-
1
-
-
15944368960
-
Recent advances in trichosanthin, a ribosome-inactivating protein with multiple pharmacological properties
-
Shaw PC, Lee KM and Wong KB: Recent advances in trichosanthin, a ribosome-inactivating protein with multiple pharmacological properties. Toxicon 45: 683-689, 2005.
-
(2005)
Toxicon
, vol.45
, pp. 683-689
-
-
Shaw, P.C.1
Lee, K.M.2
Wong, K.B.3
-
2
-
-
0022502274
-
Homology of trichosanthin and ricin A chain
-
Zhang XJ and Wang JH: Homology of trichosanthin and ricin A chain. Nature 321: 477-478, 1986.
-
(1986)
Nature
, vol.321
, pp. 477-478
-
-
Zhang, X.J.1
Wang, J.H.2
-
3
-
-
77953161201
-
Possible mechanisms of trichosanthin-induced apoptosis of tumor cells
-
Li M, Li X and Li JC: Possible mechanisms of trichosanthin-induced apoptosis of tumor cells. Anat Rec (Hoboken) 293: 986-992, 2010.
-
(2010)
Anat Rec (Hoboken)
, vol.293
, pp. 986-992
-
-
Li, M.1
Li, X.2
Li, J.C.3
-
4
-
-
0028949396
-
In vitro immunotoxicity and cytotoxicity of trichosanthin against human normal immunocytes and leukemia-lymphoma cells
-
Zheng YT, Zhang WF, Ben KL and Wang JH: In vitro immunotoxicity and cytotoxicity of trichosanthin against human normal immunocytes and leukemia-lymphoma cells. Immunopharmacol Immunotoxicol 17: 69-79, 1995.
-
(1995)
Immunopharmacol Immunotoxicol
, vol.17
, pp. 69-79
-
-
Zheng, Y.T.1
Zhang, W.F.2
Ben, K.L.3
Wang, J.H.4
-
5
-
-
0034644883
-
Capillary electrophoretic determination of apoptosis of HeLa cells induced by trichosanthin
-
Ru QH, Luo GA, Liao JJ and Liu Y: Capillary electrophoretic determination of apoptosis of HeLa cells induced by trichosanthin. J Chromatogr A 894: 165-170, 2000.
-
(2000)
J Chromatogr A
, vol.894
, pp. 165-170
-
-
Ru, Q.H.1
Luo, G.A.2
Liao, J.J.3
Liu, Y.4
-
6
-
-
0035340832
-
Reactive oxygen species involved in trichosanthin-induced apoptosis of human choriocarcinoma cells
-
Zhang C, Gong Y, Ma H, An C, Chen D and Chen ZL: Reactive oxygen species involved in trichosanthin-induced apoptosis of human choriocarcinoma cells. Biochem J 355: 653-661, 2001.
-
(2001)
Biochem J
, vol.355
, pp. 653-661
-
-
Zhang, C.1
Gong, Y.2
Ma, H.3
An, C.4
Chen, D.5
Chen, Z.L.6
-
7
-
-
84866050965
-
Trichosanthin inhibits breast cancer cell proliferation in both cell lines and nude mice by promotion of apoptosis
-
Fang EF, Zhang CZ, Zhang L, Wong JH, Chan YS, Pan WL, Dan XL, Yin CM, Cho CH and Ng TB: Trichosanthin inhibits breast cancer cell proliferation in both cell lines and nude mice by promotion of apoptosis. PLoS One 7: e41592, 2012.
-
(2012)
PLoS One
, vol.7
, pp. e41592
-
-
Fang, E.F.1
Zhang, C.Z.2
Zhang, L.3
Wong, J.H.4
Chan, Y.S.5
Pan, W.L.6
Dan, X.L.7
Yin, C.M.8
Cho, C.H.9
Ng, T.B.10
-
8
-
-
84861581996
-
Trichosanthin down-regulates Notch signaling and inhibits proliferation of the nasopharyngeal carcinoma cell line CNE2 in vitro
-
Liu F, Wang B, Wang Z and Yu S: Trichosanthin down-regulates Notch signaling and inhibits proliferation of the nasopharyngeal carcinoma cell line CNE2 in vitro. Fitoterapia 83: 838-842, 2012.
-
(2012)
Fitoterapia
, vol.83
, pp. 838-842
-
-
Liu, F.1
Wang, B.2
Wang, Z.3
Yu, S.4
-
9
-
-
34447558492
-
Trichosanthin down-regulated p210Bcr-Abl and enhanced imatinib-induced growth arrest in chronic myelogenous leukemia cell line K562
-
Zhang K, Xu J, Huang X, Wu L, Wen C, Hu Y, Su Y, Chen Y and Zhang Z: Trichosanthin down-regulated p210Bcr-Abl and enhanced imatinib-induced growth arrest in chronic myelogenous leukemia cell line K562. Cancer Chemother Pharmacol 60: 581-587, 2007.
-
(2007)
Cancer Chemother Pharmacol
, vol.60
, pp. 581-587
-
-
Zhang, K.1
Xu, J.2
Huang, X.3
Wu, L.4
Wen, C.5
Hu, Y.6
Su, Y.7
Chen, Y.8
Zhang, Z.9
-
10
-
-
78049466464
-
Mechanism of trichosanthin against human leukemia/lymphoma cells in vitro
-
In Chinese
-
Wang YY, Ouyang DY and ZhengxYT: Mechanism of trichosanthin against human leukemia/lymphoma cells in vitro. Zhongguo Shi Yan Xue Ye Xue Za Zhi 15: 729-732, 2007 (In Chinese).
-
(2007)
Zhongguo Shi Yan Xue Ye Xue Za Zhi
, vol.15
, pp. 729-732
-
-
Wang, Y.Y.1
Ouyang, D.Y.2
Zhengx, Y.T.3
-
11
-
-
0035525733
-
Cellular stress response and apoptosis in cancer therapy
-
Herr I and Debatin KM: Cellular stress response and apoptosis in cancer therapy. Blood 98: 2603-2614, 2001.
-
(2001)
Blood
, vol.98
, pp. 2603-2614
-
-
Herr, I.1
Debatin, K.M.2
-
12
-
-
0346873049
-
Anticancer therapy targeting the apoptotic pathway
-
Hu W and Kavanagh JJ: Anticancer therapy targeting the apoptotic pathway. Lancet Oncol 4: 721-729, 2003.
-
(2003)
Lancet Oncol
, vol.4
, pp. 721-729
-
-
Hu, W.1
Kavanagh, J.J.2
-
14
-
-
20444429105
-
Drugs targeting mitochondrial functions to control tumor cell growth
-
Dias N and Bailly C: Drugs targeting mitochondrial functions to control tumor cell growth. Biochem Pharmacol 70: 1-12, 2005.
-
(2005)
Biochem Pharmacol
, vol.70
, pp. 1-12
-
-
Dias, N.1
Bailly, C.2
-
15
-
-
0032526268
-
Apoptosis signaling by death receptors
-
Schulze-Osthoff K, Ferrari D, Los M, Wesselborg S and Peter ME: Apoptosis signaling by death receptors. Eur J Biochem 254: 439-459, 1998.
-
(1998)
Eur J Biochem
, vol.254
, pp. 439-459
-
-
Schulze-Osthoff, K.1
Ferrari, D.2
Los, M.3
Wesselborg, S.4
Peter, M.E.5
-
16
-
-
0032555716
-
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
Luo X, Budihardjo I, Zou H, Slaughter C and Wang X: Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94: 481-490, 1998.
-
(1998)
Cell
, vol.94
, pp. 481-490
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
17
-
-
0033280669
-
Biochemical pathways of caspase activation during apoptosis
-
Budihardjo I, Oliver H, Lutter M, Luo X and Wang X: Biochemical pathways of caspase activation during apoptosis. Annu Rev Cell Dev Biol 15: 269-290, 1999.
-
(1999)
Annu Rev Cell Dev Biol
, vol.15
, pp. 269-290
-
-
Budihardjo, I.1
Oliver, H.2
Lutter, M.3
Luo, X.4
Wang, X.5
-
18
-
-
32544451627
-
Reversal of MDR1/P-glycoprotein-mediated multidrug resistance by vector-based RNA interference in vitro and in vivo
-
Shi Z, Liang YJ, Chen ZS, Wang XW, Wang XH, Ding Y, Chen LM, Yang XP and Fu LW: Reversal of MDR1/P-glycoprotein-mediated multidrug resistance by vector-based RNA interference in vitro and in vivo. Cancer Biol Ther 5:39-47, 2006.
-
(2006)
Cancer Biol Ther
, vol.5
, pp. 39-47
-
-
Shi, Z.1
Liang, Y.J.2
Chen, Z.S.3
Wang, X.W.4
Wang, X.H.5
Ding, Y.6
Chen, L.M.7
Yang, X.P.8
Fu, L.W.9
-
19
-
-
80052941925
-
Recent progress in medicinal investigations on trichosanthin and other ribosome inactivating proteins from the plant genus Trichosanthes
-
Fang EF, Ng TB, Shaw PC and Wong RN: Recent progress in medicinal investigations on trichosanthin and other ribosome inactivating proteins from the plant genus Trichosanthes. Curr Med Chem 18: 4410-4417, 2011.
-
(2011)
Curr Med Chem
, vol.18
, pp. 4410-4417
-
-
Fang, E.F.1
Ng, T.B.2
Shaw, P.C.3
Wong, R.N.4
-
20
-
-
67650751080
-
Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes
-
Galluzzi L, Aaronson SA, Abrams J, Alnemri ES, Andrews DW, Baehrecke EH, Bazan NG, Blagosklonny MV, Blomgren K, Borner C, et al: Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ 16: 1093-1107, 2009.
-
(2009)
Cell Death Differ
, vol.16
, pp. 1093-1107
-
-
Galluzzi, L.1
Aaronson, S.A.2
Abrams, J.3
Alnemri, E.S.4
Andrews, D.W.5
Baehrecke, E.H.6
Bazan, N.G.7
Blagosklonny, M.V.8
Blomgren, K.9
Borner, C.10
-
21
-
-
84904439445
-
Targeting BCL2 for the treatment of lymphoid malignancies
-
Anderson MA, Huang D and Roberts A: Targeting BCL2 for the treatment of lymphoid malignancies. Semin Hematol 51: 219-227, 2014.
-
(2014)
Semin Hematol
, vol.51
, pp. 219-227
-
-
Anderson, M.A.1
Huang, D.2
Roberts, A.3
-
22
-
-
79959886892
-
Navitoclax (ABT-263) accelerates apoptosis during drug-induced mitotic arrest by antagonizing Bcl-xL
-
Shi J, Zhou Y, Huang HC and Mitchison TJ: Navitoclax (ABT-263) accelerates apoptosis during drug-induced mitotic arrest by antagonizing Bcl-xL. Cancer Res 71: 4518-4526, 2011.
-
(2011)
Cancer Res
, vol.71
, pp. 4518-4526
-
-
Shi, J.1
Zhou, Y.2
Huang, H.C.3
Mitchison, T.J.4
-
23
-
-
84877850185
-
ABT-263 enhances sensitivity to metformin and 2-deoxyglucose in pediatric glioma by promoting apoptotic cell death
-
Levesley J, Steele L, Taylor C, Sinha P and Lawler SE: ABT-263 enhances sensitivity to metformin and 2-deoxyglucose in pediatric glioma by promoting apoptotic cell death. PLoS One 8: e64051, 2013.
-
(2013)
PLoS One
, vol.8
, pp. e64051
-
-
Levesley, J.1
Steele, L.2
Taylor, C.3
Sinha, P.4
Lawler, S.E.5
-
24
-
-
33845501864
-
Apoptosome: A platform for the activation of initiator caspases
-
Bao Q and Shi Y: Apoptosome: A platform for the activation of initiator caspases. Cell Death Differ 14: 56-65, 2007.
-
(2007)
Cell Death Differ
, vol.14
, pp. 56-65
-
-
Bao, Q.1
Shi, Y.2
-
25
-
-
0033526812
-
Anti-HIV agent trichosanthin enhances the capabilities of chemokines to stimulate chemotaxis and G protein activation, and this is mediated through interaction of trichosanthin and chemokine receptors
-
Zhao J, Ben LH, Wu YL, Hu W, Ling K, Xin SM, Nie HL, Ma L and Pei G: Anti-HIV agent trichosanthin enhances the capabilities of chemokines to stimulate chemotaxis and G protein activation, and this is mediated through interaction of trichosanthin and chemokine receptors. J Exp Med 190: 101-111, 1999.
-
(1999)
J Exp Med
, vol.190
, pp. 101-111
-
-
Zhao, J.1
Ben, L.H.2
Wu, Y.L.3
Hu, W.4
Ling, K.5
Xin, S.M.6
Nie, H.L.7
Ma, L.8
Pei, G.9
-
26
-
-
67651095933
-
Induced apoptotic action of recombinant trichosanthin in human stomach adenocarcinoma MCG803 cells
-
Xu J, Gao DF, Yan GL and Fan JM: Induced apoptotic action of recombinant trichosanthin in human stomach adenocarcinoma MCG803 cells. Mol Biol Rep 36: 1559-1564, 2009.
-
(2009)
Mol Biol Rep
, vol.36
, pp. 1559-1564
-
-
Xu, J.1
Gao, D.F.2
Yan, G.L.3
Fan, J.M.4
-
27
-
-
77449088580
-
Dexamethasone enhances trichosanthin-induced apoptosis in the HepG2 hepatoma cell line
-
Li M, Chen F, Liu CP, Li DM, Li X, Wang C and Li JC: Dexamethasone enhances trichosanthin-induced apoptosis in the HepG2 hepatoma cell line. Life Sci 86: 10-16, 2010.
-
(2010)
Life Sci
, vol.86
, pp. 10-16
-
-
Li, M.1
Chen, F.2
Liu, C.P.3
Li, D.M.4
Li, X.5
Wang, C.6
Li, J.C.7
-
28
-
-
84894303742
-
Bendamustine combined with rituximab for patients with relapsed or refractory diffuse large B cell lymphoma
-
Vacirca JL, Acs PI, Tabbara IA, et al: Bendamustine combined with rituximab for patients with relapsed or refractory diffuse large B cell lymphoma. Ann Hematol 93: 403-409, 2014.
-
(2014)
Ann Hematol
, vol.93
, pp. 403-409
-
-
Vacirca, J.L.1
Acs, P.I.2
Tabbara, I.A.3
-
30
-
-
34548752232
-
CREB-mediated Bcl-2 expression in trichosanthin-induced Hela cell apoptosis
-
Wang P, Yan H and Li JC: CREB-mediated Bcl-2 expression in trichosanthin-induced Hela cell apoptosis. Biochem Biophys Res Commun 363: 101-105, 2007.
-
(2007)
Biochem Biophys Res Commun
, vol.363
, pp. 101-105
-
-
Wang, P.1
Yan, H.2
Li, J.C.3
-
31
-
-
34347364663
-
Trichosanthin induced apoptosis in HL-60 cells via mitochondrial and endoplasmic reticulum stress signaling pathways
-
Li J, Xia X, Ke Y, Nie H, Smith MA and Zhu X: Trichosanthin induced apoptosis in HL-60 cells via mitochondrial and endoplasmic reticulum stress signaling pathways. Biochim Biophys Acta 1770: 1169-1180, 2007.
-
(2007)
Biochim Biophys Acta
, vol.1770
, pp. 1169-1180
-
-
Li, J.1
Xia, X.2
Ke, Y.3
Nie, H.4
Smith, M.A.5
Zhu, X.6
-
32
-
-
33746889828
-
Trichosanthin suppresses the elevation of p38 MAPK, and Bcl-2 induced by HSV-1 infection in Vero cells
-
Huang H, Chan H, Wang YY, Ouyang DY, Zheng YT and Tam SC: Trichosanthin suppresses the elevation of p38 MAPK, and Bcl-2 induced by HSV-1 infection in Vero cells. Life Sci 79: 1287-1292, 2006.
-
(2006)
Life Sci
, vol.79
, pp. 1287-1292
-
-
Huang, H.1
Chan, H.2
Wang, Y.Y.3
Ouyang, D.Y.4
Zheng, Y.T.5
Tam, S.C.6
-
33
-
-
84881071322
-
Paracrine control of tissue regeneration and cell proliferation by Caspase-3
-
Boland K, Flanagan L and Prehn JH: Paracrine control of tissue regeneration and cell proliferation by Caspase-3. Cell Death Dis 4: e725, 2013.
-
(2013)
Cell Death Dis
, vol.4
, pp. e725
-
-
Boland, K.1
Flanagan, L.2
Prehn, J.H.3
-
34
-
-
0030707519
-
Dismantling cell-cell contacts during apoptosis is coupled to a caspase-dependent proteolytic cleavage of beta-catenin
-
Brancolini C, Lazarevic D, Rodriguez J and Schneider C: Dismantling cell-cell contacts during apoptosis is coupled to a caspase-dependent proteolytic cleavage of beta-catenin. J Cell Biol 139: 759-771, 1997.
-
(1997)
J Cell Biol
, vol.139
, pp. 759-771
-
-
Brancolini, C.1
Lazarevic, D.2
Rodriguez, J.3
Schneider, C.4
-
35
-
-
0037470777
-
Caspase-dependent cleavage of tensin induces disruption of actin cytoskeleton during apoptosis
-
Kook S, Kim DH, Shim SR, Kim W, Chun JS and Song WK: Caspase-dependent cleavage of tensin induces disruption of actin cytoskeleton during apoptosis. Biochem Biophys Res Commun 303: 37-45, 2003.
-
(2003)
Biochem Biophys Res Commun
, vol.303
, pp. 37-45
-
-
Kook, S.1
Kim, D.H.2
Shim, S.R.3
Kim, W.4
Chun, J.S.5
Song, W.K.6
-
37
-
-
0030820875
-
Caspase-3-generated fragment of gelsolin: Effector of morphological change in apoptosis
-
Kothakota S, Azuma T, Reinhard C, Klippel A, Tang J, Chu K, McGarry TJ, Kirschner MW, Koths K, Kwiatkowski DJ and Williams LT: Caspase-3-generated fragment of gelsolin: Effector of morphological change in apoptosis. Science 278: 294-298, 1997.
-
(1997)
Science
, vol.278
, pp. 294-298
-
-
Kothakota, S.1
Azuma, T.2
Reinhard, C.3
Klippel, A.4
Tang, J.5
Chu, K.6
McGarry, T.J.7
Kirschner, M.W.8
Koths, K.9
Kwiatkowski, D.J.10
Williams, L.T.11
-
38
-
-
0033709907
-
Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation
-
Zheng TS, Hunot S, Kuida K, Momoi T, Srinivasan A, Nicholson DW, Lazebnik Y and Flavell RA: Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation. Nat Med 6: 1241-1247, 2000.
-
(2000)
Nat Med
, vol.6
, pp. 1241-1247
-
-
Zheng, T.S.1
Hunot, S.2
Kuida, K.3
Momoi, T.4
Srinivasan, A.5
Nicholson, D.W.6
Lazebnik, Y.7
Flavell, R.A.8
-
39
-
-
32444434664
-
Caspases 3 and 7: Key mediators of mitochondrial events of apoptosis
-
Lakhani SA, Masud A, Kuida K, Porter GA Jr, Booth CJ, Mehal WZ, Inayat I and Flavell RA: Caspases 3 and 7: Key mediators of mitochondrial events of apoptosis. Science 311: 847-851, 2006.
-
(2006)
Science
, vol.311
, pp. 847-851
-
-
Lakhani, S.A.1
Masud, A.2
Kuida, K.3
Porter, G.A.4
Booth, C.J.5
Mehal, W.Z.6
Inayat, I.7
Flavell, R.A.8
-
40
-
-
84911432841
-
Achyranthes aspera root extracts induce human colon cancer cell (COLO-205) death by triggering the mitochondrial apoptosis pathway and S phase cell cycle arrest
-
Arora S and Tandon S: Achyranthes aspera root extracts induce human colon cancer cell (COLO-205) death by triggering the mitochondrial apoptosis pathway and S phase cell cycle arrest. ScientificWorldJournal 2014: 129697, 2014.
-
(2014)
ScientificWorldJournal
, vol.2014
, pp. 129697
-
-
Arora, S.1
Tandon, S.2
-
41
-
-
78049452855
-
The mechanisms of action of Tianhua(™) on antitumor activity in lung cancer cells
-
Li CT, Lin CH, Kao TY, Wu MF, Yeh CS, Yeh KT and Ko JL: The mechanisms of action of Tianhua(™) on antitumor activity in lung cancer cells. Pharm Biol 48: 1302-1309, 2010.
-
(2010)
Pharm Biol
, vol.48
, pp. 1302-1309
-
-
Li, C.T.1
Lin, C.H.2
Kao, T.Y.3
Wu, M.F.4
Yeh, C.S.5
Yeh, K.T.6
Ko, J.L.7
|