Deletion of monoglyceride lipase in astrocytes attenuates lipopolysaccharide-induced neuroinflammation

Journal of Biological Chemistry

Volumn 291, Issue 2, 2016, Pages 913-923

  Grabner, Gernot F ^a   Eichmann, Thomas O ^a   Wagner, Bernhard ^b   Gao, Yuanqing ^c   Farzi, Aitak ^d   Taschler, Ulrike ^a   Radner, Franz P W ^a   Schweiger, Martina ^a   Lass, Achim ^a   Holzer, Peter ^d   Zinser, Erwin ^b   Tschöp, Matthias H ^c   Yi, Chun Xia ^c,e   Zimmermann, Robert ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b FH JOANNEUM UNIVERSITY OF APPLIED SCIENCES   (Austria)

^c Helmholtz Center Munich   (Germany)

^d MEDICAL UNIVERSITY OF GRAZ   (Austria)

^e ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG PRODUCTS; LIPIDS; MAMMALS; METABOLISM;

ANTI-INFLAMMATORIES; ANTI-INFLAMMATORY EFFECTS; BENEFICIAL EFFECTS; CANNABINOID RECEPTORS; LIPOPOLYSACCHARIDES; METABOLIC FUNCTION; NEUROINFLAMMATION; PROSTAGLANDIN SYNTHESIS;

ASCORBIC ACID;

2 ARACHIDONOYLGLYEROL; ACYLGLYCEROL LIPASE; ARACHIDONIC ACID; CANNABINOID RECEPTOR; ENDOCANNABINOID; LIPOPOLYSACCHARIDE; PROSTAGLANDIN E2; RIMONABANT; UNCLASSIFIED DRUG; ACYLGLYCEROL; ARACHIDONIC ACID DERIVATIVE; CANNABINOID 1 RECEPTOR; CYTOKINE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLYCERYL 2-ARACHIDONATE;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTE; BRAIN METABOLISM; CELL SPECIFICITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME INHIBITION; FEMALE; GENE DELETION; MALE; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RECEPTOR DOWN REGULATION; ANIMAL; ANTIBODY SPECIFICITY; BRAIN; C57BL MOUSE; ENZYMOLOGY; INFLAMMATION; KNOCKOUT MOUSE; METABOLISM; MICROGLIA; NERVOUS SYSTEM; PATHOLOGY;

ANIMALS; ARACHIDONIC ACIDS; ASTROCYTES; BEHAVIOR, ANIMAL; BRAIN; CYTOKINES; ENDOCANNABINOIDS; FEMALE; GENE DELETION; GLIAL FIBRILLARY ACIDIC PROTEIN; GLYCERIDES; INFLAMMATION; LIPOPOLYSACCHARIDES; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; MONOACYLGLYCEROL LIPASES; NERVOUS SYSTEM; ORGAN SPECIFICITY; RECEPTOR, CANNABINOID, CB1;

EID: 84954098376     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.683615     Document Type: Article

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