-
1
-
-
20044387026
-
IKK-β links inflammation to obesity-induced insulin resistance
-
Arkan MC, Hevener AL, Greten FR, Maeda S, Li ZW, Long JM, Wynshaw-Boris A, Poli G, Olefsky J & Karin M 2005 IKK-β links inflammation to obesity-induced insulin resistance. Nature Medicine 11 191-198. (doi:10.1038/nm1185).
-
(2005)
Nature Medicine
, vol.11
, pp. 191-198
-
-
Arkan, M.C.1
Hevener, A.L.2
Greten, F.R.3
Maeda, S.4
Li, Z.W.5
Long, J.M.6
Wynshaw-boris, A.7
Poli, G.8
Olefsky, J.9
Karin, M.10
-
2
-
-
84859977895
-
Sirtuins mediate mammalian metabolic responses to nutrient availability
-
Chalkiadaki A & Guarente L 2012 Sirtuins mediate mammalian metabolic responses to nutrient availability. Nature Reviews. Endocrinology 8 287-296. (doi:10.1038/nrendo.2011.225)
-
(2012)
Nature Reviews. Endocrinology
, vol.8
, pp. 287-296
-
-
Chalkiadaki, A.1
Guarente, L.2
-
3
-
-
27444437321
-
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
-
Cinti S, Mitchell G, Barbatelli G, Murano I, Ceresi E, Faloia E, Wang S, Fortier M, Greenberg AS & Obin MS 2005 Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. Journal of Lipid Research 46 2347-2355. (doi:10.1194/jlr.M500294-JLR200).
-
(2005)
Journal of Lipid Research
, vol.46
, pp. 2347-2355
-
-
Cinti, S.1
Mitchell, G.2
Barbatelli, G.3
Murano, I.4
Ceresi, E.5
Faloia, E.6
Wang, S.7
Fortier, M.8
Greenberg, A.S.9
Obin, M.S.10
-
4
-
-
7744226149
-
Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects
-
1657-1669
-
Clement K, Viguerie N, Poitou C, Carette C, Pelloux V, Curat CA, Sicard A, Rome S, Benis A, Zucker JD et al. 2004 Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects. FASEB J 1657-1669. (doi:10.1096/fj.04-2204com).
-
(2004)
FASEB J
-
-
Clement, K.1
Viguerie, N.2
Poitou, C.3
Carette, C.4
Pelloux, V.5
Curat, C.A.6
Sicard, A.7
Rome, S.8
Benis, A.9
Zucker, J.D.10
-
5
-
-
2442583529
-
Cloning and characterization of the promoter region of human focal adhesion kinase gene: nuclear factor kB and p53 binding sites
-
Golubovskaya V, Kaur A & Cance W 2004 Cloning and characterization of the promoter region of human focal adhesion kinase gene: nuclear factor kB and p53 binding sites. Biochimica et Biophysica Acta 1678 111-125. (doi:10.1016/j.bbaexp.2004.03.002).
-
(2004)
Biochimica et Biophysica Acta
, vol.1678
, pp. 111-125
-
-
Golubovskaya, V.1
Kaur, A.2
Cance, W.3
-
6
-
-
33845866857
-
Inflammation and metabolic disorders
-
Hotamisligil GS 2006 Inflammation and metabolic disorders. Nature 444 860-867. (doi:10.1038/nature05485).
-
(2006)
Nature
, vol.444
, pp. 860-867
-
-
Hotamisligil, G.S.1
-
7
-
-
79952392892
-
Increased expression of macrophage-inducible C-type lectin in adipose tissue of obese mice and humans
-
Ichioka M, Suganami T, Tsuda N, Shirakawa I, Hirata Y, Satoh-Asahara N, Shimoda Y, Tanaka M, Kim-Saijo M, Miyamoto Y et al. 2011 Increased expression of macrophage-inducible C-type lectin in adipose tissue of obese mice and humans. Diabetes 60 819-826. (doi:10.2337/db10-0864).
-
(2011)
Diabetes
, vol.60
, pp. 819-826
-
-
Ichioka, M.1
Suganami, T.2
Tsuda, N.3
Shirakawa, I.4
Hirata, Y.5
Satoh-asahara, N.6
Shimoda, Y.7
Tanaka, M.8
Kim-saijo, M.9
Miyamoto, Y.10
-
8
-
-
33745216724
-
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
-
Kanda H, Tateya S, Tamori Y, Kotani K, Hiasa K, Kitazawa R, Kitazawa S, Miyachi H, Maeda S, Egashira K et al. 2006 MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. Journal of Clinical Investigation 116 1494-1505. (doi:10.1172/JCI26498).
-
(2006)
Journal of Clinical Investigation
, vol.116
, pp. 1494-1505
-
-
Kanda, H.1
Tateya, S.2
Tamori, Y.3
Kotani, K.4
Hiasa, K.5
Kitazawa, R.6
Kitazawa, S.7
Miyachi, H.8
Maeda, S.9
Egashira, K.10
-
9
-
-
20044374023
-
Design and validation of a histological scoring system for nonalcoholic fatty liver disease
-
Kleiner DE, Brunt EM, Van Natta M, Behling C, Contos MJ, Cummings OW, Ferrell LD, Liu YC, Torbenson MS, Unalp-Arida A et al. 2005 Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 41 1313-1321. (doi:10.1002/hep.20701).
-
(2005)
Hepatology
, vol.41
, pp. 1313-1321
-
-
Kleiner, D.E.1
Brunt, E.M.2
Van Natta, M.3
Behling, C.4
Contos, M.J.5
Cummings, O.W.6
Ferrell, L.D.7
Liu, Y.C.8
Torbenson, M.S.9
Unalp-arida, A.10
-
10
-
-
80755152884
-
Subcutaneous adipose tissue macrophage infiltration is associated with hepatic and visceral fat deposition, hyperinsulinemia, and stimulation of NF-kB stress pathway
-
Le KA, Mahurkar S, Alderete TL, Hasson RE, Adam TC, Kim JS, Beale E, Xie C, Greenberg AS, Allayee H et al. 2011 Subcutaneous adipose tissue macrophage infiltration is associated with hepatic and visceral fat deposition, hyperinsulinemia, and stimulation of NF-kB stress pathway. Diabetes 60 2802-2809. (doi:10.2337/db10-1263).
-
(2011)
Diabetes
, vol.60
, pp. 2802-2809
-
-
Le, K.A.1
Mahurkar, S.2
Alderete, T.L.3
Hasson, R.E.4
Adam, T.C.5
Kim, J.S.6
Beale, E.7
Xie, C.8
Greenberg, A.S.9
Allayee, H.10
-
11
-
-
63249112836
-
Overexpression of SIRT1 protects pancreatic β-cells against cytokine toxicity by suppressing the nuclear factor-kB signaling pathway
-
Lee JH, Song MY, Song EK, Kim EK, Moon WS, Han MK, Park JW, Kwon KB & Park BH 2009 Overexpression of SIRT1 protects pancreatic β-cells against cytokine toxicity by suppressing the nuclear factor-kB signaling pathway. Diabetes 58 344-351. (doi:10.2337/db07-1795).
-
(2009)
Diabetes
, vol.58
, pp. 344-351
-
-
Lee, J.H.1
Song, M.Y.2
Song, E.K.3
Kim, E.K.4
Moon, W.S.5
Han, M.K.6
Park, J.W.7
Kwon, K.B.8
Park, B.H.9
-
12
-
-
33846026712
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
-
Lumeng CN, Bodzin JL & Saltiel AR 2007 Obesity induces a phenotypic switch in adipose tissue macrophage polarization. Journal of Clinical Investigation 117 175-184. (doi:10.1172/JCI29881).
-
(2007)
Journal of Clinical Investigation
, vol.117
, pp. 175-184
-
-
Lumeng, C.N.1
Bodzin, J.L.2
Saltiel, A.R.3
-
13
-
-
57649128307
-
Requirement of inducible nitric-oxide synthase in lipopolysaccharide-mediated Src induction and macrophage migration
-
Maa MC, Chang MY, Chen YJ, Lin CH, Yu CJ, Yang YL, Li J, Chen PR, Tang CH, Lei HY et al. 2008 Requirement of inducible nitric-oxide synthase in lipopolysaccharide-mediated Src induction and macrophage migration. Journal of Biological Chemistry 283 31408-31416. (doi:10.1074/jbc.M801158200).
-
(2008)
Journal of Biological Chemistry
, vol.283
, pp. 31408-31416
-
-
Maa, M.C.1
Chang, M.Y.2
Chen, Y.J.3
Lin, C.H.4
Yu, C.J.5
Yang, Y.L.6
Li, J.7
Chen, P.R.8
Tang, C.H.9
Lei, H.Y.10
-
14
-
-
36849005372
-
A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways
-
Nguyen MT, Favelyukis S, Nguyen AK, Reichart D, Scott PA, Jenn A, Liu-Bryan R, Glass CK, Neels JG & Olefsky JM 2007 A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways. Journal of Biological Chemistry 282 35279-35292. (doi:10.1074/jbc.M706762200)
-
(2007)
Journal of Biological Chemistry
, vol.282
, pp. 35279-35292
-
-
Nguyen, M.T.1
Favelyukis, S.2
Nguyen, A.K.3
Reichart, D.4
Scott, P.A.5
Jenn, A.6
Liu-bryan, R.7
Glass, C.K.8
Neels, J.G.9
Olefsky, J.M.10
-
15
-
-
77951918926
-
Macrophages, inflammation, and insulin resistance
-
Olefsky JM & Glass CK 2010 Macrophages, inflammation, and insulin resistance. Annual Review of Physiology 72 219-246. (doi:10.1146/annurev-physiol-021909-135846)
-
(2010)
Annual Review of Physiology
, vol.72
, pp. 219-246
-
-
Olefsky, J.M.1
Glass, C.K.2
-
16
-
-
0037509990
-
Focal adhesion kinase: the first ten years
-
Parsons JT 2003 Focal adhesion kinase: the first ten years. Journal of Cell Science 116 1409-1416. (doi:10.1242/jcs.00373)
-
(2003)
Journal of Cell Science
, vol.116
, pp. 1409-1416
-
-
Parsons, J.T.1
-
17
-
-
77956677458
-
Myeloid deletion of SIRT1 induces inflammatory signaling in response to environmental stress
-
Schug TT, Xu Q, Gao H, Peres-da-Silva A, Draper DW, Fessler MB, Purushotham A & Li X 2010 Myeloid deletion of SIRT1 induces inflammatory signaling in response to environmental stress. Molecular and Cellular Biology 30 4712-4721. (doi:10.1128/MCB.00657-10)
-
(2010)
Molecular and Cellular Biology
, vol.30
, pp. 4712-4721
-
-
Schug, T.T.1
Xu, Q.2
Gao, H.3
Peres-da-silva, A.4
Draper, D.W.5
Fessler, M.B.6
Purushotham, A.7
Li, X.8
-
18
-
-
66149115196
-
Role of SIRT1 in regulation of LPS-or two ethanol metabolites-induced TNF-a production in cultured macrophage cell lines
-
Shen Z, Ajmo JM, Rogers CQ, Liang X, Le L, Murr MM, Peng Y & You M 2009 Role of SIRT1 in regulation of LPS-or two ethanol metabolites-induced TNF-a production in cultured macrophage cell lines. American Journal of Physiology. Gastrointestinal and Liver Physiology 296 G1047-G1053. (doi:10.1152/ajpgi.00016.2009)
-
(2009)
American Journal of Physiology. Gastrointestinal and Liver Physiology
, vol.296
, pp. G1047-G1053
-
-
Shen, Z.1
Ajmo, J.M.2
Rogers, C.Q.3
Liang, X.4
Le, L.5
Murr, M.M.6
Peng, Y.7
You, M.8
-
19
-
-
35548943962
-
JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity
-
Solinas G, Vilcu C, Neels JG, Bandyopadhyay GK, Luo JL, Naugler W, Grivennikov S, Wynshaw-Boris A, Scadeng M, Olefsky JM et al. 2007 JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity. Cell Metabolism 386-397. (doi:10.1016/j.cmet.2007.09.011)
-
(2007)
Cell Metabolism
, pp. 386-397
-
-
Solinas, G.1
Vilcu, C.2
Neels, J.G.3
Bandyopadhyay, G.K.4
Luo, J.L.5
Naugler, W.6
Grivennikov, S.7
Wynshaw-boris, A.8
Scadeng, M.9
Olefsky, J.M.10
-
20
-
-
33846323706
-
Role of the Toll-like receptor 4/NF-kB pathway in saturated fatty acid-induced inflam-matory changes in the interaction between adipocytes and macrophages
-
Suganami T, Tanimoto-Koyama K, Nishida J, Itoh M, Yuan X, Mizuarai S, Kotani H, Yamaoka S, Miyake K, Aoe S et al. 2007 Role of the Toll-like receptor 4/NF-kB pathway in saturated fatty acid-induced inflam-matory changes in the interaction between adipocytes and macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology 27 84-91. (doi:10.1161/01.ATV.0000251608.09329.9a)
-
(2007)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.27
, pp. 84-91
-
-
Suganami, T.1
Tanimoto-koyama, K.2
Nishida, J.3
Itoh, M.4
Yuan, X.5
Mizuarai, S.6
Kotani, H.7
Yamaoka, S.8
Miyake, K.9
Aoe, S.10
-
21
-
-
31044456529
-
CCR2 modulates inflammatory and metabolic effects of high-fat feeding
-
Weisberg SP, Hunter D, Huber R, Lemieux J, Slaymaker S, Vaddi K, Charo I, Leibel RL & Ferrante AW Jr.2006 CCR2 modulates inflammatory and metabolic effects of high-fat feeding. Journal of Clinical Investigation 116 115-124. (doi:10.1172/JCI24335)
-
(2006)
Journal of Clinical Investigation
, vol.116
, pp. 115-124
-
-
Weisberg, S.P.1
Hunter, D.2
Huber, R.3
Lemieux, J.4
Slaymaker, S.5
Vaddi, K.6
Charo, I.7
Leibel, R.L.8
Ferrante Jr., A.W.9
-
22
-
-
84869805159
-
The full capacity of AICAR to reduce obesity-induced inflammation and insulin resistance requires myeloid SIRT1
-
Yang Z, Wang X, He Y, Qi L, Yu L, Xue B & Shi H 2012 The full capacity of AICAR to reduce obesity-induced inflammation and insulin resistance requires myeloid SIRT1. PLoS ONE 7 e49935. (doi:10.1371/journal. pone.0049935)
-
(2012)
PLoS ONE
, vol.7
-
-
Yang, Z.1
Wang, X.2
He, Y.3
Qi, L.4
Yu, L.5
Xue, B.6
Shi, H.7
-
23
-
-
77349087078
-
SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity
-
Yoshizaki T, Schenk S, Imamura T, Babendure JL, Sonoda N, Bae EJ, Oh DY, Lu M, Milne JC, Westphal C et al. 2010 SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity. American Journal of Physiology 298 E419-E428. (doi:10.1152/ajpendo.00417.2009)
-
(2010)
American Journal of Physiology
, vol.298
, pp. E419-E428
-
-
Yoshizaki, T.1
Schenk, S.2
Imamura, T.3
Babendure, J.L.4
Sonoda, N.5
Bae, E.J.6
Oh, D.Y.7
Lu, M.8
Milne, J.C.9
Westphal, C.10
-
24
-
-
77951211562
-
SIRT1 suppresses activator protein-1 transcriptional activity and cyclooxygenase-2 expression in macrophages
-
Zhang R, Chen HZ, Liu JJ, Jia YY, Zhang ZQ, Yang RF, Zhang Y, Xu J, Wei YS, Liu DP et al. 2010 SIRT1 suppresses activator protein-1 transcriptional activity and cyclooxygenase-2 expression in macrophages. Journal of Biological Chemistry 285 7097-7110. (doi:10.1074/jbc.M109.038604).
-
(2010)
Journal of Biological Chemistry
, vol.285
, pp. 7097-7110
-
-
Zhang, R.1
Chen, H.Z.2
Liu, J.J.3
Jia, Y.Y.4
Zhang, Z.Q.5
Yang, R.F.6
Zhang, Y.7
Xu, J.8
Wei, Y.S.9
Liu, D.P.10
|