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Volumn 8, Issue , 2011, Pages

Selective adenosine A2A receptor agonists and antagonists protect against spinal cord injury through peripheral and central effects

Author keywords

[No Author keywords available]

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR AGONIST; ADENOSINE A2A RECEPTOR ANTAGONIST; FAS LIGAND; PEPTIDES AND PROTEINS; PROTEIN BAX; PROTEIN BCL 2; PROTEIN PAR; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 2 (4 (2 CARBOXYETHYL)PHENETHYLAMINO) 5' N ETHYLCARBOXAMIDOADENOSINE; 2-(4-(2-CARBOXYETHYL)PHENETHYLAMINO)-5'-N-ETHYLCARBOXAMIDOADENOSINE; 5 AMINO 7 (2 PHENYLETHYL) 2 (2 FURYL)PYRAZOLO(4,3 E) 1,2,4 TRIAZOLO(1,5 C)PYRIMIDINE; 5-AMINO-7-(2-PHENYLETHYL)-2-(2-FURYL)PYRAZOLO(4,3-E)-1,2,4-TRIAZOLO(1,5-C)PYRIMIDINE; ADENOSINE; ADENOSINE A2 RECEPTOR AGONIST; ADENOSINE A2 RECEPTOR ANTAGONIST; DRUG DERIVATIVE; PHENETHYLAMINE DERIVATIVE; PYRIMIDINE DERIVATIVE; TRIAZOLE DERIVATIVE;

EID: 79953849292     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-8-31     Document Type: Article
Times cited : (59)

References (67)
  • 2
    • 1842419475 scopus 로고    scopus 로고
    • Degenerative and regenerative mechanisms governing spinal cord injury
    • 10.1016/j.nbd.2003.11.015, 15056450
    • Profyris C, Cheema SS, Zang D, Azari MF, Boyle K, Petratos S. Degenerative and regenerative mechanisms governing spinal cord injury. Neurobiol Dis 2004, 15:415-436. 10.1016/j.nbd.2003.11.015, 15056450.
    • (2004) Neurobiol Dis , vol.15 , pp. 415-436
    • Profyris, C.1    Cheema, S.S.2    Zang, D.3    Azari, M.F.4    Boyle, K.5    Petratos, S.6
  • 3
    • 33646577436 scopus 로고    scopus 로고
    • Degenerative and spontaneous regenerative processes after spinal cord injury
    • Hagg T, Oudega M. Degenerative and spontaneous regenerative processes after spinal cord injury. J Neurotrauma 2006, 23:264-280.
    • (2006) J Neurotrauma , vol.23 , pp. 264-280
    • Hagg, T.1    Oudega, M.2
  • 4
    • 17844371308 scopus 로고    scopus 로고
    • Adenosine in tissue protection and tissue re generation
    • 10.1124/mol.105.011783, 15703375
    • Linden J. Adenosine in tissue protection and tissue re generation. Mol Pharmacol 2005, 67:1385-1387. 10.1124/mol.105.011783, 15703375.
    • (2005) Mol Pharmacol , vol.67 , pp. 1385-1387
    • Linden, J.1
  • 5
    • 1942425481 scopus 로고    scopus 로고
    • The pathology of human spinal cord injury: defining the problems
    • 10.1089/089771504323004575, 15115592
    • Norenberg MD, Smith J, Marcillo A. The pathology of human spinal cord injury: defining the problems. J Neurotrauma 2004, 21:429-440. 10.1089/089771504323004575, 15115592.
    • (2004) J Neurotrauma , vol.21 , pp. 429-440
    • Norenberg, M.D.1    Smith, J.2    Marcillo, A.3
  • 6
    • 39049168157 scopus 로고    scopus 로고
    • The quest to repair the damaged spinal cord
    • 10.2174/157488906775245264, 18221191
    • Moreno-Flores MT, Avila J. The quest to repair the damaged spinal cord. Recent Pat CNS Drug Discov 2006, 1:55-63. 10.2174/157488906775245264, 18221191.
    • (2006) Recent Pat CNS Drug Discov , vol.1 , pp. 55-63
    • Moreno-Flores, M.T.1    Avila, J.2
  • 7
    • 12244312473 scopus 로고    scopus 로고
    • Peroxynitrite generated in the rat spinal cord induces oxidation and nitration of proteins: reduction by Mn (III) tetrakis (4-benzoic acid) porphyrin
    • Bao F, DeWitt DS, Prough DS, Liu D. Peroxynitrite generated in the rat spinal cord induces oxidation and nitration of proteins: reduction by Mn (III) tetrakis (4-benzoic acid) porphyrin. J Neuroscience Res 2003, 71:220-227.
    • (2003) J Neuroscience Res , vol.71 , pp. 220-227
    • Bao, F.1    DeWitt, D.S.2    Prough, D.S.3    Liu, D.4
  • 10
    • 33748564678 scopus 로고    scopus 로고
    • Neutralization of the chemokine CXCL10 reduces apoptosis and increases axon sprouting after spinal cord injury
    • Glaser J, Gonzalez R, Sadr E, Keirstead HS. Neutralization of the chemokine CXCL10 reduces apoptosis and increases axon sprouting after spinal cord injury. J Neuroscience Res 2006, 84:724-734.
    • (2006) J Neuroscience Res , vol.84 , pp. 724-734
    • Glaser, J.1    Gonzalez, R.2    Sadr, E.3    Keirstead, H.S.4
  • 13
    • 33747185041 scopus 로고    scopus 로고
    • Mouse spinal cord compression injury is reduced by either activation of the adenosine A2A receptor on bone marrow-derived cells or deletion of the A2A receptor on non-bone marrow-derived cells
    • 10.1016/j.neuroscience.2006.05.014, 16777350
    • Li Y, Oskouian RJ, Day YJ, Rieger JM, Liu L, Kern JA, Linden J. Mouse spinal cord compression injury is reduced by either activation of the adenosine A2A receptor on bone marrow-derived cells or deletion of the A2A receptor on non-bone marrow-derived cells. Neuroscience 2006, 141:2029-2039. 10.1016/j.neuroscience.2006.05.014, 16777350.
    • (2006) Neuroscience , vol.141 , pp. 2029-2039
    • Li, Y.1    Oskouian, R.J.2    Day, Y.J.3    Rieger, J.M.4    Liu, L.5    Kern, J.A.6    Linden, J.7
  • 14
    • 73849141097 scopus 로고    scopus 로고
    • The selective adenosine A2A receptor agonist CGS 21680 reduces JNK MAPK activation in oligodendrocytes in injured spinal cord
    • 10.1097/SHK.0b013e3181a20792, 19295488
    • Genovese T, Melani A, Esposito E, Mazzon E, Di Paola R, Bramanti P, Pedata F, Cuzzocrea S. The selective adenosine A2A receptor agonist CGS 21680 reduces JNK MAPK activation in oligodendrocytes in injured spinal cord. Shock 2009, 32:578-585. 10.1097/SHK.0b013e3181a20792, 19295488.
    • (2009) Shock , vol.32 , pp. 578-585
    • Genovese, T.1    Melani, A.2    Esposito, E.3    Mazzon, E.4    Di Paola, R.5    Bramanti, P.6    Pedata, F.7    Cuzzocrea, S.8
  • 16
    • 27744544857 scopus 로고    scopus 로고
    • JNK activation contributes to DP5 induction and apoptosis following traumatic spinal cord injury
    • 10.1016/j.nbd.2005.05.026, 16005241
    • Yin KJ, Kim GM, Lee JM, He YY, Xu J, Hsu CY. JNK activation contributes to DP5 induction and apoptosis following traumatic spinal cord injury. Neurobiol Dis 2005, 20:881-889. 10.1016/j.nbd.2005.05.026, 16005241.
    • (2005) Neurobiol Dis , vol.20 , pp. 881-889
    • Yin, K.J.1    Kim, G.M.2    Lee, J.M.3    He, Y.Y.4    Xu, J.5    Hsu, C.Y.6
  • 17
    • 47349101224 scopus 로고    scopus 로고
    • Modulation of ischemic brain injury and neuroinflammation by adenosine A2A receptors
    • 10.2174/138161208784480126, 18537672
    • Chen JF, Pedata F. Modulation of ischemic brain injury and neuroinflammation by adenosine A2A receptors. Curr Pharm Des 2008, 14:1490-1499. 10.2174/138161208784480126, 18537672.
    • (2008) Curr Pharm Des , vol.14 , pp. 1490-1499
    • Chen, J.F.1    Pedata, F.2
  • 19
    • 0029417320 scopus 로고
    • The effects of selective A1 and A2a adenosine receptor antagonists on cerebral ischemic injury in the gerbil
    • 10.1016/0006-8993(95)01153-6, 8821736
    • Phillis JW. The effects of selective A1 and A2a adenosine receptor antagonists on cerebral ischemic injury in the gerbil. Brain Res 1995, 705:79-84. 10.1016/0006-8993(95)01153-6, 8821736.
    • (1995) Brain Res , vol.705 , pp. 79-84
    • Phillis, J.W.1
  • 20
    • 0037427516 scopus 로고    scopus 로고
    • The selective A2A receptor antagonist SCH 58261 reduces striatal transmitter outflow, turning behavior and ischemic brain damage induced by permanent focal ischemia in the rat
    • 10.1016/S0006-8993(02)03753-8, 12493612
    • Melani A, Pantoni L, Bordoni F, Gianfriddo M, Bianchi L, Vannucchi MG, Bertorelli R, Monopoli A, Pedata F. The selective A2A receptor antagonist SCH 58261 reduces striatal transmitter outflow, turning behavior and ischemic brain damage induced by permanent focal ischemia in the rat. Brain Res 2003, 959:243-250. 10.1016/S0006-8993(02)03753-8, 12493612.
    • (2003) Brain Res , vol.959 , pp. 243-250
    • Melani, A.1    Pantoni, L.2    Bordoni, F.3    Gianfriddo, M.4    Bianchi, L.5    Vannucchi, M.G.6    Bertorelli, R.7    Monopoli, A.8    Pedata, F.9
  • 21
    • 33644956171 scopus 로고    scopus 로고
    • The selective A2A receptor antagonist SCH 58261 protects from neurological deficit, brain damage and activation of p38 MAPK in rat focal cerebral ischemia
    • 10.1016/j.brainres.2005.12.010, 16443200
    • Melani A, Gianfriddo M, Vannucchi MG, Cipriani S, Baraldi PG, Giovannini MG, Pedata F. The selective A2A receptor antagonist SCH 58261 protects from neurological deficit, brain damage and activation of p38 MAPK in rat focal cerebral ischemia. Brain Res 2006, 1073-1074:470-480. 10.1016/j.brainres.2005.12.010, 16443200.
    • (2006) Brain Res , vol.1073-1074 , pp. 470-480
    • Melani, A.1    Gianfriddo, M.2    Vannucchi, M.G.3    Cipriani, S.4    Baraldi, P.G.5    Giovannini, M.G.6    Pedata, F.7
  • 22
    • 67649395906 scopus 로고    scopus 로고
    • Selective adenosine A2a receptor antagonism reduces JNK activation in oligodendrocytes after cerebral ischaemia
    • 10.1093/brain/awp076, 19359287
    • Melani A, Cipriani S, Vannucchi MG, Nosi D, Donati C, Bruni P, Giovannini MG, Pedata F. Selective adenosine A2a receptor antagonism reduces JNK activation in oligodendrocytes after cerebral ischaemia. Brain 2009, 132:1480-1495. 10.1093/brain/awp076, 19359287.
    • (2009) Brain , vol.132 , pp. 1480-1495
    • Melani, A.1    Cipriani, S.2    Vannucchi, M.G.3    Nosi, D.4    Donati, C.5    Bruni, P.6    Giovannini, M.G.7    Pedata, F.8
  • 23
    • 0033959045 scopus 로고    scopus 로고
    • Adenosine release upon spinal cord injury
    • 10.1016/S0006-8993(99)02333-1, 10784116
    • McAdoo DJ, Robak G, Xu GY, Hughes MG. Adenosine release upon spinal cord injury. Brain Res 2000, 854:152-157. 10.1016/S0006-8993(99)02333-1, 10784116.
    • (2000) Brain Res , vol.854 , pp. 152-157
    • McAdoo, D.J.1    Robak, G.2    Xu, G.Y.3    Hughes, M.G.4
  • 25
    • 0017992470 scopus 로고
    • Effect of duration of acute spinal cord compression in a new acute cord injury model in the rat
    • Rivlin AS, Tator CH. Effect of duration of acute spinal cord compression in a new acute cord injury model in the rat. Surgical neurology 1978, 10:38-43.
    • (1978) Surgical neurology , vol.10 , pp. 38-43
    • Rivlin, A.S.1    Tator, C.H.2
  • 26
    • 0033577061 scopus 로고    scopus 로고
    • Striatal A2A adenosine receptors differentially regulate spontaneous and K+-evoked glutamate release in vivo in young and aged rats
    • 10.1097/00001756-199903170-00005, 10208531
    • Corsi C, Melani A, Bianchi L, Pepeu G, Pedata F. Striatal A2A adenosine receptors differentially regulate spontaneous and K+-evoked glutamate release in vivo in young and aged rats. Neuroreport 1999, 10:687-691. 10.1097/00001756-199903170-00005, 10208531.
    • (1999) Neuroreport , vol.10 , pp. 687-691
    • Corsi, C.1    Melani, A.2    Bianchi, L.3    Pepeu, G.4    Pedata, F.5
  • 27
    • 0034601298 scopus 로고    scopus 로고
    • Striatal A2A adenosine receptor antagonism differentially modifies striatal glutamate outflow in vivo in young and aged rats
    • 10.1097/00001756-200008030-00048, 10943728
    • Corsi C, Melani A, Bianchi L, Pedata F. Striatal A2A adenosine receptor antagonism differentially modifies striatal glutamate outflow in vivo in young and aged rats. Neuroreport 2000, 11:2591-2595. 10.1097/00001756-200008030-00048, 10943728.
    • (2000) Neuroreport , vol.11 , pp. 2591-2595
    • Corsi, C.1    Melani, A.2    Bianchi, L.3    Pedata, F.4
  • 28
    • 33645983692 scopus 로고    scopus 로고
    • Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains
    • 10.1089/neu.2006.23.635, 16689667
    • Basso DM, Fisher LC, Anderson AJ, Jakeman LB, McTigue DM, Popovich PG. Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains. J Neurotrauma 2006, (23):635-59. 10.1089/neu.2006.23.635, 16689667.
    • (2006) J Neurotrauma , Issue.23 , pp. 635-659
    • Basso, D.M.1    Fisher, L.C.2    Anderson, A.J.3    Jakeman, L.B.4    McTigue, D.M.5    Popovich, P.G.6
  • 29
    • 0034194559 scopus 로고    scopus 로고
    • Developmental expression of OSP/claudin-11
    • 10.1002/(SICI)1097-4547(20000501)60:3<284::AID-JNR2>3.0.CO;2-T, 10797530
    • Bronstein JM, Chen K, Tiwari-Woodruff S, Kornblum HI. Developmental expression of OSP/claudin-11. J Neurosci Res 2000, 60:284-290. 10.1002/(SICI)1097-4547(20000501)60:3<284::AID-JNR2>3.0.CO;2-T, 10797530.
    • (2000) J Neurosci Res , vol.60 , pp. 284-290
    • Bronstein, J.M.1    Chen, K.2    Tiwari-Woodruff, S.3    Kornblum, H.I.4
  • 30
    • 0036713818 scopus 로고    scopus 로고
    • Adenosine A2A agonist reduces paralysis after spinal cord ischemia: correlation with A2A receptor expression on motor neurons
    • 10.1016/S0003-4975(02)03793-1, 12238849
    • Cassada DC, Tribble CG, Long SM, Kaza AK, Linden J, Rieger JM, Rosin D, Kron IL, Kern JA. Adenosine A2A agonist reduces paralysis after spinal cord ischemia: correlation with A2A receptor expression on motor neurons. Ann Thorac Surg 2002, 74:846-849. 10.1016/S0003-4975(02)03793-1, 12238849.
    • (2002) Ann Thorac Surg , vol.74 , pp. 846-849
    • Cassada, D.C.1    Tribble, C.G.2    Long, S.M.3    Kaza, A.K.4    Linden, J.5    Rieger, J.M.6    Rosin, D.7    Kron, I.L.8    Kern, J.A.9
  • 31
    • 69249202366 scopus 로고    scopus 로고
    • Triggering neurotrophic factor actions through adenosine A2A receptor activation: implications for neuroprotection
    • 10.1111/j.1476-5381.2009.00157.x, 2795259, 19508402
    • Sebastiao AM, Ribeiro J. Triggering neurotrophic factor actions through adenosine A2A receptor activation: implications for neuroprotection. Br J Pharmacol 2009, 158:15-22. 10.1111/j.1476-5381.2009.00157.x, 2795259, 19508402.
    • (2009) Br J Pharmacol , vol.158 , pp. 15-22
    • Sebastiao, A.M.1    Ribeiro, J.2
  • 32
    • 1842558602 scopus 로고    scopus 로고
    • Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury
    • 10.1007/s00018-003-3319-x, 15052409
    • Arundine M, Tymianski M. Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury. Cell Mol Life Sci 2004, 61:657-668. 10.1007/s00018-003-3319-x, 15052409.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 657-668
    • Arundine, M.1    Tymianski, M.2
  • 33
    • 33646571167 scopus 로고    scopus 로고
    • Pharmacological approaches to repair the injured spinal cord
    • 10.1089/neu.2006.23.318, 16629619
    • Baptiste DC, Fehlings MG. Pharmacological approaches to repair the injured spinal cord. J Neurotrauma 2006, 23:318-334. 10.1089/neu.2006.23.318, 16629619.
    • (2006) J Neurotrauma , vol.23 , pp. 318-334
    • Baptiste, D.C.1    Fehlings, M.G.2
  • 34
    • 0027933966 scopus 로고
    • Dextrorphan inhibits the release of excitatory amino acids during spinal cord ischemia
    • 10.1016/0003-4975(94)92200-4, 7915102
    • Rokkas CK, Helfrich LR, Lobner DC, Choi DW, Kouchoukos NT. Dextrorphan inhibits the release of excitatory amino acids during spinal cord ischemia. Ann Thorac Surg 1994, 58:312-319. 10.1016/0003-4975(94)92200-4, 7915102.
    • (1994) Ann Thorac Surg , vol.58 , pp. 312-319
    • Rokkas, C.K.1    Helfrich, L.R.2    Lobner, D.C.3    Choi, D.W.4    Kouchoukos, N.T.5
  • 35
    • 0029059356 scopus 로고
    • Profound systemic hypothermia inhibits the release of neurotransmitter amino acids in spinal cord ischemia
    • 10.1016/S0022-5223(05)80006-6, 7609553
    • Rokkas CK, Cronin CS, Nitta T, Helfrich LR, Lobner DC, Choi DW, Kouchoukos NT. Profound systemic hypothermia inhibits the release of neurotransmitter amino acids in spinal cord ischemia. J Thorac Cardiovasc Surg 1995, 110:27-35. 10.1016/S0022-5223(05)80006-6, 7609553.
    • (1995) J Thorac Cardiovasc Surg , vol.110 , pp. 27-35
    • Rokkas, C.K.1    Cronin, C.S.2    Nitta, T.3    Helfrich, L.R.4    Lobner, D.C.5    Choi, D.W.6    Kouchoukos, N.T.7
  • 36
    • 0031046652 scopus 로고    scopus 로고
    • Effects of moderate hypothermia on extracellular lactic acid and amino acids after severe compression injury of rat spinal cord
    • 10.1089/neu.1997.14.63, 9048312
    • Farooque M, Hillered L, Holtz A, Olsson Y. Effects of moderate hypothermia on extracellular lactic acid and amino acids after severe compression injury of rat spinal cord. J Neurotrauma 1997, 14:63-69. 10.1089/neu.1997.14.63, 9048312.
    • (1997) J Neurotrauma , vol.14 , pp. 63-69
    • Farooque, M.1    Hillered, L.2    Holtz, A.3    Olsson, Y.4
  • 37
    • 0025986461 scopus 로고
    • Review of experimental spinal cord injury with emphasis on the local and systemic circulatory effects
    • Tator CH. Review of experimental spinal cord injury with emphasis on the local and systemic circulatory effects. Neurochirurgie 1991, 37:291-302.
    • (1991) Neurochirurgie , vol.37 , pp. 291-302
    • Tator, C.H.1
  • 38
    • 0027288332 scopus 로고
    • Pathophysiology of spinal cord trauma
    • 10.1016/S0196-0644(05)82739-8, 8503537
    • Anderson DK, Hall ED. Pathophysiology of spinal cord trauma. Ann Emerg Med 1993, 22:987-992. 10.1016/S0196-0644(05)82739-8, 8503537.
    • (1993) Ann Emerg Med , vol.22 , pp. 987-992
    • Anderson, D.K.1    Hall, E.D.2
  • 39
    • 33846196606 scopus 로고    scopus 로고
    • Role of peroxynitrite in secondary oxidative damage after spinal cord injury
    • 10.1111/j.1471-4159.2006.04312.x, 17181549
    • Xiong Y, Rabchevsky AG, Hall ED. Role of peroxynitrite in secondary oxidative damage after spinal cord injury. J Neurochem 2007, 100:639-649. 10.1111/j.1471-4159.2006.04312.x, 17181549.
    • (2007) J Neurochem , vol.100 , pp. 639-649
    • Xiong, Y.1    Rabchevsky, A.G.2    Hall, E.D.3
  • 40
    • 56649112937 scopus 로고    scopus 로고
    • Adenosine modulates excitatory synaptic transmission and suppresses neuronal death induced by ischaemia in rat spinal motoneurones
    • 10.1007/s00424-008-0542-1, 18584206
    • Miyazaki N, Nakatsuka T, Takeda D, Nohda K, Inoue K, Yoshida M. Adenosine modulates excitatory synaptic transmission and suppresses neuronal death induced by ischaemia in rat spinal motoneurones. Pflugers Arch 2008, 457:441-451. 10.1007/s00424-008-0542-1, 18584206.
    • (2008) Pflugers Arch , vol.457 , pp. 441-451
    • Miyazaki, N.1    Nakatsuka, T.2    Takeda, D.3    Nohda, K.4    Inoue, K.5    Yoshida, M.6
  • 41
    • 0031969591 scopus 로고    scopus 로고
    • Protection against kainate-induced excitotoxicity by adenosine A2A receptor agonists and antagonists
    • 10.1016/S0306-4522(97)00613-1, 9607714
    • Jones PA, Smith RA, Stone TW. Protection against kainate-induced excitotoxicity by adenosine A2A receptor agonists and antagonists. Neuroscience 1998, 85:229-237. 10.1016/S0306-4522(97)00613-1, 9607714.
    • (1998) Neuroscience , vol.85 , pp. 229-237
    • Jones, P.A.1    Smith, R.A.2    Stone, T.W.3
  • 42
    • 0032479984 scopus 로고    scopus 로고
    • Protection against hippocampal kainate excitotoxicity by intracerebral administration of an adenosine A2A receptor antagonist
    • 10.1016/S0006-8993(98)00540-X, 9685693
    • Jones PA, Smith RA, Stone TW. Protection against hippocampal kainate excitotoxicity by intracerebral administration of an adenosine A2A receptor antagonist. Brain Res 1998, 800:328-335. 10.1016/S0006-8993(98)00540-X, 9685693.
    • (1998) Brain Res , vol.800 , pp. 328-335
    • Jones, P.A.1    Smith, R.A.2    Stone, T.W.3
  • 43
    • 0035876383 scopus 로고    scopus 로고
    • SCH 58261 (an adenosine A(2A) receptor antagonist) reduces, only at low doses, K(+)-evoked glutamate release in the striatum
    • 10.1016/S0014-2999(01)01058-5, 11516434
    • Pintor A, Quarta D, Pèzzola A, Reggio R, Popoli P. SCH 58261 (an adenosine A(2A) receptor antagonist) reduces, only at low doses, K(+)-evoked glutamate release in the striatum. Eur J Pharmacol 2001, 421:177-180. 10.1016/S0014-2999(01)01058-5, 11516434.
    • (2001) Eur J Pharmacol , vol.421 , pp. 177-180
    • Pintor, A.1    Quarta, D.2    Pèzzola, A.3    Reggio, R.4    Popoli, P.5
  • 44
    • 0036522987 scopus 로고    scopus 로고
    • Blockade of striatal adenosine A2A receptor reduces, through a presynaptic mechanism, quinolinic acid-induced excitotoxicity: possible relevance to neuroprotective interventions in neurodegenerative diseases of the striatum
    • Popoli P, Pintor A, Domenici MR, Frank C, Tebano MT, Pè zzola A, Scarchilli L, Quarta D, Reggio R, Malchiodi-Albedi F, Falchi M, Massotti M. Blockade of striatal adenosine A2A receptor reduces, through a presynaptic mechanism, quinolinic acid-induced excitotoxicity: possible relevance to neuroprotective interventions in neurodegenerative diseases of the striatum. J Neurosci 2002, 22:1967-1975.
    • (2002) J Neurosci , vol.22 , pp. 1967-1975
    • Popoli, P.1    Pintor, A.2    Domenici, M.R.3    Frank, C.4    Tebano, M.T.5    Pè zzola, A.6    Scarchilli, L.7    Quarta, D.8    Reggio, R.9    Malchiodi-Albedi, F.10    Falchi, M.11    Massotti, M.12
  • 45
    • 77951571892 scopus 로고    scopus 로고
    • Local glutamate level dictates adenosine A2A receptor regulation of neuroinflammation and traumatic brain injury
    • 10.1523/JNEUROSCI.0268-10.2010, 20410132
    • Dai SS, Zhou YG, Li W, An JH, Li P, Yang N, Chen XY, Xiong RP, Liu P, Zhao Y, Shen HY, Zhu PF, Chen JF. Local glutamate level dictates adenosine A2A receptor regulation of neuroinflammation and traumatic brain injury. J Neurosci 2010, 30:5802-5810. 10.1523/JNEUROSCI.0268-10.2010, 20410132.
    • (2010) J Neurosci , vol.30 , pp. 5802-5810
    • Dai, S.S.1    Zhou, Y.G.2    Li, W.3    An, J.H.4    Li, P.5    Yang, N.6    Chen, X.Y.7    Xiong, R.P.8    Liu, P.9    Zhao, Y.10    Shen, H.Y.11    Zhu, P.F.12    Chen, J.F.13
  • 46
    • 0029670309 scopus 로고    scopus 로고
    • Binding of the radioligand [3H]-SCH 58261, a new non-xanthine A2A adenosine receptor antagonist, to rat striatal membranes
    • 1909468, 8730729
    • Zocchi C, Ongini E, Ferrara S, Baraldi PG, Dionisotti S. Binding of the radioligand [3H]-SCH 58261, a new non-xanthine A2A adenosine receptor antagonist, to rat striatal membranes. Br J Pharmacol 1996, 117:1381-1386. 1909468, 8730729.
    • (1996) Br J Pharmacol , vol.117 , pp. 1381-1386
    • Zocchi, C.1    Ongini, E.2    Ferrara, S.3    Baraldi, P.G.4    Dionisotti, S.5
  • 47
    • 1842714304 scopus 로고    scopus 로고
    • Adenosine A2A receptor-induced inhibition of NMDA and GABAA receptor-mediated synaptic currents in a subpopulation of rat striatal neurons
    • 10.1016/j.neuropharm.2004.01.008, 15081796
    • Wirkner K, Gerevich Z, Krause T, Gü nther A, Kö les L, Schneider D, Nö renberg W, Illes P. Adenosine A2A receptor-induced inhibition of NMDA and GABAA receptor-mediated synaptic currents in a subpopulation of rat striatal neurons. Neuropharmacology 2004, 46:994-1007. 10.1016/j.neuropharm.2004.01.008, 15081796.
    • (2004) Neuropharmacology , vol.46 , pp. 994-1007
    • Wirkner, K.1    Gerevich, Z.2    Krause, T.3    Gü nther, A.4    Kö les, L.5    Schneider, D.6    Nö renberg, W.7    Illes, P.8
  • 48
    • 36249032646 scopus 로고    scopus 로고
    • Adenosine A2A receptors and brain injury: broad spectrum of neuroprotection, multifaceted actions and "fine tuning" modulation
    • 10.1016/j.pneurobio.2007.09.002, 18023959
    • Chen JF, Sonsalla PK, Pedata F, Melani A, Domenici MR, Popoli P, Geiger J, Lopes LV, de Mendonça A. Adenosine A2A receptors and brain injury: broad spectrum of neuroprotection, multifaceted actions and "fine tuning" modulation. Prog Neurobiol 2007, 83:310-331. 10.1016/j.pneurobio.2007.09.002, 18023959.
    • (2007) Prog Neurobiol , vol.83 , pp. 310-331
    • Chen, J.F.1    Sonsalla, P.K.2    Pedata, F.3    Melani, A.4    Domenici, M.R.5    Popoli, P.6    Geiger, J.7    Lopes, L.V.8    de Mendonça, A.9
  • 49
    • 0031594199 scopus 로고    scopus 로고
    • Cardiovascular pharmacology of the A2A adenosine receptor antagonist, SCH 58261, in the rat
    • Monopoli A, Casati C, Lozza G, Forlani A, Ongini E. Cardiovascular pharmacology of the A2A adenosine receptor antagonist, SCH 58261, in the rat. J Pharmacol Exp Ther 1998, 285:9-15.
    • (1998) J Pharmacol Exp Ther , vol.285 , pp. 9-15
    • Monopoli, A.1    Casati, C.2    Lozza, G.3    Forlani, A.4    Ongini, E.5
  • 50
    • 7044247188 scopus 로고    scopus 로고
    • Selective inactivation or reconstitution of adenosine A2A receptors in bone marrow cells reveals their significant contribution to the development of ischemic brain injury
    • 10.1038/nm1103, 15448683
    • Yu L, Huang Z, Mariani J, Wang Y, Moskowitz M, Chen JF. Selective inactivation or reconstitution of adenosine A2A receptors in bone marrow cells reveals their significant contribution to the development of ischemic brain injury. Nat Med 2004, 10:1081-1087. 10.1038/nm1103, 15448683.
    • (2004) Nat Med , vol.10 , pp. 1081-1087
    • Yu, L.1    Huang, Z.2    Mariani, J.3    Wang, Y.4    Moskowitz, M.5    Chen, J.F.6
  • 51
    • 0037441343 scopus 로고    scopus 로고
    • Use of the A(2A) adenosine receptor as a physiological immunosuppressor and to engineer inflammation in vivo
    • 10.1016/S0006-2952(02)01548-4, 12566076
    • Sitkovsky MV. Use of the A(2A) adenosine receptor as a physiological immunosuppressor and to engineer inflammation in vivo. Biochem Pharmacol 2003, 65:493-501. 10.1016/S0006-2952(02)01548-4, 12566076.
    • (2003) Biochem Pharmacol , vol.65 , pp. 493-501
    • Sitkovsky, M.V.1
  • 52
    • 33751543485 scopus 로고    scopus 로고
    • Adenosine A2A receptor activation reduces hepatic ischemia reperfusion injury by inhibiting CD1d-dependent NKT cell activation
    • 10.1084/jem.20061097, 2118143, 17088433
    • Lappas CM, Day YJ, Marshall MA, Engelhard VH, Linden J. Adenosine A2A receptor activation reduces hepatic ischemia reperfusion injury by inhibiting CD1d-dependent NKT cell activation. J Exp Med 2006, 203:2639-2648. 10.1084/jem.20061097, 2118143, 17088433.
    • (2006) J Exp Med , vol.203 , pp. 2639-2648
    • Lappas, C.M.1    Day, Y.J.2    Marshall, M.A.3    Engelhard, V.H.4    Linden, J.5
  • 53
    • 33747785278 scopus 로고    scopus 로고
    • Cutting edge: Critical role for A2A adenosine receptors in the T cell-mediated regulation of colitis
    • Naganuma M, Wiznerowicz EB, Lappas CM, Linden J, Worthington MT, Ernst PB. Cutting edge: Critical role for A2A adenosine receptors in the T cell-mediated regulation of colitis. J Immunol 2006, 177:2765-2769.
    • (2006) J Immunol , vol.177 , pp. 2765-2769
    • Naganuma, M.1    Wiznerowicz, E.B.2    Lappas, C.M.3    Linden, J.4    Worthington, M.T.5    Ernst, P.B.6
  • 54
    • 0033043321 scopus 로고    scopus 로고
    • Expression of A2B adenosine receptors in human lymphocytes: their role in T cell activation
    • Mirabet M, Herrera C, Cordero OJ, Mallol J, Lluis C, Franco R. Expression of A2B adenosine receptors in human lymphocytes: their role in T cell activation. J Cell Sci 1999, 112:491-502.
    • (1999) J Cell Sci , vol.112 , pp. 491-502
    • Mirabet, M.1    Herrera, C.2    Cordero, O.J.3    Mallol, J.4    Lluis, C.5    Franco, R.6
  • 55
    • 0033970029 scopus 로고    scopus 로고
    • A(2A) adenosine receptors in human peripheral blood cells
    • 10.1038/sj.bjp.0703045, 1621134, 10694196
    • Gessi S, Varani K, Merighi S, Ongini E, Borea PA. A(2A) adenosine receptors in human peripheral blood cells. Br J Pharmacol 2000, 129:2-11. 10.1038/sj.bjp.0703045, 1621134, 10694196.
    • (2000) Br J Pharmacol , vol.129 , pp. 2-11
    • Gessi, S.1    Varani, K.2    Merighi, S.3    Ongini, E.4    Borea, P.A.5
  • 56
    • 0031691973 scopus 로고    scopus 로고
    • Suppression of macrophage inflammatory protein (MIP)-1alpha production and collagen-induced arthritis by adenosine receptor agonists
    • 10.1038/sj.bjp.0702040, 1565610, 9786512
    • Szabo C, Scott GS, Virag L, Egnaczyk G, Salzman AL, Shanley TP, Hasko G. Suppression of macrophage inflammatory protein (MIP)-1alpha production and collagen-induced arthritis by adenosine receptor agonists. Br J Pharmacol 1998, 125:379-387. 10.1038/sj.bjp.0702040, 1565610, 9786512.
    • (1998) Br J Pharmacol , vol.125 , pp. 379-387
    • Szabo, C.1    Scott, G.S.2    Virag, L.3    Egnaczyk, G.4    Salzman, A.L.5    Shanley, T.P.6    Hasko, G.7
  • 58
    • 41649119553 scopus 로고    scopus 로고
    • Critical role of hypoxia and A2A adenosine receptors in liver tissue-protecting physiological anti-inflammatory pathway
    • 2156187, 18163162
    • Choukè r A, Thiel M, Lukashev D, Ward JM, Kaufmann I, Apasov S, Sitkovsky MV, Ohta A. Critical role of hypoxia and A2A adenosine receptors in liver tissue-protecting physiological anti-inflammatory pathway. Mol Med 2008, 14:116-123. 2156187, 18163162.
    • (2008) Mol Med , vol.14 , pp. 116-123
    • Choukè r, A.1    Thiel, M.2    Lukashev, D.3    Ward, J.M.4    Kaufmann, I.5    Apasov, S.6    Sitkovsky, M.V.7    Ohta, A.8
  • 59
    • 1642578925 scopus 로고    scopus 로고
    • Antiapoptotic signaling by a remyelination-promoting human antimyelin antibody
    • 10.1016/j.nbd.2003.09.002, 14751777
    • Howe CL, Bieber AJ, Warrington AE, Pease LR, Rodriguez M. Antiapoptotic signaling by a remyelination-promoting human antimyelin antibody. Neurobiol Dis 2004, 15:120-131. 10.1016/j.nbd.2003.09.002, 14751777.
    • (2004) Neurobiol Dis , vol.15 , pp. 120-131
    • Howe, C.L.1    Bieber, A.J.2    Warrington, A.E.3    Pease, L.R.4    Rodriguez, M.5
  • 60
    • 33644799988 scopus 로고    scopus 로고
    • TRAIL-induced death of human adult oligodendrocytes is mediated by JNK pathway
    • 10.1002/glia.20249, 16206163
    • Jurewicz A, Matysiak M, Andrzejak S, Selmaj K. TRAIL-induced death of human adult oligodendrocytes is mediated by JNK pathway. Glia 2006, 53:158-166. 10.1002/glia.20249, 16206163.
    • (2006) Glia , vol.53 , pp. 158-166
    • Jurewicz, A.1    Matysiak, M.2    Andrzejak, S.3    Selmaj, K.4
  • 61
    • 0032589563 scopus 로고    scopus 로고
    • Activation of NF-kappaB and c-jun transcription factors in multiple sclerosis lesions. Implications for oligodendrocyte pathology
    • 10.1016/S0002-9440(10)65456-9, 1866971, 10550297
    • Bonetti B, Stegagno C, Cannella B, Rizzuto N, Moretto G, Raine CS. Activation of NF-kappaB and c-jun transcription factors in multiple sclerosis lesions. Implications for oligodendrocyte pathology. Am J Pathol 1999, 155:1433-1438. 10.1016/S0002-9440(10)65456-9, 1866971, 10550297.
    • (1999) Am J Pathol , vol.155 , pp. 1433-1438
    • Bonetti, B.1    Stegagno, C.2    Cannella, B.3    Rizzuto, N.4    Moretto, G.5    Raine, C.S.6
  • 62
    • 0030788643 scopus 로고    scopus 로고
    • Glutamate receptor-mediated toxicity in optic nerve oligodendrocytes
    • 10.1073/pnas.94.16.8830, 23152, 9238063
    • Matute C, Sá nchez-Gó mez MV, Martí nez-Millá n L, Miledi R. Glutamate receptor-mediated toxicity in optic nerve oligodendrocytes. Proc Natl Acad Sci USA 1997, 94:8830-8835. 10.1073/pnas.94.16.8830, 23152, 9238063.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8830-8835
    • Matute, C.1    Sá nchez-Gó mez, M.V.2    Martí nez-Millá n, L.3    Miledi, R.4
  • 64
    • 0031952612 scopus 로고    scopus 로고
    • Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity
    • 10.1038/nm0398-291, 9500601
    • McDonald JW, Althomsons SP, Hyrc KL, Choi DW, Goldberg MP. Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity. Nat Med 1998, 4:291-297. 10.1038/nm0398-291, 9500601.
    • (1998) Nat Med , vol.4 , pp. 291-297
    • McDonald, J.W.1    Althomsons, S.P.2    Hyrc, K.L.3    Choi, D.W.4    Goldberg, M.P.5
  • 65
    • 33745700290 scopus 로고    scopus 로고
    • Perinatal white matter injury: the changing spectrum of pathology and emerging insights into pathogenetic mechanisms
    • 10.1002/mrdd.20107, 16807910
    • Back SA. Perinatal white matter injury: the changing spectrum of pathology and emerging insights into pathogenetic mechanisms. Ment Retard Dev Disabil Res Rev 2006, 12:129-140. 10.1002/mrdd.20107, 16807910.
    • (2006) Ment Retard Dev Disabil Res Rev , vol.12 , pp. 129-140
    • Back, S.A.1
  • 66
    • 4444382950 scopus 로고    scopus 로고
    • Excitatory amino acid induced oligodendrocyte cell death in vitro: receptor-dependent and -independent mechanisms
    • 10.1111/j.1471-4159.2004.02584.x, 15312172
    • Rosin C, Bates TE, Skaper SD. Excitatory amino acid induced oligodendrocyte cell death in vitro: receptor-dependent and -independent mechanisms. J Neurochem 2004, 90:1173-1185. 10.1111/j.1471-4159.2004.02584.x, 15312172.
    • (2004) J Neurochem , vol.90 , pp. 1173-1185
    • Rosin, C.1    Bates, T.E.2    Skaper, S.D.3
  • 67
    • 0033820684 scopus 로고    scopus 로고
    • Adenosine inhibits IL-12 and TNF-[alpha] production via adenosine A2a receptor-dependent and independent mechanisms
    • 10.1096/fj.99-0508com, 11023991
    • Hasko G, Kuhel DG, Chen JF, Schwarzschild MA, Deitch EA, Mabley JG, Marton A, Szabo C. Adenosine inhibits IL-12 and TNF-[alpha] production via adenosine A2a receptor-dependent and independent mechanisms. Faseb J 2000, 14:2065-2074. 10.1096/fj.99-0508com, 11023991.
    • (2000) Faseb J , vol.14 , pp. 2065-2074
    • Hasko, G.1    Kuhel, D.G.2    Chen, J.F.3    Schwarzschild, M.A.4    Deitch, E.A.5    Mabley, J.G.6    Marton, A.7    Szabo, C.8


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