Dissolution of Danazol Amorphous Solid Dispersions: Supersaturation and Phase Behavior as a Function of Drug Loading and Polymer Type

Molecular Pharmaceutics

Volumn 13, Issue 1, 2016, Pages 223-231

  Jackson, Matthew J ^a   Kestur, Umesh S ^b   Hussain, Munir A ^b   Taylor, Lynne S ^a  

^a PURDUE UNIVERSITY   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

amorphous solid dispersion; amorphous solubility; crystallization; dissolution; polymers; supersaturation

Indexed keywords

DANAZOL; HYDROXYPROPYLMETHYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE ACETATE SUCCINATE; POLYMER; POVIDONE; METHYLCELLULOSE;

AMORPHOUS SOLID DISPERSION; ARTICLE; CRYSTALLIZATION; DISPERSION; DRUG FORMULATION; DRUG SOLUBILITY; DRUG SOLUTION; KINETICS; PHASE TRANSITION; PRIORITY JOURNAL; ANALOGS AND DERIVATIVES; CHEMISTRY;

CRYSTALLIZATION; DANAZOL; HYPROMELLOSE DERIVATIVES; METHYLCELLULOSE; POLYMERS; POVIDONE;

EID: 84953440023     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/acs.molpharmaceut.5b00652     Document Type: Article

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