Role of adenosine A2A receptor in cerebral ischemia reperfusion injury: Signaling to phosphorylated extracellular signal-regulated protein kinase (pERK1/2)

Neuroscience

Volumn 314, Issue , 2016, Pages 145-159

  Mohamed, R A ^a   Agha, A M ^a   Abdel Rahman, A A ^b   Nassar, N N ^a  

^a CAIRO UNIVERSITY   (Egypt)

^b EAST CAROLINA UNIVERSITY   (United States)

Author keywords

A2A; Apoptosis; Ischemia reperfusion; Microglia; Oxidative stress; PERK1 2

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; ADENOSINE A2A RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; CASPASE 3; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOCHROME C; DIACYLGLYCEROL; GLUTAMIC ACID; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN C FOS; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; 2-(2-AMINO-3-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; 5-AMINO-7-(2-PHENYLETHYL)-2-(2-FURYL)PYRAZOLO(4,3-E)-1,2,4-TRIAZOLO(1,5-C)PYRIMIDINE; ADENOSINE A2 RECEPTOR ANTAGONIST; AUTACOID; CYCLIC AMP; FLAVONOID; PYRIMIDINE DERIVATIVE; TRIAZOLE DERIVATIVE;

ADULT; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BEHAVIOR; BRAIN INFARCTION SIZE; BRAIN INJURY; BRAIN ISCHEMIA; CAROTID ARTERY OBSTRUCTION; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DOWNSTREAM PROCESSING; EXCITOTOXICITY; GLIOMA; HIPPOCAMPUS; HISTOPATHOLOGY; IMMUNOFLUORESCENCE; LIPID PEROXIDATION; LOCOMOTION; MALE; MEMORY DISORDER; MORRIS WATER MAZE TEST; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RADIOIMMUNOPRECIPITATION; RAT; REPERFUSION INJURY; ROTAROD TEST; ANIMAL; APOPTOSIS; DRUG EFFECTS; MAZE TEST; METABOLISM; MICROGLIA; MOTOR ACTIVITY; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; WISTAR RAT;

ADENOSINE A2 RECEPTOR ANTAGONISTS; ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; BRAIN-DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP; FLAVONOIDS; HIPPOCAMPUS; INFLAMMATION MEDIATORS; MALE; MAP KINASE SIGNALING SYSTEM; MAZE LEARNING; MICROGLIA; MOTOR ACTIVITY; PHOSPHORYLATION; PYRIMIDINES; RATS; RATS, WISTAR; RECEPTOR, ADENOSINE A2A; REPERFUSION INJURY; TRIAZOLES;

EID: 84954090494     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2015.11.059     Document Type: Article

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