메뉴 건너뛰기




Volumn 6, Issue , 2016, Pages

Molecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators

Author keywords

[No Author keywords available]

Indexed keywords

1-PALMITOYL-2-ARACHIDONYL-3-PHOSPHORYLCHOLINE; FREE RADICAL; HYDROGEN; LINOLEIC ACID; PHOSPHATIDYLCHOLINE; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTOME;

EID: 84954095242     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep18971     Document Type: Article
Times cited : (96)

References (45)
  • 1
    • 34250021071 scopus 로고    scopus 로고
    • Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals
    • Ohsawa I., et al. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat. Med. 13, 688-694 (2007
    • (2007) Nat. Med , vol.13 , pp. 688-694
    • Ohsawa, I.1
  • 2
    • 84863648677 scopus 로고    scopus 로고
    • Molecular hydrogen protects chondrocytes from oxidative stress and indirectly alters gene expressions through reducing peroxynitrite derived from nitric oxide
    • Hanaoka T., Kamimura N., Yokota T., Takai S., & Ohta S. Molecular hydrogen protects chondrocytes from oxidative stress and indirectly alters gene expressions through reducing peroxynitrite derived from nitric oxide. Med. Gas Res. 1, 18 (2011).
    • (2011) Med. Gas Res , vol.1 , Issue.18
    • Hanaoka, T.1    Kamimura, N.2    Yokota, T.3    Takai, S.4    Ohta, S.5
  • 3
    • 34547768785 scopus 로고    scopus 로고
    • Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress
    • Fukuda K., et al. Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress. Biochem. Biophys. Res. Commun. 361, 670-674 (2007
    • (2007) Biochem. Biophys. Res. Commun , vol.361 , pp. 670-674
    • Fukuda, K.1
  • 4
    • 45949085302 scopus 로고    scopus 로고
    • Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia-reperfusion injury
    • Hayashida K., et al. Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia-reperfusion injury. Biochem. Biophys. Res. Commun. 373, 30-35 (2008
    • (2008) Biochem. Biophys. Res. Commun , vol.373 , pp. 30-35
    • Hayashida, K.1
  • 5
    • 84918520486 scopus 로고    scopus 로고
    • Hydrogen inhalation during normoxic resuscitation improves neurological outcome in a rat model of cardiac arrest independent of targeted temperature management
    • Hayashida K., et al. Hydrogen Inhalation During Normoxic Resuscitation Improves Neurological Outcome in a Rat Model of Cardiac Arrest, Independent of Targeted Temperature Management. Circulation. 130, 2173-2180 (2014
    • (2014) Circulation , vol.130 , pp. 2173-2180
    • Hayashida, K.1
  • 6
    • 80052226753 scopus 로고    scopus 로고
    • Recent progress toward hydrogen medicine: Potential of molecular hydrogen for preventive and therapeutic applications
    • Ohta S. Recent progress toward hydrogen medicine: potential of molecular hydrogen for preventive and therapeutic applications. Curr. Pharm. Des. 17, 2241-2252 (2011
    • (2011) Curr. Pharm. des , vol.17 , pp. 2241-2252
    • Ohta, S.1
  • 7
    • 84906934199 scopus 로고    scopus 로고
    • Molecular hydrogen as a preventive and therapeutic medical gas: Initiation, development and potential of hydrogen medicine
    • Ohta S. Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine. Pharmacol. Ther. 144, 1-11 (2014
    • (2014) Pharmacol. Ther , vol.144 , pp. 1-11
    • Ohta, S.1
  • 8
    • 84879602817 scopus 로고    scopus 로고
    • Pilot study of h 2) therapy in Parkinson's disease: A randomized double-blind placebo-controlled trial
    • Yoritaka A., et al. Pilot study of H(2) therapy in Parkinson's disease: a randomized double-blind placebo-controlled trial. Mov. Disord. 28, 836-839 (2013
    • (2013) Mov. Disord , vol.28 , pp. 836-839
    • Yoritaka, A.1
  • 9
    • 84903194951 scopus 로고    scopus 로고
    • Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: A randomized, double-blind, placebo-controlled pilot study
    • Ishibashi T., et al. Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: a randomized, double-blind, placebo-controlled pilot study. Int. Immunopharmacol. 21, 468-473 (2014
    • (2014) Int. Immunopharmacol , vol.21 , pp. 468-473
    • Ishibashi, T.1
  • 10
    • 84888250631 scopus 로고    scopus 로고
    • Oral 'hydrogen water' induces neuroprotective ghrelin secretion in mice
    • Matsumoto A., et al. Oral 'hydrogen water' induces neuroprotective ghrelin secretion in mice. Sci. Rep. 3, 3273 (2013
    • (2013) Sci. Rep , vol.3 , pp. 3273
    • Matsumoto, A.1
  • 11
    • 79959655309 scopus 로고    scopus 로고
    • Molecular hydrogen improves obesity and diabetes by inducing hepatic fgf21 and stimulating energy metabolism in db/db mice
    • Kamimura N., Nishimaki K., Ohsawa I., & Ohta S. Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice. Obesity. 19, 1396-1403 (2011
    • (2011) Obesity , vol.19 , pp. 1396-1403
    • Kamimura, N.1    Nishimaki, K.2    Ohsawa, I.3    Ohta, S.4
  • 12
    • 84887856794 scopus 로고    scopus 로고
    • Molecular hydrogen: New antioxidant and anti-inflammatory therapy for rheumatoid arthritis and related diseases
    • Ishibashi T. Molecular hydrogen: new antioxidant and anti-inflammatory therapy for rheumatoid arthritis and related diseases. Curr. Pharm. Des. 19, 6375-6381 (2013
    • (2013) Curr. Pharm. des , vol.19 , pp. 6375-6381
    • Ishibashi, T.1
  • 13
    • 0028959042 scopus 로고
    • Mechanisms of free radical oxidation of unsaturated lipids
    • Porter N. A., Caldwell S. E., & Mills K. A. Mechanisms of free radical oxidation of unsaturated lipids. Lipids. 30, 277-290 (1995
    • (1995) Lipids , vol.30 , pp. 277-290
    • Porter, N.A.1    Caldwell, S.E.2    Mills, K.A.3
  • 14
    • 0036556717 scopus 로고    scopus 로고
    • Hydroxy alkenal phospholipids regulate inflammatory functions of endothelial cells
    • Subbanagounder G., et al. Hydroxy alkenal phospholipids regulate inflammatory functions of endothelial cells. Vascul. Pharmacol. 38, 201-209 (2002
    • (2002) Vascul. Pharmacol , vol.38 , pp. 201-209
    • Subbanagounder, G.1
  • 15
    • 77949618571 scopus 로고    scopus 로고
    • Generation and biological activities of oxidized phospholipids
    • Bochkov V. N., et al. Generation and biological activities of oxidized phospholipids. Antioxid. Redox Signal. 12, 1009-1059 (2010
    • (2010) Antioxid. Redox Signal , vol.12 , pp. 1009-1059
    • Bochkov, V.N.1
  • 16
    • 0036096132 scopus 로고    scopus 로고
    • Oxidized phospholipids stimulate tissue factor expression in human endothelial cells via activation of erk/ egr-1 and ca(+ + )/nfat
    • Bochkov V. N., et al. Oxidized phospholipids stimulate tissue factor expression in human endothelial cells via activation of ERK/ EGR-1 and Ca(+ + )/NFAT. Blood. 99, 199-206 (2002
    • (2002) Blood , vol.99 , pp. 199-206
    • Bochkov, V.N.1
  • 17
    • 28844451017 scopus 로고    scopus 로고
    • Identification of 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids as ligands of the g protein-coupled receptor g2a
    • Obinata H., Hattori T., Nakane S., Tatei K., & Izumi T. Identification of 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids as ligands of the G protein-coupled receptor G2A. J. Biol. Chem. 280, 40676-40683 (2005
    • (2005) J. Biol. Chem , vol.280 , pp. 40676-40683
    • Obinata, H.1    Hattori, T.2    Nakane, S.3    Tatei, K.4    Izumi, T.5
  • 18
    • 0033789652 scopus 로고    scopus 로고
    • Determinants of bioactivity of oxidized phospholipids specific oxidized fatty acyl groups at the sn-2 position
    • Subbanagounder G., et al. Determinants of bioactivity of oxidized phospholipids. Specific oxidized fatty acyl groups at the sn-2 position. Arterioscler. Thromb. Vasc. Biol. 20, 2248-2254 (2000
    • (2000) Arterioscler. Thromb. Vasc. Biol , vol.20 , pp. 2248-2254
    • Subbanagounder, G.1
  • 19
    • 84883138799 scopus 로고    scopus 로고
    • Nuclear calcium signalling in the regulation of brain function
    • Bading H. Nuclear calcium signalling in the regulation of brain function. Nat. Rev. Neurosci. 14, 593-608 (2013
    • (2013) Nat. Rev. Neurosci , vol.14 , pp. 593-608
    • Bading, H.1
  • 20
    • 0141483523 scopus 로고    scopus 로고
    • Transcriptional regulation by calcium, calcineurin, and nfat
    • Hogan P. G., Chen L., Nardone J., & Rao A. Transcriptional regulation by calcium, calcineurin, and NFAT. Genes Dev. 17, 2205-2232 (2003
    • (2003) Genes Dev , vol.17 , pp. 2205-2232
    • Hogan, P.G.1    Chen, L.2    Nardone, J.3    Rao, A.4
  • 21
    • 84890125992 scopus 로고    scopus 로고
    • Biomarkers of lipid peroxidation in clinical material
    • Niki E. Biomarkers of lipid peroxidation in clinical material. Biochim. Biophys. Acta. 1840, 809-817 (2014
    • (2014) Biochim. Biophys. Acta , vol.1840 , pp. 809-817
    • Niki, E.1
  • 22
    • 84863989944 scopus 로고    scopus 로고
    • Chemistry of phospholipid oxidation
    • Reis A., & Spickett C. M. Chemistry of phospholipid oxidation. Biochim. Biophys. Acta. 1818, 2374-2387 (2012
    • (2012) Biochim. Biophys. Acta , vol.1818 , pp. 2374-2387
    • Reis, A.1    Spickett, C.M.2
  • 23
    • 79958838317 scopus 로고    scopus 로고
    • Analysis of 2,2' -Azobis (2-Amidinopropane) dihydrochloride degradation and hydrolysis in aqueous solutions
    • Werber J., Wang Y. J., Milligan M., Li X., & Ji J. A. Analysis of 2,2' -Azobis (2-Amidinopropane) dihydrochloride degradation and hydrolysis in aqueous solutions. J. Pharm. Sci. 100, 3307-3315 (2011
    • (2011) J. Pharm. Sci , vol.100 , pp. 3307-3315
    • Werber, J.1    Wang, Y.J.2    Milligan, M.3    Li, X.4    Ji, J.A.5
  • 24
    • 34249991689 scopus 로고    scopus 로고
    • Oxidized phospholipids: From molecular properties to disease
    • Fruhwirth G. O., Loidl A., & Hermetter A. Oxidized phospholipids: from molecular properties to disease. Biochim. Biophys. Acta. 1772, 718-736 (2007
    • (2007) Biochim. Biophys. Acta , vol.1772 , pp. 718-736
    • Fruhwirth, G.O.1    Loidl, A.2    Hermetter, A.3
  • 25
    • 84865246069 scopus 로고    scopus 로고
    • A novel fluorescent probe with high sensitivity and selective detection of lipid hydroperoxides in cells
    • Yamanaka K., et al A novel fluorescent probe with high sensitivity and selective detection of lipid hydroperoxides in cells. RSC Advances 2. 7894 (2012
    • (2012) RSC Advances , vol.2 , pp. 7894
    • Yamanaka, K.1
  • 26
    • 84878642631 scopus 로고    scopus 로고
    • Hydrogen gas reduces hyperoxic lung injury via the nrf2 pathway in vivo
    • Kawamura T., et al. Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo. Am. J. Physiol. Lung Cell. Mol. Physiol. 304, L646-656 (2013
    • (2013) Am. J. Physiol. Lung Cell. Mol. Physiol , vol.304 , pp. L646-656
    • Kawamura, T.1
  • 28
    • 84924058315 scopus 로고    scopus 로고
    • Molecular hydrogen as a novel antioxidant: Overview of the advantages of hydrogen for medical applications
    • Ohta S. Molecular hydrogen as a novel antioxidant: overview of the advantages of hydrogen for medical applications. Methods Enzymol. 555, 289-317 (2015
    • (2015) Methods Enzymol , vol.555 , pp. 289-317
    • Ohta, S.1
  • 29
    • 78149282656 scopus 로고    scopus 로고
    • Hydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model
    • Xie K., et al. Hydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model. Shock. 34, 495-501 (2010
    • (2010) Shock , vol.34 , pp. 495-501
    • Xie, K.1
  • 30
    • 51849085219 scopus 로고    scopus 로고
    • Hydrogen inhalation ameliorates oxidative stress in transplantation induced intestinal graft injury
    • Buchholz B. M., et al. Hydrogen inhalation ameliorates oxidative stress in transplantation induced intestinal graft injury. Am. J. Transplant. 8, 2015-2024 (2008
    • (2008) Am. J. Transplant , vol.8 , pp. 2015-2024
    • Buchholz, B.M.1
  • 31
    • 84880553392 scopus 로고    scopus 로고
    • H 2) gas improves functional outcome after cardiac arrest to an extent comparable to therapeutic hypothermia in a rat model
    • Hayashida K., et al. H(2) gas improves functional outcome after cardiac arrest to an extent comparable to therapeutic hypothermia in a rat model. J. Am. Heart Assoc. 1, e003459 (2012
    • (2012) J. Am. Heart Assoc , vol.1 , pp. e003459
    • Hayashida, K.1
  • 32
    • 73349123786 scopus 로고    scopus 로고
    • Oral hydrogen water prevents chronic allograft nephropathy in rats
    • Cardinal J. S.et al. Oral hydrogen water prevents chronic allograft nephropathy in rats. Kidney Int. 77, 101-109 (2010
    • (2010) Kidney Int , vol.77 , pp. 101-109
    • Cardinal, J.S.1
  • 33
    • 84884202988 scopus 로고    scopus 로고
    • Acteoside inhibits type iota allergy through the down-regulation of ca/ nfat and jnk mapk signaling pathways in basophilic cells
    • Motojima H., Villareal M. O., Iijima R., Han J., & Isoda H. Acteoside inhibits type Iota allergy through the down-regulation of Ca/ NFAT and JNK MAPK signaling pathways in basophilic cells. J. Nat. Med. 67, 790-798 (2013
    • (2013) J. Nat. Med , vol.67 , pp. 790-798
    • Motojima, H.1    Villareal, M.O.2    Iijima, R.3    Han, J.4    Isoda, H.5
  • 34
    • 84857840998 scopus 로고    scopus 로고
    • Molecular diagnostics of calcineurin-related pathologies
    • Musson R. E., Cobbaert C. M., & Smit N. P. Molecular diagnostics of calcineurin-related pathologies. Clin. Chem. 58, 511-522 (2012
    • (2012) Clin. Chem , vol.58 , pp. 511-522
    • Musson, R.E.1    Cobbaert, C.M.2    Smit, N.P.3
  • 35
    • 79960560345 scopus 로고    scopus 로고
    • Molecular hydrogen inhibits lipopolysaccharide/interferon gamma-induced nitric oxide production through modulation of signal transduction in macrophages
    • Itoh T., et al. Molecular hydrogen inhibits lipopolysaccharide/interferon gamma-induced nitric oxide production through modulation of signal transduction in macrophages. Biochem. Biophys. Res. Commun. 411, 143-149 (2011
    • (2011) Biochem. Biophys. Res. Commun , vol.411 , pp. 143-149
    • Itoh, T.1
  • 36
    • 33751577221 scopus 로고    scopus 로고
    • Calcineurin regulates nfat-dependent inos expression and protection of cardiomyocytes: Cooperation with src tyrosine kinase
    • Obasanjo-Blackshire K., et al. Calcineurin regulates NFAT-dependent iNOS expression and protection of cardiomyocytes: cooperation with Src tyrosine kinase. Cardiovasc. Res. 71, 672-683 (2006
    • (2006) Cardiovasc. Res , vol.71 , pp. 672-683
    • Obasanjo-Blackshire, K.1
  • 37
    • 84886839508 scopus 로고    scopus 로고
    • Treatment with hydrogen molecules prevents rankl-induced osteoclast differentiation associated with inhibition of ros formation and inactivation of mapk akt and nf-kappa b pathways in murine raw264.7 cells
    • Li D. Z., Zhang Q. X., Dong X. X., Li H. D., & Ma X. Treatment with hydrogen molecules prevents RANKL-induced osteoclast differentiation associated with inhibition of ROS formation and inactivation of MAPK, AKT and NF-kappa B pathways in murine RAW264.7 cells. J. Bone Miner. Metab. 32, 494-504 (2014
    • (2014) J. Bone Miner. Metab , vol.32 , pp. 494-504
    • Li, D.Z.1    Zhang, Q.X.2    Dong, X.X.3    Li, H.D.4    Ma, X.5
  • 38
    • 84883265918 scopus 로고    scopus 로고
    • Protection of oral hydrogen water as an antioxidant on pulmonary hypertension
    • He B., et al. Protection of oral hydrogen water as an antioxidant on pulmonary hypertension. Mol. Biol. Rep. 40, 5513-5521 (2013
    • (2013) Mol. Biol. Rep , vol.40 , pp. 5513-5521
    • He, B.1
  • 39
    • 84940447681 scopus 로고    scopus 로고
    • Hydrogen ameliorates pulmonary hypertension in rats by anti-inflammatory and antioxidant effects
    • Kishimoto Y., et al. Hydrogen ameliorates pulmonary hypertension in rats by anti-inflammatory and antioxidant effects. J Thorac Cardiovasc Surg. 150, 645-654 (2015
    • (2015) J Thorac Cardiovasc Surg , vol.150 , pp. 645-654
    • Kishimoto, Y.1
  • 40
    • 70349100754 scopus 로고    scopus 로고
    • Ca2+-nfatc1 signaling is an essential axis of osteoclast differentiation
    • Negishi-Koga T., & Takayanagi H. Ca2+-NFATc1 signaling is an essential axis of osteoclast differentiation. Immunol. Rev. 231, 241-256 (2009
    • (2009) Immunol. Rev , vol.231 , pp. 241-256
    • Negishi-Koga, T.1    Takayanagi, H.2
  • 41
    • 84878623525 scopus 로고    scopus 로고
    • Nfat is required for spontaneous pulmonary hypertension in superoxide dismutase 1 knockout mice
    • Ramiro-Diaz J. M., et al. NFAT is required for spontaneous pulmonary hypertension in superoxide dismutase 1 knockout mice. Am. J. Physio.l Lung Cell. Mol. Physiol. 304, L613-625 (2013
    • (2013) Am. J. Physio.l Lung Cell. Mol. Physiol , vol.304 , pp. L613-625
    • Ramiro-Diaz, J.M.1
  • 42
    • 84924335426 scopus 로고    scopus 로고
    • A calcineurin- and nfat-dependent pathway is involved in alpha-synuclein-induced degeneration of midbrain dopaminergic neurons
    • Luo J., et al A calcineurin- And NFAT-dependent pathway is involved in alpha-synuclein-induced degeneration of midbrain dopaminergic neurons. Hum. Mol. Genet. 23, 6567-6574 (2014
    • (2014) Hum. Mol. Genet , vol.23 , pp. 6567-6574
    • Luo, J.1
  • 43
    • 17944387960 scopus 로고    scopus 로고
    • Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo
    • Watson A. D., et al. Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo. J. Biol. Chem. 272, 13597-13607 (1997
    • (1997) J. Biol. Chem , vol.272 , pp. 13597-13607
    • Watson, A.D.1
  • 44
    • 81855176005 scopus 로고    scopus 로고
    • Identification of oxidized phospholipids by electrospray ionization mass spectrometry and lcms using a qqlit instrument
    • Spickett C. M., Reis A., & Pitt A. R. Identification of oxidized phospholipids by electrospray ionization mass spectrometry and LCMS using a QQLIT instrument. Free Radic. Biol. Med. 51, 2133-2149 (2011
    • (2011) Free Radic. Biol. Med , vol.51 , pp. 2133-2149
    • Spickett, C.M.1    Reis, A.2    Pitt, A.R.3
  • 45
    • 80255126153 scopus 로고    scopus 로고
    • Mass spectrometry analysis of oxidized phosphatidylcholine and phosphatidylethanolamine
    • O'Donnell V. B. Mass spectrometry analysis of oxidized phosphatidylcholine and phosphatidylethanolamine. Biochim. Biophys. Acta. 1811, 818-826 (2011
    • (2011) Biochim. Biophys. Acta , vol.1811 , pp. 818-826
    • O'Donnell, V.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.