Acteoside inhibits type Ι allergy through the down-regulation of Ca/NFAT and JNK MAPK signaling pathways in basophilic cells

Journal of Natural Medicines

Volumn 67, Issue 4, 2013, Pages 790-798

  Motojima, Hideko ^a   Villareal, Myra O ^a   Iijima, Rieko ^a   Han, Junkyu ^a   Isoda, Hiroko ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Acteoside; Anti allergic activity; Cistanche tubulosa; Gene expression; MAPK JNK; Microarray

Indexed keywords

ACTEOSIDE; ANTIALLERGIC AGENT; BETA N ACETYLHEXOSAMINIDASE; CALCIUM IONOPHORE; CCL1 CHEMOKINE; CHEMOKINE; IMMUNOGLOBULIN E RECEPTOR; IMMUNOGLOBULIN FC FRAGMENT; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PHORBOL 13 ACETATE 12 MYRISTATE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR NFAT;

ALLERGIC REACTION; ARTICLE; BASOPHIL; CCL1 GENE; CCL2 GENE; CCL3 GENE; CCL4 GENE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEGRANULATION; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME RELEASE; FCER1A GENE; GENE; GENE CONTROL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE IDENTIFICATION; HUMAN; HUMAN CELL; IMMEDIATE TYPE HYPERSENSITIVITY; IMMUNE RESPONSE; INTRACELLULAR SIGNALING; MICROARRAY ANALYSIS; MOLECULAR MECHANICS; NFATC1 GENE; PROTEIN EXPRESSION; TREATMENT OUTCOME; UPREGULATION;

ANIMALS; ANTI-ALLERGIC AGENTS; BASOPHILS; CALCIMYCIN; CALCIUM IONOPHORES; CELL LINE; CISTANCHE; DOWN-REGULATION; GLUCOSIDES; HUMANS; HYPERSENSITIVITY, IMMEDIATE; INTERLEUKIN-4; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; NFATC TRANSCRIPTION FACTORS; PHENOLS; RATS; RECEPTORS, IGE; RNA, MESSENGER; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84884202988     PISSN: 13403443     EISSN: 18610293     Source Type: Journal    
DOI: 10.1007/s11418-013-0753-4     Document Type: Article

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