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Volumn 3, Issue , 2013, Pages

Oral 'hydrogen water' induces neuroprotective ghrelin secretion in mice

Author keywords

[No Author keywords available]

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; GHRELIN; NEUROPROTECTIVE AGENT; WATER;

EID: 84888250631     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep03273     Document Type: Article
Times cited : (56)

References (42)
  • 1
    • 80052226753 scopus 로고    scopus 로고
    • Recent progress toward hydrogen medicine: Potential of molecular hydrogen for preventive and therapeutic applications
    • Ohta, S. Recent Progress Toward Hydrogen Medicine: Potential of Molecular Hydrogen for Preventive and Therapeutic Applications. Curr. Pharm. Des. 17, 2241-2252 (2011).
    • (2011) Curr. Pharm. Des. , vol.17 , pp. 2241-2252
    • Ohta, S.1
  • 3
    • 84880553392 scopus 로고    scopus 로고
    • H2 gas improves functional outcome after cardiac arrest to an extent comparable to therapeutic hypothermia in a rat model
    • Hayashida, K. et al. H2 gas improves functional outcome after cardiac arrest to an extent comparable to therapeutic hypothermia in a rat model. J. Am. Heart Assoc. 1, e003459 (2012).
    • (2012) J. Am. Heart Assoc. , vol.1
    • Hayashida, K.1
  • 5
    • 79959655309 scopus 로고    scopus 로고
    • Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice
    • Kamimura, N., Nishimaki, K., Ohsawa, I. & Ohta, S. Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice. Obesity (Silver Spring). 19, 1396-1403 (2011).
    • (2011) Obesity (Silver Spring). , vol.19 , pp. 1396-1403
    • Kamimura, N.1    Nishimaki, K.2    Ohsawa, I.3    Ohta, S.4
  • 7
    • 73349123786 scopus 로고    scopus 로고
    • Oral hydrogen water prevents chronic allograft nephropathy in rats
    • Cardinal, J. S. et al.Oral hydrogen water prevents chronic allograft nephropathy in rats. Kidney Int. 77, 101-109 (2009).
    • (2009) Kidney Int. , vol.77 , pp. 101-109
    • Cardinal, J.S.1
  • 8
    • 78650813355 scopus 로고    scopus 로고
    • Inhaled hydrogen gas therapy for prevention of lung transplant-induced ischemia/reperfusion injury in rats
    • Kawamura, T. et al. Inhaled hydrogen gas therapy for prevention of lung transplant-induced ischemia/reperfusion injury in rats. Transplantation 90, 1344-51 (2010).
    • (2010) Transplantation , vol.90 , pp. 1344-1351
    • Kawamura, T.1
  • 9
    • 51849085219 scopus 로고    scopus 로고
    • Hydrogen inhalation ameliorates oxidative stress in transplantation induced intestinal graft injury
    • Buchholz, B. M. et al. Hydrogen inhalation ameliorates oxidative stress in transplantation induced intestinal graft injury. Am. J. Transplant 8, 2015-24 (2008).
    • (2008) Am. J. Transplant , vol.8 , pp. 2015-2024
    • Buchholz, B.M.1
  • 10
    • 68149136575 scopus 로고    scopus 로고
    • Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice. Cancer Chemother
    • Nakashima-Kamimura, N., Mori, T., Ohsawa, I., Asoh, S. & Ohta, S. Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice. Cancer Chemother. Pharmacol. 64, 753-61 (2009).
    • (2009) Pharmacol. , vol.64 , pp. 753-761
    • Nakashima-Kamimura, N.1    Mori, T.2    Ohsawa, I.3    Asoh, S.4    Ohta, S.5
  • 11
    • 80052705021 scopus 로고    scopus 로고
    • Investigation of protective effect of hydrogen-rich water against cisplatin-induced nephrotoxicity in rats using blood oxygenation level-dependent magnetic resonance imaging
    • Matsushita, T., Kusakabe, Y., Kitamura, A., Okada, S. & Murase, K. Investigation of protective effect of hydrogen-rich water against cisplatin-induced nephrotoxicity in rats using blood oxygenation level-dependent magnetic resonance imaging. Jpn. J. Radiol. 29, 503-12 (2011).
    • (2011) Jpn. J. Radiol. , vol.29 , pp. 503-512
    • Matsushita, T.1    Kusakabe, Y.2    Kitamura, A.3    Okada, S.4    Murase, K.5
  • 12
    • 77249124396 scopus 로고    scopus 로고
    • Radioprotective effect of hydrogen in cultured cells and mice
    • Qian, L. et al. Radioprotective effect of hydrogen in cultured cells and mice. Free Radic. Res. 44, 275-282 (2010).
    • (2010) Free Radic. Res. , vol.44 , pp. 275-282
    • Qian, L.1
  • 13
    • 78650177813 scopus 로고    scopus 로고
    • Hydrogen therapy may reduce the risks related to radiation-induced oxidative stress in space flight
    • Schoenfeld, M. P. et al. Hydrogen therapy may reduce the risks related to radiation-induced oxidative stress in space flight. Med. Hypotheses 76, 117-8 (2011).
    • (2011) Med. Hypotheses , vol.76 , pp. 117-118
    • Schoenfeld, M.P.1
  • 14
    • 70349705530 scopus 로고    scopus 로고
    • Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,23,6-tetrahydropyridine mouse model of Parkinson's disease
    • Fujita, K. et al.Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. PLoS One 4, e7247 (2009).
    • (2009) PLoS One , vol.4
    • Fujita, K.1
  • 15
    • 0037378026 scopus 로고    scopus 로고
    • Oxidative stress in Parkinson's disease
    • discussion S36-8
    • Jenner, P. Oxidative stress in Parkinson's disease. Ann. Neurol. 53 Suppl 3, S26-36; discussion S36-8 (2003).
    • (2003) Ann. Neurol. 53 , vol.3 , Issue.SUPPL.
    • Jenner, P.1
  • 16
    • 84881427177 scopus 로고    scopus 로고
    • Parkinson disease: From pathology to molecular disease mechanisms
    • Dexter, D. T. & Jenner, P. Parkinson disease: from pathology to molecular disease mechanisms. Free Radic. Biol. Med. 62, 132-144 (2013).
    • (2013) Free Radic. Biol. Med. , vol.62 , pp. 132-144
    • Dexter, D.T.1    Jenner, P.2
  • 17
    • 84879602817 scopus 로고    scopus 로고
    • Pilot study of H2 therapy in Parkinson's disease: A randomized double-blind placebo-controlled trial
    • Yoritaka, A. et al. Pilot study of H2 therapy in Parkinson's disease: A randomized double-blind placebo-controlled trial. Mov. Disord. 28, 836-9 (2013).
    • (2013) Mov. Disord. , vol.28 , pp. 836-839
    • Yoritaka, A.1
  • 18
    • 0021280826 scopus 로고
    • Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6- tetrahydropyridine in mice
    • Heikkila, R. E., Hess, A. & Duvoisin, R. C. Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice. Science 224, 1451-3 (1984). (Pubitemid 14123348)
    • (1984) Science , vol.224 , Issue.4656 , pp. 1451-1453
    • Heikkila, R.E.1    Hess, A.2    Duvoisin, R.C.3
  • 19
    • 84863674859 scopus 로고    scopus 로고
    • Drinking hydrogen water and intermittent hydrogen gas exposure, but not lactulose or continuous hydrogen gas exposure, prevent 6-hydorxydopamine-induced Parkinson's disease in rats
    • Ito, M. et al. Drinking hydrogen water and intermittent hydrogen gas exposure, but not lactulose or continuous hydrogen gas exposure, prevent 6-hydorxydopamine-induced Parkinson's disease in rats. Med. Gas Res. 2, 15 (2012).
    • (2012) Med. Gas Res. , vol.2 , pp. 15
    • Ito, M.1
  • 20
    • 15544385058 scopus 로고    scopus 로고
    • Ghrelin: Structure and function
    • Kojima, M. & Kangawa, K. Ghrelin: structure and function. Physiol. Rev. 85, 495-522 (2005).
    • (2005) Physiol. Rev. , vol.85 , pp. 495-522
    • Kojima, M.1    Kangawa, K.2
  • 21
    • 1842634405 scopus 로고    scopus 로고
    • Effects of insulin, leptin, and glucagon on ghrelin secretion from isolated perfused rat stomach
    • DOI 10.1016/j.regpep.2004.01.012, PII S016701150400031X
    • Kamegai, J. et al. Effects of insulin, leptin, and glucagon on ghrelin secretion from isolated perfused rat stomach. Regul. Pept. 119, 77-81 (2004). (Pubitemid 38482105)
    • (2004) Regulatory Peptides , vol.119 , Issue.1-2 , pp. 77-81
    • Kamegai, J.1    Tamura, H.2    Shimizu, T.3    Ishii, S.4    Sugihara, H.5    Oikawa, S.6
  • 22
    • 77957668161 scopus 로고    scopus 로고
    • Ghrelin secretion stimulated by b1-adrenergic receptors in cultured ghrelinoma cells and in fasted mice
    • U. S. A.
    • Zhao, T. et al. Ghrelin secretion stimulated by b1-adrenergic receptors in cultured ghrelinoma cells and in fasted mice. Proc. Natl. Acad. Sci. U. S. A. 107, 15868-73 (2010).
    • (2010) Proc. Natl. Acad. Sci. , vol.107 , pp. 15868-15873
    • Zhao, T.1
  • 23
    • 84864387162 scopus 로고    scopus 로고
    • Insulin and norepinephrine regulate ghrelin secretion from a rat primary stomach cell culture
    • Gagnon, J.&Anini, Y. Insulin and norepinephrine regulate ghrelin secretion from a rat primary stomach cell culture. Endocrinology 153, 3646-56 (2012).
    • (2012) Endocrinology , vol.153 , pp. 3646-3656
    • Gagnon, J.1    Anini, Y.2
  • 24
    • 84872693009 scopus 로고    scopus 로고
    • Glucagon stimulates ghrelin secretion through the activation of MAPK and EPAC and potentiates the effect of norepinephrine
    • Gagnon, J. & Anini, Y. Glucagon stimulates ghrelin secretion through the activation of MAPK and EPAC and potentiates the effect of norepinephrine. Endocrinology 154, 666-74 (2013).
    • (2013) Endocrinology , vol.154 , pp. 666-674
    • Gagnon, J.1    Anini, Y.2
  • 25
    • 79959406869 scopus 로고    scopus 로고
    • Oxytocin and dopamine stimulate ghrelin secretion by the ghrelin-producing cell line,MGN3-1 in vitro
    • Iwakura, H. et al. Oxytocin and dopamine stimulate ghrelin secretion by the ghrelin-producing cell line, MGN3-1 in vitro. Endocrinology 152, 2619-25 (2011).
    • (2011) Endocrinology , vol.152 , pp. 2619-2625
    • Iwakura, H.1
  • 26
    • 78650743194 scopus 로고    scopus 로고
    • The extra-hypothalamic actions of ghrelin on neuronal function
    • Andrews, Z. B. The extra-hypothalamic actions of ghrelin on neuronal function. Trends Neurosci. 34, 31-40 (2011).
    • (2011) Trends Neurosci. , vol.34 , pp. 31-40
    • Andrews, Z.B.1
  • 28
    • 49649122302 scopus 로고    scopus 로고
    • UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals
    • Andrews, Z. B. et al. UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals. Nature 454, 846-51 (2008).
    • (2008) Nature , vol.454 , pp. 846-851
    • Andrews, Z.B.1
  • 29
    • 70449673061 scopus 로고    scopus 로고
    • Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism
    • Andrews, Z. B. et al. Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism. J. Neurosci. 29, 14057-65 (2009).
    • (2009) J. Neurosci. , vol.29 , pp. 14057-14065
    • Andrews, Z.B.1
  • 31
    • 0021954682 scopus 로고
    • Influence of chronic lactulose ingestion on the colonic metabolism of lactulose in man (an in vivo study)
    • Florent, C. et al. Influence of chronic lactulose ingestion on the colonic metabolism of lactulose in man (an in vivo study). J. Clin. Invest. 75, 608-13 (1985). (Pubitemid 15142071)
    • (1985) Journal of Clinical Investigation , vol.75 , Issue.2 , pp. 608-613
    • Florent, C.1    Flourie, B.2    Leblond, A.3
  • 32
    • 84887980933 scopus 로고    scopus 로고
    • Consumption of water containing a high concentration of molecular hydrogen reduces oxidative stress and disease activity in patients with rheumatoid arthritis: An open-label pilot study
    • Ishibashi, T. et al. Consumption of water containing a high concentration of molecular hydrogen reduces oxidative stress and disease activity in patients with rheumatoid arthritis: an open-label pilot study. Med. Gas Res. 2, 27 (2012).
    • (2012) Med. Gas Res. , vol.2 , pp. 27
    • Ishibashi, T.1
  • 33
    • 84855406078 scopus 로고    scopus 로고
    • Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors
    • Kang, K.-M. et al. Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors. Med. Gas Res. 1, 11 (2011).
    • (2011) Med. Gas Res. , vol.1 , pp. 11
    • Kang, K.-M.1
  • 35
    • 34948893564 scopus 로고    scopus 로고
    • Selection of reference genes for gene expression studies in pig tissues using SYBR green qPCR
    • Nygard, A., Jørgensen, C. B., Cirera, S. & Fredholm, M. Selection of reference genes for gene expression studies in pig tissues using SYBR green qPCR. BMC Mol. Biol. 8, 67 (2007).
    • (2007) BMC Mol. Biol. , vol.8 , pp. 67
    • Nygard, A.1    Jørgensen, C.B.2    Cirera, S.3    Fredholm, M.4
  • 36
    • 32944464489 scopus 로고    scopus 로고
    • DNA and RNA references for qRT-PCR assays in exfoliated cervical cells
    • DOI 10.2353/jmoldx.2006.050088
    • Steinau, M., Rajeevan, M. S. & Unger, E. R. DNA and RNA references for qRTPCR assays in exfoliated cervical cells. J. Mol. Diagn. 8, 113-8 (2006). (Pubitemid 43257442)
    • (2006) Journal of Molecular Diagnostics , vol.8 , Issue.1 , pp. 113-118
    • Steinau, M.1    Rajeevan, M.S.2    Unger, E.R.3
  • 37
    • 84860855463 scopus 로고    scopus 로고
    • Sensitivity of heterozygous a1,6-fucosyltransferase knock-out mice to cigarette smoke-induced emphysema: Implication of aberrant transforming growth factor-b signaling and matrix metalloproteinase gene expression
    • Gao, C. et al. Sensitivity of heterozygous a1,6-fucosyltransferase knock-out mice to cigarette smoke-induced emphysema: implication of aberrant transforming growth factor-b signaling and matrix metalloproteinase gene expression. J. Biol. Chem. 287, 16699-16708 (2012).
    • (2012) J. Biol. Chem. , vol.287 , pp. 16699-16708
    • Gao, C.1
  • 38
    • 60849124200 scopus 로고    scopus 로고
    • Galectin-1 promotes basal and kainate-induced proliferation of neural progenitors in the dentate gyrus of adult mouse hippocampus
    • Kajitani, K. et al. Galectin-1 promotes basal and kainate-induced proliferation of neural progenitors in the dentate gyrus of adult mouse hippocampus. Cell Death Differ. 16, 417-27 (2009).
    • (2009) Cell Death Differ. , vol.16 , pp. 417-427
    • Kajitani, K.1
  • 39
    • 84888238724 scopus 로고    scopus 로고
    • Correction: MAO-B Elevation in Mouse Brain Astrocytes Results in Parkinson's Pathology
    • Mallajosyula, J. K. et al. Correction: MAO-B Elevation in Mouse Brain Astrocytes Results in Parkinson's Pathology. PLoS One 7, 16 (2012).
    • (2012) PLoS One , vol.7 , pp. 16
    • Mallajosyula, J.K.1
  • 42
    • 0026339976 scopus 로고
    • Unbiased stereological estimation of the total number of neurons in thesubdivisions of the rat hippocampus using the optical fractionator
    • West, M. J., Slomianka, L.& Gundersen, H. J. Unbiased stereological estimation of the total number of neurons in thesubdivisions of the rat hippocampus using the optical fractionator. Anat. Rec. 231, 482-97 (1991). Technology
    • (1991) Anat. Rec. , vol.231 , pp. 482-497
    • West, M.J.1    Slomianka, L.2    Gundersen, H.J.3


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