Using global transcription machinery engineering (gTME) to improve ethanol tolerance of Zymomonas mobilis

Microbial Cell Factories

Volumn 15, Issue 1, 2016, Pages

  Tan, Furong ^a   Wu, Bo ^a   Dai, Lichun ^a   Qin, Han ^a   Shui, Zongxia ^a   Wang, Jingli ^a   Zhu, Qili ^a   Hu, Guoquan ^a   He, Mingxiong ^a  

^a AGRO ENVIRONMENTAL PROTECTION INSTITUTE   (China)

Author keywords

Error prone PCR; Ethanol tolerance; Global transcription machinery engineering (gTME); Random mutagenesis; Zymomonas mobilis; 70

Indexed keywords

ALCOHOL; SIGMA FACTOR; BACTERIAL PROTEIN;

ADHB GENE; ALCOHOL PRODUCTION; ALCOHOL TOLERANCE; AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL GENE; BACTERIUM MUTANT; CELL DENSITY; CELL GROWTH; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; FERMENTATION TECHNIQUE; GENE EXPRESSION REGULATION; GENE SEQUENCE; GENETIC ENGINEERING; GENETIC TRANSCRIPTION; GLOBAL TRANSCRIPTION MACHINERY ENGINEERING; GLUCOSE INTAKE; GLUCOSE UTILIZATION; MUTAGENESIS; NONHUMAN; PDC GENE; PHENOTYPE; POINT MUTATION; POLYMERASE CHAIN REACTION; PROMOTER REGION; RPOD GENE; TRANSCRIPTION INITIATION; UPREGULATION; ZYMOMONAS MOBILIS; DRUG EFFECTS; FERMENTATION; GENETICS; METABOLISM; MUTATION; ZYMOMONAS;

BACTERIAL PROTEINS; ETHANOL; FERMENTATION; MUTATION; ZYMOMONAS;

EID: 84953791504     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/s12934-015-0398-y     Document Type: Article

References (37)

1. Luque R, Herrero-Davila L, Campelo JM, Clark JH, Hidalgo JM, Luna D, et al. Biofuels: a technological perspective. Energ Environ Sci. 2008;1(5):542-64.
2. Rubin EM. Genomics of cellulosic biofuels. Nature. 2008;454(7206):841-5.
3. dos Santos Dda S, Camelo AC, Rodrigues KC, Carlos LC, Pereira N Jr. Ethanol production from sugarcane bagasse by Zymomonas mobilis using simultaneous saccharification and fermentation (SSF) process. Appl Biochem Biotechnol. 2010;161(1-8):93-105.
4. He MX, Wu B, Qin H, Ruan ZY, Tan FR, Wang JL, et al. Zymomonas mobilis: a novel platform for future biorefineries. Biotechnol Biofuels. 2014;7(1):101-15.
5. Jeon YJ, Xun Z, Rogers PL. Comparative evaluations of cellulosic raw materials for second generation bioethanol production. Lett Appl Microbiol. 2010;51(5):518-24.
6. Rogers PL, Jeon YJ, Lee KJ, Lawford HG. Zymomonas mobilis for fuel ethanol and higher value products. Adv Biochem Eng Biotechnol. 2007;108:263-88.
7. Franden MA, Pilath HM, Mohagheghi A, Pienkos PT, Zhang M. Inhibition of growth of Zymomonas mobilis by model compounds found in lignocellulosic. Biotechnol Biofuels. 2013;6:99-113.
8. Michel GP, Starka J. Effect of ethanol and heat on the protein pattern of Zymomonas mobilis. J Bacteriol. 1986;165(3):1040-2.
9. Thanonkeo P, Laopaiboon P, Sootsuwan K, Yamada M. Magnesium ions improve growth and ethanol production of Zymomonas mobilis under heat or ethanol stress. Biotechnology. 2007;6(1):112-9.
10. Chen M. irrE, an exogenous gene from Deinococcus radiodurans, improves the growth of and ethanol production by a Zymomonas mobilis strain under ethanol and acid stresses. J Microbiol Biotechnol. 2010;20(7):1156-62.
11. Luo LH, Seo PS, Seo JW, Heo SY, Kim DH, Kim CH. Improved ethanol tolerance in Escherichia coli by changing the cellular fatty acids composition through genetic manipulation. Biotechnol Lett. 2009;31(12):1867-71.
12. Shi DJ, Wang CL, Wang KM. Genome shuffling to improve thermotolerance, ethanol tolerance and ethanol productivity of Saccharomyces cerevisiae. J Ind Microbiol Biotechnol. 2009;36(1):139-47.
13. Tao F, Miao JY, Shi GY, Zhang KC. Ethanol fermentation by an acid-tolerant Zymomonas mobilis under non-sterilized condition. Process Biochem. 2005;40(1):183-7.
14. Yang S, Land ML, Klingeman DM, Pelletier DA, Lu TY, Martin SL, et al. Paradigm for industrial strain improvement identifies sodium acetate tolerance loci in Zymomonas mobilis and Saccharomyces cerevisiae. Proc Natl Acad Sci USA. 2010;107(23):10395-400.
15. He MX, Wu B, Shui ZX, Hu QC, Wang WG, Tan FR, et al. Transcriptome profiling of Zymomonas mobilis under furfural stress. Appl Microbiol Biotechnol. 2012;95(1):189-99.
16. He MX, Wu B, Shui ZX, Hu QC, Wang WG, Tan FR, et al. Transcriptome profiling of Zymomonas mobilis under ethonal stress. Biotechnol Biofuels. 2012;5:75-84.
17. Yang S, Pan C, Tschaplinski TJ, Hurst GB, Engle NL, Zhou W, et al. Systems biology analysis of Zymomonas mobilis ZM4 ethanol stress responses. PLoS One. 2013;8(7):68886-99.
18. Kasavi C, Eraslan S, Arga KY, Oner ET, Kirdar B. A system based network approach to ethanol tolerance in Saccharomyces cerevisiae. BMC Syst Biol. 2014;8(1):90-103.
19. Lewis JA, Broman AT, Will J, Gasch AP. Genetic Architecture of ethanol-responsive transcriptome variation in Saccharomyces cerevisiae strains. Genetics. 2014;198(1):369-82.
20. Henderson CM, Block DE. Examining the role of membrane lipid composition in determining the ethanol tolerance of Saccharomyces cerevisiae. Appl Environ Microbiol. 2014;80(10):2966-72.
21. Lee JY, Sung BH, Yu BJ, Lee JH, Lee SH, Kim MS, et al. Phenotypic engineering by reprogramming gene transcription using novel artificial transcription factors in Escherichia coli. Nucleic Acids Res. 2008;36(16):102-11.
22. Park KS, Lee DK, Lee H, Lee Y, Jang YS, Kim YH, et al. Phenotypic alteration of eukaryotic cells using randomized libraries of artificial transcription factors. Nat Biotechnol. 2003;21(10):1208-14.
23. van Tol N, van der Zaal BJ. Artificial transcription factor-mediated regulation of gene expression. Plant Sci. 2014;225:58-67.
24. Alper H, Stephanopoulos G. Global transcription machinery engineering: a new approach for improving cellular phenotype. Metab Eng. 2007;9(3):258-67.
25. Klein-Marcuschamer D, Stephanopoulos G. Assessing the potential of mutational strategies to elicit new phenotypes in industrial strains. Proc Natl Acad Sci USA. 2008;105(7):2319-24.
26. Alper H, Moxley J, Nevoigt E, Fink GR, Stephanopoulos G. Engineering yeast transcription machinery for improved ethanol tolerance and production. Science. 2006;314(5805):1565-8.
27. Hong SH, Wang X, Wood TK. Controlling biofilm formation, prophage excision and cell death by rewiring global regulator H-NS of Escherichia coli. Microb Biotechnol. 2010;3(3):344-56.
28. Hong SH, Lee J, Wood TK. Engineering global regulator Hha of Escherichia coli to control biofilm dispersal. Microb Biotechnol. 2010;3(6):717-28.
29. Chong HQ, Huang L, Yeow JW, Wang I, Zhang HF, Song H, et al. Improving ethanol tolerance of Escherichia coli by rewiring its global regulator cAMP receptor protein (CRP). PLoS One. 2013;8(2):1-9.
30. Zhang H, Chong H, Ching CB, Song H, Jiang R. Engineering global transcription factor cyclic AMP receptor protein of Escherichia coli for improved 1-butanol tolerance. Appl Microbiol Biotechnol. 2012;94(4):1107-17.
31. Kovach ME, Elzer PH, Steven Hill D, Robertson GT, Farris MA, Roop RM II, et al. Four new derivatives of the broad-host-range cloning vector pBBR1MCS, carrying different antibiotic-resistance cassettes. Gene. 1995;166:175-6.
32. Conway T, Osman YA, Konnan JI, Hoffmann EM, Ingram LO. Promoter and nucleotide sequences of the Zymomonas mobilis pyruvate decarboxylase. J Bacteriol. 1987;169(3):949-54.
33. Neale AD, Scopes RK, Kelly JM, Wettenhall REH. The two alcohol dehydrogenases of Zymomonas mobilis purification by differential dye ligand chromatography, molecular characterisation and physiological roles. Eur J Biochem. 1986;154:119-24.
34. Mackenzie KF, Eddy CK, Ingram LO. Modulation of alcohol dehydrogenase isoenzyme levels in Zymomonas mobilis by iron and zinc. J Bacteriol. 1989;171(2):1063-8.
35. NCBI conserved domain. Search for conserved domains within a protein or coding nucleotide sequence. 2015. http://www.ncbi.nlm.nih.gov/Structure/cdd/wrpsb.cgi?SEQUENCE=56544093&FULL.
36. Seo JS, Chong H, Park HS, Yoon KO, Jung C, Kim JJ, et al. The genome sequence of the ethanologenic bacterium Zymomonas mobilis ZM4. Nat Biotechnol. 2005;23(1):63-8.
37. E has an important role in stress tolerance of Yersinia pseudotuberculosis IP32953. Appl Environ Microbiol. 2013;79(19):5970-7.