Oxidative stress regulates CFTR gene expression in human airway epithelial cells through a distal antioxidant response element

American Journal of Respiratory Cell and Molecular Biology

Volumn 52, Issue 3, 2015, Pages 387-396

  Zhang, Zhaolin ^a   Leir, Shih Hsing ^a   Harris, Ann ^a  

^a Lurie Children's Research Center   (United States)

Author keywords

Airway epithelium; Antioxidant response element; CFTR gene expression; Oxidative stress

Indexed keywords

BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; HETERODIMER; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NUCLEAR FACTOR; SULFORAPHANE; TRANSCRIPTION FACTOR NRF2; BACH1 PROTEIN, HUMAN; CFTR PROTEIN, HUMAN; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; FANCONI ANEMIA PROTEIN; MAFK PROTEIN, HUMAN; NFE2L2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MAFK;

AIRWAY EPITHELIAL CELL; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; BINDING SITE; CELL LINE; CONTROLLED STUDY; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR GENE; DISTAL ANTIOXIDANT RESPONSIVE ELEMENT; ENHANCER REGION; ENVIRONMENTAL STRESS; EPITHELIUM CELL; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTESTINE EPITHELIUM CELL; OXIDATIVE STRESS; RESPIRATORY EPITHELIUM; SITE DIRECTED MUTAGENESIS; BRONCHUS; GENETICS; METABOLISM; PROCEDURES; PROMOTER REGION;

AVES;

ANTIOXIDANT RESPONSE ELEMENTS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; BRONCHI; CELL LINE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ENHANCER ELEMENTS, GENETIC; EPITHELIAL CELLS; FANCONI ANEMIA COMPLEMENTATION GROUP PROTEINS; GENE EXPRESSION; HUMANS; MAFK TRANSCRIPTION FACTOR; MUTAGENESIS, SITE-DIRECTED; NF-E2-RELATED FACTOR 2; NF-KAPPA B; OXIDATIVE STRESS; PROMOTER REGIONS, GENETIC; TRANSCRIPTION FACTORS;

EID: 84924120741     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2014-0263OC     Document Type: Article

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