메뉴 건너뛰기




Volumn 100, Issue 6, 2007, Pages 1565-1578

Fibroblast growth factor receptor 3 kinase domain mutation increases cortical progenitor proliferation via mitogen-activated protein kinase activation

Author keywords

Cell proliferation; Cerebral cortex; Development; Fibroblast growth factor receptor 3; Mitogen activated protein kinase; Neuroepithelium

Indexed keywords

BROXURIDINE; FIBROBLAST GROWTH FACTOR RECEPTOR 3; MITOGEN ACTIVATED PROTEIN KINASE; MUTANT PROTEIN; SPROUTY PROTEIN;

EID: 33847740369     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04285.x     Document Type: Article
Times cited : (30)

References (64)
  • 1
    • 0033516620 scopus 로고    scopus 로고
    • Severe achondroplasia with developmental delay and acanthosis nigricans (SADDAN): Phenotypic analysis of a new skeletal dysplasia caused by a Lys650Met mutation in fibroblast growth factor receptor 3
    • Bellus G. A., Bamshad M. J., Przylepa K. A. et al. (1999) Severe achondroplasia with developmental delay and acanthosis nigricans (SADDAN): phenotypic analysis of a new skeletal dysplasia caused by a Lys650Met mutation in fibroblast growth factor receptor 3. Am. J. Med. Genet. 85, 53-65.
    • (1999) Am. J. Med. Genet , vol.85 , pp. 53-65
    • Bellus, G.A.1    Bamshad, M.J.2    Przylepa, K.A.3
  • 2
    • 2142759556 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase signalling pathways in tumor progression, invasion and angiogenesis
    • Brader S. and Eccles S. A. (2004) Phosphoinositide 3-kinase signalling pathways in tumor progression, invasion and angiogenesis. Tumori 90, 2-8.
    • (2004) Tumori , vol.90 , pp. 2-8
    • Brader, S.1    Eccles, S.A.2
  • 3
    • 0029095348 scopus 로고
    • Numbers, time and neocortical neuronogenesis: A general developmental and evolutionary model
    • Caviness V. S. Jr, Takahashi T. and Nowakowski R. S. (1995) Numbers, time and neocortical neuronogenesis: a general developmental and evolutionary model. Trends Neurosci. 18, 379-383.
    • (1995) Trends Neurosci , vol.18 , pp. 379-383
    • Caviness Jr, V.S.1    Takahashi, T.2    Nowakowski, R.S.3
  • 4
    • 0029928791 scopus 로고    scopus 로고
    • Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3
    • Colvin J. S., Bohne B. A., Harding G.W., McEwen D. G. and Ornitz D. M. (1996) Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3. Nat. Genet. 12, 390-397.
    • (1996) Nat. Genet , vol.12 , pp. 390-397
    • Colvin, J.S.1    Bohne, B.A.2    Harding, G.W.3    McEwen, D.G.4    Ornitz, D.M.5
  • 5
    • 0142074405 scopus 로고    scopus 로고
    • Spatial and temporal patterns of ERK signaling during mouse embryogenesis
    • Corson L. B., Yamanaka Y., Lai K. M. and Rossant J. (2003) Spatial and temporal patterns of ERK signaling during mouse embryogenesis. Development 130, 4527-4537.
    • (2003) Development , vol.130 , pp. 4527-4537
    • Corson, L.B.1    Yamanaka, Y.2    Lai, K.M.3    Rossant, J.4
  • 6
    • 0028959288 scopus 로고
    • The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo
    • Crossley P. H. and Martin G. R. (1995) The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development 121, 439-451.
    • (1995) Development , vol.121 , pp. 439-451
    • Crossley, P.H.1    Martin, G.R.2
  • 7
    • 0035842571 scopus 로고    scopus 로고
    • Coordinate expression of Fgf8, Otx2, Bmp4, and Shh in the rostral prosencephalon during development of the telencephalic and optic vesicles
    • Crossley P. H., Martinez S., Ohkubo Y. and Rubenstein J. L. (2001) Coordinate expression of Fgf8, Otx2, Bmp4, and Shh in the rostral prosencephalon during development of the telencephalic and optic vesicles. Neuroscience 108, 183-206.
    • (2001) Neuroscience , vol.108 , pp. 183-206
    • Crossley, P.H.1    Martinez, S.2    Ohkubo, Y.3    Rubenstein, J.L.4
  • 9
    • 0029917507 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 3 is a negative regulator of bone growth
    • Deng C., Wynshaw-Boris A., Zhou F., Kuo A. and Leder P. (1996) Fibroblast growth factor receptor 3 is a negative regulator of bone growth. Cell 84, 911-921.
    • (1996) Cell , vol.84 , pp. 911-921
    • Deng, C.1    Wynshaw-Boris, A.2    Zhou, F.3    Kuo, A.4    Leder, P.5
  • 10
    • 0032479976 scopus 로고    scopus 로고
    • Impaired cerebral cortex development and blood pressure regulation in FGF-2-deficient mice
    • Dono R., Texido G., Dussel R., Ehmke H. and Zeller R. (1998) Impaired cerebral cortex development and blood pressure regulation in FGF-2-deficient mice. EMBO J. 17, 4213-4225.
    • (1998) EMBO J , vol.17 , pp. 4213-4225
    • Dono, R.1    Texido, G.2    Dussel, R.3    Ehmke, H.4    Zeller, R.5
  • 11
    • 0142138668 scopus 로고    scopus 로고
    • Neuroepithelial secondary organizers and cell fate specification in the developing brain
    • Echevarria D., Vieira C., Gimeno L. and Martinez S. (2003) Neuroepithelial secondary organizers and cell fate specification in the developing brain. Brain Res. Brain Res. Rev. 43, 179-191.
    • (2003) Brain Res. Brain Res. Rev , vol.43 , pp. 179-191
    • Echevarria, D.1    Vieira, C.2    Gimeno, L.3    Martinez, S.4
  • 13
    • 0041856153 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its function
    • Fong C. W., Leong H. F., Wong E. S., Lim J., Yusoff P. and Guy G. R. (2003) Tyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its function. J. Biol. Chem. 278, 33 456-33 464.
    • (2003) J. Biol. Chem , vol.278
    • Fong, C.W.1    Leong, H.F.2    Wong, E.S.3    Lim, J.4    Yusoff, P.5    Guy, G.R.6
  • 14
    • 0034949542 scopus 로고    scopus 로고
    • Fibroblast growth factors in the developing central nervous system
    • Ford-Perriss M., Abud H. and Murphy M. (2001) Fibroblast growth factors in the developing central nervous system. Clin. Exp. Pharmacol. Physiol. 28, 493-503.
    • (2001) Clin. Exp. Pharmacol. Physiol , vol.28 , pp. 493-503
    • Ford-Perriss, M.1    Abud, H.2    Murphy, M.3
  • 15
    • 0036456395 scopus 로고    scopus 로고
    • Interkinetic nuclear movement in the vertebrate neuroepithelium: Encounters with an old acquaintance
    • Frade J. M. (2002) Interkinetic nuclear movement in the vertebrate neuroepithelium: encounters with an old acquaintance. Prog. Brain Res. 136, 67-71.
    • (2002) Prog. Brain Res , vol.136 , pp. 67-71
    • Frade, J.M.1
  • 16
    • 0035798089 scopus 로고    scopus 로고
    • Neocortex patterning by the secreted signaling molecule FGF8
    • Fukuchi-Shimogori T. and Grove E. A. (2001) Neocortex patterning by the secreted signaling molecule FGF8. Science 294, 1071-1074.
    • (2001) Science , vol.294 , pp. 1071-1074
    • Fukuchi-Shimogori, T.1    Grove, E.A.2
  • 17
    • 0041708066 scopus 로고    scopus 로고
    • Emx2 patterns the neocortex by regulating FGF positional signaling
    • Fukuchi-Shimogori T. and Grove E. A. (2003) Emx2 patterns the neocortex by regulating FGF positional signaling. Nat. Neurosci. 6, 825-831.
    • (2003) Nat. Neurosci , vol.6 , pp. 825-831
    • Fukuchi-Shimogori, T.1    Grove, E.A.2
  • 18
    • 0038635952 scopus 로고    scopus 로고
    • Molecular regionalization of the neocortex is disrupted in Fgf8 hypomorphic mutants
    • Garel S., Huffman K. J. and Rubenstein J. L. (2003) Molecular regionalization of the neocortex is disrupted in Fgf8 hypomorphic mutants. Development 130, 1903-1914.
    • (2003) Development , vol.130 , pp. 1903-1914
    • Garel, S.1    Huffman, K.J.2    Rubenstein, J.L.3
  • 19
    • 0025318679 scopus 로고
    • Distribution of basic fibroblast growth factor in the 18-day rat fetus: Localization in the basement membranes of diverse tissues
    • Gonzalez A. M., Buscaglia M., Ong M. and Baird A. (1990) Distribution of basic fibroblast growth factor in the 18-day rat fetus: localization in the basement membranes of diverse tissues. J. Cell Biol. 110, 753-765.
    • (1990) J. Cell Biol , vol.110 , pp. 753-765
    • Gonzalez, A.M.1    Buscaglia, M.2    Ong, M.3    Baird, A.4
  • 20
  • 22
    • 0037452567 scopus 로고    scopus 로고
    • hSpry2 is targeted to the ubiquitin-dependent proteasome pathway by c-Cbl
    • Hall A. B., Jura N., DaSilva J., Jang Y. J., Gong D. and Bar-Sagi D. (2003) hSpry2 is targeted to the ubiquitin-dependent proteasome pathway by c-Cbl. Curr. Biol. 13, 308-314.
    • (2003) Curr. Biol , vol.13 , pp. 308-314
    • Hall, A.B.1    Jura, N.2    DaSilva, J.3    Jang, Y.J.4    Gong, D.5    Bar-Sagi, D.6
  • 23
    • 0036847930 scopus 로고    scopus 로고
    • Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway
    • Hanafusa H., Torii S., Yasunaga T. and Nishida E. (2002) Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway. Nat. Cell Biol. 4, 850-858.
    • (2002) Nat. Cell Biol , vol.4 , pp. 850-858
    • Hanafusa, H.1    Torii, S.2    Yasunaga, T.3    Nishida, E.4
  • 24
    • 0037351187 scopus 로고    scopus 로고
    • FGF signaling through FGFR1 is required for olfactory bulb morphogenesis
    • Hebert J. M., Lin M., Partanen J., Rossant J. and McConnell S. K. (2003) FGF signaling through FGFR1 is required for olfactory bulb morphogenesis. Development 130, 1101-1111.
    • (2003) Development , vol.130 , pp. 1101-1111
    • Hebert, J.M.1    Lin, M.2    Partanen, J.3    Rossant, J.4    McConnell, S.K.5
  • 25
    • 26444491115 scopus 로고    scopus 로고
    • The cerebral cortex malformation in thanatophoric dysplasia: Neuropathology and pathogenesis
    • Hevner R. F. (2005) The cerebral cortex malformation in thanatophoric dysplasia: neuropathology and pathogenesis. Acta Neuropathol. (Berl) 110, 208-221.
    • (2005) Acta Neuropathol. (Berl) , vol.110 , pp. 208-221
    • Hevner, R.F.1
  • 27
    • 0034234569 scopus 로고    scopus 로고
    • A neonatal lethal mutation in FGFR3 uncouples proliferation and differentiation of growth plate chondrocytes in embryos
    • Iwata T., Chen L., Li C., Ovchinnikov D. A., Behringer R. R., Francomano C. A. and Deng C. X. (2000) A neonatal lethal mutation in FGFR3 uncouples proliferation and differentiation of growth plate chondrocytes in embryos. Hum. Mol. Genet. 9, 1603-1613.
    • (2000) Hum. Mol. Genet , vol.9 , pp. 1603-1613
    • Iwata, T.1    Chen, L.2    Li, C.3    Ovchinnikov, D.A.4    Behringer, R.R.5    Francomano, C.A.6    Deng, C.X.7
  • 28
    • 0035363725 scopus 로고    scopus 로고
    • Highly activated Fgfr3 with the K644M mutation causes prolonged survival in severe dwarf mice
    • Iwata T., Li C. L., Deng C. X. and Francomano C. A. (2001) Highly activated Fgfr3 with the K644M mutation causes prolonged survival in severe dwarf mice. Hum. Mol. Genet. 10, 1255-1264.
    • (2001) Hum. Mol. Genet , vol.10 , pp. 1255-1264
    • Iwata, T.1    Li, C.L.2    Deng, C.X.3    Francomano, C.A.4
  • 30
    • 2942568167 scopus 로고    scopus 로고
    • Modulation of signalling by Sprouty: A developing story
    • Kim H. J. and Bar-Sagi D. (2004) Modulation of signalling by Sprouty: a developing story. Nat. Rev. Mol. Cell Biol. 5, 441-450.
    • (2004) Nat. Rev. Mol. Cell Biol , vol.5 , pp. 441-450
    • Kim, H.J.1    Bar-Sagi, D.2
  • 31
    • 0031900740 scopus 로고    scopus 로고
    • Signal transduction through MAP kinase cascades
    • Lewis T. S., Shapiro P. S. and Ahn N. G. (1998) Signal transduction through MAP kinase cascades. Adv. Cancer Res. 74, 49-139.
    • (1998) Adv. Cancer Res , vol.74 , pp. 49-139
    • Lewis, T.S.1    Shapiro, P.S.2    Ahn, N.G.3
  • 32
    • 0346788871 scopus 로고    scopus 로고
    • Sprouty: A controversial role in receptor tyrosine kinase signalling pathways
    • Li X., Wheldon L. and Heath J. K. (2003) Sprouty: a controversial role in receptor tyrosine kinase signalling pathways. Biochem. Soc. Trans. 31, 1445-1446.
    • (2003) Biochem. Soc. Trans , vol.31 , pp. 1445-1446
    • Li, X.1    Wheldon, L.2    Heath, J.K.3
  • 33
    • 0036223892 scopus 로고    scopus 로고
    • Cloning of the mouse Sef gene and comparative analysis of its expression with Fgf8 and Spry2 during embryogenesis
    • Lin W., Furthauer M., Thisse B., Thisse C., Jing N. and Ang S. L. (2002) Cloning of the mouse Sef gene and comparative analysis of its expression with Fgf8 and Spry2 during embryogenesis. Mech. Dev. 113, 163-168.
    • (2002) Mech. Dev , vol.113 , pp. 163-168
    • Lin, W.1    Furthauer, M.2    Thisse, B.3    Thisse, C.4    Jing, N.5    Ang, S.L.6
  • 34
    • 0035691974 scopus 로고    scopus 로고
    • FGF-induced lens cell proliferation and differentiation is dependent on MAPK (ERK1/2) signalling
    • Lovicu F. J. and McAvoy J. W. (2001) FGF-induced lens cell proliferation and differentiation is dependent on MAPK (ERK1/2) signalling. Development 128, 5075-5084.
    • (2001) Development , vol.128 , pp. 5075-5084
    • Lovicu, F.J.1    McAvoy, J.W.2
  • 35
  • 36
    • 30444441147 scopus 로고    scopus 로고
    • Sprouty proteins: Multifaceted negative-feedback regulators of receptor tyrosine kinase signaling
    • Mason J. M., Morrison D. J., Basson M. A. and Licht J. D. (2006) Sprouty proteins: multifaceted negative-feedback regulators of receptor tyrosine kinase signaling. Trends Cell Biol. 16, 45-54.
    • (2006) Trends Cell Biol , vol.16 , pp. 45-54
    • Mason, J.M.1    Morrison, D.J.2    Basson, M.A.3    Licht, J.D.4
  • 37
    • 0032719944 scopus 로고    scopus 로고
    • Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed
    • Minowada G., Jarvis L. A., Chi C. L., Neubuser A., Sun X., Hacohen N., Krasnow M. A. and Martin G. R. (1999) Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed. Development 126, 4465-4475.
    • (1999) Development , vol.126 , pp. 4465-4475
    • Minowada, G.1    Jarvis, L.A.2    Chi, C.L.3    Neubuser, A.4    Sun, X.5    Hacohen, N.6    Krasnow, M.A.7    Martin, G.R.8
  • 38
    • 0035512780 scopus 로고    scopus 로고
    • Mechanisms of cerebral cortical patterning in mice and humans
    • Monuki E. S. and Walsh C. A. (2001) Mechanisms of cerebral cortical patterning in mice and humans. Nat. Neurosci. 4(Suppl.), 1199-1206.
    • (2001) Nat. Neurosci , vol.4 , Issue.SUPPL. , pp. 1199-1206
    • Monuki, E.S.1    Walsh, C.A.2
  • 40
    • 0029935895 scopus 로고    scopus 로고
    • Graded activation of fibroblast growth factor receptor 3 by mutations causing achondroplasia and thanatophoric dysplasia
    • Naski M. C., Wang Q., Xu J. and Ornitz D. M. (1996) Graded activation of fibroblast growth factor receptor 3 by mutations causing achondroplasia and thanatophoric dysplasia. Nat. Genet. 13, 233-237.
    • (1996) Nat. Genet , vol.13 , pp. 233-237
    • Naski, M.C.1    Wang, Q.2    Xu, J.3    Ornitz, D.M.4
  • 41
    • 0028971813 scopus 로고
    • Phosphoinositide-specific phospholipase C and mitogenic signaling
    • Noh D. Y., Shin S. H. and Rhee S. G. (1995) Phosphoinositide-specific phospholipase C and mitogenic signaling. Biochim. Biophys. Acta 1242, 99-113.
    • (1995) Biochim. Biophys. Acta , vol.1242 , pp. 99-113
    • Noh, D.Y.1    Shin, S.H.2    Rhee, S.G.3
  • 42
    • 0037319169 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 3 signaling regulates the onset of oligodendrocyte terminal differentiation
    • Oh L. Y., Denninger A., Colvin J. S., Vyas A., Tole S., Ornitz D. M. and Bansal R. (2003) Fibroblast growth factor receptor 3 signaling regulates the onset of oligodendrocyte terminal differentiation. J. Neurosci. 23, 883-894.
    • (2003) J. Neurosci , vol.23 , pp. 883-894
    • Oh, L.Y.1    Denninger, A.2    Colvin, J.S.3    Vyas, A.4    Tole, S.5    Ornitz, D.M.6    Bansal, R.7
  • 43
    • 3042753337 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 1 is required for the proliferation of hippocampal progenitor cells and for hippocampal growth in mouse
    • Ohkubo Y., Uchida A. O., Shin D., Partanen J. and Vaccarino F. M. (2004) Fibroblast growth factor receptor 1 is required for the proliferation of hippocampal progenitor cells and for hippocampal growth in mouse. J. Neurosci. 24, 6057-6069.
    • (2004) J. Neurosci , vol.24 , pp. 6057-6069
    • Ohkubo, Y.1    Uchida, A.O.2    Shin, D.3    Partanen, J.4    Vaccarino, F.M.5
  • 44
    • 0026344226 scopus 로고
    • Developmental expression of two murine fibroblast growth factor receptors, flg and bek
    • Orr-Urtreger A., Givol D., Yayon A., Yarden Y. and Lonai P. (1991) Developmental expression of two murine fibroblast growth factor receptors, flg and bek. Development 113, 1419-1434.
    • (1991) Development , vol.113 , pp. 1419-1434
    • Orr-Urtreger, A.1    Givol, D.2    Yayon, A.3    Yarden, Y.4    Lonai, P.5
  • 45
    • 0027409017 scopus 로고
    • Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis
    • Peters K., Ornitz D., Werner S. and Williams L. (1993) Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis. Dev. Biol. 155, 423-430.
    • (1993) Dev. Biol , vol.155 , pp. 423-430
    • Peters, K.1    Ornitz, D.2    Werner, S.3    Williams, L.4
  • 47
    • 0033783352 scopus 로고    scopus 로고
    • Fibroblast growth factors, their receptors and signaling
    • Powers C. J., McLeskey S. W. and Wellstein A. (2000) Fibroblast growth factors, their receptors and signaling. Endocr. Relat. Cancer 7, 165-197.
    • (2000) Endocr. Relat. Cancer , vol.7 , pp. 165-197
    • Powers, C.J.1    McLeskey, S.W.2    Wellstein, A.3
  • 48
    • 0037232481 scopus 로고    scopus 로고
    • Fgfr3 expression by astrocytes and their precursors: Evidence that astrocytes and oligodendrocytes originate in distinct neuroepithelial domains
    • Pringle N. P., Yu W. P., Howell M., Colvin J. S., Ornitz D. M. and Richardson W. D. (2003) Fgfr3 expression by astrocytes and their precursors: evidence that astrocytes and oligodendrocytes originate in distinct neuroepithelial domains. Development 130, 93-102.
    • (2003) Development , vol.130 , pp. 93-102
    • Pringle, N.P.1    Yu, W.P.2    Howell, M.3    Colvin, J.S.4    Ornitz, D.M.5    Richardson, W.D.6
  • 49
    • 0034235176 scopus 로고    scopus 로고
    • Basic fibroblast growth factor (Fgf2) is necessary for cell proliferation and neurogenesis in the developing cerebral cortex
    • Raballo R., Rhee J., Lyn-Cook R., Leckman J. F., Schwartz M. L. and Vaccarino F. M. (2000) Basic fibroblast growth factor (Fgf2) is necessary for cell proliferation and neurogenesis in the developing cerebral cortex. J. Neurosci. 20, 5012-5023.
    • (2000) J. Neurosci , vol.20 , pp. 5012-5023
    • Raballo, R.1    Rhee, J.2    Lyn-Cook, R.3    Leckman, J.F.4    Schwartz, M.L.5    Vaccarino, F.M.6
  • 50
    • 0141742631 scopus 로고    scopus 로고
    • Reuss B. and von Bohlen und Halbach O. (2003) Fibroblast growth factors and their receptors in the central nervous system. Cell Tissue Res. 313, 139-157.
    • Reuss B. and von Bohlen und Halbach O. (2003) Fibroblast growth factors and their receptors in the central nervous system. Cell Tissue Res. 313, 139-157.
  • 51
    • 0242684548 scopus 로고    scopus 로고
    • Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops
    • Rubin C., Litvak V., Medvedovsky H., Zwang Y., Lev S. and Yarden Y. (2003) Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops. Curr. Biol. 13, 297-307.
    • (2003) Curr. Biol , vol.13 , pp. 297-307
    • Rubin, C.1    Litvak, V.2    Medvedovsky, H.3    Zwang, Y.4    Lev, S.5    Yarden, Y.6
  • 52
    • 33645893489 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinases 1/2 are required for adult retinal ganglion cell axon regeneration induced by fibroblast growth factor-2
    • Sapieha P. S., Hauswirth W. W. and Di Polo A. (2006) Extracellular signal-regulated kinases 1/2 are required for adult retinal ganglion cell axon regeneration induced by fibroblast growth factor-2. J. Neurosci. Res. 83, 985-995.
    • (2006) J. Neurosci. Res , vol.83 , pp. 985-995
    • Sapieha, P.S.1    Hauswirth, W.W.2    Di Polo, A.3
  • 53
    • 0034644539 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • Schlessinger J. (2000) Cell signaling by receptor tyrosine kinases. Cell 103, 211-225.
    • (2000) Cell , vol.103 , pp. 211-225
    • Schlessinger, J.1
  • 54
    • 16244423015 scopus 로고    scopus 로고
    • Sprouty2, a mouse deafness gene, regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling
    • Shim K., Minowada G., Coling D. E. and Martin G. R. (2005) Sprouty2, a mouse deafness gene, regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling. Dev. Cell 8, 553-564.
    • (2005) Dev. Cell , vol.8 , pp. 553-564
    • Shim, K.1    Minowada, G.2    Coling, D.E.3    Martin, G.R.4
  • 55
    • 1542317054 scopus 로고    scopus 로고
    • Loss of glutamatergic pyramidal neurons in frontal and temporal cortex resulting from attenuation of FGFR1 signaling is associated with spontaneous hyperactivity in mice
    • Shin D. M., Korada S., Raballo R., Shashikant C. S., Simeone A., Taylor J. R. and Vaccarino F. (2004) Loss of glutamatergic pyramidal neurons in frontal and temporal cortex resulting from attenuation of FGFR1 signaling is associated with spontaneous hyperactivity in mice. J. Neurosci. 24, 2247-2258.
    • (2004) J. Neurosci , vol.24 , pp. 2247-2258
    • Shin, D.M.1    Korada, S.2    Raballo, R.3    Shashikant, C.S.4    Simeone, A.5    Taylor, J.R.6    Vaccarino, F.7
  • 56
    • 0031661435 scopus 로고    scopus 로고
    • Fibroblast growth factors as multifunctional signaling factors
    • Szebenyi G. and Fallon J. F. (1999) Fibroblast growth factors as multifunctional signaling factors. Int, Rev. Cytol. 185, 45-106.
    • (1999) Int, Rev. Cytol , vol.185 , pp. 45-106
    • Szebenyi, G.1    Fallon, J.F.2
  • 57
    • 0029026103 scopus 로고
    • The cell cycle of the pseudostratified ventricular epithelium of the embryonic murine cerebral wall
    • Takahashi T., Nowakowski R. S. and Caviness V. S. Jr (1995) The cell cycle of the pseudostratified ventricular epithelium of the embryonic murine cerebral wall. J. Neurosci. 15, 6046-6057.
    • (1995) J. Neurosci , vol.15 , pp. 6046-6057
    • Takahashi, T.1    Nowakowski, R.S.2    Caviness Jr, V.S.3
  • 58
    • 0033361757 scopus 로고    scopus 로고
    • A novel skeletal dysplasia with developmental delay and acanthosis nigricans is caused by a Lys650Met mutation in the fibroblast growth factor receptor 3 gene
    • Tavormina P. L., Bellus G. A., Webster M. K. et al. (1999) A novel skeletal dysplasia with developmental delay and acanthosis nigricans is caused by a Lys650Met mutation in the fibroblast growth factor receptor 3 gene. Am. J. Hum. Genet. 64, 722-731.
    • (1999) Am. J. Hum. Genet , vol.64 , pp. 722-731
    • Tavormina, P.L.1    Bellus, G.A.2    Webster, M.K.3
  • 59
    • 29144532186 scopus 로고    scopus 로고
    • Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum
    • Tole S., Gutin G., Bhatnagar L., Remedios R. and Hebert J. M. (2006) Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum. Dev. Biol. 289, 141-151.
    • (2006) Dev. Biol , vol.289 , pp. 141-151
    • Tole, S.1    Gutin, G.2    Bhatnagar, L.3    Remedios, R.4    Hebert, J.M.5
  • 61
    • 2342483086 scopus 로고    scopus 로고
    • Promotion and attenuation of FGF signaling through the Ras-MAPK pathway
    • pe17
    • Tsang M. and Dawid I. B. (2004) Promotion and attenuation of FGF signaling through the Ras-MAPK pathway. Sci. STKE 2004, pe17.
    • (2004) Sci. STKE
    • Tsang, M.1    Dawid, I.B.2
  • 63
    • 0030064347 scopus 로고    scopus 로고
    • Constitutive activation of fibroblast growth factor receptor 3 by the transmembrane domain point mutation found in achondroplasia
    • Webster M. K. and Donoghue D. J. (1996) Constitutive activation of fibroblast growth factor receptor 3 by the transmembrane domain point mutation found in achondroplasia. EMBO J. 15, 520-527.
    • (1996) EMBO J , vol.15 , pp. 520-527
    • Webster, M.K.1    Donoghue, D.J.2
  • 64
    • 0035881420 scopus 로고    scopus 로고
    • COUP-TFI: An intrinsic factor for early regionalization of the neocortex
    • Zhou C., Tsai S. Y. and Tsai M. J. (2001) COUP-TFI: an intrinsic factor for early regionalization of the neocortex. Genes Dev. 15, 2054-2059.
    • (2001) Genes Dev , vol.15 , pp. 2054-2059
    • Zhou, C.1    Tsai, S.Y.2    Tsai, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.