-
1
-
-
47749106894
-
Stoichiometry and physical chemistry of promiscuous aggregate-based inhibitors
-
Coan, K. E. D.; Shoichet, B. K. Stoichiometry and physical chemistry of promiscuous aggregate-based inhibitors J. Am. Chem. Soc. 2008, 130, 9606-9612
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 9606-9612
-
-
Coan, K.E.D.1
Shoichet, B.K.2
-
2
-
-
64549152003
-
Promiscuous aggregate-based inhibitors promote enzyme unfolding
-
Coan, K. E. D.; Maltby, D. A.; Burlingame, A. L.; Shoichet, B. K. Promiscuous aggregate-based inhibitors promote enzyme unfolding J. Med. Chem. 2009, 52, 2067-2075
-
(2009)
J. Med. Chem.
, vol.52
, pp. 2067-2075
-
-
Coan, K.E.D.1
Maltby, D.A.2
Burlingame, A.L.3
Shoichet, B.K.4
-
3
-
-
34249000046
-
A high-throughput screen for aggregation-based inhibition in a large compound library
-
Feng, B. Y.; Simeonov, A.; Jadhav, A.; Babaoglu, K.; Inglese, J.; Shoichet, B. K.; Austin, C. P. A high-throughput screen for aggregation-based inhibition in a large compound library J. Med. Chem. 2007, 50, 2385-2390
-
(2007)
J. Med. Chem.
, vol.50
, pp. 2385-2390
-
-
Feng, B.Y.1
Simeonov, A.2
Jadhav, A.3
Babaoglu, K.4
Inglese, J.5
Shoichet, B.K.6
Austin, C.P.7
-
4
-
-
15444366107
-
Concentration and pH dependent aggregation of hydrophobic drug molecules and relevance to oral bioavailability
-
Frenkel, Y. V.; Clark, A. D.; Das, K.; Wang, Y.-H.; Lewi, P. J.; Janssen, P. A. J.; Arnold, E. Concentration and pH dependent aggregation of hydrophobic drug molecules and relevance to oral bioavailability J. Med. Chem. 2005, 48, 1974-1983
-
(2005)
J. Med. Chem.
, vol.48
, pp. 1974-1983
-
-
Frenkel, Y.V.1
Clark, A.D.2
Das, K.3
Wang, Y.-H.4
Lewi, P.J.5
Janssen, P.A.J.6
Arnold, E.7
-
5
-
-
0037326367
-
Effects of synthetic lipids on solubilization and colloid stability of hydrophobic drugs
-
Pacheco, L. F.; Carmona-Ribeiro, A. M. Effects of synthetic lipids on solubilization and colloid stability of hydrophobic drugs J. Colloid Interface Sci. 2003, 258, 146-154
-
(2003)
J. Colloid Interface Sci.
, vol.258
, pp. 146-154
-
-
Pacheco, L.F.1
Carmona-Ribeiro, A.M.2
-
6
-
-
0141923641
-
Identification and prediction of promiscuous aggregating inhibitors among known drugs
-
Seidler, J.; McGovern, S. L.; Doman, T. N.; Shoichet, B. K. Identification and prediction of promiscuous aggregating inhibitors among known drugs J. Med. Chem. 2003, 46, 4477-4486
-
(2003)
J. Med. Chem.
, vol.46
, pp. 4477-4486
-
-
Seidler, J.1
McGovern, S.L.2
Doman, T.N.3
Shoichet, B.K.4
-
7
-
-
23844500772
-
High-throughput assays for promiscuous inhibitors
-
Feng, B. Y.; Shelat, A.; Doman, T. N.; Guy, R. K.; Shoichet, B. K. High-throughput assays for promiscuous inhibitors Nat. Chem. Biol. 2005, 3, 146-148
-
(2005)
Nat. Chem. Biol.
, vol.3
, pp. 146-148
-
-
Feng, B.Y.1
Shelat, A.2
Doman, T.N.3
Guy, R.K.4
Shoichet, B.K.5
-
8
-
-
0042071139
-
Formation of colloidal dispersions of organic materials in aqueous media by solvent shifting
-
Brick, M. C.; Palmer, H. J.; Whitesides, T. H. Formation of colloidal dispersions of organic materials in aqueous media by solvent shifting Langmuir 2003, 19, 6367-6380
-
(2003)
Langmuir
, vol.19
, pp. 6367-6380
-
-
Brick, M.C.1
Palmer, H.J.2
Whitesides, T.H.3
-
9
-
-
84875765122
-
Solid dispersions of α-Mangostin Improve its aqueous solubility through self-assembly of nanomicelles
-
Aisha, A. F. A.; Ismail, Z.; Abu-Salah, K. M.; Majid, A. M. S. A. Solid dispersions of α-Mangostin Improve its aqueous solubility through self-assembly of nanomicelles J. Pharm. Sci. 2011, 1-11
-
(2011)
J. Pharm. Sci.
, pp. 1-11
-
-
Aisha, A.F.A.1
Ismail, Z.2
Abu-Salah, K.M.3
Majid, A.M.S.A.4
-
10
-
-
0001732876
-
A method for preparing an aqueous colloidal dispersions of organic materials by using water-soluble polymers: Dispersion of β-carotene by polyvinylprrolidone
-
Tachibana, T.; Nakamura, A. A method for preparing an aqueous colloidal dispersions of organic materials by using water-soluble polymers: Dispersion of β-carotene by polyvinylprrolidone Kolloid Z. Z. Polym. 1965, 203, 130-133
-
(1965)
Kolloid Z. Z. Polym.
, vol.203
, pp. 130-133
-
-
Tachibana, T.1
Nakamura, A.2
-
11
-
-
84906326725
-
Critical Issues in Crystallization Practice
-
John Wiley & Sons, Inc. New York
-
Tung, H.-H.; Paul, E. L.; Midler, M.; McCauley, J. A. Critical Issues in Crystallization Practice. Crystallization of Organic Compounds: John Wiley & Sons, Inc.: New York, 2008.
-
(2008)
Crystallization of Organic Compounds
-
-
Tung, H.-H.1
Paul, E.L.2
Midler, M.3
McCauley, J.A.4
-
12
-
-
4344609538
-
Study of liquid-liquid demixing form drug solution
-
Lafferrère, L.; Hoff, C.; Veesler, S. Study of liquid-liquid demixing form drug solution J. Cryst. Growth 2004, 269, 550-557
-
(2004)
J. Cryst. Growth
, vol.269
, pp. 550-557
-
-
Lafferreìre, L.1
Hoff, C.2
Veesler, S.3
-
13
-
-
0347995143
-
Phase Transitions in Supersaturated Drug Solution
-
Veesler, S.; Lafferrère, L.; Garcia, E.; Hoff, C. Phase Transitions in Supersaturated Drug Solution Org. Process Res. Dev. 2003, 7, 983-989
-
(2003)
Org. Process Res. Dev.
, vol.7
, pp. 983-989
-
-
Veesler, S.1
Lafferreìre, L.2
Garcia, E.3
Hoff, C.4
-
14
-
-
0035525921
-
Nucleation, growth and pseudo-polymorphic behavior of citric acid as monitored in situ by attenuated total reflection fourier transform infrared spectroscopy
-
Groen, H.; Roberts, K. J. Nucleation, growth and pseudo-polymorphic behavior of citric acid as monitored in situ by attenuated total reflection fourier transform infrared spectroscopy J. Phys. Chem. B 2001, 105, 10723-10730
-
(2001)
J. Phys. Chem. B
, vol.105
, pp. 10723-10730
-
-
Groen, H.1
Roberts, K.J.2
-
15
-
-
0035244965
-
Novel Phenomenon of crystallization an emulsification of hydrophobic solute in aqueous solution
-
Maeda, K.; Aoyama, Y.; Fukui, K.; Hirota, S. Novel Phenomenon of crystallization an emulsification of hydrophobic solute in aqueous solution J. Colloid Interface Sci. 2001, 234, 217-222
-
(2001)
J. Colloid Interface Sci.
, vol.234
, pp. 217-222
-
-
Maeda, K.1
Aoyama, Y.2
Fukui, K.3
Hirota, S.4
-
16
-
-
84866733801
-
PH-induced precipitation behavior of weakly basic compounds: Determination of extent and duration of supersaturation using potentiometric titration and correlation to solid state properties
-
Hsieh, Y.; Ilevbare, G. A.; Van Eerdenbrugh, B.; Box, K.; Sanchez-Felix, M.; Taylor, L. S. pH-induced precipitation behavior of weakly basic compounds: Determination of extent and duration of supersaturation using potentiometric titration and correlation to solid state properties Pharm. Res. 2012, 20, 2738-2753
-
(2012)
Pharm. Res.
, vol.20
, pp. 2738-2753
-
-
Hsieh, Y.1
Ilevbare, G.A.2
Van Eerdenbrugh, B.3
Box, K.4
Sanchez-Felix, M.5
Taylor, L.S.6
-
17
-
-
52949150391
-
Effect of polymer type on the dissolution profile of amorphous solid dispersions containing felodipine
-
Konno, H.; Handa, T.; Alonzo, D. E.; Taylor, L. S. Effect of polymer type on the dissolution profile of amorphous solid dispersions containing felodipine Eur. J. Pharm. Biopharm. 2008, 20, 493-499
-
(2008)
Eur. J. Pharm. Biopharm.
, vol.20
, pp. 493-499
-
-
Konno, H.1
Handa, T.2
Alonzo, D.E.3
Taylor, L.S.4
-
18
-
-
77953171784
-
Understanding the behavior of amorphous pharmaceutical systems during dissolution
-
Alonzo, D.; Zhang, G.; Zhou, D.; Gao, Y.; Taylor, L. S. Understanding the behavior of amorphous pharmaceutical systems during dissolution Pharm. Res. 2010, 27, 608-618
-
(2010)
Pharm. Res.
, vol.27
, pp. 608-618
-
-
Alonzo, D.1
Zhang, G.2
Zhou, D.3
Gao, Y.4
Taylor, L.S.5
-
19
-
-
76649105411
-
Solubility advantage of amorphous pharmaceuticals I. A thermordynamic analysis
-
Murdande, S. B.; Pikal, M. J.; Shanker, R. M.; Bogner, R. H. Solubility advantage of amorphous pharmaceuticals I. A thermordynamic analysis J. Pharm. Sci. 2009, 99, 1254-1264
-
(2009)
J. Pharm. Sci.
, vol.99
, pp. 1254-1264
-
-
Murdande, S.B.1
Pikal, M.J.2
Shanker, R.M.3
Bogner, R.H.4
-
20
-
-
78651288987
-
Solubility advantage of amorphous pharmaceuticals II. Application of quantitative thermodynamic relationships for prediction of solubility enhancement in structurally diverse insoluble pharmaceuticals
-
Murdande, S. B.; Pikal, M. J.; Shanker, R. M.; Bogner, R. H. Solubility advantage of amorphous pharmaceuticals II. Application of quantitative thermodynamic relationships for prediction of solubility enhancement in structurally diverse insoluble pharmaceuticals Pharm. Res. 2010, 27, 2704-2714
-
(2010)
Pharm. Res.
, vol.27
, pp. 2704-2714
-
-
Murdande, S.B.1
Pikal, M.J.2
Shanker, R.M.3
Bogner, R.H.4
-
21
-
-
36849125484
-
Thermodynamic driving force in nucleation and growth processes
-
Hoffman, J. D. Thermodynamic driving force in nucleation and growth processes J. Chem. Phys. 1958, 29, 1192-1193
-
(1958)
J. Chem. Phys.
, vol.29
, pp. 1192-1193
-
-
Hoffman, J.D.1
-
22
-
-
33749447574
-
A comparison of the physical stability of amorphous felodipine and nifedipine systems
-
Marsac, P. J.; Konno, H.; Taylor, L. S. A comparison of the physical stability of amorphous felodipine and nifedipine systems Pharm. Res. 2006, 23, 2306-2316
-
(2006)
Pharm. Res.
, vol.23
, pp. 2306-2316
-
-
Marsac, P.J.1
Konno, H.2
Taylor, L.S.3
-
23
-
-
77955232982
-
A classification system to assess the crystallization tendency of organic molecules from undercooled melts
-
Baird, J. A.; Van Eerdenbrugh, B.; Taylor, L. S. A classification system to assess the crystallization tendency of organic molecules from undercooled melts J. Pharm. Sci. 2010, 99, 3787-3806
-
(2010)
J. Pharm. Sci.
, vol.99
, pp. 3787-3806
-
-
Baird, J.A.1
Van Eerdenbrugh, B.2
Taylor, L.S.3
-
24
-
-
77955234073
-
Crystallization tendency of active pharmaceutical ingredients following rapid solvent-evaporation - Classification and comparison with crystallization tendency from undercooled melts
-
Van Eerdenburgh, B.; Baird, J. A.; Taylor, L. S. Crystallization tendency of active pharmaceutical ingredients following rapid solvent-evaporation- classification and comparison with crystallization tendency from undercooled melts J. Pharm. Sci. 2010, 99, 3826-3838
-
(2010)
J. Pharm. Sci.
, vol.99
, pp. 3826-3838
-
-
Van Eerdenburgh, B.1
Baird, J.A.2
Taylor, L.S.3
-
26
-
-
0022061639
-
Fluorescence probes for critical micelle concentration
-
Ananthapadmanabhan, K. P.; Goddard, E. D.; Turro, N. J.; Kuo, P. L. Fluorescence probes for critical micelle concentration Langmuir 1985, 1, 352-355
-
(1985)
Langmuir
, vol.1
, pp. 352-355
-
-
Ananthapadmanabhan, K.P.1
Goddard, E.D.2
Turro, N.J.3
Kuo, P.L.4
-
27
-
-
0025384405
-
Fluorescence probe techniques used to study micelle formation in water-soluble block copolymers
-
Zhao, C.-L.; Winnik, M. A. Fluorescence probe techniques used to study micelle formation in water-soluble block copolymers Langmuir 1990, 6, 514-516
-
(1990)
Langmuir
, vol.6
, pp. 514-516
-
-
Zhao, C.-L.1
Winnik, M.A.2
-
28
-
-
0001696223
-
The spinodal approximation by the method of scattering in (n-hexane + n-tetradecafluorohexane)
-
Pozharskaya, G. I.; Kasapova, N. L.; Skripov, V. P.; Kolpakov, Y. D. The spinodal approximation by the method of scattering in (n-hexane + n-tetradecafluorohexane) J. Chem. Thermodyn. 1984, 16, 267-272
-
(1984)
J. Chem. Thermodyn.
, vol.16
, pp. 267-272
-
-
Pozharskaya, G.I.1
Kasapova, N.L.2
Skripov, V.P.3
Kolpakov, Y.D.4
-
29
-
-
33847285901
-
Determining the growth mechanism of tolazamide by induction time measurement
-
Kuldipkumar, A.; Kwon, G. S.; Zhang, G. G. Z. Determining the growth mechanism of tolazamide by induction time measurement Cryst. Growth Des. 2007, 7, 234-242
-
(2007)
Cryst. Growth Des.
, vol.7
, pp. 234-242
-
-
Kuldipkumar, A.1
Kwon, G.S.2
Zhang, G.G.Z.3
-
30
-
-
0037459494
-
Solution crystallization via a submerged liquid-liquid phase boundary: Oiling out
-
Bonnett, P. E.; Carpenter, K. J.; Dawson, S.; Davey, R. J. Solution crystallization via a submerged liquid-liquid phase boundary: oiling out Chem. Commun. 2003, 698-699
-
(2003)
Chem. Commun.
, pp. 698-699
-
-
Bonnett, P.E.1
Carpenter, K.J.2
Dawson, S.3
Davey, R.J.4
-
31
-
-
0034874245
-
Ritonavir: An extraordinary Example of Conformation Polymorphism
-
Bauer, J.; Spanton, S.; Henry, R.; Quick, J.; Dziki, W.; Porter, W.; Morris, J. Ritonavir: An extraordinary Example of Conformation Polymorphism Pharm. Res. 2001, 18, 859-866
-
(2001)
Pharm. Res.
, vol.18
, pp. 859-866
-
-
Bauer, J.1
Spanton, S.2
Henry, R.3
Quick, J.4
Dziki, W.5
Porter, W.6
Morris, J.7
-
32
-
-
0034886795
-
Physicochemical considerations in the preparation of amorphous ritonavir-poly(ethylene glycol) 8000 solid dispersions
-
Law, D.; Krill, S. L.; Schmitt, E. A.; Fort, J. J.; Qiu, Y.; Wang, W.; Porter, W. R. Physicochemical considerations in the preparation of amorphous ritonavir-poly(ethylene glycol) 8000 solid dispersions J. Pharm. Sci. 2001, 90, 1015-1025
-
(2001)
J. Pharm. Sci.
, vol.90
, pp. 1015-1025
-
-
Law, D.1
Krill, S.L.2
Schmitt, E.A.3
Fort, J.J.4
Qiu, Y.5
Wang, W.6
Porter, W.R.7
-
33
-
-
84861891898
-
Understanding polymer properties important for crystal growth inhibition - Impact of chemically diverse polymers on solution crystal growth of ritonavir
-
Ilevbare, G. A.; Liu, H.; Edgar, K. J.; Taylor, L. S. Understanding polymer properties important for crystal growth inhibition-Impact of chemically diverse polymers on solution crystal growth of ritonavir Cryst. Growth Des. 2012, 12, 3133-3143
-
(2012)
Cryst. Growth Des.
, vol.12
, pp. 3133-3143
-
-
Ilevbare, G.A.1
Liu, H.2
Edgar, K.J.3
Taylor, L.S.4
-
34
-
-
0031056536
-
Effects of sorbed water on the crystallization of indomethacin from the amorphous state
-
Andronis, V.; Yoshioka, M.; Zografi, G. Effects of sorbed water on the crystallization of indomethacin from the amorphous state J. Pharm. Sci. 1997, 86, 346-351
-
(1997)
J. Pharm. Sci.
, vol.86
, pp. 346-351
-
-
Andronis, V.1
Yoshioka, M.2
Zografi, G.3
-
35
-
-
0030298896
-
a and pH-solubility behavior of an ionizable cycle carbamate, (S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4- (trifluoromethyl)-2H-3,1-benzoxain-2-one (DMP 266)
-
a and pH-solubility behavior of an ionizable cycle carbamate, (S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1- benzoxain-2-one (DMP 266) Pharm. Dev. Technol. 1996, 1, 91-95
-
(1996)
Pharm. Dev. Technol.
, vol.1
, pp. 91-95
-
-
Rabel, S.R.1
Maurin, M.B.2
Rowe, S.M.3
Hussain, M.4
-
36
-
-
79959316849
-
A new validated liquid chromatographic method for the determination of loratadine and its impurities
-
Ramulu, G.; Kumar, Y. R.; Vyas, K.; Suryanarayana, M. V.; Mukkanti, K. A new validated liquid chromatographic method for the determination of loratadine and its impurities Sci. Pharm. 2011, 79, 277-291
-
(2011)
Sci. Pharm.
, vol.79
, pp. 277-291
-
-
Ramulu, G.1
Kumar, Y.R.2
Vyas, K.3
Suryanarayana, M.V.4
Mukkanti, K.5
-
37
-
-
33845491449
-
Interpreting Steep Dose-Response Curves in Early Inhibitor Discovery
-
Shoichet, B. K. Interpreting Steep Dose-Response Curves in Early Inhibitor Discovery J. Med. Chem. 2006, 49, 7274-7277
-
(2006)
J. Med. Chem.
, vol.49
, pp. 7274-7277
-
-
Shoichet, B.K.1
-
38
-
-
0004260819
-
Hydrophilic polymers. Associating polymers containing fluorocarbon hydrophobic units
-
Amis, E. J.; Hu, N.; Seery, T. A. P.; Hogen-Esch, T. E.; Yassini, M.; Hwang, F.; Hydrophilic polymers. Associating polymers containing fluorocarbon hydrophobic units. Adv. Chem. 248, 1996, 279-302.
-
(1996)
Adv. Chem.
, vol.248
, pp. 279-302
-
-
Amis, E.J.1
Hu, N.2
Seery, T.A.P.3
Hogen-Esch, T.E.4
Yassini, M.5
Hwang, F.6
-
40
-
-
0032523141
-
Temperature dependence of critical micelle concentration of polyoxyethylenated non-ionic surfactants
-
Chen, L.-J.; Lin, S.-Y.; Huang, C.-C.; Chen, E.-M. Temperature dependence of critical micelle concentration of polyoxyethylenated non-ionic surfactants Colloid. Surface. A 1998, 135, 175-181
-
(1998)
Colloid. Surface. A
, vol.135
, pp. 175-181
-
-
Chen, L.-J.1
Lin, S.-Y.2
Huang, C.-C.3
Chen, E.-M.4
-
41
-
-
0001468891
-
Effect of temperature on the critical micelle concentration of nonionic detergents. Thermodynamics of micelle formation
-
Schick, M. J. Effect of temperature on the critical micelle concentration of nonionic detergents. Thermodynamics of micelle formation J. Phys. Chem. 1963, 67, 1796-1799
-
(1963)
J. Phys. Chem.
, vol.67
, pp. 1796-1799
-
-
Schick, M.J.1
-
42
-
-
50549182056
-
The effect of temperature on the critical micelle concentration of some paraffin-chain salts
-
Flockhart, B. D. The effect of temperature on the critical micelle concentration of some paraffin-chain salts J. Colloid Sci. 1961, 16, 484-492
-
(1961)
J. Colloid Sci.
, vol.16
, pp. 484-492
-
-
Flockhart, B.D.1
-
43
-
-
0014550327
-
Some solution properties of certain surface active N-alkylpyridinium Halides I. Effect of temperature on the critical micelle concentrations
-
Stead, J. A.; Taylor, H. Some solution properties of certain surface active N-alkylpyridinium Halides I. Effect of temperature on the critical micelle concentrations J. Colloid Interface Sci. 1969, 30, 482-488
-
(1969)
J. Colloid Interface Sci.
, vol.30
, pp. 482-488
-
-
Stead, J.A.1
Taylor, H.2
-
44
-
-
0035885532
-
Effect of temperature on critical micelle concentration and thermodynamic potentials of micellization of anionic ammonium dodecyl sulfate and cationic octadecyl trimethyl ammonium chloride
-
Kang, K.-H.; Kim, H.-U.; Lim, K.-H. Effect of temperature on critical micelle concentration and thermodynamic potentials of micellization of anionic ammonium dodecyl sulfate and cationic octadecyl trimethyl ammonium chloride Colloid. Surface. A 2001, 189, 113-121
-
(2001)
Colloid. Surface. A
, vol.189
, pp. 113-121
-
-
Kang, K.-H.1
Kim, H.-U.2
Lim, K.-H.3
-
46
-
-
0003444425
-
Chemical and engineering thermodynamics
-
3 rd ed. John Wiley and Sons
-
Sandler, S. I. Chemical and engineering thermodynamics, 3 rd ed.; John Wiley and Sons: New York, 1999.
-
(1999)
New York
-
-
Sandler, S.I.1
-
47
-
-
0001522674
-
Studies on glass II. The transition between the glassy and liquid states in the case of glucose
-
Parks, G. S.; Huffman, H. M.; Cattoir, F. R. Studies on glass II. The transition between the glassy and liquid states in the case of glucose J. Phys. Chem. 1928, 31, 1366-1379
-
(1928)
J. Phys. Chem.
, vol.31
, pp. 1366-1379
-
-
Parks, G.S.1
Huffman, H.M.2
Cattoir, F.R.3
-
48
-
-
0001539587
-
Studies on glass. XI. Some thermodynamic relations of glassy and alpha-crystalline glucose
-
Parks, G. S.; Snyder, L. J.; Cattoir, F. R. Studies on glass. XI. Some thermodynamic relations of glassy and alpha-crystalline glucose J. Chem. Phys. 1934, 2, 595-598
-
(1934)
J. Chem. Phys.
, vol.2
, pp. 595-598
-
-
Parks, G.S.1
Snyder, L.J.2
Cattoir, F.R.3
-
49
-
-
1142303337
-
What is the true solubility advantage for amorphous pharmaceuticals?
-
Hancock, B. C.; Parks, M. What is the true solubility advantage for amorphous pharmaceuticals? Pharm. Res. 2000, 17, 397-404
-
(2000)
Pharm. Res.
, vol.17
, pp. 397-404
-
-
Hancock, B.C.1
Parks, M.2
|