The promotion of neural regeneration in an extreme rat spinal cord injury model using a collagen scaffold containing a collagen binding neuroprotective protein and an EGFR neutralizing antibody

Biomaterials

Volumn 31, Issue 35, 2010, Pages 9212-9220

  Han, Qianqian ^a,b   Jin, Wei ^c   Xiao, Zhifeng ^a   Ni, Hongbin ^c   Wang, Jinhuan ^d   Kong, Jie ^c   Wu, Jun ^c   Liang, Weibang ^c   Chen, Lei ^a   Zhao, Yannan ^a   Chen, Bing ^a   Dai, Jianwu ^a  

^a INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^d Huanhu Hospital   (China)

Author keywords

Collagen; EGFR neutralizing antibody; Nerve regeneration; Spinal cord injury

Indexed keywords

AXON REGENERATION; CHONDROITIN SULFATE PROTEOGLYCANS; COLLAGEN BINDING; COLLAGEN BINDING DOMAIN; COLLAGEN SCAFFOLDS; ELECTRICAL TRANSMISSION; EPIDERMAL GROWTH FACTOR RECEPTORS; FUNCTIONAL DEVICES; GLIAL SCAR; GROWTH INHIBITOR; INJURED SPINAL CORDS; NERVE REGENERATION; NEURAL REGENERATION; NEUROPROTECTIVE EFFECTS; NEUTRALIZING ANTIBODIES; RAT SPINAL CORD; SIGNALING PATHWAYS; SPINAL CORD INJURY; SPINAL CORDS;

BIOMATERIALS; CROSSLINKING; DOSIMETRY; MONOCLONAL ANTIBODIES; PATIENT REHABILITATION; SCAFFOLDS; SIGNALING; SULFUR COMPOUNDS; TISSUE;

COLLAGEN;

BRAIN DERIVED NEUROTROPHIC FACTOR; COLLAGEN; COLLAGEN BINDING PROTEIN; DRUG VEHICLE; EPIDERMAL GROWTH FACTOR RECEPTOR; LINEAR ORDERED COLLAGEN SCAFFOLD; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 151 IGG; TISSUE SCAFFOLD; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; CROSS LINKING; ENZYME LINKED IMMUNOSORBENT ASSAY; EVOKED SOMATOSENSORY RESPONSE; GLIA; IMMUNOHISTOCHEMISTRY; MALE; NERVE REGENERATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PRODUCT DEVELOPMENT; RAT; SPINAL CORD INJURY; TREATMENT OUTCOME;

ANIMALS; ANIMALS, NEWBORN; ANTIBODIES, NEUTRALIZING; ASTROCYTES; BRAIN-DERIVED NEUROTROPHIC FACTOR; COLLAGEN; ELECTROPHYSIOLOGY; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; MALE; MYELIN SHEATH; NERVE REGENERATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, EPIDERMAL GROWTH FACTOR; SPINAL CORD INJURIES; TISSUE SCAFFOLDS;

RATTUS;

EID: 77957942173     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.08.040     Document Type: Article

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