Platinum and PARP Inhibitor Resistance Due to Overexpression of MicroRNA-622 in BRCA1-Mutant Ovarian Cancer

Cell Reports

Volumn 14, Issue 3, 2016, Pages 429-439

  Choi, Young Eun ^a   Meghani, Khyati ^a   Brault, Marie Eve ^a   Leclerc, Lucas ^a   He, Yizhou J ^a   Day, Tovah A ^a   Elias, Kevin M ^b   Drapkin, Ronny ^c   Weinstock, David M ^a   Dao, Fanny ^d   Shih, Karin K ^d   Matulonis, Ursula ^a   Levine, Douglas A ^d   Konstantinopoulos, Panagiotis A ^a   Chowdhury, Dipanjan ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC METAL COMPLEX; CARBOPLATIN; CISPLATIN; DOUBLE STRANDED DNA; KU ANTIGEN; MICRORNA; MICRORNA 622; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; OLAPARIB; UNCLASSIFIED DRUG; VELIPARIB; ANTINEOPLASTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; BRCA1 PROTEIN; CELL NUCLEUS ANTIGEN; DNA BINDING PROTEIN; PLATINUM COMPLEX; SIGNAL PEPTIDE; TP53BP1 PROTEIN, HUMAN; TUMOR SUPPRESSOR P53 BINDING PROTEIN 1; XRCC6 PROTEIN, HUMAN; XRCC6 PROTEIN, MOUSE;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL CYCLE; CELL CYCLE S PHASE; CELL VIABILITY; CONTROLLED STUDY; DISEASE FREE SURVIVAL; DNA END JOINING REPAIR; DNA REPAIR; DOUBLE STRANDED DNA BREAK; FEMALE; GENE EXPRESSION; GENE MUTATION; GENE OVEREXPRESSION; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; OVARIAN CANCER CELL LINE; OVARY CARCINOMA; OVERALL SURVIVAL; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; GENETICS; METABOLISM; MORTALITY; NUCLEOTIDE SEQUENCE; OVARY TUMOR; PATHOLOGY; RNA INTERFERENCE; SEQUENCE ALIGNMENT; TUMOR CELL LINE;

ANIMALS; ANTIGENS, NUCLEAR; ANTINEOPLASTIC AGENTS; BASE SEQUENCE; BRCA1 PROTEIN; CELL LINE, TUMOR; DISEASE-FREE SURVIVAL; DNA END-JOINING REPAIR; DNA-BINDING PROTEINS; FEMALE; HOMOLOGOUS RECOMBINATION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KU AUTOANTIGEN; MICE; MICRORNAS; OLIGONUCLEOTIDES, ANTISENSE; ORGANOPLATINUM COMPOUNDS; OVARIAN NEOPLASMS; POLY(ADP-RIBOSE) POLYMERASE INHIBITORS; RNA INTERFERENCE; SEQUENCE ALIGNMENT; TUMOR SUPPRESSOR P53-BINDING PROTEIN 1;

EID: 84953315302     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.12.046     Document Type: Article

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