3D bioprinting of BMSC-laden methacrylamide gelatin scaffolds with CBD-BMP2-collagen microfibers

Biofabrication

Volumn 7, Issue 4, 2015, Pages

  Du, Mingchun ^a,b   Chen, Bing ^a   Meng, Qingyuan ^a   Liu, Sumei ^a   Zheng, Xiongfei ^c   Zhang, Cheng ^c   Wang, Heran ^c   Li, Hongyi ^c   Wang, Nuo ^a   Dai, Jianwu ^a  

^a INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY   (China)

^b ZonHon Biopharma Institute   (China)

^c SHENYANG INSTITUTE OF AUTOMATION   (China)

Author keywords

3D bioprinting; BMSC; CBD BMP2 collagen microfiber; methacrylamide gelatin scaffold; osteogenic differentiation

Indexed keywords

3D PRINTERS; BONE; CELL CULTURE; CELLS; COLLAGEN; CYTOLOGY; PORE SIZE; PRINTING; STEM CELLS;

BIOPRINTING; BMSC; METHACRYLAMIDES; MICRO-FIBER; OSTEOGENIC DIFFERENTIATION;

SCAFFOLDS (BIOLOGY);

ACRYLAMIDE DERIVATIVE; BONE MORPHOGENETIC PROTEIN 2; COLLAGEN; GELATIN; HYDROGEL; METHACRYLAMIDE;

ANIMAL; BIOPRINTING; BONE DEVELOPMENT; CELL DIFFERENTIATION; CHEMISTRY; CYTOLOGY; DEVICES; DRUG EFFECTS; HYDROGEL; MESENCHYMAL STROMA CELL; OSTEOCYTE; PHARMACOLOGY; PIG; PROCEDURES; PROTEIN TERTIARY STRUCTURE; THREE DIMENSIONAL PRINTING; TISSUE SCAFFOLD;

ACRYLAMIDES; ANIMALS; BIOPRINTING; BONE MORPHOGENETIC PROTEIN 2; CELL DIFFERENTIATION; COLLAGEN; GELATIN; HYDROGEL; MESENCHYMAL STROMAL CELLS; OSTEOCYTES; OSTEOGENESIS; PRINTING, THREE-DIMENSIONAL; PROTEIN STRUCTURE, TERTIARY; SUS SCROFA; TISSUE SCAFFOLDS;

EID: 84954190873     PISSN: 17585082     EISSN: 17585090     Source Type: Journal    
DOI: 10.1088/1758-5090/7/4/044104     Document Type: Article

References (63)

1. Murphy S V and Atala A 2014 3D bioprinting of tissues and organs Nat. Biotechnol. 32 773-85
2. Nakamura M, Iwanaga S, Henmi C, Arai1 K and Nishiyama Y 2010 Biomatrices and biomaterials for future developments of bioprinting and biofabrication Biofabrication 2 014110
3. Zopf D A, Hollister S J, Nelson M E, Ohye R G and Green G E 2013 Bioresorbable airway splint created with a three-dimensional printer N. Engl. J. Med. 368 2043-5
4. Gauvin R, Parenteau-Bareil R, Dokmeci M R, Merryman W D and Khademhosseini A 2012 Hydrogels and microtechnologies for engineering the cellular microenvironment WIREs Nanomed. Nanobiotechnol. 4 235-46
5. Slaughter B V, Khurshid S S, Fisher O Z, Khademhosseini A and Peppas N A 2009 Hydrogels in regenerative medicine Adv. Mater. 21 3307-29
6. Hollister S J 2009 Scaffold design and manufacturing: from concept to clinic Adv. Mater. 21 3330-42
7. Sage E H 2001 Regulation of interactions between cells and extracellular matrix: a command performance on several stages J. Clin. Invest. 107 781-3
8. Boudreau N J and Jones P L 1999 Extracellular matrix and integrin signaling: the shape of things to come Biochem. J. 339 481-8
9. Lutolf M P and Hubbell J A 2005 Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering Nat. Biotechnol. 23 47-55
10. Chetprayoon P, Kadowaki K, Matsusaki M and Akashi M 2013 Survival and structural evaluations of three-dimensional tissues fabricated by the hierarchical cell manipulation technique Acta Biomater. 9 4698-706
11. Ingber D E, Mow V C, Butler D, Niklason L, Huard J, Mao J, Yannas I, Kaplan D and Vunjak-Novakovic G 2006 Tissue engineering and developmental biology: going biomimetic Tissue Eng. 12 3265-83
12. Malda J, Visser J, Melchels F P, Juengst T, Hennink W E, Dhert W J A, Groll J and Hutmacher D W 2013 25th anniversary article: engineering hydrogels for biofabrication Adv. Mater. 25 5011-28
13. Yang K, Lee J S, Kim J, Lee Y B, Shin H, Um S H, Kim J B, Park K I, Lee H and Cho S W 2012 Polydopamine-mediated surface modification of scaffold materials for human neural stem cell engineering Biomaterials 33 6952-64
14. Du M C et al 2013 Assembled 3D cell niches in chitosan hydrogel network to mimic extracellular matrix Colloids Surf. A 434 78-87
15. Du M C, Liang H, Mou C C, Li X R, Sun J, Zhuang Y, Xiao Z F, Chen B and Dai J W 2014 Regulation of human mesenchymal stem cells differentiation into chondrocytes in extracellular matrix-based hydrogel scaffolds Colloids Surf. B 114 316-23
16. Mi F L, Shyu S S, Peng C K, Wu Y B, Sung H W, Wang P S and Huang C C 2006 Fabrication of chondroitin sulfate-chitosan composite artificial extracellular matrix for stabilization of fibroblast growth factor J. Biomed. Mater. Res. 76A 1-15
17. Lin H, Zhao Y, Sun W, Chen B, Zhang J, Zhao W, Xiao Z and Dai J 2008 The effect of crosslinking heparin to demineralized bone matrix on mechanical strength and specific binding to human bone morphogenetic protein-2 Biomaterials 29 1189-97
18. Sun B, Chen B, Zhao Y, Sun W, Chen K, Zhang J, Wei Z, Xiao Z and Dai J 2009 Crosslinking heparin to collagen scaffolds for the delivery of human platelet-derived growth factor J. Biomed. Mater. Res. B 91 366-72
19. Mazue G, Newman A J, Scampini G, Dellatorre P, Hard G C, Iatropoulos M J, Williams G M and Bagnasco S M 1993 The histopathology of kidney changes in rats and monkeys following intravenous administration of massive doses of FCE-26184, human basic fibroblast growth factor Toxicol. Pathol. 21 490-501
20. Lee K Y, Peters M C and Mooney D J 2003 Comparison of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in SCID mice J. Control. Release 87 49-56
21. Xu X, Yee W C, Hwang P Y, Yu H, Wan A C, Gao S, Boon K L, Mao H Q, Leong K W and Wang S 2003 Peripheral nerve regeneration with sustained release of poly(phosphoester) microencapsulated nerve growth factor within nerve guide conduits Biomaterials 24 2405-12
22. Sohier J, Haan R E, de Groot K and Bezemer J M 2003 A novel method to obtain protein release from porous polymer scaffolds: emulsion coating J. Control. Release 87 57-68
23. Zhao W, Chen B, Li X, Lin H, Sun W, Zhao Y, Wang B, Zhao Y, Han Q and Dai J 2007 Vascularization and cellularization of collagen scaffolds incorporated with two different collagen-targeting human basic fibroblast growth factors J. Biomed. Mater. Res. A 82 630-6
24. Chen W et al 2010 Bladder regeneration by collagen scaffolds with collagen binding human basic fibroblast growth factor J. Urology 183 22432-9
25. Zhao Y, Chen B, Lin H, Sun W, Zhao W, Zhang J and Dai J 2009 The bone-derived collagen containing mineralized matrix for the loading of collagen-binding bone morphogenetic protein-2 J. Biomed. Mater. Res. A 88 725-34
26. Sun W, Lin H, Chen B, Zhao W, Zhao Y, Xiao Z and Dai J 2010 Collagen scaffolds loaded with collagen-binding NGF-β accelerate ulcer healing J. Biomed. Mater. Res. A 92 887-95
27. Han Q et al 2010 The promotion of neural regeneration in an extreme rat spinal cord injury model using a collagen scaffold containing a collagen binding neuroprotective protein and an EGFR neutralizing antibody Biomaterials 31 9212-20
28. Zhang J, Ding L, Zhao Y, Sun W, Chen B, Lin H, Wang X, Zhang L, Xu B and Dai J 2009 Collagen-targeting vascular endothelial growth factor improves cardiac performance after myocardial infarction Circulation 119 1776-84
29. Li X et al 2011 Regeneration of uterine horns in rats by collagen scaffolds loaded with collagen-binding human basic fibroblast growth factor Biomaterials 32 8172-81
30. Kolesky D B, Truby R L, Gladman A S, Busbee T A, Homan K A and Lewis J A 2014 3D bioprinting of vascularized, heterogeneous cell-laden tissue constructs Adv. Mater. 26 3124-30
31. Schuurman W, Levett P A, Pot M W, van Weeren P R, Dhert W J A, Hutmacher D W, Melchels F P W, Klein T J and Malda J 2013 Gelatin-methacrylamide hydrogels as potential biomaterials for fabrication of tissue-engineered cartilage constructs Macromol. Biosci. 13 551-61
32. Han S, Zhao Y, Xiao Z, Han J, Chen B, Chen L and Dai J 2012 The three-dimensional collagen scaffold improves the stemness of rat bone marrow mesenchymal stem cells J. Genet. Genomics 39 633-41
33. Iwami K, Noda T, Ishida K, Morishima K, Nakamura M and Umeda N 2010 Bio rapid prototyping by extruding/aspirating/refilling thermoreversible hydrogel Biofabrication 2 014108
34. Shor L, Güçeri S, Chang R, Gordon J, Kang Q, Hartsock L, An Y and Sun W 2009 Precision extruding deposition (PED) fabrication of polycaprolactone (PCL) scaffolds for bone tissue engineering Biofabrication 1 015003
35. Peltola S M, Melchels F P, Grijpma D W and Kellomaki M 2008 A review of rapid prototyping techniques for tissue engineering purposes Ann. Med. 40 268-80
36. Chang C C, Boland E D, Williams S K and Hoying J B 2011 Direct-write bioprinting three-dimensional biohybrid systems for future regenerative therapies J. Biomed. Mater. Res. B 98 160-70
37. Jakab K, Damon B, Neagu A, Kachurin A and Forgacs G 2006 Three-dimensional tissue constructs built by bioprinting Biorheology 43 509-13
38. Visser J, Peters B, Burger T J, Boomstra J, Dhert W J, Melchels F P and Malda J 2013 Biofabrication of multi-material anatomically shaped tissue constructs Biofabrication 5 035007
39. Cohen D L, Malone E, Lipson H and Bonassar L J 2006 Direct freeform fabrication of seeded hydrogels in arbitrary geometries Tissue Eng. 12 1325-35
40. Lee S S, Huang B J, Kaltz S R, Sur S, Newcomb C J, Stock S R, Shah R N and Stupp S I 2013 Bone regeneration with low dose BMP-2 amplified by biomimetic supramolecular nanofibers within collagen scaffolds Biomaterials 34 452-9
41. Haidar Z S, Hamdy R C and Tabrizian M 2009 Delivery of recombinant bone morphogenetic proteins for bone regeneration and repair: A. Current challenges in BMP delivery Biotechnol. Lett. 31 1817-24
42. Calori G M, Donati D, Di Bella C and Tagliabue L 2009 Bone morphogenetic proteins and tissue engineering: future directions Injury 40 S67-76 (Suppl 3)
43. Xiong L, Zeng J, Yao A, Tu Q, Li J, Yan L and Tang Z 2015 BMP2-loaded hollow hydroxyapatite microspheres exhibit enhanced osteoinduction and osteogenicity in large bone defects Int. J. Nanomedicine 10 517-26
44. McKay W F, Peckham S M and Badura J M 2007 A comprehensive clinical review of recombinant human bone morphogenetic protein-2 (INFUSE Bone Graft) Int. Orthop. 31 729-34
45. Murphy S V, Skardal A and Atala A 2013 Evaluation of hydrogels for bio-printing applications J. Biomed. Mater. Res. A 101 272-84
46. Hsu W K and Wang J C 2008 The use of bone morphogenetic protein in spine fusion Spine J. 8 419-25
47. Jones A L, Bucholz R W, Bosse M J, Mirza S K, Lyon T R, Webb L X, Pollak A N, Golden J D and Valentin-Opran A 2006 Recombinant human BMP-2 and allograft compared with autogenous bone graft for reconstruction of diaphyseal tibial fractures with cortical defects. A randomized, controlled trial J. Bone Joint Surg. Am. 88 1431-41
48. Haidar Z S, Hamdy R C and Tabrizian M 2009 Delivery of recombinant bone morphogenetic proteins for bone regeneration and repair: B. Delivery systems for BMPs in orthopaedic and craniofacial tissue engineering Biotechnol. Lett. 31 1825-35
49. Nagel T and Kelly D J 2013 The composition of engineered cartilage at the time of implantation determines the likelihood of regenerating tissue with a normal collagen architecture Tissue Eng. A 19 824-33
50. Williams D F 2008 On the mechanisms of biocompatibility Biomaterials 29 2941-53
51. Hunt N C and Grover L M 2010 Cell encapsulation using biopolymer gels for regenerative medicine Biotechnol. Lett. 32 733-42
52. Schuurman W, Levett P A, Pot M W, van Weeren P R, Dhert W J, Hutmacher D W, Melchels F P, Klein T J and Malda J 2013 Gelatin-methacrylamide hydrogels as potential biomaterials for fabrication of tissue-engineered cartilage constructs Macromol. Biosci. 13 551-61
53. Marquass B, Somerson J S, Hepp P, Aigner T, Schwan S, Bader A, Josten C, Zscharnack M and Schulz R M 2010 A novel MSC-seeded triphasic construct for the repair of osteochondral defects J. Orthop. Res. 28 1586-99
54. Park J S, Yang H J, Woo D G, Yang H N, Na K and Park K H 2010 Chondrogenic differentiation of mesenchymal stem cells embedded in a scaffold by long-term release of TGF-β3 complexed with chondroitin sulfate J. Biomed. Mater. Res. A 92 806-16
55. Richter W 2009 Mesenchymal stem cells and cartilage in situ regeneration J. Intern. Med. 266 390-405
56. Tuan R S 2006 Stemming cartilage degeneration: adult mesenchymal stem cells as a cell source for articular cartilage tissue engineering Arthritis Rheum. 54 3075-8
57. Sykaras N and Opperman L A 2003 Bone morphogenetic proteins (BMPs): how do they function and what can they offer the clinician ? J. Oral Sci. 45 57-73
58. Vladimirov B S and Dimitrov S A 2004 Growth factors-importance and possibilities for enhancement of the healing process in bone fractures Folia Med. 46 11-7
59. Chen B, Lin H, Wang J, Zhao Y, Wang B, Zhao W, Sun W and Dai J 2007 Homogeneous osteogenesis and bone regeneration by demineralized bone matrix loading with collagen-targeting bone morphogenetic protein-2 Biomaterials 28 1027-35
60. Becerra J, Andrades J A, Santamaria J A, Cifuentes M and Guerado E 2001 Bone regeneration, cell therapy and tissue engineering Med. Clin. 116 23-34
61. Hall F L, Kaiser A, Liu L, Chen Z H, Hu J, Nimni M E, Beart R W and Gordon E M 2000 Design, expression, and renaturation of a lesion-targeted recombinant epidermal growth factor-von Willebrand factor fusion protein: efficacy in an animal model of experimental colitis Int. J. Mol. Med. 6 635-43
62. Nimni M E 1997 Polypeptide growth factors: targeted delivery systems Biomaterials 18 1201-25
63. Komori T 2006 Regulation of osteoblast differentiation by transcription factors J. Cell Biochem. 99 1233-9