Transcriptional and functional complexity of Shank3 provides a molecular framework to understand the phenotypic heterogeneity of SHANK3 causing autism and Shank3 mutant mice

Molecular Autism

Volumn 5, Issue 1, 2014, Pages

  Wang, Xiaoming ^a   Xu, Qiong ^a,b   Bey, Alexandra L ^a   Lee, Yoonji ^a   Jiang, Yong Hui ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL OF FUDAN UNIVERSITY   (China)

Author keywords

Activity dependent gene regulation; Alternative splicing; Autism spectrum disorder; Phenotypic heterogeneity; Shank3 isoform

Indexed keywords

COMPLEMENTARY DNA; ISOPROTEIN; MESSENGER RNA; SHANK 3 PROTEIN; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTISM; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DENDRITIC SPINE; EPIGENETICS; EXON; GENETIC HETEROGENEITY; GENETIC TRANSCRIPTION; HIPPOCAMPAL NEURONAL CULTURE; MOUSE; MUTANT; NEUROMODULATION; NEWBORN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

MUS;

EID: 84900800634     PISSN: None     EISSN: 20402392     Source Type: Journal    
DOI: 10.1186/2040-2392-5-30     Document Type: Article

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