; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84954306743     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2274     Document Type: Article

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