Herpes simplex virus 1 (HSV-1) and HSV-2 mediate species-specific modulations of programmed necrosis through the viral ribonucleotide reductase large subunit R1

Journal of Virology

Volumn 90, Issue 2, 2016, Pages 1088-1095

  Yu, Xiaoliang ^a   Li, Yun ^a   Chen, Qin ^a   Su, Chenhe ^b   Zhang, Zili ^a   Yang, Chengkui ^a   Hu, Zhilin ^a   Hou, Jue ^a   Zhou, Jinying ^a   Gong, Ling ^a   Jiang, Xuejun ^c   Zheng, Chunfu ^b,d   He, Sudan ^a  

^a MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

^b SOOCHOW UNIVERSITY   (China)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DOUBLE STRANDED RNA; MLKL PROTEIN; PROTEIN KINASE; RECEPTOR INTERACTING PROTEIN KINASE 1; RECEPTOR INTERACTING PROTEIN KINASE 3; RIBONUCLEOTIDE REDUCTASE; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DEFENSE MECHANISM; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HOST RESISTANCE; HUMAN; HUMAN CELL; NECROPTOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS REPLICATION; ANIMAL; CELL LINE; COMPARATIVE STUDY; HOST PATHOGEN INTERACTION; IMMUNOLOGY; METABOLISM; MOUSE; NECROSIS; PHYSIOLOGY;

ANIMALS; CELL LINE; HERPESVIRUS 1, HUMAN; HERPESVIRUS 2, HUMAN; HOST-PATHOGEN INTERACTIONS; HUMANS; MICE; NECROSIS; RIBONUCLEOTIDE REDUCTASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84954115107     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02446-15     Document Type: Article

References (29)

1. Sridharan H, Upton JW. 2014. Programmed necrosis in microbial pathogenesis. Trends Microbiol 22:199-207. http://dx.doi.org/10.1016/j.tim.2014.01.005.
2. Han J, Zhong CQ, Zhang DW. 2011. Programmed necrosis: backup to and competitor with apoptosis in the immune system. Nat Immunol 12: 1143-1149. http://dx.doi.org/10.1038/ni.2159.
3. Moriwaki K, Chan FK. 2013. RIP3: a molecular switch for necrosis and inflammation. Genes Dev 27:1640-1649. http://dx.doi.org/10.1101/gad.223321.113.
4. Degterev A, Huang Z, Boyce M, Li Y, Jagtap P, Mizushima N, Cuny GD, Mitchison TJ, Moskowitz MA, Yuan J. 2005. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 1:112-119. http://dx.doi.org/10.1038/nchembio711.
5. Holler N, Zaru R, Micheau O, Thome M, Attinger A, Valitutti S, Bodmer JL, Schneider P, Seed B, Tschopp J. 2000. Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol 1:489-495. http://dx.doi.org/10.1038/82732.
6. Declercq W, Vanden Berghe T, Vandenabeele P. 2009. RIP kinases at the crossroads of cell death and survival. Cell 138:229-232. http://dx.doi.org/10.1016/j.cell.2009.07.006.
7. Cho YS, Challa S, Moquin D, Genga R, Ray TD, Guildford M, Chan FK. 2009. Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 137: 1112-1123. http://dx.doi.org/10.1016/j.cell.2009.05.037.
8. He S, Wang L, Miao L, Wang T, Du F, Zhao L, Wang X. 2009. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell 137:1100-1111. http://dx.doi.org/10.1016/j.cell.2009.05.021.
9. Zhang DW, Shao J, Lin J, Zhang N, Lu BJ, Lin SC, Dong MQ, Han J. 2009. RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 325:332-336. http://dx.doi.org/10.1126/science.1172308.
10. Sun X, Yin J, Starovasnik MA, Fairbrother WJ, Dixit VM. 2002. Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3. J Biol Chem 277:9505-9511. http://dx.doi.org/10.1074/jbc.M109488200.
11. Moquin DM, McQuade T, Chan FK. 2013. CYLD deubiquitinates RIP1 in the TNFα-induced necrosome to facilitate kinase activation and programmed necrosis. PLoS One 8:e76841. http://dx.doi.org/10.1371/journal.pone.0076841.
12. Hitomi J, Christofferson DE, Ng A, Yao J, Degterev A, Xavier RJ, Yuan J. 2008. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 135:1311-1323. http://dx.doi.org/10.1016/j.cell.2008.10.044.
13. Zhao J, Jitkaew S, Cai Z, Choksi S, Li Q, Luo J, Liu ZG. 2012. Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis. Proc Natl Acad Sci U S A 109:5322-5327. http://dx.doi.org/10.1073/pnas.1200012109.
14. Sun L, Wang H, Wang Z, He S, Chen S, Liao D, Wang L, Yan J, Liu W, Lei X, Wang X. 2012. Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell 148:213-227. http://dx.doi.org/10.1016/j.cell.2011.11.031.
15. Wang H, Sun L, Su L, Rizo J, Liu L, Wang LF, Wang FS, Wang X. 2014. Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3. Mol Cell 54:133-146. http://dx.doi.org/10.1016/j.molcel.2014.03.003.
16. Cai Z, Jitkaew S, Zhao J, Chiang HC, Choksi S, Liu J, Ward Y, Wu LG, Liu ZG. 2014. Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis. Nat Cell Biol 16:55-65. http://dx.doi.org/10.1038/ncb2883.
17. Chen X, Li W, Ren J, Huang D, He WT, Song Y, Yang C, Li W, Zheng X, Chen P, Han J. 2014. Translocation of mixed lineage kinase domainlike protein to plasma membrane leads to necrotic cell death. Cell Res 24:105-121. http://dx.doi.org/10.1038/cr.2013.171.
18. Kawai T, Akira S. 2011. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 34:637-650. http://dx.doi.org/10.1016/j.immuni.2011.05.006.
19. Kaiser WJ, Sridharan H, Huang C, Mandal P, Upton JW, Gough PJ, Sehon CA, Marquis RW, Bertin J, Mocarski ES. 2013. Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL. J Biol Chem 288:31268-31279. http://dx.doi.org/10.1074/jbc.M113.462341.
20. He S, Liang Y, Shao F, Wang X. 2011. Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway. Proc Natl Acad Sci U S A 108:20054-20059. http://dx.doi.org/10.1073/pnas.1116302108.
21. Dobbelstein M, Shenk T. 1996. Protection against apoptosis by the vaccinia virus SPI-2 (B13R) gene product. J Virol 70:6479-6485.
22. Kettle S, Alcami A, Khanna A, Ehret R, Jassoy C, Smith GL. 1997. Vaccinia virus serpin B13R (SPI-2) inhibits interleukin-1beta-converting enzyme and protects virus-infected cells from TNF-and Fas-mediated apoptosis, but does not prevent IL-1beta-induced fever. J Gen Virol 78: 677-685. http://dx.doi.org/10.1099/0022-1317-78-3-677.
23. Upton JW, Kaiser WJ, Mocarski ES. 2010. Virus inhibition of RIP3-dependent necrosis. Cell Host Microbe 7:302-313. http://dx.doi.org/10.1016/j.chom.2010.03.006.
24. Upton JW, Kaiser WJ, Mocarski ES. 2012. DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA. Cell Host Microbe 11:290-297. http://dx.doi.org/10.1016/j.chom.2012.01.016.
25. Wang X, Li Y, Liu S, Yu X, Li L, Shi C, He W, Li J, Xu L, Hu Z, Yu L, Yang Z, Chen Q, Ge L, Zhang Z, Zhou B, Jiang X, Chen S, He S. 2014. Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense. Proc Natl Acad Sci U S A 111:15438-15443. http://dx.doi.org/10.1073/pnas.1412767111.
26. Huang Z, Wu SQ, Liang Y, Zhou X, Chen W, Li L, Wu J, Zhuang Q, Chen C, Li J, Zhong CQ, Xia W, Zhou R, Zheng C, Han J. 2015. RIP1/RIP3 binding to HSV-1 ICP6 initiates necroptosis to restrict virus propagation in mice. Cell Host Microbe 17:229-242. http://dx.doi.org/10.1016/j.chom.2015.01.002.
27. Wang Z, Jiang H, Chen S, Du F, Wang X. 2012. The mitochondrial phosphatase PGAM5 functions at the convergent point of multiple necrotic death pathways. Cell 148:228-243. http://dx.doi.org/10.1016/j.cell.2011.11.030.
28. Guo H, Omoto S, Harris PA, Finger JN, Bertin J, Gough PJ, Kaiser WJ, Mocarski ES. 2015. Herpes simplex virus suppresses necroptosis in human cells. Cell Host Microbe 17:243-251. http://dx.doi.org/10.1016/j.chom.2015.01.003.
29. Chen W, Zhou Z, Li L, Zhong CQ, Zheng X, Wu X, Zhang Y, Ma H, Huang D, Li W, Xia Z, Han J. 2013. Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling. J Biol Chem 288:16247-16261. http://dx.doi.org/10.1074/jbc.M112.435545.