Trichosanthin Inhibits Breast Cancer Cell Proliferation in Both Cell Lines and Nude Mice by Promotion of Apoptosis

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Fang, Evandro Fei ^a,c   Zhang, Chris Zhi Yi ^b   Zhang, Lin ^a   Wong, Jack Ho ^a   Chan, Yau Sang ^a   Pan, Wen Liang ^a   Dan, Xiu Li ^a   Yin, Cui Ming ^a   Cho, Chi Hin ^a   Ng, Tzi Bun ^a  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^b SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^c NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 8; CASPASE 9; ESTROGEN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; TRICHOSANTHIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE ARREST; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG SCREENING; ENZYME ACTIVATION; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; TUMOR CELL DESTRUCTION; TUMOR VOLUME; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CASPASE 3; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; DNA FRAGMENTATION; ENZYME ACTIVATION; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; MAMMARY NEOPLASMS, ANIMAL; MEDICINE, CHINESE TRADITIONAL; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; PLANT EXTRACTS; TRICHOSANTHIN;

MUS MUSCULUS; TRICHOSANTHES KIRILOWII;

EID: 84866050965     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041592     Document Type: Article

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