Compound C inhibits macrophage chemotaxis through an AMPK-independent mechanism

Biochemical and Biophysical Research Communications

Volumn 469, Issue 3, 2016, Pages 515-520

  Lee, Youngyi ^a,b   Park, Byung Hyun ^b   Bae, Eun Ju ^a  

^a Woosuk University   (South Korea)

^b Chonbuk National University Medical School   (South Korea)

Author keywords

AMPK; Chemotaxis; Compound C; Glucose uptake; Inflammation; Macrophage

Indexed keywords

ANTIINFLAMMATORY AGENT; COMPOUND C; FOCAL ADHESION KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; (6-(4-(2-PIPERIDIN-1-YLETHOXY)PHENYL))-3-PYRIDIN-4-YLPYRAZOLO(1,5-A)PYRIMIDINE; CYTOKINE; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE;

3T3 CELL LINE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL LINE RAW 264.7; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; ENZYME MECHANISM; IN VITRO STUDY; INSULIN RESISTANCE; INSULIN SENSITIVITY; INTRACELLULAR SIGNALING; MACROPHAGE CHEMOTAXIS; MACROPHAGE MIGRATION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; ADIPOCYTE; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL COMMUNICATION; CELL CULTURE; DOSE RESPONSE; DRUG EFFECTS; IMMUNOLOGY; MACROPHAGE; METABOLISM; MOUSE; RAW 264.7 CELL LINE; SIGNAL TRANSDUCTION;

ADIPOCYTES; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CELL COMMUNICATION; CELLS, CULTURED; CHEMOTAXIS; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; MACROPHAGES; MICE; PYRAZOLES; PYRIMIDINES; RAW 264.7 CELLS; SIGNAL TRANSDUCTION;

EID: 84953410363     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.12.015     Document Type: Article

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