Anti phospholipid antibody-mediated effects in an arterial model of thrombosis are dependent on Toll-like receptor 4

Lupus

Volumn 25, Issue 2, 2016, Pages 162-176

  Laplante, P ^a,e   Fuentes, R ^b,f   Salem, D ^a   Subang, R ^a   Gillis, M A ^c   Hachem, A ^c   Farhat, N ^c,g   Qureshi, S T ^a   Fletcher, C A ^b   Roubey, R A S ^b   Merhi, Y ^c   Thorin, E ^c   Levine, J S ^d   Mackman, N ^b   Rauch, J ^a  

^a RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c MONTREAL HEART INSTITUTE   (Canada)

^d UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^e CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^f CATO RESEARCH LTD   (United States)

^g Pharsight A Certara Company   (Canada)

Author keywords

anti 2 glycoprotein I antibodies; Antiphospholipid syndrome; murine models; thrombosis; tissue factor; Toll like receptor 4

Indexed keywords

BETA2 GLYCOPROTEIN 1 ANTIBODY; FERRIC CHLORIDE; LIGAND; LIPOPOLYSACCHARIDE; PHOSPHOLIPID ANTIBODY; THROMBOPLASTIN; TOLL LIKE RECEPTOR 4; BETA2 GLYCOPROTEIN 1; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPHOSPHOLIPID SYNDROME; ARTERY ENDOTHELIUM; ARTERY THROMBOSIS; ARTICLE; BLOOD CLOTTING; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; INNATE IMMUNITY; LEUKOCYTE; LEUKOCYTE ADHERENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOLOGICAL MODEL; C57BL MOUSE; CELL ADHESION; FEMALE; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; THROMBOSIS; VASCULAR ENDOTHELIUM;

ANIMALS; ANTIBODIES, ANTIPHOSPHOLIPID; ANTIBODIES, MONOCLONAL, MURINE-DERIVED; ANTIPHOSPHOLIPID SYNDROME; BETA 2-GLYCOPROTEIN I; CELL ADHESION; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; IMMUNITY, INNATE; LEUKOCYTES; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; THROMBOPLASTIN; THROMBOSIS; TOLL-LIKE RECEPTOR 4;

EID: 84954289788     PISSN: 09612033     EISSN: 14770962     Source Type: Journal    
DOI: 10.1177/0961203315603146     Document Type: Article

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