Invariant TAD Boundaries Constrain Cell-Type-Specific Looping Interactions between Promoters and Distal Elements around the CFTR Locus

American Journal of Human Genetics

Volumn 98, Issue 1, 2016, Pages 185-201

  Smith, Emily M ^a   Lajoie, Bryan R ^a   Jain, Gaurav ^a   Dekker, Job ^a,b  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

CFTR; chromatin looping; gene regulation; topologically associating domain

Indexed keywords

CAVEOLIN 1; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; TRANSCRIPTION FACTOR CTCF; CFTR PROTEIN, HUMAN; CHROMATIN;

ARTICLE; CELL SPECIFICITY; CHROMOSOME; CHROMOSOME 7; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; EMBRYO; ENHANCER REGION; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION; GENE LOCUS; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN EMBRYONIC STEM CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RESTRICTION FRAGMENT; TOPOLOGICALLY ASSOCIATING DOMAIN; TRANSCRIPTION INITIATION SITE; CELL LINE; CHROMATIN; GENETICS; METABOLISM;

CELL LINE; CHROMATIN; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ENHANCER ELEMENTS, GENETIC; HUMANS; PROMOTER REGIONS, GENETIC;

EID: 84954288250     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2015.12.002     Document Type: Article

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